Article
Veterinary Sciences
Oystein Angen, Martin Weiss Nielsen, Per Lofstrom, Anders Rhod Larsen, Niels Bohse Hendriksen
Summary: The study reveals that LA-MRSA is present in the air of pig farms, but at low levels above 50 meters, and the proportion of MRSA-positive soil samples decreases with increasing distance from the farm building. Among individuals working outside the pig farm for a whole day, only one individual's nasal sample tested positive for LA-MRSA, indicating that airborne spread of MRSA from pig farms may not be a significant route for human contamination in such cases.
FRONTIERS IN VETERINARY SCIENCE
(2021)
Article
Environmental Sciences
Jenny Lexen, Maria Bernander, Ian Cotgreave, Patrik L. Andersson
Summary: Studies have shown that human exposure to SVOCs in car cabins is influenced by both air and dust concentrations. It is suggested to broaden the scope of research to include all relevant exposure routes for a more comprehensive assessment of human exposure.
ENVIRONMENT INTERNATIONAL
(2021)
Article
Environmental Sciences
Klaudia Pytel, Renata Marcinkowska, Bozena Zabiegala
Summary: The study found that excessive use of essential oils rich in terpenes in spa salons can significantly increase the concentration of TVOCs in indoor air, with terpenes accounting for 22% to 86% of total TVOCs. The type of essential oils used also has an impact on the indoor air chemical composition.
ENVIRONMENTAL SCIENCE AND POLLUTION RESEARCH
(2021)
Article
Medicine, Research & Experimental
Jiaqian Wang, Yuan Xue, Liang Zhou
Summary: By using bioinformatics analysis, this study explored the differences in immune mechanisms and diagnostic markers between SpA and RA. The results showed that differentially expressed genes (DEGs) were mainly enriched in cell chemotaxis, lymphocyte activation, primary immunodeficiency and other immune responses. The differences in immune cells between SpA, RA and normal controls were mainly concentrated in B and T lymphocytes, macrophages and dendritic cells. C19orf12 + S1PR3 was found to be most associated with these immune cells and can be used as a diagnostic marker for this type of immune diseases. Additionally, MZB1 + XIST was closely related to T cells, NK cells and dendritic cells, and may serve as a marker to distinguish between the two diseases.
JOURNAL OF TRANSLATIONAL MEDICINE
(2022)
Article
Microbiology
Xiaoshen Li, Longfei Xie, Honghao Huang, Zhi Li, Guihua Li, Peng Liu, Danyu Xiao, Xucai Zhang, Wenguang Xiong, Zhenling Zeng
Summary: Livestock-associated methicillin-resistant Staphylococcus aureus (LA-MRSA) is a zoonotic microorganism that poses a significant public health concern. This study investigated the transmission and occurrence of MRSA in a slaughterhouse environment and examined its antimicrobial resistance and genetic characterization. The findings suggest that MRSA is more prevalent in swine samples compared to other sources, and there is potential transmission between swine, humans, and the environment. The MRSA isolates also exhibited multidrug resistance phenotypes.
FRONTIERS IN MICROBIOLOGY
(2022)
Review
Engineering, Environmental
Jyoti Bhardwaj, Seongkyeol Hong, Junbeom Jang, Chang-Ho Han, Jaegil Lee, Jaesung Jang
Summary: This review discusses recent advancements in measuring pathogenic airborne viruses, emphasizing the importance of different methods for virus collection and analysis. Special focus is placed on the effects of air sampling on the sampled viruses.
JOURNAL OF HAZARDOUS MATERIALS
(2021)
Article
Infectious Diseases
Catherine Grace Elijah, Jessie D. Trujillo, Cassandra K. Jones, Taeyong Kwon, Charles R. Stark, Konner R. Cool, Chad B. Paulk, Natasha N. Gaudreault, Jason C. Woodworth, Igor Morozov, Carmina Gallardo, Jordan T. Gebhardt, Jurgen A. Richt
Summary: Monitoring ASFV in feed through sequencing batches can reduce viral contamination, but not eliminate it entirely. The described subsampling method accurately detects ASFV genetic material in bulk ingredients. Further research is necessary to explore other mitigation techniques for reducing ASFV contamination in feed.
TRANSBOUNDARY AND EMERGING DISEASES
(2022)
Article
Veterinary Sciences
Xiaowen Li, Zhiqiang Hu, Mingyu Fan, Xiaogang Tian, Weisheng Wu, Wenchao Gao, Lujie Bian, Xiaoxue Jiang
Summary: African swine fever (ASF) is a highly contagious and economically devastating disease in China's pig industry. This study provides the first evidence of aerosol transmission of ASFV under field conditions, highlighting the importance of studying aerosol transmission and developing strategies for creating low-risk environments for pig herds.
FRONTIERS IN VETERINARY SCIENCE
(2023)
Article
Environmental Sciences
Baptiste Delaunay, Nathalie Sauret, Jerome Ledauphin
Summary: This study developed a new method for extracting PAHs in PUF and applied it to environmental survey. The method uses a small portion of the PUF disk and ethanol for extraction, making it environmentally friendly. The PAH concentrations varied depending on the site and time.
Article
Engineering, Environmental
Hector Jorquera, Ana Maria Villalobos
Summary: Air quality modeling is commonly used to study gaseous pollution around industrial areas. This study proposes a new methodology, FUSTA, which combines fuzzy clustering with standard AQM to apportion industrial gaseous emissions sources. The methodology is applied in a central Chilean industrial zone to identify major sources of ambient SO2 and episodes associated with emissions from a copper smelter.
JOURNAL OF HAZARDOUS MATERIALS
(2023)
Article
Economics
Collin W. H. Wong, Tommy King Yin Cheung, Anming Zhang
Summary: The change of routes at an airport has a significant impact on airlines' revenue and the local economy. Past studies have neglected the effects of new route additions or revisions on the global aviation network and direct/transfer demands. This study proposes a data analytic approach to identify and assess new and lasting routes, considering the connectivity potential and overall network dynamics. The approach utilizes geographical relationships between airports and historical route supply data to make informed decisions and enhance airport connectivity-potential.
TRANSPORTATION RESEARCH PART A-POLICY AND PRACTICE
(2023)
Article
Virology
Marek Walczak, Anna Szczotka-Bochniarz, Jacek Zmudzki, Malgorzata Juszkiewicz, Krzesimir Szymankiewicz, Krzysztof Niemczuk, Daniel Perez-Nunez, Lihong Liu, Yolanda Revilla
Summary: African swine fever (ASF) is a highly economically important and dangerous disease for the Suidae family. This study analyzed data from animal trials to identify the risk and importance of non-invasive sampling for ASF detection. It found that blood sampling provided the highest probability of detection, with PCR-positive blood samples being detected earlier and more frequently than oral and rectal swabs. These findings highlight the essential role of blood sampling in accurate diagnosis of ASF.
Article
Biochemical Research Methods
Rachel L. Davey, Erick J. Mattson, J. Alex Huffman
Summary: The study demonstrates that gas-phase ozone and nitrogen dioxide can react with proteins in the atmosphere to form nitrotyrosine, potentially impacting human health. Bovine serum albumin samples exposed to urban air in Denver, Colorado were used to investigate protein modification under ambient conditions, highlighting the formation of nitrotyrosine and its relevance to atmospheric exposure studies.
ANALYTICAL AND BIOANALYTICAL CHEMISTRY
(2022)
Article
Immunology
Sorour Farzi, Mohsen Rezazadeh, Ahmadreza Mirhosseini, Mohammad Amin Rezazadeh, Farhan Houshyar, Mohammad Hossein Ahmadi
Summary: This study investigated the molecular epidemiology and antibiotic resistance pattern of MRSA clinical isolates from Southern Iran, revealing different genetic types and resistance patterns among the strains.
ACTA MICROBIOLOGICA ET IMMUNOLOGICA HUNGARICA
(2021)
Article
Environmental Sciences
Varatharajan Prasannavenkadesan, Chockalingam Singaravelu
Summary: This paper presents a preliminary study on controlling pollutant emissions from an industrial furnace. The stack sampling technique was used to monitor the quantity of pollutants in the furnace smoke. The data collection points were selected based on disturbances from upstream and downstream. Results showed that coal tar fuel reduced the emission of SO2 and N2 compared to regular furnace oil. The proposed operational adjustment attenuates pollutant emissions and reduces environmental impact.
ENVIRONMENTAL SCIENCE AND POLLUTION RESEARCH
(2023)
Article
Infectious Diseases
Patrick Munk, Vibe Dalhoff Andersen, Leonardo de Knegt, Marie Stengaard Jensen, Berith Elkaer Knudsen, Oksana Lukjancenko, Hanne Mordhorst, Julie Clasen, Yvonne Agerso, Anders Folkesson, Sunje Johanna Pamp, Hakan Vigre, Frank Moller Aarestrup
JOURNAL OF ANTIMICROBIAL CHEMOTHERAPY
(2017)
Article
Public, Environmental & Occupational Health
V. D. Andersen, L. V. De Knegt, P. Munk, M. S. Jensen, Y. Agerso, F. M. Aarestrup, H. Vigre
EPIDEMIOLOGY AND INFECTION
(2017)
Article
Public, Environmental & Occupational Health
A. C. Birkegard, A. K. Ersboll, T. Halasa, J. Clasen, A. Folkesson, H. Vigre, N. Toft
EPIDEMIOLOGY AND INFECTION
(2017)
Article
Veterinary Sciences
Anna Camilla Birkegard, Vibe Dalhoff Andersen, Tariq Halasa, Vibeke Frokjaer Jensen, Nils Toft, Hakan Vigre
PREVENTIVE VETERINARY MEDICINE
(2017)
Article
Public, Environmental & Occupational Health
V. D. Andersen, P. Munk, L. V. de Knegt, M. S. Jensen, F. M. Aarestrup, H. Vigre
EPIDEMIOLOGY AND INFECTION
(2018)
Article
Microbiology
Patrick Munk, Berith Elkaer Knudsen, Oksana Lukjancenko, Ana Sofia Ribeiro Duarte, Liese Van Gompel, Roosmarijn E. C. Luiken, Lidwien A. M. Smit, Heike Schmitt, Alejandro Dorado Garcia, Rasmus Borup Hansen, Thomas Nordahl Petersen, Alex Bossers, Etienne Ruppe, Ole Lund, Tine Hald, Sunje Johanna Pamp, Hakan Vigre, Dick Heederik, Jaap A. Wagenaar, Dik Mevius, Frank M. Aarestrup
NATURE MICROBIOLOGY
(2018)
Article
Infectious Diseases
Lina M. Cavaco, Frank Hansen, Shazad Mushtaq, Robert L. R. Hill, Neil Woodford, Simon Le Hello, Rene S. Hendriksen, Anette M. Hammerum, Henrik Hasman
JOURNAL OF ANTIMICROBIAL CHEMOTHERAPY
(2019)
Article
Microbiology
Magdalena Zajac, Pawel Sztromwasser, Valeria Bortolaia, Pimlapas Leekitcharoenphon, Lina M. Cavaco, Anna Zietek-Barszcz, Rene S. Hendriksen, Dariusz Wasyl
FRONTIERS IN MICROBIOLOGY
(2019)
Correction
Microbiology
Magdalena Zajac, Pawel Sztromwasser, Valeria Bortolaia, Pimlapas Leekitcharoenphon, Lina M. Cavaco, Anna Zietek-Barszcz, Rene S. Hendriksen, Dariusz Wasyl
FRONTIERS IN MICROBIOLOGY
(2019)
Article
Infectious Diseases
Louise Roer, Frank Hansen, Henrik Hasman, Anette M. Hammerum, Lina Maria Cavaco
INTERNATIONAL JOURNAL OF ANTIMICROBIAL AGENTS
(2020)
Article
Chemistry, Medicinal
Elnaz Harifi Mood, Lise Goltermann, Camilla Brolin, Lina M. Cavaco, Alireza Japoni Nejad, Niloofar Yavari, Nicki Frederiksen, Henrik Franzyk, Peter E. Nielsen
Summary: The peptidomimetic CEP-136 significantly potentiates the antibacterial activity of clinically important antibiotics against several human pathogens, showing strong synergy with some combinations resulting in over 50-fold reduction in antibiotic concentration. Mechanistic studies suggest the potentiation effect arises from permeabilization of the Gram-negative bacteria's outer membrane lipopolysaccharide layer. Additionally, CEP-136 exhibits low toxicity to mammalian cells and mice, making it a promising compound for developing adjuvants to combat infections by multidrug-resistant Gram-negative bacteria.
ACS INFECTIOUS DISEASES
(2021)
Article
Food Science & Technology
Konstantinos Koutsoumanis, Ana Allende, Avelino Alvarez-Ordonez, Declan Bolton, Sara Bover-Cid, Marianne Chemaly, Robert Davies, Alessandra De Cesare, Lieve Herman, Friederike Hilbert, Roland Lindqvist, Maarten Nauta, Giuseppe Ru, Marion Simmons, Panagiotis Skandamis, Elisabetta Suffredini, Hector Arguello, Thomas Berendonk, Lina Maria Cavaco, William Gaze, Heike Schmitt, Ed Topp, Beatriz Guerra, Ernesto Liebana, Pietro Stella, Luisa Peixe
Summary: The study evaluated the role of food-producing environments in the emergence and spread of antimicrobial resistance in EU plant-based food production, terrestrial animals, and aquaculture. It identified key sources and transmission routes, highlighting the importance of fecal fertilizers, irrigation, and water sources. Highest priority bacteria and genes were identified in various sources, emphasizing the need for mitigation measures and data on ARB and ARG diversity. Further epidemiological studies on AMR and its control in food production environments at the EU level are urgently needed.
Article
Chemistry, Medicinal
Mirko Iubatti, Isabel Maicas Gabas, Lina M. Cavaco, Elnaz Harifi Mood, Ernest Lim, Federica Bonanno, Niloofar Yavari, Camilla Brolin, Peter E. Nielsen
Summary: This study presents a series of diaminobutanoic acid (DAB) dendrons as novel carriers for the delivery of antisense antibacterial peptide nucleic acids (PNAs). These dendron-PNA conjugates exhibit specific antisense antimicrobial bactericidal activity against Escherichia coli and Klebsiella pneumoniae, while showing low toxicity to human cells. One selected compound shows high stability in mouse and human serum, and demonstrates in vivo activity against a multidrug-resistant E. coli.
ACS INFECTIOUS DISEASES
(2022)
Article
Multidisciplinary Sciences
Gonzalo Yebra, Joshua D. Harling-Lee, Samantha Lycett, Frank M. Aarestrup, Gunhild Larsen, Lina M. Cavaco, Keun Seok Seo, Sam Abraham, Jacqueline M. Norris, Tracy Schmidt, Marthie M. Ehlers, Daniel O. Sordelli, Fernanda R. Buzzola, Wondwossen A. Gebreyes, Juliano L. Goncalves, Marcos Dos Santos, Zunita Zakaria, Vera L. M. Rall, Orla M. Keane, Dagmara A. Niedziela, Gavin K. Paterson, Mark A. Holmes, Tom C. Freeman, J. Ross Fitzgerald
Summary: This study traces the evolutionary history of bovine Staphylococcus aureus and identifies seven major endemic clones causing bovine mastitis globally. The clones originated from four independent host-jump events from humans up to 2,500 years ago. The expansion of these clones coincided with the commercialization and industrialization of dairy farming. Differences in host transmission events between humans and cows were also discovered, highlighting high-risk clones that pose threats to veterinary and human health.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
(2022)
Article
Microbiology
Christopher Rensing, Arshnee Moodley, Lina M. Cavaco, Sylvia Franke Mcdevitt
MICROBIOLOGY SPECTRUM
(2018)
