Biomarker responses in mudskipper (Periophthalmus waltoni) from the coastal areas of the Persian Gulf with oil pollution

A suite of 5 different biomarker responses were selected and measured in 3 different phases of detoxification process in mudskipper Periophthalmus waltoni from 3 different stations including Soltani Inlet, Shif Island and Amen Port in Bushehr coastal area of the Persian Gulf. The selected biomarkers were 7-ethoxyresorufin O-deethylase (EROD), glutathione S-transferase (GST), biliary fluorescent aromatic compounds (FACs), DNA damage using the Comet assay and micronucleus (MN). Spatial variations in biomarker responses were observed in different sites. EROD, GST, FACs, DNA damage and MN were significantly elevated in mudskippers in the most oil impacted site (Soltani inlet). Based on the assessments, bile metabolites, EROD and GST induction appear to be sensitive to polycyclic aromatic hydrocarbons (PAHs) and can be considered as complementary biomarkers; therefore P. waltoni has the potential to be used as a bioindicator in these types of ecosystems.. (C) 2012 Elsevier B.V. All rights reserved.