Article
Immunology
Ruth Owen, Emily R. Thompson, Samuel J. Tingle, Ibrahim K. Ibrahim, Derek M. Manas, Steve A. White, Colin H. Wilson
Summary: This study investigated the impact of recipient BMI on graft outcomes after pancreas transplantation. It was found that increasing recipient BMI had a significant impact on graft survival, especially for recipients on dialysis with a BMI >30 kg/m(2). However, a specific cutoff value for BMI that could predict outcomes accurately was not identified.
Article
Endocrinology & Metabolism
Marco La Marra, Ciro Rosario Ilardi, Ines Villano, Rita Polito, Maria Raffella Sibillo, Marina Franchetti, Angela Caggiano, Francesca Strangio, Giovanni Messina, Vincenzo Monda, Girolamo Di Maio, Antonietta Messina
Summary: This study investigates the relationship between obesity, executive functions, and body image in a nonclinical population from southern Italy. The results suggest that better executive functioning predicts a decrease in BMI, partially due to a reduction in avoidance behaviors.
FRONTIERS IN ENDOCRINOLOGY
(2022)
Article
Nutrition & Dietetics
Julianna Bailey, Stefanie Krick, Kevin R. Fontaine
Summary: This article reviews the prevalence and impact of overweight and obesity in cystic fibrosis patients, as well as the existing treatment evidence. It emphasizes the importance of personalized interdisciplinary approaches and calls for further research on optimal strategies for addressing overweight and obesity in this population.
Article
Microbiology
Olivia Raglan, David A. MacIntyre, Anita Mitra, Yun S. Lee, Ann Smith, Nada Assi, Jaya Nautiyal, Sanjay Purkayastha, Marc J. Gunter, Hani Gabra, Julian R. Marchesi, Phillip R. Bennett, Maria Kyrgiou
Summary: Obese women have a significantly different vaginal microbiota composition and higher levels of local inflammation compared to non-obese women. Bariatric surgery does not alter the vaginal microbiota, but those who experience the greatest weight loss post-surgery are more likely to have a Lactobacillus-dominant VMB.
Article
Endocrinology & Metabolism
Yanbin Du, Yuan Lv, Wenting Zha, Nan Zhou, Xiuqin Hong
Summary: This study examined the association between BMI and COVID-19 severity and mortality through a meta-analysis of 16 observational studies involving 109,881 patients. The findings showed a linear dose-response relationship between BMI and critical COVID-19 and mortality, with patients with BMI > 30 kg/m(2) at higher risk. Age and obesity were also found to impact this association.
METABOLISM-CLINICAL AND EXPERIMENTAL
(2021)
Article
Endocrinology & Metabolism
Radwan Kassir, Pierre Gimet, David Hupin, Claire Boutet, Jean-Claude Barthelemy, Frederic Roche, Sebastien Celle
Summary: This study aims to explore the relationship between the brain and obesity, using two different measures of obesity (BMI and BFI). The results show that in the elderly population, the relationship between the brain and obesity may differ from that in younger subjects. Higher BMI and BFI are associated with increased grey matter volume in the left cerebellum and increased white matter volume in the cerebellum and near the right medial orbital gyrus. This suggests that the cerebellum may be one of the key structures related to obesity.
FRONTIERS IN ENDOCRINOLOGY
(2023)
Article
Health Care Sciences & Services
Jong-Seop Koo, So Young Kim
Summary: This study found that being underweight is generally associated with an increased prevalence of hearing loss in the Korean adult population, while obesity may be related to a decreased risk of hearing loss.
JOURNAL OF PERSONALIZED MEDICINE
(2022)
Article
Medicine, General & Internal
Guy Rozen, Gabby Elbaz-Greener, Gilad Margolis, Ibrahim Marai, Edwin K. Heist, Jeremy N. Ruskin, Shemy Carasso, Ariel Roguin, Edo Y. Birati, Offer Amir
Summary: This study investigated the distribution of BMI and its relationship with in-hospital mortality in stroke patients in the U.S. It found a reverse J-shaped relationship between body mass index and in-hospital mortality, with higher BMI associated with lower mortality during hospitalization.
JOURNAL OF CLINICAL MEDICINE
(2022)
Review
Endocrinology & Metabolism
Abduladheem Turki Jalil, Ameer A. Alameri, Rumi Iqbal Doewes, Amr A. El-Sehrawy, Irfan Ahmad, Pushpamala Ramaiah, Mustafa M. Kadhim, Hamzah H. Kzar, R. Sivaraman, Rosario Mireya Romero-Parra, Mohammad Javed Ansari, Yasser Fakri Mustafa
Summary: In this meta-analysis, an inverse association between circulating AGEs and body mass index among adults was observed, while the association between dietary AGEs and body mass index was inconclusive. Individuals with obesity had lower levels of circulating AGEs compared to those without obesity. The type of AGEs may contribute to the heterogeneity observed.
FRONTIERS IN ENDOCRINOLOGY
(2022)
Article
Endocrinology & Metabolism
Xiao-cong Liu, Yu Huang, Kenneth Lo, Yu-qing Huang, Ji-yan Chen, Ying-qing Feng
Summary: The study found that the Waist-BMI Ratio can independently predict overall and cardiovascular mortality risk in a dose-response relationship, with ROC curve analysis showing it to be a better discriminator of mortality compared to BMI, WC, and waist-to-height ratio.
FRONTIERS IN ENDOCRINOLOGY
(2021)
Article
Pediatrics
Jasmine F. Plows, Paige K. Berger, Roshonda B. Jones, Elizabeth Campbell, Emily Leibovitch, Tanya L. Alderete, Michelle Horowitz, Xavier Pi-Sunyer, Dympna Gallagher, Michael Goran
Summary: The study aims to develop and validate a prediction model for fat mass in infants using easily accessible measurements such as weight and length. The model accurately predicts infant fat mass using multivariable linear regression analysis and fractional polynomials.
JOURNAL OF PEDIATRICS
(2022)
Article
Nutrition & Dietetics
Fernanda Velluzzi, Andrea Deledda, Maurizio Onida, Andrea Loviselli, Roberto Crnjar, Giorgia Sollai
Summary: Smell plays an important role in food choice and body weight regulation. Impaired or loss of smell is associated with malnutrition and altered eating behaviors. The obesity epidemic is influenced by various factors, including the environment and decreased olfactory function. Obese individuals have lower olfactory function and there is a negative correlation between BMI and olfactory scores. Normosmic obese patients have lower BMI compared to hyposmic ones.
Article
Nutrition & Dietetics
Zaida Aguera, Cristina Vintro-Alcaraz, Isabel Baenas, Roser Granero, Isabel Sanchez, Jessica Sanchez-Gonzalez, Jose M. Menchon, Susana Jimenez-Murcia, Janet Treasure, Fernando Fernandez-Aranda
Summary: The study compared the impact of four specific BMI profiles on the severity of symptoms and treatment outcomes for patients with eating disorders. It was found that lifetime obesity is associated with higher general psychopathology and personality traits, while extreme weight changes are linked to higher psychopathology but do not affect the severity of ED symptoms. Patients with persistent obesity had higher dropout rates.
Article
Oncology
Jiajing Wang, Hongmei Zhang, Faisal I. Rezwan, Caroline Relton, S. Hasan Arshad, John W. Holloway
Summary: Pre-adolescent DNAm is associated with BMI status transition from pre- to post-adolescence, a relationship that may be gender-specific. Consistent associations between genomic methylation patterns and BMI status transition were found in two independent cohorts, highlighting the significance of this gender-specific association.
CLINICAL EPIGENETICS
(2021)
Article
Nutrition & Dietetics
Ying Jiang, Xiaomin Zhang, Tianwei Xu, Weiqi Hong, Zhiqi Chen, Xiang Gao, Renying Xu
Summary: This study evaluated the secular difference in BMI among Chinese older adults and found that BMI gradually increased from 2014 to 2020. The prevalence of overweight and obesity significantly increased, especially in the 70-79-year age group, while the prevalence of underweight decreased. These findings highlight the importance of a balanced diet and physical exercise in maintaining an optimal BMI range for the aging population.
FRONTIERS IN NUTRITION
(2022)
Article
Rheumatology
Hylton B. Menz, Michelle Marshall, Martin J. Thomas, Trishna Rathod-Mistry, George M. Peat, Edward Roddy
Summary: Objective Hallux valgus is a common and disabling condition. The present study aimed to identify factors associated with the incidence and progression of hallux valgus. Methods Participants from a population-based prospective cohort study, the Clinical Assessment Study of the Foot, were included. Baseline and 7-year follow-up data were collected through health questionnaires and self-assessment using line drawings. Results The study included 1,482 participants, and 30.4% had hallux valgus at baseline. Incident hallux valgus occurred in 20.1% of participants and was associated with age, physical health, foot pain, and constrictive footwear. Progression of hallux valgus occurred in 33.6% of participants but was not associated with any baseline factors. Conclusion Hallux valgus develops in one-fifth of adults aged 50 years and older over a 7-year period and is related to age, physical health, foot pain, and previous use of constrictive footwear. The progression of hallux valgus can occur in one-third of adults. These findings indicate that changes in first metatarsophalangeal joint alignment may still occur beyond the age of 50 years.
ARTHRITIS CARE & RESEARCH
(2023)
Article
Rheumatology
Michelle Marshall, Milica Blagojevic-Bucknall, Trishna Rathod-Mistry, Martin J. Thomas, John J. Edwards, George Peat, Hylton B. Menz, Edward Roddy
Summary: The study identified four distinct trajectories of foot pain over a 7-year period, highlighting the associations between persistent pain and factors such as obesity and hallux valgus. Further investigation into targeting modifiable prognostic factors is needed for long-term outcomes in individuals with foot pain.
ARTHRITIS CARE & RESEARCH
(2023)
Article
Rheumatology
Yuanyuan Wang, Ega Wirayoda Pontoh, Sultana Monira Hussain, Yuan Z. Lim, Graeme Jones, Catherine L. Hill, Anita E. Wluka, Andrew Tonkin, Changhai Ding, Flavia M. Cicuttini
Summary: This study found evidence for the involvement of vascular pathology in the progression of knee osteoarthritis and suggested that targeting atherosclerosis could improve outcomes in knee osteoarthritis.
Article
Rheumatology
Karl B. Landorf, Michelle R. Kaminski, Shannon E. Munteanu, Gerard Zammit, Hylton B. Menz
Summary: This study found that individuals with plantar heel pain (PHP) stood for longer periods of time, had difficulty accessing suitable footwear, and wore shoes with harder heels compared to individuals without PHP.
MUSCULOSKELETAL CARE
(2023)
Article
Surgery
Sarah M. Manewell, Sarah J. Aitken, Vanessa L. Nube, Anna M. Crawford, Maria I. Constantino, Stephen M. Twigg, Hylton B. Menz, Catherine Sherrington, Serene S. Paul
Summary: This study aimed to determine the incidence of minor and major amputation among inpatients with diabetes-related foot ulceration (DFU) over 4 years, and to investigate the factors associated with these amputations. The results showed that the incidence of minor amputation during the patient's index DFU-related admission was 28%, while the incidence of major amputation was 6%. Minor amputation was associated with requiring revascularisation, while major amputation was associated with more comorbidities and receiving care for a mental health condition.
ANZ JOURNAL OF SURGERY
(2023)
Article
Rheumatology
Hylton B. B. Menz, Jamie J. J. Allan, Andrew K. K. Buldt, Karl B. B. Landorf, Flavia M. M. Cicuttini, Edward Roddy, Shannon E. E. Munteanu
Summary: This study aimed to determine whether neuropathic pain is a feature of first metatarsophalangeal (MTP) joint osteoarthritis (OA). By comparing pain questionnaire results and related factors, the study found that a significant proportion of individuals with first MTP joint OA experience neuropathic pain, which may partly explain the suboptimal responses to commonly used treatments. Screening for neuropathic pain may be useful in selecting targeted interventions and improving clinical outcomes.
ARTHRITIS CARE & RESEARCH
(2023)
Article
Orthopedics
Ameer Nor Azhar, Shannon E. Munteanu, Hylton B. Menz
Summary: This study compared standing balance and walking stability in older women wearing supportive footwear and minimalist footwear, and investigated participants' perceptions of comfort, ease of use, and fit. The results showed no significant differences in balance performance between the two footwear styles. However, participants perceived the supportive footwear to be more attractive, easier to put on and off but heavier, and more comfortable in certain areas. Most participants felt more stable in the supportive footwear and would consider wearing them to reduce their risk of falling.
JOURNAL OF FOOT AND ANKLE RESEARCH
(2023)
Article
Rheumatology
Matthew Cotchett, Cassandra Bramston, Shan Bergin, Hylton B. Menz, Rebecca Jessup
Summary: Hallux valgus negatively impacts health-related quality of life. Patients with hallux valgus often lack access to high-quality educational resources and face a variable experience with healthcare professionals. There is a need for the development of high-quality educational resources and better support from healthcare professionals.
MUSCULOSKELETAL CARE
(2023)
Review
Rheumatology
Polly Q. X. Lim, Merridy J. Lithgow, Michelle R. Kaminski, Karl B. Landorf, Hylton B. Menz, Shannon E. Munteanu
Summary: This systematic review aims to investigate the efficacy of non-surgical interventions for midfoot osteoarthritis (OA). The review included six trials and found that arch contouring foot orthoses, shoe stiffening inserts, and corticosteroid injections may be effective for midfoot OA. However, the methodological quality of the included trials was poor, and more rigorous randomized trials are needed to evaluate the efficacy of non-surgical interventions for midfoot OA.
RHEUMATOLOGY INTERNATIONAL
(2023)
Article
Orthopedics
Hylton B. Menz, Polly Q. X. Lim, Sheree E. Hurn, Karen J. Mickle, Andrew K. Buldt, Matthew P. Cotchett, Edward Roddy, Anita E. Wluka, Bircan Erbas, Mehak Batra, Shannon E. Munteanu
Summary: This study aimed to evaluate the effectiveness of a nonsurgical intervention for reducing pain associated with hallux valgus and determine the feasibility of conducting a randomized trial. The results showed that the current intervention is not feasible, primarily due to low adherence and the impact of COVID-19.
JOURNAL OF FOOT AND ANKLE RESEARCH
(2023)
Article
Rheumatology
Mahnuma M. Estee, Yuanyuan Wang, Stephane Heritier, Donna M. Urquhart, Flavia M. Cicuttini, Mark A. Kotowicz, Sharon L. Brennan-Olsen, Julie A. Pasco, Anita E. Wluka
Summary: A study conducted on men over a 10-year period found that negative beliefs regarding back pain were associated with an increased likelihood of developing high-intensity pain and/or high disability.
