Journal
ENVIRONMENTAL TOXICOLOGY
Volume 27, Issue 2, Pages 109-116Publisher
WILEY
DOI: 10.1002/tox.20618
Keywords
bioaccumulation; rice crop; Pirycularia orizae; triazole; pesticide; tebuconazole; fungicide
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Funding
- Ministerio de Educacion y Ciencia (MEyC), Comision Interministerial de Ciencia y Tecnologia, Spain [AGL-2002-04532-C03-01, BES-2003-0163]
- Fundacao de Amparo a Pesquisa do Estado de Sao Paulo (Brazil) [FAPESP 2007/08371-7]
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This research work investigated the bioconcentration of tebuconazole [(+/-)-alpha-[2-(4-chlorophenyl)ethyl]-alpha-(1,1-dimethylethyl)-1H-1,2,4-triazole-1-ethanol] fungicide in zebrafish (Danio rerio) under laboratory conditions and a first-order kinetic pesticide dissipation in the water. The concentrations of tebuconazole fitted to an equivalent nonlinear kinetic type model which allowed the calculation of the following parameters: bioconcentration factor (38.80 L kg-1), time to reach maximum fish concentration (6 days), maximum concentration in fish (0.0075 mu g mg-1), half-life in fish (24 days) and time needed for the fish to eliminate 95% of the maximum concentration (105 days). These calculations permitted the establishment of theoretical reference limit values for human consumption of fish and the establishment of safe limits for the water pesticide concentration. The data would also be useful in safe strategies associated with fishery activities that are conducted in aquatic regions close to crops using tebuconazole. The information will contribute to enlarge the tebuconazole toxicokinetics database of aquatic organisms. (C) 2011 Wiley Periodicals, Inc. Environ Toxicol, 2012.
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