Article
Environmental Sciences
Raquel Sampaio Jacob, Cristiano V. M. Araujo, Lucilaine Valeria de Souza Santos, Victor Rezende Moreira, Yuri Abner Rocha Lebron, Lisete Celina Lange
Summary: This study aimed to evaluate the risks of four different pharmaceutical active compounds, showing that omeprazole was acutely toxic, while other PhACs exhibited chronic toxicity. The study also found that the chemicals' mode of action seemed to determine their repellency or attractiveness, highlighting the potential environmental disturbance they may cause.
ENVIRONMENTAL POLLUTION
(2021)
Article
Environmental Sciences
Gisela de Assis Martini, Cassiana Carolina Montagner, William Viveiros, Gilson Alves Quinaglia, Daniela Dayrell Franca, Nivea Cristina Guedes Munin, Monica Lopes-Ferreira, Sizue Ota Rogero, Jose Roberto Rogero
Summary: Contaminants of emerging concern (CECs) are receiving global attention due to their widespread presence in water bodies. This study aimed to assess the occurrence of some target CECs in surface water in Sao Paulo state and their adverse effects on non-target species, using a combined chemical and biological approach. The results showed that even at low concentrations, CECs can cause adverse effects on aquatic biota, highlighting the importance of new chemical indicators for water quality monitoring.
ENVIRONMENTAL SCIENCE AND POLLUTION RESEARCH
(2021)
Review
Engineering, Environmental
Duduku Saidulu, Bramha Gupta, Ashok Kumar Gupta, Partha Sarathi Ghosal
Summary: The presence of emerging contaminants in the aquatic environment poses global concerns due to their harmful impacts on the biosphere. Efforts to remove these compounds from wastewater have become a significant focus in environmental management. Advanced biological systems coupled with physical and chemical processes are emerging as promising treatment options, especially in regions where concentrations of harmful compounds exceed safe levels.
JOURNAL OF ENVIRONMENTAL CHEMICAL ENGINEERING
(2021)
Review
Engineering, Environmental
Mohammed Alsafran, Muhammad Rizwan, Kamal Usman, Muhammad Hamzah Saleem, Hareb Al Jabri
Summary: This paper reviews the distribution, exposure risk, and potential toxic effects of neonicotinoid insecticides (NENIs) in the environment and food chain. It highlights the substantial risks posed by these insecticides to the environment, humans, and non-target species. The review calls for global multidisciplinary research efforts to fill the existing knowledge gaps and further investigate the toxic effects of NENIs on the ecosystem.
JOURNAL OF ENVIRONMENTAL CHEMICAL ENGINEERING
(2022)
Review
Environmental Sciences
Klaudia Swiacka, Alicja Michnowska, Jakub Maculewicz, Magda Caban, Katarzyna Smolarz
Summary: Research on the impact of NSAIDs on aquatic animals highlights the importance of understanding the effects on the overall aquatic environment and the areas where further analysis is needed.
ENVIRONMENTAL POLLUTION
(2021)
Review
Chemistry, Applied
Beatriz del Rio, Maria Fernandez, Begona Redruello, Victor Ladero, Miguel A. Alvarez
Summary: Biogenic amines (BA) are molecules with biological functions that can accumulate at toxic concentrations in foods. Some microorganisms have been identified as responsible for their accumulation. Histamine, tyramine, and putrescine are the most commonly found BA at highest concentrations. Ingesting food with high BA concentrations can lead to intoxication. Additionally, there is synergy between different BA, emphasizing the need for regulation to protect consumer health.
Review
Environmental Sciences
Dandan Gao, Xinyu Liu, Muhammad Junaid, Hongping Liao, Guanglong Chen, Yan Wu, Jun Wang
Summary: This article focuses on the toxic effects of micro(nano)plastics (MNPs) on benthic organisms, summarizing the accumulation of MNPs in benthic organisms and the resulting tissue damage, genotoxicity, and reproductive toxicity. The complexity of co-exposure to MNPs with other aquatic contaminants is highlighted, and the internal and external factors affecting the toxicity of MNPs in benthic organisms are discussed. Overall, this study provides important background information for a thorough understanding of the toxic effects of MNPs in the benthic aquatic ecosystem.
SCIENCE OF THE TOTAL ENVIRONMENT
(2022)
Article
Environmental Sciences
Julieta Peluso, Agostina Martinez Chehda, Melisa S. Olivelli, Federico M. Ivanic, Cristina S. Perez-Coll, Florencia Gonzalez, Lautaro Valenzuela, Dante Rojas, Diego Cristos, Matias Butler, Roberto J. Candal, Carolina M. Aronzon
Summary: This study aimed to analyze the impacts of cattle breeding and agricultural activities on a stream in the Paran ' a River lower basin in Argentina. The results showed a degradation in water quality at all sites due to the presence of pollutants such as metals, pesticides, and emerging contaminants. The study also found that the surrounding agricultural and cattle breeding activities significantly affected the health and survival of the native amphibian species present in the stream.
ENVIRONMENTAL RESEARCH
(2023)
Article
Chemistry, Physical
Hira Fatima, Muhammad Rizwan Azhar, Chencheng Cao, Zongping Shao
Summary: This study investigated the photocatalytic degradation of conventional and emerging pollutants using core-shell zinc doped hexacyanoferrate@Prussian blue nanoparticles under light irradiation. Different synthesis parameters were studied, and the optimized photocatalyst degraded 94% of methylene blue within 24 minutes. The nanoparticles also showed potential for the photodegradation of parabens in municipal wastewater. The results suggest that these nanoparticles can be used for effective photocatalytic remediation of various pollutants.
JOURNAL OF COLLOID AND INTERFACE SCIENCE
(2023)
Article
Environmental Sciences
Mercedes Lourido, Julieta Peluso, Carolina M. Aronzon
Summary: The presence of oxytetracycline in the environment has negative effects on the embryos and larvae of Rhinella arenarum, primarily through oxidative stress and neurotoxicity.
ENVIRONMENTAL TOXICOLOGY AND PHARMACOLOGY
(2022)
Review
Food Science & Technology
Mohsen Gavahian, Girish N. Mathad, Carlos A. F. Oliveira, Amin Mousavi Khaneghah
Summary: Consumption of foods containing mycotoxins can pose significant health risks, and strategies to reduce mycotoxins include prevention of contamination by toxigenic fungi and detoxifying techniques. This study explores the potential of using emerging technologies in combination with fermentation to degrade mycotoxins in foods through interactive effects.
FOOD RESEARCH INTERNATIONAL
(2021)
Article
Engineering, Environmental
Maria J. Martin de Vidales, Esteban Palomo de la Fuente, Evangelina Atanes-Sanchez, Francisco Fernandez-Martinez
Summary: The aim of this study was to develop a new, highly compact multi-option photo reactor for the removal of emerging contaminants from wastewater. Different advanced oxidation processes, including electrochemical oxidation, photolysis, and photocatalysis with TiO2 nanotubes array, were investigated and combined to create a photoelectrocatalytic oxidation process. The efficiency of these processes was evaluated by measuring the removal of ofloxacin, a pharmaceutical compound used as a model contaminant. SEM and XRD characterization confirmed the formation of anatase-phase nanotubes with suitable dimensions for photocatalytic reactions. The results demonstrated that the coupling of these technologies was effective, leading to high process efficiencies.
JOURNAL OF ENVIRONMENTAL CHEMICAL ENGINEERING
(2022)
Review
Green & Sustainable Science & Technology
Li-Juan Zhang, Lu Qian, Ling-Yun Ding, Lei Wang, Ming Hung Wong, Hu-Chun Tao
Summary: This review discusses the application of metabolomics in analyzing the metabolic responses of environmental organisms to various anthropogenic contaminants, as well as evaluating their ecotoxicological impacts. It reveals both the effects of contaminants on metabolism in organisms and the regulation of metabolic pathways, providing insights into how anthropogenic contaminants influence specific metabolic pathways in living organisms through global metabolism variations. The study demonstrates the potential for risk assessments of anthropogenic contaminants using environmental metabolomics.
ENVIRONMENTAL SCIENCE AND ECOTECHNOLOGY
(2021)
Review
Environmental Sciences
Mengfan Liao, Songyi Wei, Jinru Zhao, Jun Wang, Guangquan Fan
Summary: The increased use of disinfection products during the COVID-19 pandemic has led to a rise in environmental contamination by disinfectants, which is considered a major global concern. This review focuses on the occurrence, bioaccumulation, and potential environmental risks of benzalkonium chlorides (BKCs) as emerging contaminants. The study found that BKCs were present in various environmental samples across 13 countries, including municipal wastewater, surface water, groundwater, reclaimed water, and sediment. The high levels of BKCs in water and solid environmental samples pose potential adverse effects on aquatic and terrestrial species, and may even bioaccumulate in plants and humans. Additionally, the residual BKCs in the environment can disrupt microbial balance and induce resistance. Taking lessons from the management of pharmaceutical emerging contaminants, the review suggests using the approach of ecopharmacovigilance (EPV) to address the environmental risks posed by disinfectant emerging contaminants.
ECOTOXICOLOGY AND ENVIRONMENTAL SAFETY
(2023)
Review
Environmental Sciences
Eduarda Roberta Bordin, Wanessa Algarte Ramsdorf, Luana Maria Lotti Domingos, Luis Phelipe de Souza Miranda, Ney Pereira Mattoso, Marta Margarete Cestari
Summary: The rapid development of nanotechnology has led to the release of various products without fully understanding their potential impact on the environment. This study focuses on the effects of zinc oxide nanoparticles (ZnO-NPs) on non-target organisms, aiming to ensure human health and environmental safety. A systematic review of available data on the toxicity of ZnO-NPs to freshwater and marine/estuarine aquatic organisms was conducted. The findings suggest that freshwater invertebrates are the most commonly used organisms in ecotoxicological tests. The primary mechanisms of ZnO-NPs toxicity involve the release of Zn2+ ions and the generation of reactive oxygen species (ROS).
JOURNAL OF ENVIRONMENTAL MANAGEMENT
(2024)
Article
Chemistry, Analytical
Goncalo Pedro, Frederico Duarte, Dmitrii A. Cheptsov, Nikita Yu. Volodin, Ivan V. Ivanov, Hugo M. Santos, Jose Luis Capelo-Martinez, Cristian Cuerva, Elisabete Oliveira, Valerii F. Traven, Carlos Lodeiro
Summary: Three coumarin-based boron complexes (L1, L2 and L3) were successfully incorporated into polymeric matrixes for temperature probes, showing high fluorescence quantum yield in solution and positive solvatochromism. L1 exhibited a colour change and quenching in emission intensity in the presence of anions due to deprotonation. The dye@doped polymers of L1, L2 and L3 showed excellent fluorescent response and reversibility as temperature sensors.
Article
Biochemistry & Molecular Biology
Goncalo A. Marcelo, David Montpeyo, Joana Galhano, Ramon Martinez-Manez, Jose Luis Capelo-Martinez, Julia Lorenzo, Carlos Lodeiro, Elisabete Oliveira
Summary: In this study, a combinatory antitumoral nanotherapy was developed using magneto-fluorescent nanoparticles as carriers for a combination of two drugs (doxorubicin and ofloxacin) and surface modification with two targeting agents (AZM-SH and Cetuximab). The results showed that the nanoparticles modified with AZM-SH had higher cellular uptake than those modified with Cetuximab, making them more effective for colorectal cancer cells. Furthermore, the oral administration of the nanoparticles with an enteric coating was successfully achieved under extreme conditions.
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
(2023)
Article
Biochemical Research Methods
Luis B. Carvalho, Jose Luis Capelo Martinez, Carlos Lodeiro, Rafael Bento, Rajiv Dhir, Jeremiah J. Morrissey, Luis Campos Pinheiro, Mariana Medeiros, Hugo M. Santos
Summary: Urinary proteomics can predict bladder cancer recurrence and identify dysregulation of inflammation and immune systems as key drivers of disease worsening. Proteomics can be used to monitor the effectiveness of therapy in the inflammatory and immune systems.
JOURNAL OF PROTEOMICS
(2023)
Review
Chemistry, Analytical
Hugo M. Santos, Luis B. Carvalho, Carlos Lodeiro, Goncalo Martins, Ines L. Gomes, Wilson D. T. Antunes, Vanessa Correia, Maria M. Almeida-Santos, Helena Rebelo-de-Andrade, Antonio P. A. Matos, J. L. Capelo
Summary: This work presents a tutorial on the capabilities of bioanalytical mass spectrometry in detecting and differentiating viruses at the peptide level, as well as providing diagnosis and prognosis for infected patients. It offers insights into the possibilities of current high-resolution mass spectrometry technology and bioinformatics.
MICROCHEMICAL JOURNAL
(2023)
Article
Chemistry, Applied
Frederico Duarte, Georgi Dobrikov, Atanas Kurutos, Hugo M. Santos, Javier Fernandez-Lodeiro, Jose Luis Capelo-Martinez, Elisabete Oliveira, Carlos Lodeiro
Summary: Polarity-sensitive dansyl derivatives L1 and L2 were synthesized and their ability to sense pollutant metal ions was investigated. Both L1 and L2 exhibited high sensitivity towards Cu2+ and Hg2+ metal ions, with L2 capable of detecting and quantifying Hg2+ concentrations as low as 2.5 μM. Additionally, both compounds showed positive sol-vatofluorochromic behavior, modulated in the presence of water, leading to fluorescence enhancement through aggregation-induced emission (AIE). Luminescent L1-based polystyrene-block-polybutadiene-block-polystyrene (SBS) microparticles were successfully prepared, demonstrating the potential applications of dansyl-derivatives in biomedicine and environmental fields.
Article
Chemistry, Applied
Carlos Lodeiro, Jose Luis Capelo-Martinez
Summary: The ICEM-E-3 series of conferences, which started in 2014 in Costa de Caparica, Portugal, focuses on the continuous improvements in synthetic methods and applications of dyes and pigments. The 5th edition of the conference in July 2022 highlighted the importance of organic dyes, inorganic complexes, solar cells materials, solar concentrators, sensors, new dyes and colorants, nanomaterials, and organic&inorganic hybrid colored materials in industrial and technological advances.
Article
Chemistry, Physical
Carlos Martinez-Ceberio, M. Carmen Torralba, Frederico Duarte, Santiago Herrero, Mercedes Cano, Carlos Lodeiro, Cristian Cuerva
Summary: Two new families of compounds with mesomorphic and luminescent behaviors were obtained using pyridine-functionalized fl-diketones as building blocks. The coordination of the fl-diketones to metal centers allowed the synthesis of neutral coordination compounds and cationic species. Protonation of the pyridine moiety yielded a novel series of pyridinium ionic salts. The nature of the complexes, fl-diketone ligands, and metal center greatly influenced the mesomorphic behavior and luminescence properties.
JOURNAL OF MOLECULAR LIQUIDS
(2023)
Article
Chemistry, Physical
Frederico Duarte, Georgi Dobrikov, Atanas Kurutos, Jose Luis Capelo-Martinez, Hugo M. Santos, Elisabete Oliveira, Carlos Lodeiro
Summary: Three novel bis-dansyl derivatives with a sulfur bridge were synthesized and their photophysical properties were studied in solution and in the solid state. The compounds exhibited fluorescence emission with quantum yields up to 60%, which depended on the solvent and molecular structure. Positive solvatofluorochromic behavior was observed, with emission ranging from bluish-green to yellow. The compounds showed high sensitivity to Cu2+ and Hg2+ ions, and one compound (L2) could detect and quantify up to 4 μM of Hg2+. Polymer thin films were fabricated to establish a linear relationship between emission and temperature, suggesting the potential application of these compounds as molecular thermometers.
JOURNAL OF PHOTOCHEMISTRY AND PHOTOBIOLOGY A-CHEMISTRY
(2023)
Article
Chemistry, Physical
Silvia Nuti, Adriaïn Fernandez-Lodeiro, Lidia E. Chinchilla, Ana B. Hungria, Jose-Luis Capelo-Martinez, Carlos Lodeiro, Javier Fernandez-Lodeiro
Summary: This study presents a simple method for fabricating Au@Pd bimetallic branched nanoparticles, which allow for tunable optical response, using polyallylamine-stabilized branched AuNPs as template cores for Pd overgrowth. The concentration of PdCl4(2-) and ascorbic acid (AA) can be manipulated to alter the palladium content, enabling the growth of a Pd shell up to approximately 2 nm thick. The presence of palladium on the surface of gold nanoparticles enhances their catalytic properties, as demonstrated through a comparison of nanoenzymatic activity.
JOURNAL OF PHYSICAL CHEMISTRY LETTERS
(2023)
Article
Chemistry, Multidisciplinary
Carlos Fernandez-Lodeiro, Reem Tambosi, Javier Fernandez-Lodeiro, Adrian Fernandez-Lodeiro, Silvia Nuti, Soufian Ouchane, Nouari Kebaili, Jorge Perez-Juste, Isabel Pastoriza-Santos, Carlos Lodeiro
Summary: In this study, a novel approach for silica coating of silver nanoparticles using adenosine monophosphate (AMP) surface modification was proposed. The thickness of the silica coating could be tightly adjusted by varying the silica precursor or CTAC concentration. The study also revealed the influence of silica coating on the antimicrobial effect of AgNPs and investigated different bacterial growth conditions.
Article
Chemistry, Multidisciplinary
Adrian Fernandez-Lodeiro, Javier Fernandez Lodeiro, Noelia Losada-Garcia, Silvia Nuti, Jose Luis Capelo-Martinez, Jose M. M. Palomo, Carlos Lodeiro
Summary: This study investigates the potential utilization of Cu(i) as a reducing agent to transform K2PtCl4 into stable nanoparticles. The synthesized nanoparticles have a bimetallic composition with copper. This approach offers a convenient and accessible method for producing bimetallic nanostructures. The catalytic properties of these nanomaterials have been explored in various applications, showing the significant potential of Cu(i)-mediated reduction in developing functional nanomaterials.
NANOSCALE ADVANCES
(2023)
Article
Medicine, Research & Experimental
Luis Botelho Carvalho, Jose Luis Capelo, Carlos Lodeiro, Rajiv Dhir, Luis Campos Pinheiro, Hugo Lopez-Fernandez, Goncalo Martins, Mariana Medeiros, Fernando Diaz, Hugo Miguel Santos
Summary: This study demonstrates a method for longitudinally monitoring the disease course in bladder cancer patients using urine proteomic analysis and the differential personal pathway index (dPPi) calculation, over a period of 62 months. The dPPi reflects the individual's course of bladder cancer and helps optimize the use of more invasive procedures such as cystoscopy.
COMMUNICATIONS MEDICINE
(2023)
Article
Biochemical Research Methods
Luis B. Carvalho, Susana Jorge, Hugo Lopez-Fernandez, Carlos Lodeiro, Rajiv Dhir, Luis Campos Pinheiro, Mariana Medeiros, Hugo M. Santos, Jose L. Capelo
Summary: This study explored the proteomic landscapes of chRCC and RO and found significant similarities in dysregulated metabolic pathways, as well as a distinct divergence in the oxidative phosphorylation pathway, with RO showing more alterations.
CLINICAL PROTEOMICS
(2023)
