Modulation of cell viability, oxidative stress, calcium homeostasis, and voltage- and ligand-gated ion channels as common mechanisms of action of (mixtures of) non-dioxin-like polychlorinated biphenyls and polybrominated diphenyl ethers

The Role of Calcium Stores in Apoptosis and Autophagy

(2013) S. S. Smaili et al.   CURRENT MOLECULAR MEDICINE

Blood levels of dioxins, furans, dioxin-like PCBs, and TEQs in general populations: A review, 1989–2010

(2012) Dario Consonni et al.   ENVIRONMENT INTERNATIONAL

Subchronic Inhalation Exposure Study of an Airborne Polychlorinated Biphenyl Mixture Resembling the Chicago Ambient Air Congener Profile

(2012) Xin Hu et al.   ENVIRONMENTAL SCIENCE & TECHNOLOGY

Multiple Novel Modes of Action Involved in the In Vitro Neurotoxic Effects of Tetrabromobisphenol-A

(2012) Hester S. Hendriks et al.   TOXICOLOGICAL SCIENCES

Differential Effects of 20 Non-Dioxin-Like PCBs on Basal and Depolarization-Evoked Intracellular Calcium Levels in PC12 Cells

(2012) W. T. Langeveld et al.   TOXICOLOGICAL SCIENCES

Hydroxylated PBDEs induce developmental arrest in zebrafish

(2012) Crystal Y. Usenko et al.   TOXICOLOGY AND APPLIED PHARMACOLOGY

Modulation of human α4β2 nicotinic acetylcholine receptors by brominated and halogen-free flame retardants as a measure for in vitro neurotoxicity

(2012) Hester S. Hendriks et al.   TOXICOLOGY LETTERS

Neurotoxicity of Brominated Flame Retardants: (In)direct Effects of Parent and Hydroxylated Polybrominated Diphenyl Ethers on the (Developing) Nervous System

(2011) Milou M.L. Dingemans et al.   ENVIRONMENTAL HEALTH PERSPECTIVES

Genotoxicity of Several Polybrominated Diphenyl Ethers (PBDEs) and Hydroxylated PBDEs, and Their Mechanisms of Toxicity

(2011) Kyunghee Ji et al.   ENVIRONMENTAL SCIENCE & TECHNOLOGY

Caveats and limitations of plate reader-based high-throughput kinetic measurements of intracellular calcium levels

(2011) Harm J. Heusinkveld et al.   TOXICOLOGY AND APPLIED PHARMACOLOGY

Effects of non-dioxin-like polychlorinated biphenyl congeners (PCB 101, PCB 153 and PCB 180) alone or mixed on J774A.1 macrophage cell line: modification of apoptotic pathway

(2011) M.C. Ferrante et al.   TOXICOLOGY LETTERS

Polychlorinated Biphenyls PCB 52, PCB 180, and PCB 138 Impair the Glutamate−Nitric Oxide−cGMP Pathway in Cerebellar Neurons in Culture by Different Mechanisms

(2010) Marta Llansola et al.   CHEMICAL RESEARCH IN TOXICOLOGY

Prenatal Exposure to PBDEs and Neurodevelopment

(2010) Julie B. Herbstman et al.   ENVIRONMENTAL HEALTH PERSPECTIVES

Para- and Ortho -Substitutions Are Key Determinants of Polybrominated Diphenyl Ether Activity toward Ryanodine Receptors and Neurotoxicity

(2010) Kyung Ho Kim et al.   ENVIRONMENTAL HEALTH PERSPECTIVES

The cytotoxic effects of synthetic 6-hydroxylated and 6-methoxylated polybrominated diphenyl ether 47 (BDE47)

(2010) Jing An et al.   ENVIRONMENTAL TOXICOLOGY

Developmental exposure to polychlorinated biphenyls 52, 138 or 180 affects differentially learning or motor coordination in adult rats. mechanisms involved

(2010) J. Boix et al.   NEUROSCIENCE

Hippocampal Neurons Exposed to the Environmental Contaminants Methylmercury and Polychlorinated Biphenyls Undergo Cell Death via Parallel Activation of Calpains and Lysosomal Proteases

(2010) Roshan Tofighi et al.   NEUROTOXICITY RESEARCH

Calcium-Related Processes Involved in the Inhibition of Depolarization-Evoked Calcium Increase by Hydroxylated PBDEs in PC12 Cells

(2010) Milou M. L. Dingemans et al.   TOXICOLOGICAL SCIENCES

Cell Death Mechanisms and Their Implications in Toxicology

(2010) Sten Orrenius et al.   TOXICOLOGICAL SCIENCES

Activation and Potentiation of Human GABAA Receptors by Non-Dioxin–Like PCBs Depends on Chlorination Pattern

(2010) Elsa C. Antunes Fernandes et al.   TOXICOLOGICAL SCIENCES

PCB-47, PBDE-47, and 6-OH-PBDE-47 Differentially Modulate Human GABAA and α4β2 Nicotinic Acetylcholine Receptors

(2010) Hester S. Hendriks et al.   TOXICOLOGICAL SCIENCES

Changes in mitogen-activated protein kinase in cerebellar granule neurons by polybrominated diphenyl ethers and polychlorinated biphenyls☆☆☆

(2010) Chun-Yang Fan et al.   TOXICOLOGY AND APPLIED PHARMACOLOGY

The complexity of the GABAA receptor shapes unique pharmacological profiles

(2009) Charlotte D’Hulst et al.   DRUG DISCOVERY TODAY

Prenatal Exposure to Organohalogens, Including Brominated Flame Retardants, Influences Motor, Cognitive, and Behavioral Performance at School Age

(2009) Elise Roze et al.   ENVIRONMENTAL HEALTH PERSPECTIVES

Serum Polybrominated Diphenyl Ether (PBDE) Levels Are Higher in Children (2–5 Years of Age) than in Infants and Adults

(2009) Leisa-Maree L. Toms et al.   ENVIRONMENTAL HEALTH PERSPECTIVES

Bromination Pattern of Hydroxylated Metabolites of BDE-47 Affects Their Potency to Release Calcium from Intracellular Stores in PC12 Cells

(2009) Milou M.L. Dingemans et al.   ENVIRONMENTAL HEALTH PERSPECTIVES

Potentiation of the Human GABAAReceptor As a Novel Mode of Action of Lower-Chlorinated Non-Dioxin-Like PCBs†

(2009) Elsa C. Antunes Fernandes et al.   ENVIRONMENTAL SCIENCE & TECHNOLOGY

Effects of decabrominated diphenyl ether (PBDE 209) on voltage-gated sodium channels in primary cultured rat hippocampal neurons

(2009) Tai-Ran Xing et al.   ENVIRONMENTAL TOXICOLOGY

Cytogenotoxicity induced by PBDE-47 combined with PCB153 treatment in SH-SY5Y cells

(2009) Weihong He et al.   ENVIRONMENTAL TOXICOLOGY

Hydroxylated PCB induces Ca2+oscillations and alterations of membrane potential in cultured cortical cells

(2009) Marina Londoño et al.   JOURNAL OF APPLIED TOXICOLOGY

Mechanisms involved in the neurotoxic effects of environmental toxicants such as polychlorinated biphenyls and brominated flame retardants

(2009) Frode Fonnum et al.   JOURNAL OF NEUROCHEMISTRY

The dynamic effects of nicotine on the developing brain

(2009) Jennifer B. Dwyer et al.   PHARMACOLOGY & THERAPEUTICS

Minding the calcium store: Ryanodine receptor activation as a convergent mechanism of PCB toxicity

(2009) Isaac N. Pessah et al.   PHARMACOLOGY & THERAPEUTICS

Comparative Cytotoxicity and Intracellular Accumulation of Five Polybrominated Diphenyl Ether Congeners in Mouse Cerebellar Granule Neurons

(2009) Suping C. Huang et al.   TOXICOLOGICAL SCIENCES

Effects of Decabrominated Diphenyl Ether (PBDE 209) Exposure at Different Developmental Periods on Synaptic Plasticity in the Dentate Gyrus of Adult Rats In Vivo

(2009) Tairan Xing et al.   TOXICOLOGICAL SCIENCES

Excitatory and inhibitory synaptic transmission is differentially influenced by two ortho-substituted polychlorinated biphenyls in the hippocampal slice preparation

(2009) Kyung Ho Kim et al.   TOXICOLOGY AND APPLIED PHARMACOLOGY

Hydroxylated polychlorinated biphenyls increase reactive oxygen species formation and induce cell death in cultured cerebellar granule cells

(2009) Anne Dreiem et al.   TOXICOLOGY AND APPLIED PHARMACOLOGY

Cell death mechanisms in GT1-7 GnRH cells exposed to polychlorinated biphenyls PCB74, PCB118, and PCB153

(2009) Sarah M. Dickerson et al.   TOXICOLOGY AND APPLIED PHARMACOLOGY

Low concentrations of the brominated flame retardants BDE-47 and BDE-99 induce synergistic oxidative stress-mediated neurotoxicity in human neuroblastoma cells

(2009) Sara Tagliaferri et al.   TOXICOLOGY IN VITRO

Levels and trends of HBCD and BDEs in the European and Asian environments, with some information for other BFRs

(2008) Robin J. Law et al.   CHEMOSPHERE

Hydroxylation Increases the Neurotoxic Potential of BDE-47 to Affect Exocytosis and Calcium Homeostasis in PC12 Cells

(2008) Milou M.L. Dingemans et al.   ENVIRONMENTAL HEALTH PERSPECTIVES

Human internal and external exposure to PBDEs – A review of levels and sources

(2008) Marie Frederiksen et al.   INTERNATIONAL JOURNAL OF HYGIENE AND ENVIRONMENTAL HEALTH

Calcium Channel Regulation and Presynaptic Plasticity

(2008) William A. Catterall et al.   NEURON

Neonatal exposure to deca-brominated diphenyl ether (PBDE 209) causes dose–response changes in spontaneous behaviour and cholinergic susceptibility in adult mice

(2008) N. Johansson et al.   NEUROTOXICOLOGY

Mechanism of the neurotoxic effect of PBDE-47 and interaction of PBDE-47 and PCB153 in enhancing toxicity in SH-SY5Y cells

(2008) Ping He et al.   NEUROTOXICOLOGY

Influence of PCB153 on Oxidative DNA Damage and DNA Repair–Related Gene Expression Induced by PBDE-47 in Human Neuroblastoma Cells In Vitro

(2008) Ping Gao et al.   TOXICOLOGICAL SCIENCES

DE-71-Induced Apoptosis Involving Intracellular Calcium and the Bax-Mitochondria-Caspase Protease Pathway in Human Neuroblastoma Cells In Vitro

(2008) Ke Yu et al.   TOXICOLOGICAL SCIENCES