Article
Environmental Sciences
Ulla Arthur Hvidtfeldt, Jie Chen, Zorana Jovanovic Andersen, Richard Atkinson, Mariska Bauwelinck, Tom Bellander, Jorgen Brandt, Bert Brunekreef, Giulia Cesaroni, Hans Concin, Daniela Fecht, Francesco Forastiere, Carla H. van Gils, John Gulliver, Ole Hertel, Gerard Hoek, Barbara Hoffmann, Kees de Hoogh, Nicole Janssen, Jeanette Therming Jorgensen, Klea Katsouyanni, Karl-Heinz Joeckel, Matthias Ketzel, Jochem O. Klompmaker, Alois Lang, Karin Leander, Shuo Liu, Petter L. S. Ljungman, Patrik K. E. Magnusson, Amar Jayant Mehta, Gabriele Nagel, Bente Oftedal, Goran Pershagen, Raphael Simon Peter, Annette Peters, Matteo Renzi, Debora Rizzuto, Sophia Rodopoulou, Evangelia Samoli, Per Everhard Schwarze, Gianluca Severi, Torben Sigsgaard, Massimo Stafoggia, Maciej Strak, Danielle Vienneau, Gudrun Weinmayr, Kathrin Wolf, Ole Raaschou-Nielsen
Summary: The study found a positive association between specific elemental components of PM2.5 and lung cancer incidence, with combustion particles from oil and biomass burning and secondary inorganic aerosols showing higher risk. Specific limit values or guidelines targeting these specific PM2.5 components may prove helpful in future lung cancer prevention strategies.
ENVIRONMENTAL RESEARCH
(2021)
Article
Oncology
Jie Chen, Sophia Rodopoulou, Maciej Strak, Kees de Hoogh, Tahir Taj, Aslak Harbo Poulsen, Zorana J. Andersen, Tom Bellander, Jorgen Brandt, Emanuel Zitt, Daniela Fecht, Francesco Forastiere, John Gulliver, Ole Hertel, Barbara Hoffmann, Ulla Arthur Hvidtfeldt, W. M. Monique Verschuren, Jeanette T. Jorgensen, Klea Katsouyanni, Matthias Ketzel, Anton Lager, Karin Leander, Shuo Liu, Petter Ljungman, Gianluca Severi, Marie-Christine Boutron-Ruault, Patrik K. E. Magnusson, Gabriele Nagel, Goran Pershagen, Annette Peters, Debora Rizzuto, Yvonne T. van der Schouw, Evangelia Samoli, Mette Sorensen, Massimo Stafoggia, Anne Tjonneland, Gudrun Weinmayr, Kathrin Wolf, Bert Brunekreef, Ole Raaschou-Nielsen, Gerard Hoek
Summary: This study found suggestive evidence of an association between long-term exposure to PM2.5 and bladder cancer, particularly with zinc in PM2.5. The findings strengthen the evidence from previous studies, indicating a potential impact of air pollution on bladder cancer incidence.
BRITISH JOURNAL OF CANCER
(2022)
Article
Cardiac & Cardiovascular Systems
Daniela Fecht, Marc Chadeau-Hyam, Ruth Owen, John Gregson, Brian P. Halliday, Amrit S. Lota, John Gulliver, James S. Ware, Dudley J. Pennell, Frank J. Kelly, Anoop S. V. Shah, Mark R. Miller, David E. Newby, Sanjay K. Prasad, Upasana Tayal
Summary: This study found that exposure to air pollution is associated with increased left ventricular mass and decreased left ventricular ejection fraction, with the strongest effect observed in women.
JOURNAL OF CARDIAC FAILURE
(2022)
Article
Critical Care Medicine
Shuo Liu, Youn-Hee Lim, Jie Chen, Maciek Strak, Kathrin Wolf, Gudrun Weinmayr, Sophia Rodopolou, Kees de Hoogh, Tom Bellander, Jorgen Brandt, Hans Concin, Emanuel Zitt, Daniela Fecht, Francesco Forastiere, John Gulliver, Ole Hertel, Barbara Hoffmann, Ulla A. Hvidtfeldt, W. M. Monique Verschuren, Karl-Heinz Joeckel, Jeanette T. Jorgensen, Rina So, Heresh Amini, Thomas Cole-Hunter, Amar J. Mehta, Laust H. Mortensen, Matthias Ketzel, Anton Lager, Karin Leander, Petter Ljungman, Gianluca Severi, Marie-Christine Boutron-Ruault, Patrik K. E. Magnusson, Gabriele Nagel, Goeran Pershagen, Annette Peters, Ole Raaschou-Nielsen, Debora Rizzuto, Yvonne T. van der Schouw, Sara Schramm, Mette Sorensen, Massimo Stafoggia, Anne Tjonneland, Klea Katsouyanni, Wei Huang, Evangelia Samoli, Bert Brunekreef, Gerard Hoek, Zorana J. Andersen
Summary: Long-term exposure to combustion-related air pollutants is associated with an increased risk of mortality from lower respiratory infections.
AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE
(2022)
Article
Environmental Sciences
Sasha Khomenko, Marta Cirach, Jose Barrera-Gomez, Evelise Pereira-Barboza, Tamara Iungman, Natalie Mueller, Maria Foraster, Cathryn Tonne, Meelan Thondoo, Calvin Jephcote, John Gulliver, James Woodcock, Mark Nieuwenhuijsen
Summary: This study aims to assess available data on road traffic noise in European cities and estimate the population's exposure and health impacts. The results show that many adults in European cities are exposed to road traffic noise levels that are harmful to health, with an increase in both high noise annoyance and Ischemic Heart Disease (IHD) mortality. Efforts to standardize noise maps and increase data availability are necessary for a more accurate assessment of health impacts and to address the adverse effects of road traffic noise at the local government level.
ENVIRONMENT INTERNATIONAL
(2022)
Article
Environmental Sciences
Anja H. Tremper, Calvin Jephcote, John Gulliver, Leon Hibbs, David C. Green, Anna Font, Max Priestman, Anna L. Hansell, Gary W. Fuller
Summary: There is limited understanding regarding the health impacts of aircraft noise and aircraft-associated ultrafine particles (UFP). Measurements conducted near Gatwick airport in the UK showed a close relationship between particle number concentrations (PNC) and noise levels, with traffic emissions being the major source of PNC. However, UFP is unlikely to be a significant factor in epidemiological studies on aircraft noise and health, as the correlation between UFP and noise is moderate to low. Additionally, meteorological factors should be taken into consideration when studying the short-term associations between aircraft noise and health.
ENVIRONMENT INTERNATIONAL
(2022)
Article
Environmental Sciences
Xiangpu Gong, Benjamin Fenech, Claire Blackmore, Yingxin Chen, Georgia Rodgers, John Gulliver, Anna L. Hansell
Summary: Most studies on noise and mental health have focused on noise exposure rather than noise annoyance. This systematic review and meta-analysis suggest a potential link between noise annoyance and mental health problems, including depression, anxiety, and general mental health.
INTERNATIONAL JOURNAL OF ENVIRONMENTAL RESEARCH AND PUBLIC HEALTH
(2022)
Article
Engineering, Environmental
Jie Chen, Gerard Hoek, Kees de Hoogh, Sophia Rodopoulou, Zorana J. Andersen, Tom Bellander, Jorgen Brandt, Daniela Fecht, Francesco Forastiere, John Gulliver, Ole Hertel, Barbara Hoffmann, Ulla Arthur Hvidtfeldt, W. M. Monique Verschuren, Karl-Heinz Joeckel, Jeanette T. Jorgensen, Klea Katsouyanni, Matthias Ketzel, Diego Yacaman Mendez, Karin Leander, Shuo Liu, Petter Ljungman, Elodie Faure, Patrik K. E. Magnusson, Gabriele Nagel, Goran Pershagen, Annette Peters, Ole Raaschou-Nielsen, Debora Rizzuto, Evangelia Samoli, Yvonne T. van der Schouw, Sara Schramm, Gianluca Severi, Massimo Stafoggia, Maciej Strak, Mette Sorensen, Anne Tjonneland, Gudrun Weinmayr, Kathrin Wolf, Emanuel Zitt, Bert Brunekreef, George D. Thurston
Summary: This study assessed the mortality risks associated with specific sources of fine particles (PM2.5) in a European cohort. The results showed that all identified sources of PM2.5 were significantly positively associated with increased natural mortality risks. Traffic, residual oil combustion, and biomass agriculture were found to have the strongest associations with mortality.
ENVIRONMENTAL SCIENCE & TECHNOLOGY
(2022)
Article
Oncology
Ulla Arthur Hvidtfeldt, Jie Chen, Sophia Rodopoulou, Maciej Strak, Kees de Hoogh, Zorana J. Andersen, Tom Bellander, Jorgen Brandt, Daniela Fecht, Francesco Forastiere, John Gulliver, Ole Hertel, Barbara H. Hoffmann, Klea Katsouyanni, Matthias Ketzel, Boel Brynedal, Karin Leander, Petter L. S. Ljungman, Patrik K. E. Magnusson, Gabriele Nagel, Goran Pershagen, Debora Rizzuto, Marie-Christine Boutron-Ruault, Evangelia Samoli, Rina So, Massimo Stafoggia, Anne Tjonneland, Roel Vermeulen, W. M. Monique Verschuren, Gudrun Weinmayr, Kathrin Wolf, Jiawei Zhang, Emanuel Zitt, Bert Brunekreef, Gerard Hoek, Ole Raaschou-Nielsen
Summary: This study examined the relationship between long-term air pollution exposure and breast cancer incidence. The results showed an association between PM2.5 and breast cancer, suggesting a potential role of exposure to NO2, PM2.5, and BC in the development of breast cancer.
CANCER EPIDEMIOLOGY BIOMARKERS & PREVENTION
(2023)
Article
Environmental Sciences
Calvin Jephcote, Sierra N. Clark, Anna L. Hansell, Nigel Jones, Yingxin Chen, Claire Blackmore, Katie Eminson, Megan Evans, Xiangpu Gong, Kathryn Adams, Georgia Rodgers, Benjamin Fenech, John Gulliver
Summary: This study provides a novel assessment of the health impacts of transportation noise in England and highlights the significant burden of sleep disturbance, ischemic heart disease, stroke, and diabetes caused by noise pollution. London, the South East, and North West regions bear the heaviest disease burden, particularly from road traffic noise. The study emphasizes the importance of addressing transportation noise for public health and provides valuable insights for policy-making.
ENVIRONMENT INTERNATIONAL
(2023)
Article
Environmental Sciences
Kelly Chen, Jochem O. Klompmaker, Charlotte J. Roscoe, Long H. Nguyen, David A. Drew, Peter James, Francine Laden, Daniela Fecht, Weiyi Wang, John Gulliver, Jonathan Wolf, Claire J. Steves, Tim D. Spector, Andy T. Chan, Jaime E. Hart
Summary: A study found that living in neighborhoods with more green spaces may be associated with a lower risk of COVID-19-like illness, but this association is not observed in all populations.
ENVIRONMENTAL EPIDEMIOLOGY
(2023)
Article
Oncology
Ulla Arthur Hvidtfeldt, Jie Chen, Sophia Rodopoulou, Maciej Strak, Kees de Hoogh, Zorana J. Andersen, Tom Bellander, Jorgen Brandt, Daniela Fecht, Francesco Forastiere, John Gulliver, Ole Hertel, Barbara Hoffmann, Klea Katsouyanni, Matthias Ketzel, Karin Leander, Patrik K. E. Magnusson, Gabriele Nagel, Goeran Pershagen, Debora Rizzuto, Evangelia Samoli, Rina So, Massimo Stafoggia, Anne Tjonneland, Gudrun Weinmayr, Kathrin Wolf, Jiawei Zhang, Emanuel Zitt, Bert Brunekreef, Gerard Hoek, Ole Raaschou-Nielsen
Summary: This study examined the association between residential exposure to nitrogen dioxide (NO2), fine particles (PM2.5), black carbon (BC), ozone (O3), and eight elemental components of PM2.5 and malignant tumours of the central nervous system (CNS). The results indicated a potential association between NO2, PM2.5, and BC exposure and CNS tumours, while the PM elements did not show consistent association with tumour incidence.
BRITISH JOURNAL OF CANCER
(2023)
Article
Environmental Sciences
Nicole Itzkowitz, Xiangpu Gong, Glory Atilola, Garyfallos Konstantinoudis, Kathryn Adams, Calvin Jephcote, John Gulliver, Anna L. Hansell, Marta Blangiardo
Summary: Aircraft noise has short-term associations with cardiovascular events, particularly during the previous evening and early morning hours. Factors such as age-sex, ethnicity, deprivation, and season can modify these effects. High noise variability at night may be associated with higher risks. The mechanisms behind these associations include sleep disturbance, increased blood pressure and stress hormone levels, and impaired endothelial function.
ENVIRONMENT INTERNATIONAL
(2023)
Article
Environmental Sciences
Irene van Kamp, Kerstin Persson Waye, Katja Kanninen, John Gulliver, Alessandro Bozzon, Achilleas Psyllidis, Hendriek Boshuizen, Jenny Selander, Peter van den Hazel, Marco Brambilla, Maria Foraster, Jordi Julvez, Maria Klatte, Sonja Jeram, Peter Lercher, Dick Botteldooren, Gordana Ristovska, Jaakko Kaprio, Dirk Schreckenberg, Maarten Hornikx, Janina Fels, Miriam Weber, Ella Braat-Eggen, Julia Hartmann, Charlotte Clark, Tanja Vrijkotte, Lex Brown, Gabriele Bolte
Summary: The Equal-Life project aims to study the impact of combined exposures on children's mental health and cognitive development, by integrating different aspects of the child's environment and looking at supportive environments for child development. The project utilizes a variety of data sources, including GIS-based environmental indicators and omics approaches, to form a comprehensive early-life exposome. Through statistical analysis and machine learning models, Equal-Life seeks to provide insights into the effects of physical and social exposures on children's development over time.
ENVIRONMENTAL EPIDEMIOLOGY
(2022)
Article
Environmental Sciences
Massimo Stafoggia, Bente Oftedal, Jie Chen, Sophia Rodopoulou, Matteo Renzi, Richard W. Atkinson, Mariska Bauwelinck, Jochem O. Klompmaker, Amar Mehta, Danielle Vienneau, Zorana J. Andersen, Tom Bellander, Jorgen Brandt, Giulia Cesaroni, Kees de Hoogh, Daniela Fecht, John Gulliver, Ole Hertel, Barbara Hoffmann, Ulla A. Hvidtfeldt, Karl-Heinz Joeckel, Jeanette T. Jorgensen, Klea Katsouyanni, Matthias Ketzel, Doris Tove Kristoffersen, Anton Lager, Karin Leander, Shuo Liu, Petter L. S. Ljungman, Gabriele Nagel, Goran Pershagen, Annette Peters, Ole Raaschou-Nielsen, Debora Rizzuto, Sara Schramm, Per E. Schwarze, Gianluca Severi, Torben Sigsgaard, Maciek Strak, Yvonne T. van der Schouw, Monique Verschuren, Gudrun Weinmayr, Kathrin Wolf, Emanuel Zitt, Evangelia Samoli, Francesco Forastiere, Bert Brunekreef, Gerard Hoek, Nicole A. H. Janssen
Summary: This study analyzed the associations between low-level air pollution and mortality in seven large European cohorts, finding significant positive associations between non-accidental mortality and PM2.5, NO2, and black carbon. The associations were slightly weaker for cardiovascular mortality, similar for non-malignant respiratory mortality, and stronger for lung cancer mortality. Warm-season ozone was negatively associated with both non-accidental and cause-specific mortality. The study highlights the importance of considering low concentrations of air pollutants in setting air quality standards.
LANCET PLANETARY HEALTH
(2022)