Article
Medicine, General & Internal
Yan Wang, Huijuan Li, Juan Wang, Wei Zhao, Zhipeng Zeng, Li Hao, Yifang Yuan, Yuwei Lin, Yangfeng Wu, Zhengzhen Wang
Summary: This study aimed to establish normal reference values of peak oxygen uptake (VO2peak) for cardiorespiratory fitness (CRF) in Chinese adults using cardiorespiratory exercise testing (CPET). The results showed significant differences in VO2peak between men and women, with a decrease in VO2peak as age increased.
JOURNAL OF CLINICAL MEDICINE
(2022)
Article
Health Care Sciences & Services
Ori Hochwald, Lea Bentur, Yara Haddad, Moneera Hanna, Merav Zucker-Toledano, Gur Mainzer, Julie Haddad, Michal Gur, Liron Borenstein-Levin, Amir Kugelman, Ronen Bar-Yoseph
Summary: This study found that exercise capacity is lower in late preterm children compared to term children, but within the normal range, and comparable to that of early preterm children, with and without bronchopulmonary dysplasia (BPD). Lung function is only lower than normal in early preterm children.
JOURNAL OF PERSONALIZED MEDICINE
(2022)
Review
Rehabilitation
Eva Pella, Marieta P. Theodorakopoulou, Afroditi K. Boutou, Maria-Eleni Alexandrou, Dimitra-Rafailia Bakaloudi, Despoina Sarridou, Aristi Boulmpou, Christodoulos Papadopoulos, Aikaterini Papagianni, Pantelis Sarafidis
Summary: This systematic review and meta-analysis compares individuals with chronic kidney disease (CKD) to those without CKD using cardiopulmonary exercise testing (CPET). The study found that CKD patients have lower cardiopulmonary reserve compared to controls and perform better than controls with heart failure without CKD. The findings suggest the need for widespread application of rehabilitation programs for individuals with CKD.
ANNALS OF PHYSICAL AND REHABILITATION MEDICINE
(2022)
Review
Urology & Nephrology
Maria-Eleni Alexandrou, Marieta P. Theodorakopoulou, Afroditi Boutou, Eva Pella, Aristi Boulmpou, Christodoulos E. Papadopoulos, Andreas Zafeiridis, Aikaterini Papagianni, Pantelis Sarafidis
Summary: The peak oxygen uptake (VO(2)peak) and oxygen consumption at ventilatory threshold (VO2VT) were significantly lower in patients with CKD Stages 3b-5 compared to those with Stages 2-3a, indicating reduced cardiorespiratory fitness as a contributing factor to increased cardiovascular risk in advanced CKD stages.
Review
Medicine, General & Internal
Arianne Clare Agdamag, Erik H. H. Van Iterson, W. H. Wilson Tang, J. Emanuel Finet
Summary: Heart failure is a complex syndrome with diverse presentations and severity. Current prognostic markers, such as left ventricular ejection fraction, have limitations in accurately predicting outcomes and guiding management decisions. Metabolic exercise testing, which evaluates multisystem responses and aerobic capacity during exercise, provides a more comprehensive and reliable assessment, especially in heart failure patients.
JOURNAL OF CLINICAL MEDICINE
(2023)
Review
Hospitality, Leisure, Sport & Tourism
Yasmin Ezzatvar, Mikel Izquierdo, Julio Nunez, Joaquin Calatayud, Robinson Ramirez-Velez, Antonio Garcia-Hermoso
Summary: Cardiorespiratory fitness is inversely associated with mortality in patients with established cardiovascular disease, with each 1-MET increment significantly reducing all-cause mortality risk. Among coronary artery disease patients, high cardiorespiratory fitness is linked to a lower risk of all-cause mortality.
JOURNAL OF SPORT AND HEALTH SCIENCE
(2021)
Article
Cardiac & Cardiovascular Systems
Javier Roibal Pravio, Eduardo Barge Caballero, Cayetana Barbeito Caamano, Maria Jesus Paniagua Martin, Gonzalo Barge Caballero, David Couto Mallon, Patricia Pardo Martinez, Zulaika Grille Cancela, Paula Blanco Canosa, Jose Manuel Garcia Pinilla, Jose Manuel Vazquez Rodriguez, Maria Generosa Crespo Leiro
Summary: Maximum oxygen uptake (VO2max) is an important parameter in assessing the functional capacity of heart failure (HF) patients. Clinical factors such as NYHA class, age, body mass index, hemoglobin levels, and right ventricular function significantly influence exercise capacity in HF patients. The severity of HF and age, body composition, and hemoglobin levels can impact maximal oxygen uptake in HF patients.
Review
Medicine, General & Internal
Agnieszka Chwiedz, Lukasz Minarowski, Robert M. Mroz, Hady Razak Hady
Summary: This systematic review aims to describe the use of an inert gas rebreathing method for non-invasive cardiac output assessment during cardiopulmonary exercise testing and propose a CPET report that includes the assessment of cardiac output using this method. The review highlights the need for standardized approaches to CPET and identifies gaps in the current literature.
JOURNAL OF CLINICAL MEDICINE
(2023)
Review
Peripheral Vascular Disease
Myles N. Moore, Rachel E. Climie, Petr Otahal, Martin G. Schultz
Summary: The study found that exercise systolic blood pressure is associated with multiple cardiovascular risk factors, and individuals with a hypertensive response to exercise (HRE) exhibit worse cardiovascular risk factors compared to those with no-HRE. This relationship is consistent across different study populations.
JOURNAL OF HYPERTENSION
(2021)
Review
Hematology
Carlos Cruz-Montecinos, Rodrigo Nunez-Cortes, Luis Vasconcello-Castillo, Lilian Solis-Navarro, Bernardita Carrasco-Alonso, Joaquin Calatayud, Sofia Perez-Alenda, Rodrigo Torres-Castro
Summary: Research has found that individuals with haemophilia tend to have lower exercise capacity, highlighting the importance of promoting physical exercise in this population.
Review
Cardiac & Cardiovascular Systems
Yenny Villaseca-Rojas, Javiera Varela-Melo, Rodrigo Torres-Castro, Luis Vasconcello-Castillo, Guillermo Mazzucco, Jordi Vilaro, Isabel Blanco
Summary: Children and adolescents with congenital heart disease (CHD) have lower exercise capacity compared to healthy controls, as indicated by lower values of VO(2)peak, Wmax, VE/VCO2 slope, O-2 pulse, and HRmax. The reduction in exercise capacity is greater in adolescents.
FRONTIERS IN CARDIOVASCULAR MEDICINE
(2022)
Review
Cardiac & Cardiovascular Systems
Bibhuti B. Das
Summary: Cardiopulmonary exercise testing (CPET) is the clinical standard for evaluating children with congenital heart disease, heart failure candidates for transplantation, and those with unexplained dyspnea on exertion. It provides an integrated analysis of the multi-system response to exercise, aiding in differential diagnosis of exercise intolerance. This review discusses the interpretation and clinical significance of CPET results, focusing on cardiovascular diseases, and provides an algorithm for easy use in clinical practice.
JOURNAL OF CARDIOVASCULAR DEVELOPMENT AND DISEASE
(2023)
Article
Cardiac & Cardiovascular Systems
Martin Nicol, Antoine Deney, Olivier Lairez, Giuseppe Vergaro, Michele Emdin, Alessandro Carecci, Jocelyn Inamo, Astrid Montfort, Remi Neviere, Thibaud Damy, Stephanie Harel, Bruno Royer, Mathilde Baudet, Alain Cohen-Solal, Bertrand Arnulf, Damien Logeart
Summary: The study showed that cardiac involvement significantly worsens functional capacity and prognosis in patients with cardiac amyloidosis. Cardiopulmonary exercise testing (CPET) can be helpful in assessing functional capacity and risk stratification, alongside cardiac biomarkers, for patients with cardiac amyloidosis.
EUROPEAN JOURNAL OF HEART FAILURE
(2021)
Article
Cardiac & Cardiovascular Systems
Toshimi Sato, Shinichiro Morishita, Masahiro Ono, Yoshinari Funami, Keishi Hayao, Daichi Kusano, Masahiro Kohzuki
Summary: This study aimed to investigate the impact of exercise tolerance on renal function after acute myocardial infarction (AMI). The results showed that lower peak exercise oxygen uptake (VO2) levels were associated with a rapid decline in renal function. This suggests that poor exercise tolerance may be a risk factor for renal function deterioration after AMI.
Review
Cardiac & Cardiovascular Systems
Xiaohua Wan, Chang Liu, Thomas P. Olson, Xiankun Chen, Weihui Lu, Wei Jiang
Summary: The meta-analysis comparing peak oxygen uptake (VO2peak) between upright and supine lower extremity bicycle exercise revealed that VO2peak was higher in the upright position. The difference was more pronounced in healthy individuals compared to cardiopulmonary patients. Further research is needed to determine the clinical significance of this disparity.
FRONTIERS IN CARDIOVASCULAR MEDICINE
(2021)
Review
Rehabilitation
Aukje Andringa, Ingrid van de Port, Erwin van Wegen, Johannes Ket, Carel Meskers, Gert Kwakkel
ARCHIVES OF PHYSICAL MEDICINE AND REHABILITATION
(2019)
Article
Clinical Neurology
Rick van der Vliet, Ruud W. Selles, Eleni-Rosalina Andrinopoulou, Rinske Nijland, Gerard M. Ribbers, Maarten A. Frens, Carel Meskers, Gert Kwakkel
ANNALS OF NEUROLOGY
(2020)
Article
Neurosciences
Vincent Cox, Marijn Mulder, Rinske Nijland, Vera Schepers, Erwin Van Wegen, Caroline Van Heugten, Gert Kwakkel, Johanna Visser-Meily
Editorial Material
Clinical Neurology
Carel G. M. Meskers, Gert Kwakkel
DEVELOPMENTAL MEDICINE AND CHILD NEUROLOGY
(2020)
Editorial Material
Clinical Neurology
Gert Kwakkel, Bruce H. Dobkin
Article
Clinical Neurology
Marijn Mulder, Corien Nikamp, Rinske Nijland, Erwin van Wegen, Erik Prinsen, Judith Vloothuis, Jaap Buurke, Gert Kwakkel
Summary: The Armed4Stroke study aims to investigate the effects of a caregiver-mediated exercise program using a blended care approach in addition to usual care, on recovery of mobility in the first 6 months poststroke. The study includes a multicentre, observer-blinded randomized clinical trial with 74 patient-caregiver dyads, assessing self-reported mobility, care transition preparedness, psychological functioning, and other outcomes.
Article
Engineering, Biomedical
Mohamed Irfan Mohamed Refai, Mique Saes, Bouke L. Scheltinga, Joost van Kordelaar, Johannes B. J. Bussmann, Peter H. Veltink, Jaap H. Buurke, Carel G. M. Meskers, Erwin E. H. van Wegen, Gert Kwakkel, Bert-Jan F. Van Beijnum
Summary: This article conducted a systematic review and simulation analysis on smoothness metrics used in reaching tasks after stroke, and found that only Spectral Arc Length (SPARC) was identified as a valid metric for measuring smoothness in upper limb movements post-stroke.
JOURNAL OF NEUROENGINEERING AND REHABILITATION
(2021)
Editorial Material
Clinical Neurology
Beth Clark, Jill Whitall, Gert Kwakkel, Jan Mehrholz, Sean Ewings, Jane Burridge
Article
Clinical Neurology
Jeannette Hofmeijer, Florien Ham, Gert Kwakkel
Summary: Repetitive transcranial magnetic stimulation has the potential to improve motor and cognitive outcomes after stroke, but the evidence of efficacy is challenged by unexplained variability in small sampled trials. Future large trials should collect individual patient data and conduct sufficiently powered subgroup analyses, as well as protocolized time-locked training of target behavior.
Article
Clinical Neurology
Jonas Schroder, Wim Saeys, Elissa Embrechts, Ann Hallemans, Laetitia Yperzeele, Steven Truijen, Gert Kwakkel
Summary: This study investigates the recovery of quiet standing balance in stroke patients during the first 8 weeks poststroke and its association with lower limb motor recovery. The results show that postural stability improves significantly within the first 8 weeks poststroke and is independent of lower limb motor recovery.
NEUROREHABILITATION AND NEURAL REPAIR
(2023)
Article
Clinical Neurology
Aukje Andringa, Carel Meskers, Ingrid van de Port, Erwin van Wegen, Gert Kwakkel
NEUROREHABILITATION AND NEURAL REPAIR
(2020)
Article
Clinical Neurology
Sarah B. Zandvliet, Erwin E. H. van Wegen, S. Floor Campfens, Herman van der Kooij, Gert Kwakkel, Carel G. M. Meskers
NEUROREHABILITATION AND NEURAL REPAIR
(2020)
Proceedings Paper
Engineering, Biomedical
Mohamed Irian Mohamed Refai, Bert-Jan F. van Beijnum, Jaap H. Buurke, Mique Saes, Johannes B. J. Bussmann, Carel G. Meskers, Erwin van Wegen, Gert Kwakkel, Peter H. Veltink
2019 41ST ANNUAL INTERNATIONAL CONFERENCE OF THE IEEE ENGINEERING IN MEDICINE AND BIOLOGY SOCIETY (EMBC)
(2019)
Article
Rehabilitation
Nicotine M. Otterman, Marjo Maas, Sven K. Schiemanck, Philip van der Wees, Gert Kwakkel
JOURNAL OF REHABILITATION MEDICINE
(2019)
Article
Clinical Neurology
Sarah B. Zandvliet, Gert Kwakkel, Rinske H. M. Nijland, Erwin E. H. van Wegen, Carel G. M. Meskers
NEUROREHABILITATION AND NEURAL REPAIR
(2020)