Cross-Regulations among NRFs and KEAP1 and Effects of their Silencing on Arsenic-Induced Antioxidant Response and Cytotoxicity in Human Keratinocytes

Oncogene-induced Nrf2 transcription promotes ROS detoxification and tumorigenesis

(2011) Gina M. DeNicola et al.   NATURE

The Nrf2-Keap1-ARE Signaling Pathway: The Regulation and Dual Function of Nrf2 in Cancer

(2010) Donna D. Zhang   ANTIOXIDANTS & REDOX SIGNALING

Regulation of the Nrf2–Keap1 Antioxidant Response by the Ubiquitin Proteasome System: An Insight into Cullin-Ring Ubiquitin Ligases

(2010) Nicole F. Villeneuve et al.   ANTIOXIDANTS & REDOX SIGNALING

Low-Level Arsenic Impairs Glucose-Stimulated Insulin Secretion in Pancreatic Beta Cells: Involvement of Cellular Adaptive Response to Oxidative Stress

(2010) Jingqi Fu et al.   ENVIRONMENTAL HEALTH PERSPECTIVES

Long Isoforms of NRF1 Contribute to Arsenic-Induced Antioxidant Response in Human Keratinocytes

(2010) Rui Zhao et al.   ENVIRONMENTAL HEALTH PERSPECTIVES

Arsenic-Specific Stem Cell Selection During Malignant Transformation

(2010) Erik J. Tokar et al.   JNCI-Journal of the National Cancer Institute

Proteasomal Degradation Is Transcriptionally Controlled by TCF11 via an ERAD-Dependent Feedback Loop

(2010) Janos Steffen et al.   MOLECULAR CELL

The rise of antioxidant signaling—The evolution and hormetic actions of Nrf2

(2010) Jonathan Maher et al.   TOXICOLOGY AND APPLIED PHARMACOLOGY

Oncogenic NRF2 mutations in squamous cell carcinomas of oesophagus and skin

(2009) Yoo Ri Kim et al.   JOURNAL OF PATHOLOGY

Role of Nrf1 in antioxidant response element-mediated gene expression and beyond

(2009) Madhurima Biswas et al.   TOXICOLOGY AND APPLIED PHARMACOLOGY

Loss of Keap1 Function Activates Nrf2 and Provides Advantages for Lung Cancer Cell Growth

(2008) T. Ohta et al.   CANCER RESEARCH

Arsenic-induced malignant transformation of human keratinocytes: Involvement of Nrf2

(2008) Jingbo Pi et al.   FREE RADICAL BIOLOGY AND MEDICINE

Genetic Alteration of Keap1 Confers Constitutive Nrf2 Activation and Resistance to Chemotherapy in Gallbladder Cancer

(2008) Tatsuhiro Shibata et al.   GASTROENTEROLOGY

Activation of Nrf2-mediated oxidative stress response in macrophages by hypochlorous acid

(2007) Jingbo Pi et al.   TOXICOLOGY AND APPLIED PHARMACOLOGY