Genetic toxicology in the 21st century: Reflections and future directions

Impact of Environmental Chemicals on Key Transcription Regulators and Correlation to Toxicity End Points within EPA’s ToxCast Program

(2010) Matthew T. Martin et al.   CHEMICAL RESEARCH IN TOXICOLOGY

The Salmonella Mutagenicity Assay: The Stethoscope of Genetic Toxicology for the 21st Century

(2010) Larry D. Claxton et al.   ENVIRONMENTAL HEALTH PERSPECTIVES

An in Silico Method for Predicting Ames Activities of Primary Aromatic Amines by Calculating the Stabilities of Nitrenium Ions

(2010) Jörg Bentzien et al.   Journal of Chemical Information and Modeling

Characterizing and predicting carcinogenicity and mode of action using conventional and toxicogenomics methods

(2010) Michael D. Waters et al.   MUTATION RESEARCH-REVIEWS IN MUTATION RESEARCH

An update on the genotoxicity and carcinogenicity of marketed pharmaceuticals with reference to in silico predictivity

(2009) Ronald D. Snyder   ENVIRONMENTAL AND MOLECULAR MUTAGENESIS

In Vitro Screening of Environmental Chemicals for Targeted Testing Prioritization: The ToxCast Project

(2009) Richard S. Judson et al.   ENVIRONMENTAL HEALTH PERSPECTIVES

Mutagenicity testing for chemical risk assessment: update of the WHO/IPCS Harmonized Scheme

(2009) D. A. Eastmond et al.   MUTAGENESIS

Evaluation of high-throughput genotoxicity assays used in profiling the US EPA ToxCast™ chemicals

(2009) Andrew W. Knight et al.   REGULATORY TOXICOLOGY AND PHARMACOLOGY

Profiling the activity of environmental chemicals in prenatal developmental toxicity studies using the U.S. EPA's ToxRefDB

(2009) Thomas B. Knudsen et al.   REPRODUCTIVE TOXICOLOGY

Characterization and Interlaboratory Comparison of a Gene Expression Signature for Differentiating Genotoxic Mechanisms

(2009) Heidrun Ellinger-Ziegelbauer et al.   TOXICOLOGICAL SCIENCES

Profiling the Reproductive Toxicity of Chemicals from Multigeneration Studies in the Toxicity Reference Database

(2009) Matthew T. Martin et al.   TOXICOLOGICAL SCIENCES

Predicting the hepatocarcinogenic potential of alkenylbenzene flavoring agents using toxicogenomics and machine learning

(2009) Scott S. Auerbach et al.   TOXICOLOGY AND APPLIED PHARMACOLOGY

CCAN Makes Multiple Contacts with Centromeric DNA to Provide Distinct Pathways to the Outer Kinetochore

(2008) Tetsuya Hori et al.   CELL

The Toxicity Data Landscape for Environmental Chemicals

(2008) Richard Judson et al.   ENVIRONMENTAL HEALTH PERSPECTIVES

Profiling Chemicals Based on Chronic Toxicity Results from the U.S. EPA ToxRef Database

(2008) Matthew T. Martin et al.   ENVIRONMENTAL HEALTH PERSPECTIVES

Evaluation of the ability of a battery of three in vitro genotoxicity tests to discriminate rodent carcinogens and non-carcinogens

(2008) David Kirkland et al.   MUTATION RESEARCH-GENETIC TOXICOLOGY AND ENVIRONMENTAL MUTAGENESIS

Toxicity Testing in the 21st Century: Implications for Human Health Risk Assessment

(2008) Robert J. Kavlock et al.   RISK ANALYSIS

Transforming Environmental Health Protection

(2008) Francis S. Collins et al.   SCIENCE

Interlaboratory Evaluation of Genomic Signatures for Predicting Carcinogenicity in the Rat

(2008) Mark R. Fielden et al.   TOXICOLOGICAL SCIENCES

Application of toxicogenomics to study mechanisms of genotoxicity and carcinogenicity

(2008) Heidrun Ellinger-Ziegelbauer et al.   TOXICOLOGY LETTERS

Understanding Genetic Toxicity Through Data Mining: The Process of Building Knowledge by Integrating Multiple Genetic Toxicity Databases

(2008) C. Yang et al.   TOXICOLOGY MECHANISMS AND METHODS

Toxicity Data Informatics: Supporting a New Paradigm for Toxicity Prediction

(2008) Ann M. Richard et al.   TOXICOLOGY MECHANISMS AND METHODS

In Silico Screening of Chemicals for Genetic Toxicity Using MDL-QSAR, Nonparametric Discriminant Analysis, E-State, Connectivity, and Molecular Property Descriptors

(2008) Joseph F. Contrera et al.   TOXICOLOGY MECHANISMS AND METHODS

Combined Use of MC4PC, MDL-QSAR, BioEpisteme, Leadscope PDM, and Derek for Windows Software to Achieve High-Performance, High-Confidence, Mode of Action–Based Predictions of Chemical Carcinogenesis in Rodents

(2008) Edwin J. Matthews et al.   TOXICOLOGY MECHANISMS AND METHODS

Prediction of a carcinogenic potential of rat hepatocarcinogens using toxicogenomics analysis of short-term in vivo studies

(2007) Heidrun Ellinger-Ziegelbauer et al.   MUTATION RESEARCH-FUNDAMENTAL AND MOLECULAR MECHANISMS OF MUTAGENESIS