Article
Thermodynamics
Szymon Nosewicz, Grzegorz Jurczak, Tomasz Wejrzanowski, Samih Haj Ibrahim, Agnieszka Grabias, Witold Weglewski, Kamil Kaszyca, Jerzy Rojek, Marcin Chmielewski
Summary: This work presents a comprehensive analysis of heat transfer and thermal conductivity of porous materials manufactured by spark plasma sintering. The study includes experimental, theoretical, and numerical investigations. Microstructural characterization was extensively examined, and the experimental results were compared with theoretical and numerical ones. The Landauer relation was modified to take into account the thermal resistance of necks, resulting in satisfactory reconstruction of experimental results.
INTERNATIONAL JOURNAL OF HEAT AND MASS TRANSFER
(2022)
Article
Thermodynamics
Szymon Nosewicz, Grzegorz Jurczak, Tomasz Wejrzanowski, Samih Haj Ibrahim, Agnieszka Grabias, Witold Weglewski, Kamil Kaszyca, Jerzy Rojek, Marcin Chmielewski
Summary: This work comprehensively analyzes the heat transfer behavior and thermal conductivity of porous materials manufactured by spark plasma sintering. The study investigates the effects of different process parameters on material performance and characterizes the microstructure of the samples. It reveals the necessity of considering the additional thermal resistance caused by sintered necks and provides updated results for thermal conductivity evaluation, achieving good agreement with experimental data.
INTERNATIONAL JOURNAL OF HEAT AND MASS TRANSFER
(2022)
Article
Chemistry, Physical
M. Umer Ilyas, M. Rizviul Kabir
Summary: A study was conducted on the influence of the fully lamellar structure of TiAl alloys on creep behavior, proposing a crystal plasticity model with modified hardening behavior that explains how locally activated crystallographic deformation modes influence macroscopic creep behavior. Model validation showed accurate prediction of creep parameters under different temperature and stress loading conditions.
Article
Materials Science, Multidisciplinary
Spilios Dellis, Xiazi Xiao, Dmitry Terentyev, Efthymios Manios, Konstantina Mergia
Summary: The mechanical properties of cold rolled tungsten sheet after neutron irradiation at high temperature were studied using instrumented indentation and crystal plasticity finite element modeling (CPFEM). The load-depth curves of the indentation tests and microstructural information from transmission electron microscopy measurements were used to determine the contribution of irradiation damage in the constitutive laws. The simulated load-depth curves showed good agreement with experimental data and revealed that the hardness increase after irradiation was temperature independent, while the formation of voids was the main cause of irradiation induced hardening.
INTERNATIONAL JOURNAL OF REFRACTORY METALS & HARD MATERIALS
(2023)
Article
Food Science & Technology
I. Jebalia, G. Della Valle, S. Guessasma, M. Kristiawan
Summary: In this study, models of dense starch-protein composites were obtained by extrusion of pea flour and blends of pea starch and pea protein isolate. The morphology of the composites was examined using microscopy, and their mechanical properties were tested. The results showed that protein aggregates were dispersed in the starch matrix, and increasing particle volume fractions weakened the mechanical properties of the composites. The mechanical behavior of the composites did not follow simple mixing laws, and finite element modeling was able to describe the hardening behavior of the composites.
FOOD RESEARCH INTERNATIONAL
(2022)
Article
Materials Science, Multidisciplinary
Nikolaos Aravas, Ioanna Papadioti
Summary: A non-local gradient plasticity model for porous metals accounting for deformation-induced anisotropy is introduced, incorporating the evolution of porosity and anisotropy due to changes in void shape and orientation. The model's mathematical characteristics are analyzed, showing a higher hardening modulus compared to the local model, leading to elliptic behavior and eliminating discontinuous solutions. Numerical integration algorithms, boundary value problem implementation, and analytical methods for eigenvector calculations are discussed, with the non-local model implemented in ABAQUS for various example problems.
JOURNAL OF THE MECHANICS AND PHYSICS OF SOLIDS
(2021)
Article
Engineering, Mechanical
S. Falco, N. Fogell, S. Kasinos, L. Iannucci
Summary: This paper presents an approach to evaluate the macroscopic properties of ceramic materials based on micromechanical simulations performed on Representative Volume Elements (RVEs). The results show good agreement between numerical simulations, experimental measurements, and analytical calculations, providing an effective prediction of elastic deformation and brittle failure behavior.
INTERNATIONAL JOURNAL OF MECHANICAL SCIENCES
(2022)
Article
Nanoscience & Nanotechnology
Yang Liu, Weifeng Wan, Fionn P. E. Dunne
Summary: This study investigates the intrinsic crystal slip system properties and their influence on stress, stress relaxation, and strain rate sensitivity (SRS) using experimental testing, digital image correlation strain measurement, electron backscatter detection, and crystal plasticity modelling. The findings show that Zircaloy-4 exhibits significant SRS behavior, which is accurately captured by the polycrystal plasticity model. The model also predicts the effects of texture and slip system activation on lattice strain rate sensitivities.
MATERIALS SCIENCE AND ENGINEERING A-STRUCTURAL MATERIALS PROPERTIES MICROSTRUCTURE AND PROCESSING
(2022)
Article
Engineering, Mechanical
Tongming Qu, Shaoheng Guan, Y. T. Feng, Gang Ma, Wei Zhou, Jidong Zhao
Summary: This study aims to develop a deep active learning strategy to improve the data-driven constitutive modelling of granular materials. The results confirm the importance of active learning in this field and suggest its potential application in other data-centric applications in various science and engineering fields.
INTERNATIONAL JOURNAL OF PLASTICITY
(2023)
Article
Materials Science, Multidisciplinary
Mikhail Khadyko, Bjorn Hakon Frodal, Odd Sture Hopperstad
Summary: The study proposed a regularized model of porous crystal plasticity, which can describe the plastic behavior of materials under various stresses and be applied in a finite element code. Simulation results demonstrate the model's capability to effectively explain the interaction between different modes of strain localization, as well as the initiation and propagation of ductile fracture.
INTERNATIONAL JOURNAL OF FRACTURE
(2021)
Article
Chemistry, Physical
Amanda Guedes Nogueira Matuda, Marcos Paulo Motta Silveira, Guilherme Schmitt de Andrade, Amanda Maria de Oliveira Dal Piva, Joao Paulo Mendes Tribst, Alexandre Luiz Souto Borges, Luca Testarelli, Gabriella Mosca, Pietro Ausiello
Summary: The study found that using bulk-fill flowable composite resin significantly reduces the magnitude of polymerization shrinkage stress. The larger the cavity and the volume of material needed to restore the tooth, the greater the residual stress on enamel and dentin tissue.
Article
Materials Science, Multidisciplinary
K. Frydrych, F. J. Dominguez-Gutierrez, M. J. Alava, S. Papanikolaou
Summary: Recently developed CSAs are chemically disordered materials with high concentrations of multiple elemental species randomly arranged on a crystalline lattice. They possess excellent physical properties, making them attractive for industries operating in extreme environments. This paper presents a continuum plasticity model for equiatomic five-element CSAs, which captures the inherent disorder associated with lattice distortions through a single parameter alpha. Molecular dynamics simulations of different CSAs are performed to validate the proposed model, which is then applied to nanoindentation tests for various crystallographic orientations using the finite element method.
MECHANICS OF MATERIALS
(2023)
Article
Engineering, Mechanical
A. J. Awang Draup, B. Rodgers, P. B. Prangnell, Q. M. Li, M. J. Lunt, J. D. Robson
Summary: This paper develops a novel multiscale model that accurately predicts the performance of welds under blast loading by capturing the effect of welding on the microstructure and linking it to the material behavior.
INTERNATIONAL JOURNAL OF IMPACT ENGINEERING
(2022)
Article
Materials Science, Multidisciplinary
Spilios Dellis, Xiazi Xiao, Dmitry Terentyev, Konstantina Mergia, Spyros Krimpalis, Alexander Bakaev, Spyros Messoloras
Summary: The study investigated the effect of high-temperature neutron irradiation on the mechanical properties of single-crystal tungsten W(100) and found that while the irradiated tungsten exhibited increased hardness, its values of Young's modulus, shear modulus, and Poisson ratio remained unaffected. The study also utilized finite element method modeling to deduce the contributions of neutron irradiation defects to plastic deformation during the indentation process.
JOURNAL OF NUCLEAR MATERIALS
(2021)
Article
Engineering, Multidisciplinary
A. Cacoilo, R. Moura, F. Teixeira-Dias, A. Azevedo, F. Coghe, R. A. F. Valente
Summary: Developing innovative armour systems to protect against various attacks is crucial for personal, social, and national security. Specifically, high protection level helmets are essential for battlefield use. Developing evaluation methods to predict injuries and trauma is of major importance for helmet design.
DEFENCE TECHNOLOGY
(2021)
Article
Engineering, Biomedical
Pablo J. Blanco, Carlos A. Bulant, Cristiano G. Bezerra, Gonzalo D. Maso Talou, Fabio A. Pinton, Paulo G. P. Ziemer, Raul A. Feijoo, Hector M. Garcia-Garcia, Pedro A. Lemos
Summary: This study compares the geometric features of coronary vessels obtained from different modalities, analyzes the agreement and discrepancies of geometric indexes, and discusses the reliability and significance of coronary vascular geometry in the interpretation of geometric risk factors and characterization of coronary artery disease.
INTERNATIONAL JOURNAL FOR NUMERICAL METHODS IN BIOMEDICAL ENGINEERING
(2021)
Article
Biophysics
Pablo J. Blanco, Carlos A. Bulant, Gonzalo D. Ares, Pedro A. Lemos, Raul A. Feijoo
Summary: The study introduces a modeling framework to investigate the effects of collateral circulation on coronary blood flow physiology, utilizing a prototype model of the coronary tree integrated with the concept of Collateral Flow Index (CFI). The research discusses the role of model parameters associated with collateral circuitry and explores the impact of collateral circulation on FFR values, providing physically-realizable solutions.
BIOMECHANICS AND MODELING IN MECHANOBIOLOGY
(2021)
Article
Cardiac & Cardiovascular Systems
Pablo J. Blanco, Carlos A. Bulant, Cristiano Guedes Bezerra, Pedro A. Lemos, Hector M. Garcia-Garcia
Summary: Computed tomography angiography (CTA) and intravascular ultrasound (IVUS)-derived minimum lumen areas have moderate diagnostic efficiency in identifying hemodynamically severe coronary stenoses, with IVUS slightly outperforming CTA. CTA-derived MLA showed poorer correlation with FFR lesions compared to that derived from IVUS.
CORONARY ARTERY DISEASE
(2022)
Editorial Material
Cardiac & Cardiovascular Systems
J. David Spence, Lucas O. Muller, Pablo J. Blanco
EUROPEAN HEART JOURNAL
(2022)
Article
Engineering, Biomedical
Pablo J. Blanco, Gabriela H. Vargas dos Santos, Carlos A. Bulant, Alonso M. Alvarez, Fredric A. P. Oliveira, Gabriella Cunha-Lima, Pedro A. Lemos
Summary: The study analyzes geometric data of the left main coronary bifurcation in angiographically normal patients and hemodynamic data generated from blood flow models, investigating the relationship between allometric laws and flow distribution. Through simulation-based study, boundary conditions are defined and an iterative strategy is proposed, leading to the conclusion that a power law exponent of 7/3 results in a good balance of wall shear stress between daughter vessels.
MEDICAL ENGINEERING & PHYSICS
(2022)
Article
Biophysics
L. A. Mansilla Alvarez, C. A. Bulant, G. D. Ares, R. A. Feijoo, P. J. Blanco
Summary: This study evaluated the feasibility of using a mid-fidelity numerical strategy in the diagnosis of coronary stenosis, optimized through randomly selected vascular geometric feature samples. The results showed that the strategy can effectively estimate the relevant indicators with lower errors and computational costs.
BIOMECHANICS AND MODELING IN MECHANOBIOLOGY
(2022)
Article
Computer Science, Artificial Intelligence
Pablo J. Blanco, Paulo G. P. Ziemer, Carlos A. Bulant, Yasushi Ueki, Ronald Bass, Lorenz Raber, Pedro A. Lemos, Hector M. Garcia-Garcia
Summary: The study proposes a machine learning approach for automatically extracting lumen and vessel boundaries from IVUS datasets, delivering accurate segmentations and potentially useful clinical applications.
MEDICAL IMAGE ANALYSIS
(2022)
Article
Microbiology
Lucas Vellasco, Erik Svensjo, Carlos Alberto Bulant, Pablo Javier Blanco, Fabio Nogueira, Gilberto Domont, Natalia Pinto de Almeida, Clarissa Rodrigues Nascimento, Danielle Silva-dos-Santos, Carla Eponina Carvalho-Pinto, Emiliano Horacio Medei, Igor C. Almeida, Julio Scharfstein
Summary: Microangiopathy may worsen the clinical outcome of Chagas disease. This study used intravital microscopy to investigate microcirculatory alterations in the hamster cheek pouch infected by GFP-expressing T. cruzi. The findings suggest that intracellular amastigotes stimulate angiogenesis and enhance the delivery of plasma-borne nutrients and factors, benefiting the host-parasite relationship.
Article
Engineering, Multidisciplinary
L. A. Mansilla Alvarez, C. A. Bulant, G. D. Ares, R. A. Feijoo, P. J. Blanco
Summary: In this study, a novel fluid-structure interaction algorithm is proposed for simulating blood flow in three-dimensional deformable vessels. The method extends a mid-fidelity simulation approach by considering the distensibility of the vessel wall, and its effectiveness is verified through extensive numerical validations.
COMPUTER METHODS IN APPLIED MECHANICS AND ENGINEERING
(2022)
Article
Multidisciplinary Sciences
Leyla Noroozbabaee, Pablo J. Blanco, Soroush Safaei, David P. Nickerson
Summary: We review a collection of published renal epithelial transport models and build a consistent and reusable mathematical model that can reproduce many observations and predictions from the literature. The flexible modular model can be adapted to specific configurations of epithelial transport, and this work focuses on transport in the proximal convoluted tubule of the renal nephron.
Article
Cardiac & Cardiovascular Systems
Guy F. A. F. Prado, Pablo J. Blanco, Carlos A. Bulant, Gonzalo D. Ares, Jose Mariani, Adriano Caixeta, Breno O. Almeida, Stefano Garzon, Fabio A. Pinton, Emanuele Barbato, Flavio L. Ribichini, Gabor G. Toth, Felix Mahfoud, William Wijns, Hector M. Garcia-Garcia, Pedro A. Lemos
Summary: This study investigated the relationship between the spatial geometry of coronary arteries and the severity and composition of coronary artery disease (CAD) using computational methods. The results showed that three-dimensional geometric indexes were associated with the degree and composition of atherosclerosis in coronary arteries, and this association remained significant even after adjusting for clinical characteristics.
CATHETERIZATION AND CARDIOVASCULAR INTERVENTIONS
(2023)
Article
Mathematics, Applied
Raul A. Feijoo, Pablo J. Blanco, Eduardo A. de Souza A. Neto, Pablo J. Sanchez
Summary: This contribution provides a comprehensive analysis of the mechanical equilibrium problem for a solid with microstructure. The authors propose a new minimal kinematical restriction (MKR)-based model to approximate the reference solution at low computational cost. The findings have important implications for multiscale theories and the understanding of mechanical equilibrium problems with microstructure.
COMPUTATIONAL & APPLIED MATHEMATICS
(2023)
Review
Medicine, Research & Experimental
Robyn W. May, Gonzalo Maso D. Talou, Alys R. Clark, Jonathan P. Mynard, Joseph J. Smolich, Pablo J. Blanco, Lucas O. Mueller, Thomas L. Gentles, Frank H. Bloomfield, Soroush Safaei
Summary: Computational modeling is widely used in the study of cardiovascular hemodynamics for medical research and improving the diagnosis and treatment of cardiovascular diseases. Most existing cardiovascular models focus on the adult circulatory system, but the perinatal period is unique as cardiovascular physiology undergoes significant changes. This review discusses computational models of the cardiovascular system in early life, their applications, and proposes a roadmap for developing an open-source model spanning fetal, perinatal, and postnatal periods.
WIRES MECHANISMS OF DISEASE
(2023)
Article
Engineering, Biomedical
Morena Celant, Eleuterio F. Toro, Giulia Bertaglia, Susanna Cozzio, Valerio Caleffi, Alessandro Valiani, Pablo J. Blanco, Lucas O. Muller
Summary: Arterial hypertension, a major risk factor for cardiovascular diseases, leads to millions of deaths worldwide annually. Computational models can quantify the role of different components in hypertension. In this study, a global closed-loop multi-scale mathematical model of the human circulation is used to simulate a hypertensive scenario, reproducing alterations in the cardiovascular system. The model outputs are validated against current knowledge of the impact of hypertension on the cardiovascular system.
INTERNATIONAL JOURNAL FOR NUMERICAL METHODS IN BIOMEDICAL ENGINEERING
(2023)
Article
Mechanics
P. J. Blanco, P. J. Sanchez, F. F. Rocha, S. Toro, R. A. Feijoo
Summary: This study focuses on developing a multiscale framework for solid media with a random distribution of voids. A novel multiscale mechanical formulation is proposed to model the material behavior, and a new homogenization approach is introduced. Numerical experiments are conducted to support the concepts presented in this study.
INTERNATIONAL JOURNAL OF SOLIDS AND STRUCTURES
(2023)