Review
Gastroenterology & Hepatology
Irving Levine, Arvind J. Trindade
Summary: Endoscopic ultrasound tissue acquisition, through EUS-FNA and EUS-FNB, is commonly used for pancreatic mass lesions, subepithelial lesions, and lymph node biopsy. While both methods are safe and offer high diagnostic value, there are potential limitations with EUS-FNA related to cytological aspirations. Comparative trials between EUS-FNA and EUS-FNB for pancreatic mass lesions have shown conflicting results, with the need for further large-scale studies for other types of lesions.
WORLD JOURNAL OF GASTROENTEROLOGY
(2021)
Article
Surgery
Ammar Javed, Alessandra Pulvirenti, Samrah Razi, Jian Zheng, Theodoros Michelakos, Yurie Sekigami, Elizabeth S. Thompson, David Klimstra, Vikram D. Deshpande, Aatur J. Singhi, Matthew L. Weiss, Christopher L. Wolfgang, John C. Cameron, Alice C. H. Wei, Amer R. Zureikat, Cristina Ferrone, Jin He
Summary: A multicenter retrospective study found that the concordance between cytological grade (c-grade) and histopathological grade (h-grade) in PanNETs patients was 80.4%, and it was associated with tumor size, with the highest concordance observed in PanNETs smaller than 2cm.
Article
Oncology
Shubo Pan, Jie Liu, Jiefang Guo, Qilin Zhu, Liangjing Wang, Xiaohua Shi
Summary: Based on a 2-center retrospective study, EUS-FNA was clinically significant in about 40% of low-risk PCLs, especially in young, large cyst size, and overweight patients.
FRONTIERS IN ONCOLOGY
(2022)
Article
Endocrinology & Metabolism
Alessandro Gambella, Enrico Costantino Falco, Jasna Metovic, Francesca Maletta, Claudio De Angelis, Roberta Maragliano, Silvia Uccella, Donatella Pacchioni, Mauro Papotti
Summary: Pancreatic neuroendocrine tumors (PanNETs) with amyloid-rich stromal component present unique diagnostic challenges in EUS-guided fine needle aspiration cytology (EUS-FNAC). The neuroendocrine nature is confirmed by immunocytochemistry, while the amyloid stroma is identified by positive Congo red staining.
ENDOCRINE PATHOLOGY
(2021)
Article
Medicine, General & Internal
Eleni Koukoulioti, Georgios Tziatzios, Mario Tadic, Stavros Dimitriadis, Paraskevas Gkolfakis, Ekaterini Politi, Tajana Stoos-Veic, Petra Turcic, Alexandros Chatzidakis, Lazaros-Dimitrios Lazaridis, Maria Farmaki, Antonios Vezakis, Konstantinos Triantafyllou, Andreas Polydorou, Ioannis S. Papanikolaou
Summary: This study found that 2 passes of EUS-FNA had similar diagnostic yield compared to 3 passes for solid pancreatic masses, suggesting that there might be no significant incremental tissue yield when 3 passes are performed.
Article
Gastroenterology & Hepatology
Kazunaga Ishigaki, Yousuke Nakai, Naoki Sasahira, Kazuya Sugimori, Katsuya Kitamura, Tomohisa Iwai, Saburo Matsubara, Kenji Shimura, Takao Itoi, Shomei Ryozawa, Jun Ushio, Shinpei Doi, Hiroo Imazu, Iruru Maetani, Hiroyuki Isayama
Summary: This multicenter prospective study confirmed the high diagnostic accuracy of EUS-FNB using the 22-gauge Franseen needle for pancreatic solid lesions, with high per pass and overall diagnostic accuracy. Factors affecting diagnostic accuracy include tumor size, puncture method, and use of suction.
JOURNAL OF GASTROENTEROLOGY AND HEPATOLOGY
(2021)
Article
Medicine, General & Internal
Miruna Patricia Olar, Sorana D. Bolboaca, Cristina Pojoga, Ofelia Mosteanu, Marcel Gheorghiu, Radu Seicean, Ioana Rusu, Zeno Sparchez, Nadim Al Hajjar, Andrada Seicean
Summary: Endoscopic ultrasound fine needle aspiration (EUS-FNA) cytology is useful in the differentiation of pancreatic cysts, with higher sensitivity when the solid component is targeted. This study aimed to evaluate the diagnostic value of contrast-enhanced guided EUS-FNA (CH-EUS-FNA) in enhanced mural nodules and discrimination between different cysts. Results showed that mucinous cysts had higher arterial enhancement on contrast-enhanced endoscopic ultrasound (CH-EUS), and CH-EUS-FNA identified mucinous cysts and malignancy with high sensitivity and specificity. A comprehensive assessment of solid components using contrast-enhanced endoscopic ultrasound is important for the identification of malignant cysts.
Article
Environmental Sciences
Marcel Gheorghiu, Zeno Sparchez, Ioana Rusu, Sorana D. Bolboaca, Radu Seicean, Cristina Pojoga, Andrada Seicean
Summary: The study aimed to evaluate the diagnostic value of Elastography endoscopic ultrasound fine-needle aspiration (E-EUS-FNA) compared to B-mode EUS-FNA in solid pancreatic masses. The results showed that E-EUS-FNA was not superior to B-mode EUS-FNA.
INTERNATIONAL JOURNAL OF ENVIRONMENTAL RESEARCH AND PUBLIC HEALTH
(2022)
Article
Medicine, General & Internal
Hyun Seok Lee, Eaum-Seok Lee
Summary: This article reports a case of an unexpected catecholamine crisis that occurred after EUS-FNB. Despite being considered relatively safe, careful evaluation is required when performing biopsy of lesions around the aorta.
Review
Medicine, General & Internal
Galab M. Hassan, Louise Laporte, Sarto C. Paquin, Charles Menard, Anand Sahai, Benoit Masse, Helen Trottier
Summary: A systematic review and meta-analysis compared the diagnostic accuracy of EUS-guided FNA and FNB for pancreatic cancer. The meta-analysis showed that EUS-FNB had superior diagnostic accuracy compared to EUS-FNA for pancreatic cancer.
Review
Gastroenterology & Hepatology
Zhiwang Li, Wei Liu, Xiaoda Xu, Peiyu Li
Summary: This study compared the diagnostic value and safety of endoscopic ultrasound-guided fine-needle aspiration (EUS-FNA) and endoscopic ultrasound-guided fine-needle biopsy (EUS-FNB) in sampling solid lesions, showing that FNB has better diagnostic accuracy and tissue core rates in solid gastrointestinal lesions, with fewer needle passes, but no difference in solid pancreatic disease.
JOURNAL OF CLINICAL GASTROENTEROLOGY
(2022)
Review
Gastroenterology & Hepatology
Masayuki Kitano, Kosuke Minaga, Keiichi Hatamaru, Reiko Ashida
Summary: EUS-FNA is a first-line procedure for diagnosing pancreatic cancer with high accuracy and low complication rate, but its ability to diagnose small lesions is limited. The dilemma of using preoperative EUS-FNA for diagnosing resectable pancreatic body and tail cancer challenges gastroenterologists and requires careful consideration of the benefits and risks in each case.
DIGESTIVE ENDOSCOPY
(2022)
Article
Oncology
Elie M. Ghabi, Joseph R. Habib, Sami Shoucair, Ammar A. Javed, Jonathan Sham, William R. Burns, John L. Cameron, Syed Z. Ali, Eun Ji Shin, Paolo Giorgio Arcidiacono, Claudio Doglioni, Massimo Falconi, Jun Yu, Stefano Partelli, Jin He
Summary: The study investigated the feasibility of detecting somatic mutations in endoscopic ultrasound-guided, fine-needle aspiration (EUS-FNA) specimens of well-differentiated pancreatic neuroendocrine tumors (PanNETs). The results showed that next-generation sequencing (NGS) can detect somatic mutations in EUS-FNA specimens and there was mutational concordance between EUS-FNA specimens and primary tumors.
ANNALS OF SURGICAL ONCOLOGY
(2023)
Article
Medicine, General & Internal
Taro Hanaoka, Kosuke Okuwaki, Hiroshi Imaizumi, Yusuke Imawari, Tomohisa Iwai, Hiroshi Yamauchi, Rikiya Hasegawa, Kai Adachi, Masayoshi Tadehara, Takahiro Kurosu, Masafumi Watanabe, Akihiro Tamaki, Mitsuhiro Kida, Wasaburo Koizumi
Summary: This article reports the first English publication of a case of pancreatic schwannoma, in which surgery was avoided based solely on the pathological diagnosis made through endoscopic ultrasound-guided fine-needle aspiration findings.
Article
Surgery
Fausto Rosa, Mihai Rimbas, Gianenrico Rizzatti, Giuseppe Quero, Claudio Fiorillo, Michele Impagnatiello, Francesca D'Aversa, Guido Costamagna, Sergio Alfieri, Alberto Larghi
Summary: The study evaluated the safety and efficacy of preoperative endoscopic ultrasound guided fine needle tattooing (EUS-FNT) for detecting pancreatic neuroendocrine tumors (pNETs). Results showed that EUS-guided FNT is a safe and useful method to mark preoperatively small pNETs, with all identified tumors successfully tattooed in one session and no interference with specimen evaluation during pathological examination.
SURGICAL ENDOSCOPY AND OTHER INTERVENTIONAL TECHNIQUES
(2021)
Article
Gastroenterology & Hepatology
Swathi Eluri, William R. Brugge, Ebubekir S. Daglilar, Sara A. Jackson, Mindi A. Styn, Keith M. Callenberg, Derek C. Welch, Todd M. Barr, Lucas C. Duits, Jacques J. Bergman, Nicholas J. Shaheen
AMERICAN JOURNAL OF GASTROENTEROLOGY
(2015)
Article
Gastroenterology & Hepatology
Won Jae Yoon, Ebubekir S. Daglilar, Michal Kamionek, Mari Mino-Kenudson, William R. Brugge
DIGESTIVE ENDOSCOPY
(2016)
Article
Gastroenterology & Hepatology
Cetin Karaca, Ebubekir S. Daglilar, Ozlem Mutluay Soyer, Mine Gulluoglu, William R. Brugge
GASTROINTESTINAL ENDOSCOPY
(2017)
Article
Surgery
Mustafa Atar, Abdurrahman Kadayifci, Ebubekir Daglilar, Catherine Hagen, Carlos Fernandez-del Castillo, William R. Brugge
SURGICAL ENDOSCOPY AND OTHER INTERVENTIONAL TECHNIQUES
(2018)
Article
Pharmacology & Pharmacy
Francis E. Dailey, Erica P. Turse, Ebubekir Daglilar, Veysel Tahan
CURRENT OPINION IN PHARMACOLOGY
(2019)
Review
Medicine, General & Internal
Harleen Kaur Chela, Syed Bilal Pasha, Omer Basar, Ebubekir Daglilar, Veysel Tahan
WORLD JOURNAL OF CLINICAL CASES
(2020)
Article
Medicine, Research & Experimental
Mustafa Gandhi, Zahid Ijaz Tarar, Umer Farooq, Saad Saleem, Harleen Kaur Chela, Ebubekir Daglilar
Summary: During the COVID-19 pandemic, the timing of esophagogastroduodenoscopy (EGD) in variceal bleeding patients was significantly delayed for those who tested positive for COVID-19. The delay in EGD resulted in increased mortality and ICU admissions. However, COVID-19 infection did not affect the odds of sepsis or vasopressor use, and the hospital outcomes were similar between COVID-positive and -negative patients.
Article
Medicine, Research & Experimental
Mustafa Gandhi, Harleen Kaur Chela, Hamza Ertugrul, Alhareth Al Juboori, Karthik Gangu, Deepthi Rao, Ebubekir Daglilar
Summary: Gastric cancer is a global malignancy with varied presentations. The detection of metastatic gastric tumors plays a crucial role in treatment and prognosis compared to primary gastric tumors. This study presents a series of cases of metastatic gastric tumors, depicting their clinical, endoscopic, and histological characteristics.
Review
Medicine, Research & Experimental
Harleen Kaur Chela, Karthik Gangu, Hamza Ertugrul, Alhareth Al Juboori, Ebubekir Daglilar, Veysel Tahan
Summary: Esophageal cancer is a devastating malignancy with diverse underlying factors, including inflammation. Diagnosis is based on clinical symptomatology, imaging, and endoscopy, and treatment and prognosis depend on the disease stage.
Article
Medicine, Research & Experimental
Karthik Gangu, Aniesh Bobba, Harleen Kaur Chela, Omer Basar, Robert W. Min, Veysel Tahan, Ebubekir Daglilar
Summary: Untreated biliary tract diseases during hospitalization can lead to worse outcomes. Our study reveals that postponing definitive management to a subsequent visit is associated with higher 30-day readmission rates, increased mortality rates, and added financial burden for patients.
Review
Medicine, General & Internal
Zahid Ijaz Tarar, Muhammad Usman Zafar, Umer Farooq, Omer Basar, Veysel Tahan, Ebubekir Daglilar
Summary: Celiac disease is an autoimmune disorder that affects genetically predisposed individuals who are sensitive to gluten, mainly impacting the intestines. Diagnosis requires clinical symptoms, serological testing, and small intestinal biopsies. Patients need close follow-up for treatment progress, and collaboration with a dietitian is recommended.
JOURNAL OF INVESTIGATIVE MEDICINE HIGH IMPACT CASE REPORTS
(2021)
Article
Medicine, General & Internal
Omer Basar, Francis Dailey, Erica Dailey, Veysel Tahan, Ebubekir Daglilar
Summary: Gastrointestinal side effects of interferon therapy for chronic hepatitis C virus infection are non-specific, but rarely can cause inflammatory bowel disease such as Crohn's disease. Monitoring symptoms and test results in patients undergoing interferon therapy and avoiding its use may help prevent complications related to inflammatory bowel disease.
CUREUS JOURNAL OF MEDICAL SCIENCE
(2021)
Review
Medicine, General & Internal
Zahid Ijaz Tarar, Veysel Tahan, Feng Yin, Ebubekir Daglilar
Summary: This is a case report of a 69-year-old female patient with scleroderma who presented with hyperplastic polyp of the esophagus, leading to symptoms of worsening dysphagia, regurgitation of food, and non-cardiac chest pain. Treatment included anti-acid therapy and outpatient upper endoscopy, which resulted in no residual polyp.
CUREUS JOURNAL OF MEDICAL SCIENCE
(2021)
Article
Medicine, General & Internal
Ebubekir Daglilar, Sean E. Connolly, Veysel Tahan, Ari Cohen, George Therapondos
CUREUS JOURNAL OF MEDICAL SCIENCE
(2020)
Article
Medicine, General & Internal
Muhammad F. Mubarak, Ebubekir S. Daglilar, Thom Smilari, Arnab Ray