The convergence of DNA damage checkpoint pathways and androgen receptor signaling in prostate cancer

Targeted Prostate Cancer Screening in BRCA1 and BRCA2 Mutation Carriers: Results from the Initial Screening Round of the IMPACT Study

(2014) Elizabeth K. Bancroft et al.   EUROPEAN UROLOGY

Modernizing the Nonhomologous End-Joining Repertoire: Alternative and Classical NHEJ Share the Stage

(2013) Ludovic Deriano et al.   Annual Review of Genetics

Castration Therapy Results in Decreased Ku70 Levels in Prostate Cancer

(2013) F. L. T. Al-Ubaidi et al.   CLINICAL CANCER RESEARCH

The role of BRCA1 and BRCA2 in prostate cancer

(2013) Roy Jensen   Frontiers in Bioscience-Landmark

DNA Damage Response: Three Levels of DNA Repair Regulation

(2013) B. M. Sirbu et al.   Cold Spring Harbor Perspectives in Biology

Androgen Receptor Signaling Regulates DNA Repair in Prostate Cancers

(2013) W. R. Polkinghorn et al.   Cancer Discovery

GADD45 Proteins: Central Players in Tumorigenesis

(2012) R. E. Tamura et al.   CURRENT MOLECULAR MEDICINE

Minireview: The Androgen Receptor in Breast Tissues: Growth Inhibitor, Tumor Suppressor, Oncogene?

(2012) T. E. Hickey et al.   MOLECULAR ENDOCRINOLOGY

Inactivation of ATM/ATR DNA Damage Checkpoint Promotes Androgen Induced Chromosomal Instability in Prostate Epithelial Cells

(2012) Yung-Tuen Chiu et al.   PLoS One

Testosterone promotes DNA damage response under oxidative stress in prostate cancer cell lines

(2012) Hisamitsu Ide et al.   PROSTATE

Removal of Shelterin Reveals the Telomere End-Protection Problem

(2012) A. Sfeir et al.   SCIENCE

Dual Roles of PARP-1 Promote Cancer Growth and Progression

(2012) M. J. Schiewer et al.   Cancer Discovery

Mechanistic Rationale for Inhibition of Poly(ADP-Ribose) Polymerase in ETS Gene Fusion-Positive Prostate Cancer

(2011) J. Chad Brenner et al.   CANCER CELL

Hallmarks of Cancer: The Next Generation

(2011) Douglas Hanahan et al.   CELL

Transcription-Induced DNA Double Strand Breaks: Both Oncogenic Force and Potential Therapeutic Target?

(2011) M. C. Haffner et al.   CLINICAL CANCER RESEARCH

Androgen-Induced TMPRSS2:ERG Fusion in Nonmalignant Prostate Epithelial Cells

(2010) N. C. Bastus et al.   CANCER RESEARCH

Mechanisms of ATR-mediated checkpoint signalling

(2010) Veronique et al.   Frontiers in Bioscience-Landmark

Alternative end-joining catalyzes class switch recombination in the absence of both Ku70 and DNA ligase 4

(2010) Cristian Boboila et al.   JOURNAL OF EXPERIMENTAL MEDICINE

External irradiation with or without long-term androgen suppression for prostate cancer with high metastatic risk: 10-year results of an EORTC randomised study

(2010) Michel Bolla et al.   LANCET ONCOLOGY

The DNA Damage Response: Making It Safe to Play with Knives

(2010) Alberto Ciccia et al.   MOLECULAR CELL

Androgen-induced TOP2B-mediated double-strand breaks and prostate cancer gene rearrangements

(2010) Michael C Haffner et al.   NATURE GENETICS

Alternative end-joining is suppressed by the canonical NHEJ component Xrcc4–ligase IV during chromosomal translocation formation

(2010) Deniz Simsek et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

DNA mismatch repair and the transition to hormone independence in breast and prostate cancer

(2009) Lynn Martin et al.   CANCER LETTERS

Nuclear Receptor-Induced Chromosomal Proximity and DNA Breaks Underlie Specific Translocations in Cancer

(2009) Chunru Lin et al.   CELL

Tumor Suppressor BRCA1 Is Expressed in Prostate Cancer and Controls Insulin-like Growth Factor I Receptor (IGF-IR) Gene Transcription in an Androgen Receptor-Dependent Manner

(2009) H. Schayek et al.   CLINICAL CANCER RESEARCH

Kinases that control the cell cycle in response to DNA damage: Chk1, Chk2, and MK2

(2009) H Christian Reinhardt et al.   CURRENT OPINION IN CELL BIOLOGY

Roles for NBS1 in Alternative Nonhomologous End-Joining of V(D)J Recombination Intermediates

(2009) Ludovic Deriano et al.   MOLECULAR CELL

Role of mammalian Mre11 in classical and alternative nonhomologous end joining

(2009) Anyong Xie et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

Role of Mre11 in chromosomal nonhomologous end joining in mammalian cells

(2009) Emilie Rass et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

DNA Damage, Aging, and Cancer

(2009) Jan H.J. Hoeijmakers   NEW ENGLAND JOURNAL OF MEDICINE

Rad9 Has a Functional Role in Human Prostate Carcinogenesis

(2008) A. Zhu et al.   CANCER RESEARCH

Site-specific Androgen Receptor Serine Phosphorylation Linked to Epidermal Growth Factor-dependent Growth of Castration-recurrent Prostate Cancer

(2008) Liliana A. Ponguta et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Epidermal Growth Factor-Dependent Phosphorylation and Ubiquitinylation of MAGE-11 Regulates Its Interaction with the Androgen Receptor

(2008) S. Bai et al.   MOLECULAR AND CELLULAR BIOLOGY

Genome instability: a mechanistic view of its causes and consequences

(2008) Andrés Aguilera et al.   NATURE REVIEWS GENETICS

Low frequency of microsatellite instability in hereditary prostate cancer

(2003) A.-K. Åhman et al.   BJU INTERNATIONAL