PXD101 potentiates hormonal therapy and prevents the onset of castration-resistant phenotype modulating androgen receptor, HSP90, and CRM1 in preclinical models of prostate cancer

The suppression of prostate LNCaP cancer cells growth by Selenium nanoparticles through Akt/Mdm2/AR controlled apoptosis

(2011) Ling Kong et al.   BIOMATERIALS

Histone deacetylase inhibitor valproic acid suppresses the growth and increases the androgen responsiveness of prostate cancer cells

(2011) Yu-Wei Chou et al.   CANCER LETTERS

Dual EGFR/HER2 Inhibition Sensitizes Prostate Cancer Cells to Androgen Withdrawal by Suppressing ErbB3

(2011) L. Chen et al.   CLINICAL CANCER RESEARCH

Androgen Receptor Cofactors in Prostate Cancer: Potential Therapeutic Targets of Castration-Resistant Prostate Cancer

(2011) Masaki Shiota et al.   CURRENT CANCER DRUG TARGETS

Hormonal Therapy Promotes Hormone-Resistant Phenotype by Increasing DNMT Activity and Expression in Prostate Cancer Models

(2011) Giovanni Luca Gravina et al.   ENDOCRINOLOGY

Expression of Androgen Receptor Splice Variants in Prostate Cancer Bone Metastases is Associated with Castration-Resistance and Short Survival

(2011) Emma Hörnberg et al.   PLoS One

Modulation of Androgen Receptor Signaling in Hormonal Therapy-Resistant Prostate Cancer Cell Lines

(2011) Rute B. Marques et al.   PLoS One

New agents and strategies for the hormonal treatment of castration-resistant prostate cancer

(2010) Nima Sharifi   EXPERT OPINION ON INVESTIGATIONAL DRUGS

Characterization of Androgen Receptor Structure and Nucleocytoplasmic Shuttling of the Rice Field Eel

(2010) Fang Zhou et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

The epigenome as a therapeutic target in prostate cancer

(2010) Antoinette S. Perry et al.   Nature Reviews Urology

Histone Deacetylases Are Required for Androgen Receptor Function in Hormone-Sensitive and Castrate-Resistant Prostate Cancer

(2009) D. S. Welsbie et al.   CANCER RESEARCH

Sulforaphane destabilizes the androgen receptor in prostate cancer cells by inactivating histone deacetylase 6

(2009) A. Gibbs et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

SNX2112, a Synthetic Heat Shock Protein 90 Inhibitor, Has Potent Antitumor Activity against HER Kinase Dependent Cancers

(2008) S. Chandarlapaty et al.   CLINICAL CANCER RESEARCH

Differential effects of prostate cancer therapeutics on neuroendocrine transdifferentiation

(2008) D. E. Frigo et al.   MOLECULAR CANCER THERAPEUTICS