Article
Medicine, General & Internal
Reagan M. Mogire, Alireza Morovat, John Muthii Muriuki, Alexander J. Mentzer, Emily L. Webb, Wandia Kimita, Francis M. Ndungu, Alex W. Macharia, Clare L. Cutland, Sodiomon B. Sirima, Amidou Diarra, Alfred B. Tiono, Swaib A. Lule, Shabir A. Madhi, Manjinder S. Sandhu, Andrew M. Prentice, Philip Bejon, John M. Pettifor, Alison M. Elliott, Adebowale Adeyemo, Thomas N. Williams, Sarah H. Atkinson
Summary: The study found that vitamin D deficiency rates among young African children were 0.6% and 7.8%, with factors such as country, age, season, inflammation, and malaria influencing the levels. In addition, variations in the GC gene were associated with vitamin D levels.
Article
Nutrition & Dietetics
Faruk Ahmed, Hossein Khosravi-Boroujeni, Moududur Rahman Khan, Anjan Kumar Roy, Rubhana Raqib
Summary: This study found that hypovitaminosis D is highly prevalent among pregnant rural Bangladeshi women. Parity and gestational age are common risk factors for vitamin D deficiency and insufficiency, while a husband's occupation and anaemia status may predict vitamin D insufficiency. Younger age and sub-optimal vitamin A status are risk factors for vitamin D deficiency in this population.
Article
Endocrinology & Metabolism
Mark J. Bolland, Alison Avenell, Andrew Grey
Summary: The prevalence of biochemical osteomalacia is very low, even in individuals with 25OHD levels below 25 nmol/L, with all cases of osteomalacia having 25OHD levels <= 18 nmol/L before supplementation.
CLINICAL ENDOCRINOLOGY
(2021)
Article
Nutrition & Dietetics
Ting-Yi Wang, Hung-Wei Wang, Ming-Yan Jiang
Summary: This study investigated the prevalence of vitamin D deficiency and its association with mortality risk among non-institutional middle-aged and older adults in the United States. The results showed that nearly 20% of the study population were vitamin D deficient and vitamin D deficiency was associated with increased mortality risk.
FRONTIERS IN NUTRITION
(2023)
Article
Endocrinology & Metabolism
John D. Sluyter, Yoshihiko Raita, Kohei Hasegawa, Ian R. Reid, Robert Scragg, Carlos A. Camargo
Summary: Using machine learning models to predict vitamin D deficiency showed higher accuracy in predicting 25(OH)D <25 nmol/L compared to traditional models, suggesting a potential role for machine learning models in participant selection for vitamin D supplement trials.
JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM
(2022)
Review
Public, Environmental & Occupational Health
Mahbubul H. Siddiqee, Badhan Bhattacharjee, Umme Ruman Siddiqi, Mohammad MeshbahurRahman
Summary: The study reveals a highly prevalent and variable vitamin D deficiency among adults in different South Asian countries, with the highest prevalence found in Pakistan, followed by Bangladesh, India, Nepal, and Sri Lanka. The findings could help generate hypotheses and explore factors affecting inter-country variability, and strengthen evidence for governments to prioritize mitigation strategies in the region.
Review
Nutrition & Dietetics
Manuel Rupprecht, Stefan Wagenpfeil, Jakob Schoepe, Reinhold Vieth, Thomas Vogt, Joerg Reichrath
Summary: A meta-analysis was conducted to investigate the impact of oral vitamin D supplementation on serum 25-hydroxyvitamin D levels in healthy adults in Europe. The findings suggest that vitamin D supplementation can significantly increase serum 25(OH)D levels, with the effect influenced by dosage and baseline serum levels.
Article
Endocrinology & Metabolism
Wei Fun Cheong, Shanshan Ji, Amaury Cazenave-Gassiot, Win Pa Pa Thu, Susan Logan, Jane Cauley, Michael S. Kramer, Eu-Leong Yong
Summary: Vitamin D levels were found to be lowest in Indian and Malay women compared to Chinese women, as well as in younger and employed women in Singapore. Deficient cutaneous production was identified as the main reason for hypovitaminosis D in study women. Ethnicity and opportunities for sunlight exposure should be considered in supplementation efforts in regions with abundant sunshine.
ARCHIVES OF OSTEOPOROSIS
(2021)
Article
Nutrition & Dietetics
Avril Beirne, Kevin McCarroll, James Bernard Walsh, Miriam Casey, Eamon Laird, Helene McNulty, Mary Ward, Leane Hoey, Anne M. Molloy, Martin Healy, Catherine Hughes, Sean Strain, Conal Cunningham
Summary: This study found an independent prospective association between vitamin D deficiency and increased hospitalization among older adults. Lower vitamin D concentrations were associated with higher rates of ED attendance and hospital admission, highlighting the potential importance of vitamin D supplementation beyond bone health in this population. Further investigation through randomized controlled trials is needed to evaluate current recommendations regarding vitamin D supplementation.
Article
Nutrition & Dietetics
Caroline Zani Rodrigues, Thais Carlos Correia, Paulo Augusto Ribeiro Neves, Maira Barreto Malta, Marly Augusto Cardoso, Barbara Hatzlhoffer Lourenco
Summary: This study aimed to identify the predictors of 25-hydroxyvitamin D-3 (25(OH)D-3) concentrations in the third trimester of pregnancy. The results showed that seasonality and vitamin A status were significant predictors of 25(OH)D-3 concentrations. Adequate exposure to sunlight and consumption of vitamin A within safe levels can help maintain a good nutritional status of vitamin D during pregnancy.
EUROPEAN JOURNAL OF CLINICAL NUTRITION
(2022)
Article
Pediatrics
Cuneyt Karagol, Aysu Duyan Camurdan
Summary: This study aims to determine the frequency of vitamin D deficiency and its influencing factors in healthy children. The results showed that 18-24.9% of healthy children have vitamin D deficiency or insufficiency. The frequency of vitamin D deficiency increases with age, and the most severe cases are found in adolescent girls. Other risk factors include winter or spring season and living in regions north of the 40th parallel.
EUROPEAN JOURNAL OF PEDIATRICS
(2023)
Article
Nutrition & Dietetics
Aasiya Bano, Saida Abrar, Elisa Brilli, Germano Tarantino, Ali Akbar Bugti, Marco Fabbrini, Gabriele Conti, Silvia Turroni, Mahroo Bugti, Fauzia Afridi, Shah Mureed, Hakeem Zada, Ikram Din Ujjan, Saadia Ashraf, Aamir Ghafoor, Saeed Khan, Amjad Khan
Summary: This study compared the absorption of an innovative phospholipids-sucrester matrix biodelivery vehicle-based Vit D3 preparation with a reference chewable tablet and soft gel capsule Vit D3 formulations in Vit D-deficient healthy adults. The results showed that the phospholipids-sucrester matrix Vit D3 preparation was efficiently absorbed in the gastrointestinal system, achieving higher and sustained circulatory Vit D levels, and can effectively contribute to the body's protection against Vit D deficiency-associated health conditions.
FRONTIERS IN NUTRITION
(2023)
Article
Multidisciplinary Sciences
Jirayu Visuthranukul, Phenphop Phansuea, Pantat Buranakityanon, Prapawan Lerdrungroj, Eakkawit Yamasmith
Summary: This study aimed to determine the prevalence and risk factors of vitamin D deficiency (VDD) in HIV-infected adults receiving antiretroviral therapy (ART) in a tropical area. The study found that increasing age, efavirenz use, male gender, low BMI, protease inhibitors use, and CD4 count lower than 200 cells/mm(3) were associated with vitamin D deficiency.
Article
Nutrition & Dietetics
Buthaina Yusuf Al-Ajlan, Afnan Freije, Sabika Allehdan, Simone Perna
Summary: This study investigated the prevalence of vitamin D deficiency and its risk factors in children and adolescents aged 10 to 19. The results showed a high prevalence of vitamin D deficiency, especially among boys and overweight/obese individuals. Additionally, there was a significant association between vitamin D deficiency and low serum levels of magnesium and phosphate.
Review
Nutrition & Dietetics
Marcela M. Mendes, Anna P. O. Gomes, Maisa M. Araujo, Alexandre S. G. Coelho, Kenia M. B. Carvalho, Patricia B. Botelho
Summary: This review aimed to estimate the prevalence of vitamin D deficiency in South American populations. A total of 96 studies involving 227,758 participants were included. The overall prevalence of vitamin D deficiency was found to be 34.76%. Age, sex, country, latitude, season, and year of publication were factors associated with the prevalence rates. Therefore, public health strategies should address the prevention, detection, and treatment of vitamin D deficiency.
Article
Endocrinology & Metabolism
Albert Shieh, Kristine M. Ruppert, Gail A. Greendale, Yinjuan Lian, Jane A. Cauley, Sherri-Ann Burnett-Bowie, Carrie Karvonen-Guttierez, Arun S. Karlamangla
Summary: Years since the final menstrual period (FMP) is more strongly associated with postmenopausal bone mineral density (BMD) than chronological age, and earlier menopause is associated with more fractures.
JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM
(2022)
Article
Endocrinology & Metabolism
Fjola Johannesdottir, Melissa S. Putman, Sherri-Ann M. Burnett-Bowie, Joel S. Finkelstein, Elaine W. Yu, Mary L. Bouxsein
Summary: The study found that postmenopausal Black women have similar rates of bone loss compared to White women, with lower weight women experiencing greater declines in bone density and microstructure at the radius. Women who lost weight during the follow-up period had higher rates of bone loss, particularly at the tibia, while higher baseline total body fat mass was protective against bone loss.
JOURNAL OF BONE AND MINERAL RESEARCH
(2022)
Article
Health Care Sciences & Services
Sherri-Ann M. Burnett-Bowie, Jessica A. Zeidman, Alexander E. Soltoff, Kylee T. Carden, Aisha K. James, Katrina A. Armstrong
Summary: Racism has negative impacts on health and society, and it is important for the medical community to intervene. This study found that greater awareness of the effects of racism on health is associated with increased likelihood of intervening when a racist encounter is observed or a racist policy is noted.
JOURNAL OF GENERAL INTERNAL MEDICINE
(2022)
Article
Health Care Sciences & Services
Gabrielle Kis Bromberg, Elizabeth A. Gay, Kelsey Hills-Dunlap, Sherri-Ann M. Burnett-Bowie
JOURNAL OF GENERAL INTERNAL MEDICINE
(2022)
Article
Geriatrics & Gerontology
Karina N. Ruiz-Esteves, Jimmitti Teysir, Daria Schatoff, Elaine W. Yu, Sherri-Ann M. Burnett-Bowie
Summary: Osteoporosis and fragility fractures lead to significant morbidity and mortality, with non-White women experiencing disparities in care compared to White women. Further studies and interventions are needed to address these disparities and reduce morbidity and mortality.
Article
Education, Scientific Disciplines
Robin Klein, Nneka N. Ufere, Sarah Schaeffer, Katherine A. Julian, Sowmya R. Rao, Jennifer Koch, Anna Volerman, Erin D. Snyder, Vanessa Thompson, Ishani Ganguli, Sherri-Ann M. Burnett-Bowie, Kerri Palamara
Summary: This study aimed to examine the association between race/ethnicity and clinical performance assessments among internal medicine residents. The research found that underrepresented in medicine residents received lower competency scores, suggesting potential bias in faculty assessment or structural inequities in assessment.
Article
Endocrinology & Metabolism
Sigridur Bjornsdottir, Steven Ing, Deborah M. Mitchell, Tanja Sikjaer, Line Underbjerg, Zaki J. Hassan-Smith, Jad Sfeir, Neil J. Gittoes, Bart L. L. Clarke
Summary: Chronic hypoparathyroidism is a rare disorder characterized by low serum calcium, increased serum phosphorus, and decreased parathyroid hormone. The epidemiology and complications of this disorder are not well understood, but it is associated with significant morbidity and a substantial financial burden.
JOURNAL OF BONE AND MINERAL RESEARCH
(2022)
Article
Psychology, Clinical
Karen P. Jakubowski, Rachel E. Koffer, Karen A. Matthews, Sherri-Ann M. Burnett-Bowie, Carol A. Derby, Elaine W. Yu, Robin Green, Rebecca C. Thurston
Summary: This study found that older women, particularly those with a history of childhood abuse or intimate partner violence, are more vulnerable to adverse psychosocial outcomes during the COVID-19 pandemic. Childhood abuse was associated with elevated anxiety symptoms, household conflict, and nonhousehold family conflict, while IPV was associated with sleep problems and household conflict. No associations were found for depressive symptoms after adjusting for pre-pandemic depression scores. These findings highlight the importance of considering women's trauma histories and pre-pandemic symptoms when examining the psychosocial impacts of the pandemic.
JOURNAL OF TRAUMATIC STRESS
(2023)
Editorial Material
Health Care Sciences & Services
William J. Tate, Sourik Beltran, Sherri-Ann M. Burnett-Bowie
JOURNAL OF GENERAL INTERNAL MEDICINE
(2023)
Article
Endocrinology & Metabolism
Deborah M. Mitchell, Vibha Singhal, Supritha Nimmala, Meghan Lauze, Mary L. Bouxsein, Madhusmita Misra, Miriam A. Bredella
Summary: Using an engineering model to estimate risk, this study found that the risk of fracture decreases 1 year after vertical sleeve gastrectomy but rebounds at year 2.
OSTEOPOROSIS INTERNATIONAL
(2023)
Article
Medicine, General & Internal
Daniel H. Solomon, Leah Santacroce, Aladdin Shadyab, Bernhard Haring, Sherri-Ann M. Burnett-Bowie, Carrie Karvonen-Gutierrez, Alicia Colvin, Rebecca Jackson, Meryl S. LeBoff, Kristine Ruppert, Celina Valencia, Nancy E. Avis, JoAnn E. Manson
Summary: This study derived and validated a risk score for predicting declines in physical health among women in mid-life. The risk score was able to accurately identify women at high risk for significant declines over a 10-year period.
Article
Medicine, Research & Experimental
Han Xie, Isinsu Bastepe, Wen Zhou, Birol Ay, Zara Ceraj, Ignacio A. Portales-Castillo, Eva S. Liu, Sherri-Ann M. Burnett-Bowie, Harald Juppner, Eugene P. Rhee, Murat Bastepe, Petra Simic
Summary: This study found that vitamin D affects the cleavage of iFGF23 by regulating furin enzyme. Mice lacking the vitamin D receptor showed increased cleavage of iFGF23, while inhibition of furin activity prevented the increase in cleavage. This suggests that vitamin D can increase the levels of phosphaturic factor iFGF23 by regulating furin expression.
Article
Endocrinology & Metabolism
Rylee K. Saunders, Kathleen M. Kilroe, Taisha V. Joseph, Signe Caksa, Mary L. Bouxsein, Madhusmita Misra, Deborah M. Mitchell
Summary: The study found that adolescents with T1D may be more vulnerable to calcium deficiency in their diet, and increasing calcium intake could be an effective strategy to optimize bone health in this population.
Article
Endocrinology & Metabolism
Lauren Y. Maldonado, Linette Bosques, Sara J. Cromer, Sharl S. Azar, Elaine W. Yu, Sherri-Ann M. Burnett-Bowie
Summary: Racial and ethnic disparities in screening and treatment of osteoporosis, MtBD, and SCD are significant, and more research is needed.
ENDOCRINOLOGY AND METABOLISM CLINICS OF NORTH AMERICA
(2023)
Letter
Medicine, General & Internal
Jeffrey M. Bloom
NEW ENGLAND JOURNAL OF MEDICINE
(2022)