TROP2 is epigenetically inactivated and modulates IGF-1R signalling in lung adenocarcinoma

Insulin-like growth factor-1 receptor inhibition overcomes gefitinib resistance in mucinous lung adenocarcinoma

(2011) Amandine Hurbin et al.   JOURNAL OF PATHOLOGY

Loss of Trop2 Promotes Carcinogenesis and Features of Epithelial to Mesenchymal Transition in Squamous Cell Carcinoma

(2011) J. Wang et al.   MOLECULAR CANCER RESEARCH

Slug Confers Resistance to the Epidermal Growth Factor Receptor Tyrosine Kinase Inhibitor

(2010) Tzu-Hua Chang et al.   AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE

Defining the pathway to insulin-like growth factor system targeting in cancer

(2010) Steven A. Rosenzweig et al.   BIOCHEMICAL PHARMACOLOGY

Trop2 expression contributes to tumor pathogenesis by activating the ERK MAPK pathway

(2010) Rafael Cubas et al.   Molecular Cancer

Expression of the GA733 gene family and its relationship to prognosis in pulmonary adenocarcinoma

(2010) Hiromi Kobayashi et al.   VIRCHOWS ARCHIV

High coexpression of both insulin-like growth factor receptor-1 (IGFR-1) and epidermal growth factor receptor (EGFR) is associated with shorter disease-free survival in resected non-small-cell lung cancer patients

(2009) V. Ludovini et al.   ANNALS OF ONCOLOGY

Allelic loss on chromosomes 1p32, 9p21, 13q14, 16q22, 17p, and 22q12 in meningiomas associated with meningioangiomatosis and pure meningioangiomatosis

(2009) Na Rae Kim et al.   JOURNAL OF NEURO-ONCOLOGY

p53 controls cancer cell invasion by inducing the MDM2-mediated degradation of Slug

(2009) Shu-Ping Wang et al.   NATURE CELL BIOLOGY

High expression of TROP2 correlates with poor prognosis in pancreatic cancer

(2008) D Fong et al.   BRITISH JOURNAL OF CANCER

A Bicistronic CYCLIN D1-TROP2 mRNA Chimera Demonstrates a Novel Oncogenic Mechanism in Human Cancer

(2008) E. Guerra et al.   CANCER RESEARCH

Deletion of 1p32-p36 Is the Most Frequent Genetic Change and Poor Prognostic Marker in Adenoid Cystic Carcinoma of the Salivary Glands

(2008) P. H. Rao et al.   CLINICAL CANCER RESEARCH

TROP2 expression as prognostic marker for gastric carcinoma

(2008) G Muhlmann et al.   JOURNAL OF CLINICAL PATHOLOGY

Identification of Trop-2 as an oncogene and an attractive therapeutic target in colon cancers

(2008) J. Wang et al.   MOLECULAR CANCER THERAPEUTICS