Rab25 increases cellular ATP and glycogen stores protecting cancer cells from bioenergetic stress

Glucose deprivation activates AMPK and induces cell death through modulation of Akt in ovarian cancer cells

(2011) Anna Priebe et al.   GYNECOLOGIC ONCOLOGY

Transformation of rat intestinal epithelial cells by overexpression of Rab25 is microtubule dependent

(2010) Lynne A. Lapierre et al.   Cytoskeleton

Loss of Rab25 promotes the development of intestinal neoplasia in mice and is associated with human colorectal adenocarcinomas

(2010) Ki Taek Nam et al.   JOURNAL OF CLINICAL INVESTIGATION

GTPases involved in vesicular trafficking: Structures and mechanisms

(2010) Aymelt Itzen et al.   SEMINARS IN CELL & DEVELOPMENTAL BIOLOGY

The paradox of autophagy and its implication in cancer etiology and therapy

(2009) Avital Eisenberg-Lerner et al.   APOPTOSIS

Akt-dependent and -independent mechanisms of mTOR regulation in cancer

(2009) Regan M. Memmott et al.   CELLULAR SIGNALLING

The molecular determinants of de novo nucleotide biosynthesis in cancer cells

(2009) Xuemei Tong et al.   CURRENT OPINION IN GENETICS & DEVELOPMENT

The tale of transforming growth factor-beta (TGFβ) signaling: A soigné enigma

(2009) Arindam Chaudhury et al.   IUBMB LIFE

The Glycolytic Inhibitor 2-Deoxyglucose Activates Multiple Prosurvival Pathways through IGF1R

(2009) Diansheng Zhong et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Akt and c-Myc Differentially Activate Cellular Metabolic Programs and Prime Cells to Bioenergetic Inhibition

(2009) Yongjun Fan et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Glucose deprivation-induced metabolic oxidative stress and cancer therapy

(2009) DouglasR Spitz et al.   Journal of Cancer Research and Therapeutics

The recycling and transcytotic pathways for IgG transport by FcRn are distinct and display an inherent polarity

(2009) Salit Tzaban et al.   JOURNAL OF CELL BIOLOGY

Understanding the Warburg Effect: The Metabolic Requirements of Cell Proliferation

(2009) M. G. Vander Heiden et al.   SCIENCE

The Emerging Role of the RAB25 Small GTPase in Cancer

(2009) Roshan Agarwal et al.   TRAFFIC

Intrinsically lower AKT, mammalian target of rapamycin, and hypoxia-inducible factor activity correlates with increased sensitivity to 2-deoxy-d-glucose under hypoxia in lung cancer cell lines

(2008) Medhi Wangpaichitr et al.   MOLECULAR CANCER THERAPEUTICS

2-Deoxyglucose induces Akt phosphorylation via a mechanism independent of LKB1/AMP-activated protein kinase signaling activation or glycolysis inhibition

(2008) D. Zhong et al.   MOLECULAR CANCER THERAPEUTICS

A catabolic block does not sufficiently explain how 2-deoxy-D-glucose inhibits cell growth

(2008) M. Ralser et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA