5-HT6receptor recruitment of mTOR as a mechanism for perturbed cognition in schizophrenia

mTOR Signaling in Growth Control and Disease

(2012) Mathieu Laplante et al.   CELL

Cognitive dysfunction in psychiatric disorders: characteristics, causes and the quest for improved therapy

(2012) Mark J. Millan et al.   NATURE REVIEWS DRUG DISCOVERY

Animal models of schizophrenia

(2011) CA Jones et al.   BRITISH JOURNAL OF PHARMACOLOGY

5-HT6 receptor and cognition

(2011) Xabier Codony et al.   CURRENT OPINION IN PHARMACOLOGY

Mutations causing syndromic autism define an axis of synaptic pathophysiology

(2011) Benjamin D. Auerbach et al.   NATURE

Rhes, a striatal-enriched small G protein, mediates mTOR signaling and L-DOPA–induced dyskinesia

(2011) Srinivasa Subramaniam et al.   NATURE NEUROSCIENCE

Influence of social isolation in the rat on serotonergic function and memory – Relevance to models of schizophrenia and the role  of 5-HT6 receptors

(2011) Charles A. Marsden et al.   NEUROPHARMACOLOGY

The Complexes of Mammalian Target of Rapamycin

(2010) Hongyu Zhou et al.   CURRENT PROTEIN & PEPTIDE SCIENCE

Tti1 and Tel2 Are Critical Factors in Mammalian Target of Rapamycin Complex Assembly

(2010) Takeshi Kaizuka et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Rethinking schizophrenia

(2010) Thomas R. Insel   NATURE

Huntington’s Disease is a disorder of the corpus striatum: Focus on Rhes (Ras homologue enriched in the striatum)

(2010) Srinivasa Subramaniam et al.   NEUROPHARMACOLOGY

Rapamycin for treating Tuberous sclerosis and Autism spectrum disorders

(2010) Dan Ehninger et al.   TRENDS IN MOLECULAR MEDICINE

mTORC1 signaling: what we still don't know

(2010) X. Wang et al.   Journal of Molecular Cell Biology

Inhibition of mTOR Signaling in Parkinson's Disease Prevents L-DOPA-Induced Dyskinesia

(2009) E. Santini et al.   Science Signaling

Effects of 5-HT6 receptor antagonism and cholinesterase inhibition in models of cognitive impairment in the rat

(2008) B Marcos et al.   BRITISH JOURNAL OF PHARMACOLOGY

Reversal of learning deficits in a Tsc2 +/− mouse model of tuberous sclerosis

(2008) Dan Ehninger et al.   NATURE MEDICINE

Behavioural and neurochemical effects of post-weaning social isolation in rodents—Relevance to developmental neuropsychiatric disorders

(2008) Kevin C.F. Fone et al.   NEUROSCIENCE AND BIOBEHAVIORAL REVIEWS

Signaling at G-protein-coupled serotonin receptors: recent advances and future research directions

(2008) M MILLAN et al.   TRENDS IN PHARMACOLOGICAL SCIENCES

Role of mTOR in physiology and pathology of the nervous system

(2007) Lukasz Swiech et al.   BIOCHIMICA ET BIOPHYSICA ACTA-PROTEINS AND PROTEOMICS