MicroRNA-146a-mediated downregulation of IRAK1 protects mouse and human small intestine against ischemia/reperfusion injury

Depletion of gut commensal bacteria attenuates intestinal ischemia/reperfusion injury

(2011) Kazuhisa Yoshiya et al.   AMERICAN JOURNAL OF PHYSIOLOGY-GASTROINTESTINAL AND LIVER PHYSIOLOGY

Mechanism of hypoxia-induced NFκB

(2011) Andrew Melvin et al.   CELL CYCLE

Enhancement of proteasomal function protects against cardiac proteinopathy and ischemia/reperfusion injury in mice

(2011) Jie Li et al.   JOURNAL OF CLINICAL INVESTIGATION

miR-146ais a significant brake on autoimmunity, myeloproliferation, and cancer in mice

(2011) Mark P. Boldin et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Hypoxia-Inducible Factor-1α–Dependent Protection from Intestinal Ischemia/Reperfusion Injury Involves Ecto-5′-Nucleotidase (CD73) and the A2B Adenosine Receptor

(2011) Melanie L. Hart et al.   JOURNAL OF IMMUNOLOGY

Crosstalk between B lymphocytes, microbiota and the intestinal epithelium governs immunity versus metabolism in the gut

(2011) Natalia Shulzhenko et al.   NATURE MEDICINE

miR-146a Suppresses Invasion of Pancreatic Cancer Cells

(2010) Y. Li et al.   CANCER RESEARCH

Heat shock protein gp96 and NAD(P)H oxidase 4 play key roles in Toll-like receptor 4-activated apoptosis during renal ischemia/reperfusion injury

(2010) S Ben Mkaddem et al.   CELL DEATH AND DIFFERENTIATION

miR-146a Mediates Protective Innate Immune Tolerance in the Neonate Intestine

(2010) Cécilia Chassin et al.   Cell Host & Microbe

Enterocyte-specific A20 deficiency sensitizes to tumor necrosis factor–induced toxicity and experimental colitis

(2010) Lars Vereecke et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Hydroxylase Inhibition Abrogates TNF- -Induced Intestinal Epithelial Damage by Hypoxia-Inducible Factor-1-Dependent Repression of FADD

(2010) P. Hindryckx et al.   JOURNAL OF IMMUNOLOGY

Complement regulates TLR4-mediated inflammatory responses during intestinal ischemia reperfusion

(2010) Michael R. Pope et al.   MOLECULAR IMMUNOLOGY

Hypoxia: an alarm signal during intestinal inflammation

(2010) Sean P. Colgan et al.   Nature Reviews Gastroenterology & Hepatology

The SUMO pathway: emerging mechanisms that shape specificity, conjugation and recognition

(2010) Jaclyn R. Gareau et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Identification of a microRNA signature of renal ischemia reperfusion injury

(2010) J. G. Godwin et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Novel critical role of Toll-like receptor 4 in lung ischemia-reperfusion injury and edema

(2009) Giorgio Zanotti et al.   AMERICAN JOURNAL OF PHYSIOLOGY-LUNG CELLULAR AND MOLECULAR PHYSIOLOGY

Origins and Mechanisms of miRNAs and siRNAs

(2009) Richard W. Carthew et al.   CELL

Toll-like receptor 9 inhibition confers protection from liver ischemia-reperfusion injury

(2009) Zubin M. Bamboat et al.   HEPATOLOGY

Somatostatin Limits Intestinal Ischemia-Reperfusion Injury in Macaques via Suppression of TLR4-NF-κB Cytokine Pathway

(2009) Hao Wu et al.   JOURNAL OF GASTROINTESTINAL SURGERY

TLR4-mediated Cox-2 expression increases intestinal ischemia/reperfusion-induced damage

(2009) Tiffany Moses et al.   JOURNAL OF LEUKOCYTE BIOLOGY

Toll-like receptor 4 is a key mediator of murine steatotic liver warm ischemia/reperfusion injury

(2009) Justin D. Ellett et al.   LIVER TRANSPLANTATION

Ubiquitin Chain Editing Revealed by Polyubiquitin Linkage-Specific Antibodies

(2008) Kim Newton et al.   CELL

c-Jun NH2-terminal kinase (JNK)-dependent nuclear translocation of apoptosis-inducing factor (AIF) following engagement of membrane immunoglobulin on WEHI-231 B lymphoma cells

(2008) Eiko Takada et al.   JOURNAL OF CELLULAR BIOCHEMISTRY

Homeostatic MyD88-dependent signals cause lethal inflamMation in the absence of A20

(2008) Emre E. Turer et al.   JOURNAL OF EXPERIMENTAL MEDICINE

The Novel NF-κB Inhibitor, Dehydroxymethylepoxyquinomicin, Prevents Local and Remote Organ Injury Following Intestinal Ischemia/Reperfusion in Rats

(2008) Tomomi Suzuki et al.   JOURNAL OF SURGICAL RESEARCH

Interleukin-1 (IL-1) Induces the Lys63-Linked Polyubiquitination of IL-1 Receptor-Associated Kinase 1 To Facilitate NEMO Binding and the Activation of I B  Kinase

(2008) M. Windheim et al.   MOLECULAR AND CELLULAR BIOLOGY

Intestinal Ischemia/Reperfusion Injury Triggers Activation of Innate Toll-Like Receptor 4 and Adaptive Chemokine Programs

(2008) M.J. Watson et al.   TRANSPLANTATION PROCEEDINGS

IRAK1: A critical signaling mediator of innate immunity

(2007) Sridevi Gottipati et al.   CELLULAR SIGNALLING

The Hydroxylase Inhibitor Dimethyloxalylglycine Is Protective in a Murine Model of Colitis

(2007) Eoin P. Cummins et al.   GASTROENTEROLOGY

Mucosal Protection by Hypoxia-Inducible Factor Prolyl Hydroxylase Inhibition

(2007) Andreas Robinson et al.   GASTROENTEROLOGY