Preventing acute gut wall damage in infectious diarrhoeas with glycosylated dendrimers

Differential Activation of Human TLR4 by Escherichia coli and Shigella flexneri 2a Lipopolysaccharide: Combined Effects of Lipid A Acylation State and TLR4 Polymorphisms on Signaling

(2014) P. Rallabhandi et al.   JOURNAL OF IMMUNOLOGY

NMR Studies of Hexaacylated Endotoxin Bound to Wild-type and F126A Mutant MD-2 and MD-2·TLR4 Ectodomain Complexes

(2012) Liping Yu et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Quantitative RT-PCR profiling of the Rabbit Immune Response: Assessment of Acute Shigella flexneri Infection

(2012) Pamela Schnupf et al.   PLoS One

Structural basis of species-specific endotoxin sensing by innate immune receptor TLR4/MD-2

(2012) U. Ohto et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Dendrimer-Based Postnatal Therapy for Neuroinflammation and Cerebral Palsy in a Rabbit Model

(2012) S. Kannan et al.   Science Translational Medicine

Accelerated healing of cutaneous leishmaniasis in non-healing BALB/c mice using water soluble amphotericin B-polymethacrylic acid

(2011) Karina Corware et al.   BIOMATERIALS

Computational design principles for bioactive dendrimer based constructs as antagonists of the TLR4-MD-2-LPS complex

(2011) Teresa Barata et al.   BIOMATERIALS

TLR Signaling Is Required for Salmonella typhimurium Virulence

(2011) Nicholas Arpaia et al.   CELL

The Shigella flexneri Type Three Secretion System Effector IpgD Inhibits T Cell Migration by Manipulating Host Phosphoinositide Metabolism

(2011) Christoph Konradt et al.   Cell Host & Microbe

Wound Healing Versus Regeneration: Role of the Tissue Environment in Regenerative Medicine

(2011) Anthony Atala et al.   MRS BULLETIN

Innate immunity cues virulence

(2011) Michelle M. C. Buckner et al.   NATURE

Bacteria and host interactions in the gut epithelial barrier

(2011) Hiroshi Ashida et al.   Nature Chemical Biology

German Outbreak ofEscherichia coliO104:H4 Associated with Sprouts

(2011) Udo Buchholz et al.   NEW ENGLAND JOURNAL OF MEDICINE

   intraepithelial lymphocytes are essential mediators of host-microbial homeostasis at the intestinal mucosal surface

(2011) A. S. Ismail et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

A Phosphorus-Based Dendrimer Targets Inflammation and Osteoclastogenesis in Experimental Arthritis

(2011) M. Hayder et al.   Science Translational Medicine

Gadd45α activity is the principal effector of Shigella mitochondria-dependent epithelial cell death in vitro and ex vivo

(2011) L Lembo-Fazio et al.   Cell Death & Disease

Partially Glycosylated Dendrimers Block MD-2 and Prevent TLR4-MD-2-LPS Complex Mediated Cytokine Responses

(2011) Teresa S. Barata et al.   PLoS Computational Biology

A Role for TLR4 in Clostridium difficile Infection and the Recognition of Surface Layer Proteins

(2011) Anthony Ryan et al.   PLoS Pathogens

Shigellosis update: advancing antibiotic resistance, investment empowered vaccine development, and green bananas

(2010) Margaret Kosek et al.   CURRENT OPINION IN INFECTIOUS DISEASES

Dendrimer-based drug and imaging conjugates: design considerations for nanomedical applications

(2010) Anupa R. Menjoge et al.   DRUG DISCOVERY TODAY

Poly propyl ether imine (PETIM) dendrimer: A novel non-toxic dendrimer for sustained drug delivery

(2010) Subheet Jain et al.   EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY

Th17 Cells Are the Dominant T Cell Subtype Primed by Shigella flexneri Mediating Protective Immunity

(2010) Gernot Sellge et al.   JOURNAL OF IMMUNOLOGY

Structural studies of biologically active glycosylated polyamidoamine (PAMAM) dendrimers

(2010) Teresa Silva Barata et al.   JOURNAL OF MOLECULAR MODELING

Advances in the Elegance of Chemistry in Designing Dendrimers

(2010) Rami Hourani et al.   MACROMOLECULAR RAPID COMMUNICATIONS

Regulatory Lymphocytes and Intestinal Inflammation

(2009) Ana Izcue et al.   Annual Review of Immunology

Campylobacter jejuni-Induced Activation of Dendritic Cells Involves Cooperative Signaling through Toll-Like Receptor 4 (TLR4)-MyD88 and TLR4-TRIF Axes

(2009) V. A. K. Rathinam et al.   INFECTION AND IMMUNITY

Reciprocal Interactions between Commensal Bacteria and    Intraepithelial Lymphocytes during Mucosal Injury

(2009) A. S. Ismail et al.   JOURNAL OF IMMUNOLOGY

Semiquantitative Study of the EDC/NHS Activation of Acid Terminal Groups at Modified Porous Silicon Surfaces

(2009) S. Sam et al.   LANGMUIR

Electrophoretic Behavior of Anionic Triazine and PAMAM Dendrimers: Methods for Improving Resolution and Assessing Purity Using Capillary Electrophoresis

(2009) Sanjiv Lalwani et al.   MACROMOLECULES

Mimicking PAMAM Dendrimers with Amphoteric, Hybrid Triazine Dendrimers: A Comparison of Dispersity and Stability

(2009) Sanjiv Lalwani et al.   MACROMOLECULES

The structural basis of lipopolysaccharide recognition by the TLR4–MD-2 complex

(2009) Beom Seok Park et al.   NATURE

The gut feeling of Treg cells: IL-10 is the silver lining during colitis

(2009) Derya Unutmaz et al.   NATURE IMMUNOLOGY

Interleukin 10 acts on regulatory T cells to maintain expression of the transcription factor Foxp3 and suppressive function in mice with colitis

(2009) Masako Murai et al.   NATURE IMMUNOLOGY

Characterisation of Early Mucosal and Neuronal Lesions Following Shigella flexneri Infection in Human Colon

(2009) Emmanuel Coron et al.   PLoS One

VirulentShigella flexnerisubverts the host innate immune response through manipulation of antimicrobial peptide gene expression

(2008) Brice Sperandio et al.   JOURNAL OF EXPERIMENTAL MEDICINE