Morphine-induced mu opioid receptor trafficking enhances reward yet prevents compulsive drug use

Acute withdrawal, protracted abstinence and negative affect in alcoholism: are they linked?

(2010) Markus Heilig et al.   ADDICTION BIOLOGY

Agonist-dependent μ-opioid receptor signaling can lead to heterologous desensitization

(2010) Ji Chu et al.   CELLULAR SIGNALLING

Regulation of opioid receptors by endocytic membrane traffic: Mechanisms and translational implications

(2010) Mark von Zastrow   DRUG AND ALCOHOL DEPENDENCE

 -Opioid Receptor Endocytosis Prevents Adaptations in Ventral Tegmental Area GABA Transmission Induced during Naloxone-Precipitated Morphine Withdrawal

(2010) A. Madhavan et al.   JOURNAL OF NEUROSCIENCE

Teaching old receptors new tricks: biasing seven-transmembrane receptors

(2010) Sudarshan Rajagopal et al.   NATURE REVIEWS DRUG DISCOVERY

Compulsive alcohol drinking in rodents

(2009) Valentina Vengeliene et al.   ADDICTION BIOLOGY

Predictors of buprenorphine–naloxone dosing in a 12-week treatment trial for opioid-dependent youth: Secondary analyses from a NIDA Clinical Trials Network study☆

(2009) Amit Chakrabarti et al.   DRUG AND ALCOHOL DEPENDENCE

Biomarkers of morphine tolerance and dependence are prevented by morphine-induced endocytosis of a mutant μ-opioid receptor

(2009) Li He et al.   FASEB JOURNAL

Stress and addiction: glucocorticoid receptor in dopaminoceptive neurons facilitates cocaine seeking

(2009) Frédéric Ambroggi et al.   NATURE NEUROSCIENCE

Neurocircuitry of Addiction

(2009) George F Koob et al.   NEUROPSYCHOPHARMACOLOGY

Pattern of Intake and Drug Craving Predict the Development of Cocaine Addiction-like Behavior in Rats

(2008) David Belin et al.   BIOLOGICAL PSYCHIATRY

Morphine-Induced Receptor Endocytosis in a Novel Knockin Mouse Reduces Tolerance and Dependence

(2008) Joseph A. Kim et al.   CURRENT BIOLOGY

Predictors of outcome for short-term medically supervised opioid withdrawal during a randomized, multicenter trial of buprenorphine–naloxone and clonidine in the NIDA clinical trials network drug and alcohol dependence

(2008) Douglas M. Ziedonis et al.   DRUG AND ALCOHOL DEPENDENCE

Retrospective accounts of initial subjective effects of opioids in patients treated for pain who do or do not develop opioid addiction: A pilot case-control study.

(2008) Corey M. Bieber et al.   EXPERIMENTAL AND CLINICAL PSYCHOPHARMACOLOGY

Neural mechanisms underlying the vulnerability to develop compulsive drug-seeking habits and addiction

(2008) B. J Everitt et al.   PHILOSOPHICAL TRANSACTIONS OF THE ROYAL SOCIETY B-BIOLOGICAL SCIENCES

Agonist-selective mechanisms of GPCR desensitization

(2007) E Kelly et al.   BRITISH JOURNAL OF PHARMACOLOGY