Journal
EMBO JOURNAL
Volume 33, Issue 18, Pages 1984-1986Publisher
WILEY-BLACKWELL
DOI: 10.15252/embj.201489479
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Heterogeneity within tumors is becoming increasingly recognized as an important cause of treatment failure in cancer. Two recent studies use fate-mapping and limiting dilution transplantation assays to identify SRY (sex determining region Y)-box 2 (Sox2) as cancer stem-cell marker and driver of cancer stemness.
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