Allosteric regulation of E2:E3 interactions promote a processive ubiquitination machine

Structure of a Ubiquitin E1-E2 Complex: Insights to E1-E2 Thioester Transfer

(2013) Shaun K. Olsen et al.   MOLECULAR CELL

A Structurally Unique E2-Binding Domain Activates Ubiquitination by the ERAD E2, Ubc7p, through Multiple Mechanisms

(2013) Meredith B. Metzger et al.   MOLECULAR CELL

Using chemical shift perturbation to characterise ligand binding

(2013) Mike P. Williamson   PROGRESS IN NUCLEAR MAGNETIC RESONANCE SPECTROSCOPY

HECT and RING finger families of E3 ubiquitin ligases at a glance

(2012) M. B. Metzger et al.   JOURNAL OF CELL SCIENCE

Structure of an E3:E2∼Ub Complex Reveals an Allosteric Mechanism Shared among RING/U-box Ligases

(2012) Jonathan N. Pruneda et al.   MOLECULAR CELL

Structure of a RING E3 ligase and ubiquitin-loaded E2 primed for catalysis

(2012) Anna Plechanovová et al.   NATURE

BIRC7–E2 ubiquitin conjugate structure reveals the mechanism of ubiquitin transfer by a RING dimer

(2012) Hao Dou et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

The Delicate Balance Between Secreted Protein Folding and Endoplasmic Reticulum-Associated Degradation in Human Physiology

(2012) Christopher J. Guerriero et al.   PHYSIOLOGICAL REVIEWS

Insights into ubiquitin-conjugating enzyme/ co-activator interactions from the structure of the Pex4p:Pex22p complex

(2011) Chris Williams et al.   EMBO JOURNAL

E3 ligase Rad18 promotes monoubiquitination rather than ubiquitin chain formation by E2 enzyme Rad6

(2011) R. G. Hibbert et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Ancient Ubiquitous Protein 1 (AUP1) Localizes to Lipid Droplets and Binds the E2 Ubiquitin Conjugase G2 (Ube2g2) via Its G2 Binding Region

(2010) Johanna Spandl et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

The N Terminus of Cbl-c Regulates Ubiquitin Ligase Activity by Modulating Affinity for the Ubiquitin-conjugating Enzyme

(2010) Philip E. Ryan et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

The Diversity of Ubiquitin Recognition: Hot Spots and Varied Specificity

(2010) Jason M. Winget et al.   MOLECULAR CELL

The HADDOCK web server for data-driven biomolecular docking

(2010) Sjoerd J de Vries et al.   Nature Protocols

Tautomeric states of the active-site histidines of phosphorylated and unphosphorylated IIIGlc, a signal-transducing protein from escherichia coli, using two-dimensional heteronuclear NMR techniques

(2010) J.G. Pelton et al.   PROTEIN SCIENCE

RING Domain E3 Ubiquitin Ligases

(2009) Raymond J. Deshaies et al.   Annual Review of Biochemistry

Rapid E2-E3 Assembly and Disassembly Enable Processive Ubiquitylation of Cullin-RING Ubiquitin Ligase Substrates

(2009) Gary Kleiger et al.   CELL

A Ubc7p-binding domain in Cue1p activates ER-associated protein degradation

(2009) Z. Kostova et al.   JOURNAL OF CELL SCIENCE

Allosteric Activation of E2-RING Finger-Mediated Ubiquitylation by a Structurally Defined Specific E2-Binding Region of gp78

(2009) Ranabir Das et al.   MOLECULAR CELL

Mechanistic insights into active site-associated polyubiquitination by the ubiquitin-conjugating enzyme Ube2g2

(2009) W. Li et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Solution structure and dynamics of human ubiquitin conjugating enzyme Ube2g2

(2009) Tingting Ju et al.   PROTEINS-STRUCTURE FUNCTION AND BIOINFORMATICS