pRb is an obesity suppressor in hypothalamus and high-fat diet inhibits pRb in this location

IKKβ/NF-κB disrupts adult hypothalamic neural stem cells to mediate a neurodegenerative mechanism of dietary obesity and pre-diabetes

(2012) Juxue Li et al.   NATURE CELL BIOLOGY

Tanycytes of the hypothalamic median eminence form a diet-responsive neurogenic niche

(2012) Daniel A Lee et al.   NATURE NEUROSCIENCE

Remodeling of the arcuate nucleus energy-balance circuit is inhibited in obese mice

(2011) David E.G. McNay et al.   JOURNAL OF CLINICAL INVESTIGATION

Obesity is associated with hypothalamic injury in rodents and humans

(2011) Joshua P. Thaler et al.   JOURNAL OF CLINICAL INVESTIGATION

Differential gene expression between neuropeptide Y expressing neurons of the dorsomedial nucleus of the Hypothalamus and the Arcuate Nucleus: Microarray Analysis Study

(2010) Shin Draper et al.   BRAIN RESEARCH

Pomc-expressing progenitors give rise to antagonistic neuronal populations in hypothalamic feeding circuits

(2010) Stephanie L Padilla et al.   NATURE MEDICINE

AMP-Activated Protein Kinase Phosphorylates Retinoblastoma Protein to Control Mammalian Brain Development

(2009) Biplab Dasgupta et al.   DEVELOPMENTAL CELL

Skp2 is required for survival of aberrantly proliferating Rb1-deficient cells and for tumorigenesis in Rb1+/− mice

(2009) Hongbo Wang et al.   NATURE GENETICS

High-Fat Diet Induces Apoptosis of Hypothalamic Neurons

(2009) Juliana C. Moraes et al.   PLoS One

An E2F1-Dependent Gene Expression Program that Determines the Balance between Proliferation and Cell Death

(2008) Timothy C. Hallstrom et al.   CANCER CELL

Hypothalamic Neural Projections Are Permanently Disrupted in Diet-Induced Obese Rats

(2008) Sebastien G. Bouret et al.   Cell Metabolism

Hypothalamic CaMKK2 Contributes to the Regulation of Energy Balance

(2008) Kristin A. Anderson et al.   Cell Metabolism

Synaptic release of GABA by AgRP neurons is required for normal regulation of energy balance

(2008) Qingchun Tong et al.   NATURE NEUROSCIENCE

High-resolution in situ hybridization to whole-mount zebrafish embryos

(2007) Christine Thisse et al.   Nature Protocols