Impairment of GABAB receptor dimer by endogenous 14-3-3ζ in chronic pain conditions

The oligomeric state sets GABABreceptor signalling efficacy

(2011) Laëtitia Comps-Agrar et al.   EMBO JOURNAL

Intrinsic membrane properties of spinal dorsal horn neurones modulate nociceptive information processingin vivo

(2011) Cecilia Reali et al.   JOURNAL OF PHYSIOLOGY-LONDON

p38/MAPK Inhibitor Modulates the Expression of Dorsal Horn GABA(B) Receptors in the Spinal Nerve Ligation Model of Neuropathic Pain

(2011) Junzhen Wu et al.   NEUROIMMUNOMODULATION

Dimers and beyond: The functional puzzles of class C GPCRs

(2011) Julie Kniazeff et al.   PHARMACOLOGY & THERAPEUTICS

Trans-activation between 7TM domains: implication in heterodimeric GABABreceptor activation

(2010) Carine Monnier et al.   EMBO JOURNAL

Native GABAB receptors are heteromultimers with a family of auxiliary subunits

(2010) Jochen Schwenk et al.   NATURE

Modulation of inhibitory neurotransmission by the vanilloid receptor type 1 (TRPV1) in organotypically cultured mouse substantia gelatinosa neurons

(2010) Francesco Ferrini et al.   PAIN

Physiological relevance of GPCR oligomerization and its impact on drug discovery

(2008) Rosemarie Panetta et al.   DRUG DISCOVERY TODAY

The Availability of Surface GABABReceptors Is Independent of γ-Aminobutyric Acid but Controlled by Glutamate in Central Neurons

(2008) Karina J. Vargas et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Dimerization and oligomerization of G-protein-coupled receptors: debated structures with established and emerging functions

(2008) László Szidonya et al.   JOURNAL OF ENDOCRINOLOGY

Depletion of 14-3-3 zeta elicits endoplasmic reticulum stress and cell death, and increases vulnerability to kainate-induced injury in mouse hippocampal cultures

(2008) Niamh Murphy et al.   JOURNAL OF NEUROCHEMISTRY

Constitutive, agonist-accelerated, recycling and lysosomal degradation of GABAB receptors in cortical neurons

(2008) Thomas Grampp et al.   MOLECULAR AND CELLULAR NEUROSCIENCE

Reversal of pathological pain through specific spinal GABAA receptor subtypes

(2008) Julia Knabl et al.   NATURE

Identification of a serotonin/glutamate receptor complex implicated in psychosis

(2008) Javier González-Maeso et al.   NATURE

Structural diversity of G protein-coupled receptors and significance for drug discovery

(2008) Malin C. Lagerström et al.   NATURE REVIEWS DRUG DISCOVERY

GPCR monomers and oligomers: it takes all kinds

(2008) Vsevolod V. Gurevich et al.   TRENDS IN NEUROSCIENCES