PABP is not essential for microRNA-mediated translational repression and deadenylationin vitro

GW182 Proteins Directly Recruit Cytoplasmic Deadenylase Complexes to miRNA Targets

(2011) Joerg E. Braun et al.   MOLECULAR CELL

miRNA-mediated deadenylation is orchestrated by GW182 through two conserved motifs that interact with CCR4–NOT

(2011) Marc R Fabian et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

miRNA repression involves GW182-mediated recruitment of CCR4–NOT through conserved W-containing motifs

(2011) Marina Chekulaeva et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

Two PABPC1-binding sites in GW182 proteins promote miRNA-mediated gene silencing

(2010) Eric Huntzinger et al.   EMBO JOURNAL

CCR4-NOT Deadenylates mRNA Associated with RNA-Induced Silencing Complexes in Human Cells

(2010) X. Piao et al.   MOLECULAR AND CELLULAR BIOLOGY

Structural insights into the human GW182-PABC interaction in microRNA-mediated deadenylation

(2010) Martin Jinek et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

Divergent GW182 functional domains in the regulation of translational silencing

(2010) Bing Yao et al.   NUCLEIC ACIDS RESEARCH

The GW/WG repeats of Drosophila GW182 function as effector motifs for miRNA-mediated repression

(2010) Marina Chekulaeva et al.   NUCLEIC ACIDS RESEARCH

Mechanism of translational regulation by miR-2 from sites in the 5' untranslated region or the open reading frame

(2010) F. Moretti et al.   RNA

Making RISC

(2010) Tomoko Kawamata et al.   TRENDS IN BIOCHEMICAL SCIENCES

Repression of C. elegans microRNA targets at the initiation level of translation requires GW182 proteins

(2009) Xavier C Ding et al.   EMBO JOURNAL

Functional Dissection of the Human TNRC6 (GW182-Related) Family of Proteins

(2009) D. Baillat et al.   MOLECULAR AND CELLULAR BIOLOGY

The Silencing Domain of GW182 Interacts with PABPC1 To Promote Translational Repression and Degradation of MicroRNA Targets and Is Required for Target Release

(2009) L. Zekri et al.   MOLECULAR AND CELLULAR BIOLOGY

The Chicken or the Egg: MicroRNA-Mediated Regulation of mRNA Translation or mRNA Stability

(2009) Arina D. Omer et al.   MOLECULAR CELL

Drosophila miR2 Primarily Targets the m7GpppN Cap Structure for Translational Repression

(2009) Agnieszka Zdanowicz et al.   MOLECULAR CELL

Mammalian miRNA RISC Recruits CAF1 and PABP to Affect PABP-Dependent Deadenylation

(2009) Marc R. Fabian et al.   MOLECULAR CELL

Drosophila Argonaute1 and Argonaute2 Employ Distinct Mechanisms for Translational Repression

(2009) Shintaro Iwasaki et al.   MOLECULAR CELL

The SXL-UNR Corepressor Complex Uses a PABP-Mediated Mechanism to Inhibit Ribosome Recruitment to msl-2 mRNA

(2009) Kent E. Duncan et al.   MOLECULAR CELL

Ago–TNRC6 triggers microRNA-mediated decay by promoting two deadenylation steps

(2009) Chyi-Ying A Chen et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

Structural determinants of miRNAs for RISC loading and slicer-independent unwinding

(2009) Tomoko Kawamata et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

microRNA-Mediated Messenger RNA Deadenylation Contributes to Translational Repression in Mammalian Cells

(2009) Traude H. Beilharz et al.   PLoS One

Importance of the C-terminal domain of the human GW182 protein TNRC6C for translational repression

(2009) J. T. Zipprich et al.   RNA

Multiple independent domains of dGW182 function in miRNA-mediated repression in Drosophila

(2009) M. Chekulaeva et al.   RNA

Mammalian GW182 contains multiple Argonaute-binding sites and functions in microRNA-mediated translational repression

(2009) K. Takimoto et al.   RNA

The C-terminal half of human Ago2 binds to multiple GW-rich regions of GW182 and requires GW182 to mediate silencing

(2009) S. L. Lian et al.   RNA

A C-terminal silencing domain in GW182 is essential for miRNA function

(2009) A. Eulalio et al.   RNA

The C-terminal domains of human TNRC6A, TNRC6B, and TNRC6C silence bound transcripts independently of Argonaute proteins

(2009) D. Lazzaretti et al.   RNA

Argonaute Loading Improves the 5′ Precision of Both MicroRNAs and Their miRNA∗ Strands in Flies

(2008) Hervé Seitz et al.   CURRENT BIOLOGY

Drosophila endogenous small RNAs bind to Argonaute 2 in somatic cells

(2008) Yoshinori Kawamura et al.   NATURE

An endogenous small interfering RNA pathway in Drosophila

(2008) Benjamin Czech et al.   NATURE

GW182 interaction with Argonaute is essential for miRNA-mediated translational repression and mRNA decay

(2008) Ana Eulalio et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

Computational analysis of miRNA-mediated repression of translation: Implications for models of translation initiation inhibition

(2008) T. Nissan et al.   RNA

Deadenylation is a widespread effect of miRNA regulation

(2008) A. Eulalio et al.   RNA

Endogenous siRNAs Derived from Transposons and mRNAs in Drosophila Somatic Cells

(2008) M. Ghildiyal et al.   SCIENCE