Misfolded PrP impairs the UPS by interaction with the 20S proteasome and inhibition of substrate entry
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Title
Misfolded PrP impairs the UPS by interaction with the 20S proteasome and inhibition of substrate entry
Authors
Keywords
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Journal
EMBO JOURNAL
Volume 30, Issue 15, Pages 3065-3077
Publisher
Wiley
Online
2011-07-08
DOI
10.1038/emboj.2011.224
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Related references
Note: Only part of the references are listed.- Expression of Mutant or Cytosolic PrP in Transgenic Mice and Cells Is Not Associated with Endoplasmic Reticulum Stress or Proteasome Dysfunction
- (2011) Elena Quaglio et al. PLoS One
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- (2010) Z. Ortega et al. JOURNAL OF NEUROSCIENCE
- Variably modulated gating of the 26S proteasome by ATP and polyubiquitin
- (2009) Xiaohua Li et al. BIOCHEMICAL JOURNAL
- Isolation of Mammalian 26S Proteasomes and p97/VCP Complexes Using the Ubiquitin-like Domain from HHR23B Reveals Novel Proteasome-Associated Proteins†
- (2009) Henrike C. Besche et al. BIOCHEMISTRY
- Interactions of PAN's C-termini with archaeal 20S proteasome and implications for the eukaryotic proteasome–ATPase interactions
- (2009) Yadong Yu et al. EMBO JOURNAL
- Ubiquitinated Proteins Activate the Proteasome by Binding to Usp14/Ubp6, which Causes 20S Gate Opening
- (2009) Andreas Peth et al. MOLECULAR CELL
- Polyubiquitin substrates allosterically activate their own degradation by the 26S proteasome
- (2009) Dawadschargal Bech-Otschir et al. NATURE STRUCTURAL & MOLECULAR BIOLOGY
- A Tetrahedral Transition State at the Active Sites of the 20S Proteasome Is Coupled to Opening of the α-Ring Channel
- (2009) Pawel A. Osmulski et al. STRUCTURE
- HECTD2 Is Associated with Susceptibility to Mouse and Human Prion Disease
- (2009) Sarah E. Lloyd et al. PLoS Genetics
- Prions and the proteasome
- (2008) Pelagia Deriziotis et al. BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE
- Bortezomib arrests the proliferation of hepatocellular carcinoma cells HepG2 and JHH6 by differentially affecting E2F1, p21 and p27 levels
- (2008) Daniele Baiz et al. BIOCHIMIE
- Differential Roles of the COOH Termini of AAA Subunits of PA700 (19 S Regulator) in Asymmetric Assembly and Activation of the 26 S Proteasome
- (2008) Thomas G. Gillette et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Depletion of 26S Proteasomes in Mouse Brain Neurons Causes Neurodegeneration and Lewy-Like Inclusions Resembling Human Pale Bodies
- (2008) L. Bedford et al. JOURNAL OF NEUROSCIENCE
- Mechanism of Gate Opening in the 20S Proteasome by the Proteasomal ATPases
- (2008) Julius Rabl et al. MOLECULAR CELL
- Aβ inhibits the proteasome and enhances amyloid and tau accumulation
- (2007) Bertrand P. Tseng et al. NEUROBIOLOGY OF AGING
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