Mechanisms and dynamics of AKAP79/150-orchestrated multi-protein signalling complexes in brain and peripheral nerve

Differential regulation of CaV1.2 channels by cAMP-dependent protein kinase bound to A-kinase anchoring proteins 15 and 79/150

(2014) Matthew D. Fuller et al.   JOURNAL OF GENERAL PHYSIOLOGY

Pivoting between Calmodulin Lobes Triggered by Calcium in the Kv7.2/Calmodulin Complex

(2014) Alessandro Alaimo et al.   PLoS One

AKAP-Anchored PKA Maintains Neuronal L-type Calcium Channel Activity and NFAT Transcriptional Signaling

(2014) Jonathan G. Murphy et al.   Cell Reports

Ca 2+ /Calcineurin-Dependent Inactivation of Neuronal L-Type Ca 2+ Channels Requires Priming by AKAP-Anchored Protein Kinase A

(2014) Philip J. Dittmer et al.   Cell Reports

AKAP150 Contributes to Enhanced Vascular Tone by Facilitating Large-Conductance Ca 2+ -Activated K + Channel Remodeling in Hyperglycemia and Diabetes Mellitus

(2013) Matthew A. Nystoriak et al.   CIRCULATION RESEARCH

A Change in Configuration of the Calmodulin-KCNQ Channel Complex Underlies Ca2+-Dependent Modulation of KCNQ Channel Activity

(2013) Anastasia Kosenko et al.   PLoS One

Protein recognition and selection through conformational and mutually induced fit

(2013) Q. Wang et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

AKAP signaling complexes: pointing towards the next generation of therapeutic targets?

(2013) Jessica L. Esseltine et al.   TRENDS IN PHARMACOLOGICAL SCIENCES

Coordinated signal integration at the M-type potassium channel upon muscarinic stimulation

(2012) Anastasia Kosenko et al.   EMBO JOURNAL

Structure of a Ca2+/CaM:Kv7.4 (KCNQ4) B-Helix Complex Provides Insight into M Current Modulation

(2012) Qiang Xu et al.   JOURNAL OF MOLECULAR BIOLOGY

Inhibition of the NFAT Pathway Alleviates Amyloid Beta Neurotoxicity in a Mouse Model of Alzheimer's Disease

(2012) E. Hudry et al.   JOURNAL OF NEUROSCIENCE

Distinct Dendritic Spine and Nuclear Phases of Calcineurin Activation after Exposure to Amyloid-  Revealed by a Novel Fluorescence Resonance Energy Transfer Assay

(2012) H.-Y. Wu et al.   JOURNAL OF NEUROSCIENCE

AKAP150-Anchored Calcineurin Regulates Synaptic Plasticity by Limiting Synaptic Incorporation of Ca2+-Permeable AMPA Receptors

(2012) J. L. Sanderson et al.   JOURNAL OF NEUROSCIENCE

Dual-objective STORM reveals three-dimensional filament organization in the actin cytoskeleton

(2012) Ke Xu et al.   NATURE METHODS

Balanced interactions of calcineurin with AKAP79 regulate Ca2+–calcineurin–NFAT signaling

(2012) Huiming Li et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

Activity-Dependent Transcriptional Regulation of M-Type (Kv7) K+ Channels by AKAP79/150-Mediated NFAT Actions

(2012) Jie Zhang et al.   NEURON

Ca2+ signaling amplification by oligomerization of L-type Cav1.2 channels

(2012) R. E. Dixon et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Actin, Spectrin, and Associated Proteins Form a Periodic Cytoskeletal Structure in Axons

(2012) K. Xu et al.   SCIENCE

In Calmodulin–IQ Domain Complexes, the Ca2+-Free and Ca2+-Bound Forms of the Calmodulin C-Lobe Direct the N-Lobe to Different Binding Sites

(2011) D. J. Black et al.   BIOCHEMISTRY

Restoration of Normal L-Type Ca 2+ Channel Function During Timothy Syndrome by Ablation of an Anchoring Protein

(2011) Edward P. Cheng et al.   CIRCULATION RESEARCH

AKAP79/150 Signal Complexes in G-Protein Modulation of Neuronal Ion Channels

(2011) J. Zhang et al.   JOURNAL OF NEUROSCIENCE

AKAP Signaling Complexes in Regulation of Excitatory Synaptic Plasticity

(2011) Jennifer L. Sanderson et al.   NEUROSCIENTIST

Architecture and dynamics of an A-kinase anchoring protein 79 (AKAP79) signaling complex

(2011) M. G. Gold et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Increased Coupled Gating of L-Type Ca 2+ Channels During Hypertension and Timothy Syndrome

(2010) Manuel F. Navedo et al.   CIRCULATION RESEARCH

Ca2+/Calmodulin Disrupts AKAP79/150 Interactions with KCNQ (M-Type) K+ Channels

(2010) M. Bal et al.   JOURNAL OF NEUROSCIENCE

Superresolution Imaging of Chemical Synapses in the Brain

(2010) Adish Dani et al.   NEURON

Channelopathies linked to plasma membrane phosphoinositides

(2010) Diomedes E. Logothetis et al.   PFLUGERS ARCHIV-EUROPEAN JOURNAL OF PHYSIOLOGY

PIP2 Is a Necessary Cofactor for Ion Channel Function: How and Why?

(2008) Byung-Chang Suh et al.   Annual Review of Biophysics

Calmodulin binding to M-type K+channels assayed by TIRF/FRET in living cells

(2008) Manjot Bal et al.   JOURNAL OF PHYSIOLOGY-LONDON

Regulation of neural KCNQ channels: signalling pathways, structural motifs and functional implications

(2008) Ciria C. Hernandez et al.   JOURNAL OF PHYSIOLOGY-LONDON