Intraneuronal β-amyloid and its interactions with proteins and subcellular organelles

Hyperphosphorylated Tau is a Cause of Neuronal Dysfunction in Tauopathy

(2017) Akihiko Takashima   JOURNAL OF ALZHEIMERS DISEASE

Immunohistochemical Visualization of Amyloid-β Protein Precursor and Amyloid-β in Extra- and Intracellular Compartments in the Human Brain

(2017) Leena Aho et al.   JOURNAL OF ALZHEIMERS DISEASE

Alzheimer culprits: Cellular crossroads and interplay

(2012) Sylvie Claeysen et al.   CELLULAR SIGNALLING

The mechanism of γ-Secretase dysfunction in familial Alzheimer disease

(2012) Lucía Chávez-Gutiérrez et al.   EMBO JOURNAL

Neuronal receptors as targets for the action of amyloid-beta protein (Aβ) in the brain

(2012) Aarti N. Patel et al.   EXPERT REVIEWS IN MOLECULAR MEDICINE

Prion-like spread of protein aggregates in neurodegeneration: Figure 1.

(2012) Magdalini Polymenidou et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Spreading of Neurodegenerative Pathology via Neuron-to-Neuron Transmission of  -Amyloid

(2012) S. Nath et al.   JOURNAL OF NEUROSCIENCE

Transgenic Expression of Intraneuronal A 42 But Not A 40 Leads to Cellular A  Lesions, Degeneration, and Functional Impairment without Typical Alzheimer's Disease Pathology

(2012) D. Abramowski et al.   JOURNAL OF NEUROSCIENCE

Endoplasmic Reticulum Enrollment in Alzheimer’s Disease

(2012) Ricardo J. S. Viana et al.   MOLECULAR NEUROBIOLOGY

Prion-like behaviour and tau-dependent cytotoxicity of pyroglutamylated amyloid-β

(2012) Justin M. Nussbaum et al.   NATURE

Integrating the Alzheimer's Disease Proteome and Transcriptome: A Comprehensive Network Model of a Complex Disease

(2012) Peter Hallock et al.   OMICS-A JOURNAL OF INTEGRATIVE BIOLOGY

Trans-Synaptic Spread of Tau Pathology In Vivo

(2012) Li Liu et al.   PLoS One

Impaired neurotransmission caused by overexpression of  -synuclein in nigral dopamine neurons

(2012) M. Lundblad et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Neurotransmitter receptors and cognitive dysfunction in Alzheimer's disease and Parkinson's disease

(2012) Yunqi Xu et al.   PROGRESS IN NEUROBIOLOGY

α-Synuclein misfolding and Parkinson's disease

(2011) Leonid Breydo et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE

Targeted protein-omic methods are bridging the gap between proteomic and hypothesis-driven protein analysis approaches

(2011) Ronald J Hause et al.   Expert Review of Proteomics

Amyloid β-Mediated Cell Death of Cultured Hippocampal Neurons Reveals Extensive Tau Fragmentation without Increased Full-length Tau Phosphorylation

(2011) Jack Reifert et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Interactions of Pathological Hallmark Proteins

(2011) Judit Oláh et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Tau Protein Is Required for Amyloid  -Induced Impairment of Hippocampal Long-Term Potentiation

(2011) O. A. Shipton et al.   JOURNAL OF NEUROSCIENCE

A Quantitative Proteomic Approach to Prion Disease Biomarker Research: Delving into the Glycoproteome

(2011) Xin Wei et al.   JOURNAL OF PROTEOME RESEARCH

Protein Array Based Interactome Analysis of Amyloid-β Indicates an Inhibition of Protein Translation

(2011) Dezso P. Virok et al.   JOURNAL OF PROTEOME RESEARCH

In Situ Measurements of the Formation and Morphology of Intracellular β-Amyloid Fibrils by Super-Resolution Fluorescence Imaging

(2011) Gabriele S. Kaminski Schierle et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Post-translational modifications of tau protein: Implications for Alzheimer's disease

(2011) Ludovic Martin et al.   NEUROCHEMISTRY INTERNATIONAL

Systems biology of Alzheimer's disease: How diverse molecular changes result in memory impairment in AD

(2011) Gábor Juhász et al.   NEUROCHEMISTRY INTERNATIONAL

Diagnosis of Alzheimer's Disease Based on Disease-Specific Autoantibody Profiles in Human Sera

(2011) Eric Nagele et al.   PLoS One

The Molecular Assembly of Amyloid Aβ Controls Its Neurotoxicity and Binding to Cellular Proteins

(2011) Claudia Manzoni et al.   PLoS One

The Monomer State of Beta-Amyloid: Where the Alzheimer's Disease Protein Meets Physiology

(2011) M.L. Giuffrida et al.   REVIEWS IN THE NEUROSCIENCES

Proteostasis and Movement Disorders: Parkinson's Disease and Amyotrophic Lateral Sclerosis

(2011) D. A. Bosco et al.   Cold Spring Harbor Perspectives in Biology

Prions

(2011) D. W. Colby et al.   Cold Spring Harbor Perspectives in Biology

Intraneuronal β-amyloid accumulation and synapse pathology in Alzheimer’s disease

(2010) Gunnar K. Gouras et al.   ACTA NEUROPATHOLOGICA

The cholinergic system in aging and neuronal degeneration

(2010) Reinhard Schliebs et al.   BEHAVIOURAL BRAIN RESEARCH

Dendritic Function of Tau Mediates Amyloid-β Toxicity in Alzheimer's Disease Mouse Models

(2010) Lars M. Ittner et al.   CELL

Sorting of the Alzheimer's Disease Amyloid Precursor Protein Mediated by the AP-4 Complex

(2010) Patricia V. Burgos et al.   DEVELOPMENTAL CELL

Alzheimer Disease

(2010) Rudy J. Castellani et al.   DM DISEASE-A-MONTH

Neurotoxicity of Alzheimer's disease Aβ peptides is induced by small changes in the Aβ42 to Aβ40 ratio

(2010) Inna Kuperstein et al.   EMBO JOURNAL

Quantitative phosphoproteomic analysis of neuronal intermediate filament proteins (NF-M/H) in Alzheimer's disease by iTRAQ

(2010) Parvathi Rudrabhatla et al.   FASEB JOURNAL

Synthetic Triterpenoids Target the Arp2/3 Complex and Inhibit Branched Actin Polymerization

(2010) Ciric To et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

A guide to super-resolution fluorescence microscopy

(2010) Lothar Schermelleh et al.   JOURNAL OF CELL BIOLOGY

A Mouse Model of Amyloid   Oligomers: Their Contribution to Synaptic Alteration, Abnormal Tau Phosphorylation, Glial Activation, and Neuronal Loss In Vivo

(2010) T. Tomiyama et al.   JOURNAL OF NEUROSCIENCE

Two-dimensional gel electrophoresis in proteomics: Past, present and future

(2010) Thierry Rabilloud et al.   Journal of Proteomics

Back to the basics: Maximizing the information obtained by quantitative two dimensional gel electrophoresis analyses by an appropriate experimental design and statistical analyses

(2010) Luis Valledor et al.   Journal of Proteomics

Neuronal transport: myosins pull the ER

(2010) Michael Stiess et al.   NATURE CELL BIOLOGY

Amyloid-β and tau — a toxic pas de deux in Alzheimer's disease

(2010) Lars M. Ittner et al.   NATURE REVIEWS NEUROSCIENCE

The genetic architecture of Alzheimer's disease: beyond APP, PSENs and APOE

(2010) Rita J. Guerreiro et al.   NEUROBIOLOGY OF AGING

ADDLs and the signaling web that leads to Alzheimer’s disease

(2010) Grant A. Krafft et al.   NEUROPHARMACOLOGY

Development and Validation of a Method for Profiling Post-Translational Modification Activities Using Protein Microarrays

(2010) Sonia V. del Rincón et al.   PLoS One

Subcellular proteomics revealed the epithelial-mesenchymal transition phenotype in lung cancer

(2010) Li-Ping Li et al.   PROTEOMICS

Peripherally Applied A -Containing Inoculates Induce Cerebral  -Amyloidosis

(2010) Y. S. Eisele et al.   SCIENCE

Classification and basic pathology of Alzheimer disease

(2009) Charles Duyckaerts et al.   ACTA NEUROPATHOLOGICA

Intraneuronal pyroglutamate-Abeta 3–42 triggers neurodegeneration and lethal neurological deficits in a transgenic mouse model

(2009) Oliver Wirths et al.   ACTA NEUROPATHOLOGICA

Mechanisms of tau-induced neurodegeneration

(2009) Khalid Iqbal et al.   ACTA NEUROPATHOLOGICA

Clathrin-mediated endocytosis and Alzheimer's disease: An update

(2009) Fangbai Wu et al.   AGEING RESEARCH REVIEWS

The Unfolded Protein Response Is Activated in Pretangle Neurons in Alzheimer's Disease Hippocampus

(2009) Jeroen J.M. Hoozemans et al.   AMERICAN JOURNAL OF PATHOLOGY

Neuropathology of Lewy body disorders

(2009) Enikö Kövari et al.   BRAIN RESEARCH BULLETIN

The amyloid hypothesis for Alzheimer’s disease: a critical reappraisal

(2009) John Hardy   JOURNAL OF NEUROCHEMISTRY

An update on clinical proteomics in Alzheimer’s research

(2009) Minna A. Korolainen et al.   JOURNAL OF NEUROCHEMISTRY

Low molecular weight Aβ induces collapse of endoplasmic reticulum

(2009) Cora Sau-Wan Lai et al.   MOLECULAR AND CELLULAR NEUROSCIENCE

Alzheimer's disease

(2009) Lennart Mucke   NATURE

Amyloid-  and tau synergistically impair the oxidative phosphorylation system in triple transgenic Alzheimer's disease mice

(2009) V. Rhein et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Cytoskeletal pathologies of Alzheimer disease

(2009) James R. Bamburg et al.   CELL MOTILITY AND THE CYTOSKELETON

Clinical proteomics in neurodegenerative disorders

(2008) H. Zetterberg et al.   ACTA NEUROLOGICA SCANDINAVICA

Mass spectrometry for proteomics

(2008) Xuemei Han et al.   CURRENT OPINION IN CHEMICAL BIOLOGY

Detergent-insoluble Aggregates Associated with Amyotrophic Lateral Sclerosis in Transgenic Mice Contain Primarily Full-length, Unmodified Superoxide Dismutase-1

(2008) Bryan F. Shaw et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Flotillin-Dependent Clustering of the Amyloid Precursor Protein Regulates Its Endocytosis and Amyloidogenic Processing in Neurons

(2008) A. Schneider et al.   JOURNAL OF NEUROSCIENCE

ER stress is involved in Aβ‐induced GSK‐3β activation and tau phosphorylation

(2008) Rosa Resende et al.   JOURNAL OF NEUROSCIENCE RESEARCH

Characterization of the interaction between Aβ 1–42 and glyceraldehyde phosphodehydrogenase

(2008) Yann Verdier et al.   JOURNAL OF PEPTIDE SCIENCE

The amyloid  -peptide is imported into mitochondria via the TOM import machinery and localized to mitochondrial cristae

(2008) C. A. Hansson Petersen et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA