Article
Allergy
Viiu Blondal, Fredrik Sundbom, Xingwu Zhou, Robert Moverare, Magnus P. Borres, Marieann Hogman, Kjell Alving, Andrei Malinovschi, Christer Janson
Summary: This study aimed to examine the changes in asthma and rhinitis over time and identify factors contributing to the remission and persistence of these diseases. The results demonstrated that the persistence of rhinitis and asthma is associated with IgE sensitisation and total IgE levels. Participants with persistent allergic disease had higher levels of allergen sensitisation and type 2 inflammation markers at baseline compared to those who remained healthy.
CLINICAL AND TRANSLATIONAL ALLERGY
(2023)
Article
Pharmacology & Pharmacy
Miryoung Kim, Siin Kim, Hae Sun Suh
Summary: The study aims to estimate the incremental economic burden of prescription opioid misuse for the South Korean population. The results showed a significant association between prescription opioid misuse and increased economic burden.
FRONTIERS IN PHARMACOLOGY
(2022)
Article
Engineering, Environmental
Lisa Melymuk, Jonathan Blumenthal, Ondrej Sanka, Adriana Shu-Yin, Veena Singla, Katerina Sebkova, Kristi Pullen Fedinick, Miriam L. Diamond
Summary: The environmentally sound management (ESM) of polychlorinated biphenyls (PCBs) is a major challenge globally, with only 30% of countries on track to achieve the 2028 goal. While countries like Canada and Czechia are close to reaching the goal, the USA still faces significant inventory and reduction challenges. The failure to manage global PCB stocks after more than 30 years highlights the need to prioritize reducing production and use of other persistent organic pollutants (POPs).
ENVIRONMENTAL SCIENCE & TECHNOLOGY
(2022)
Article
Dermatology
Vida Mortezaee, Seyed Alireza Mahdaviani, Mihan Pourabdollah, Maryam Hassanzad, Maryam Sadat Mirenayat, Payam Mehrian, Naser Behnampour, Jamshid Yazdani Charati, Zahra Peirovi, Somayeh Sharifynia, Seyedmojtaba Seyedmousavi, Mohammad T. Hedayati
Summary: This study evaluated three main algorithms for diagnosing ABPA in patients with PAA, and found that algorithm C had higher specificity. Both sIgEAf and sIgGAf showed high sensitivity, and a consensus pattern combining elements of all three criteria may warrant a better diagnostic algorithm.
Article
Immunology
Shilin Wang, Hao Liu, Peiwen Yang, Zhiwen Wang, Poyi Hu, Ping Ye, Jiahong Xia, Shu Chen
Summary: This Mendelian randomization study aimed to examine the bidirectional causality between allergic diseases (AD) and cardiovascular diseases (CVD). The study found associations between asthma and atrial fibrillation, as well as between heart failure and allergic diseases. However, further investigation is needed to determine whether AD affects other CVD and to establish the causality between them.
FRONTIERS IN IMMUNOLOGY
(2023)
Article
Pharmacology & Pharmacy
Rui Zhu, Xiaoning Wang, Eric Anderson, Michelle Deng, Scott Pivirotto, Jin Jin, Nastya Kassir, Ryan Owen
Summary: Omalizumab is the first anti-IgE agent approved for the treatment of allergic asthma in adults and adolescents. This study aims to characterize the relationship between serum free IgE and pulmonary function in pediatric patients using a population-based pharmacodynamic model. The model successfully describes the IgE-FEV1 relationship in pediatrics, confirming the appropriateness of omalizumab dosing rationale. The pediatric model can be used to predict population FEV1 response when combined with an omalizumab pharmacokinetic-IgE model.
Article
Psychology, Multidisciplinary
Jeannette B. B. Peters, Jeanine C. C. Antons, Eleonore H. H. Koolen, Hanneke A. C. van Helvoort, Hieronymus W. H. van Hees, Bram van den Borst, Martijn A. A. Spruit, Jan H. H. Vercoulen, Alex J. J. van 't Hul
Summary: This study found that low levels of patient activation are common among patients with asthma and COPD. However, with a relatively simple intervention, patients can achieve higher levels of activation, enabling them to better adopt self-management techniques.
FRONTIERS IN PSYCHOLOGY
(2022)
Review
Pediatrics
Po-Yu Huang, Ying-Hsien Huang, Mindy Ming-Huey Guo, Ling-Sai Chang, Ho-Chang Kuo
Summary: This review identified a higher prevalence of allergic diseases, such as allergic rhinitis and urticaria, in children with Kawasaki disease. Intravenous immunoglobulin therapy can reduce allergic symptoms in these patients. Long-term care for Kawasaki disease patients should focus on the management of allergic diseases.
FRONTIERS IN PEDIATRICS
(2021)
Article
Multidisciplinary Sciences
Ameer Kakaje, Mohammad Marwan Alhalabi, Ayham Alyousbashi, Ayham Ghareeb
Summary: Allergic rhinitis (AR) and Laryngopharyngeal reflux (LPR) are common medical conditions that can overlap, especially in individuals with asthma. The presence of asthma is associated with higher likelihoods of developing AR and LPR, which can significantly impact quality of life. More research is needed to better understand the relationships between these conditions.
SCIENTIFIC REPORTS
(2021)
Article
Nutrition & Dietetics
Chi-Yu Yang, Fang-Yu Zhang, I-Jen Wang
Summary: This study evaluated the effects of probiotics administered via tracheal or oral routes on allergies or asthma. Results showed that the administration of Lactobacillus paracasei 33 (LP33) reduced inflammatory cell count, IgE concentration, and TH2 cell cytokine levels in the bronchoalveolar-lavage fluid. LP33 can be used to prevent allergic asthma induced by aerosol particles, but the dosage and form need to be adjusted to minimize lung tissue irritation.
Article
Immunology
Meiping Chen, Shiyi He, Phoebe Miles, Chunlin Li, Yijun Ge, Xuechan Yu, Linfeng Wang, Weina Huang, Xue Kong, Shanni Ma, Yiting Li, Qingwen Jiang, Wen Zhang, Chao Cao
Summary: Perturbation of the nasal microbiome is associated with the phenotypes and severity of chronic airways disease, including asthma and allergic rhinitis.
FRONTIERS IN CELLULAR AND INFECTION MICROBIOLOGY
(2022)
Article
Computer Science, Interdisciplinary Applications
M. T. Ghozali, Satibi Satibi, Zullies Ikawati, Lutfan Lazuardi
Summary: The development of the Google Android OS asthma self-management smartphone app AsmaDroid was successfully completed using the Patient-Centered Design approach, with functions including asthma education, list of asthma medications, asthma diary, peak flow record, etc. The app showed a very high average success rate, indicating its effectiveness.
COMPUTER METHODS AND PROGRAMS IN BIOMEDICINE
(2021)
Article
Public, Environmental & Occupational Health
Terri L. Byczkowski, Anna-Liisa B. Vockell, David J. Krier, Maria T. Britto
Summary: This study aimed to develop a questionnaire to segment adolescents with asthma into different archetypes based on their motivations for individualized self-management interventions. Six archetypes were identified and described, and a 17-item questionnaire was developed to identify these archetypes. The study has important implications for healthcare professionals to customize adherence interventions for different segments of adolescents.
PATIENT EDUCATION AND COUNSELING
(2022)
Review
Medicine, General & Internal
Bernardo Sousa-Pinto, Rafael Jose Vieira, Jan Brozek, Antonio Cardoso-Fernandes, Nuno Lourenco-Silva, Renato Ferreira-da-Silva, Andre Ferreira, Sara Gil-Mata, Anna Bedbrook, Ludger Klimek, Joao A. Fonseca, Torsten Zuberbier, Holger J. Schunemann, Jean Bousquet
Summary: This systematic review aims to analyze the effectiveness differences among different intranasal specific medications in the treatment of allergic rhinitis. The study will assess the impact of intranasal antihistamines and corticosteroids on nasal and ocular symptoms as well as quality of life in patients with rhinitis.
Article
Cardiac & Cardiovascular Systems
Zuzana Diamant, Maurits van Maaren, Antonella Muraro, Milos Jesenak, Ilja Striz
Summary: Allergen specific immunotherapy (AIT) is the only causal therapeutic option for allergic airway diseases. Recent real life data on long-term effectiveness of AIT further underscored its unique therapeutic potential. More widespread use of this treatment should further move this promising therapeutic field.
RESPIRATORY MEDICINE
(2023)
