Article
Chemistry, Analytical
Mariam Saleem, Hamid Latif, Dalaver H. Anjum, Syeda Ammar Shabbir, Abdul Sattar, Arslan Usman
Summary: An easy, quick, and efficient detection of Multidrug Resistance (MDR) of cancer cells at the clinical level is crucial for effective treatment of leukemia patients. A carbon nanomaterials-based biosensor utilizing Au nanoparticles (Au-NPs) decorated on Nitrogen-doped Graphene (NG) and Single-Walled Carbon Nanotubes (SWCNTs) has been developed for sensitive and efficient detection of affected DNA. This study provides insights for the development of new portable biosensors for MDR gene detection, enabling early diagnosis of cancer at the clinical level.
MICROCHEMICAL JOURNAL
(2023)
Article
Chemistry, Analytical
Yu-Syuan Lin, Li-Wei Chuang, Bo-Yi Wu, Yi-Hui Lin, Huan-Tsung Chang
Summary: A GSH-assisted approach using a polymer template was used to prepare stable and fluorescent gold nanoclusters. The polymer PDDA was found to be more suitable for the preparation of Au NCs compared to PSS. These nanoclusters demonstrated high sensitivity and selectivity for sulfide ions.
SENSORS AND ACTUATORS B-CHEMICAL
(2021)
Article
Biochemical Research Methods
Sila Can Osmanogullari, Mehrdad Forough, Ozgul Persil Cetinkol, Yasemin Arslan Udum, Levent Toppare
Summary: This study successfully fabricated a graphite electrode biosensor modified with gold nanoparticles (AuNPs) to investigate the interactions between OXP and the G4-forming promoter region (Pu22) of VEGF. DPV was used to monitor the decrease in guanine oxidation signal and investigate the interactions between OXP and Pu22-G4 DNA. Our findings provide new insights into the interactions between VEGF G4 and OXP.
ANALYTICAL BIOCHEMISTRY
(2023)
Article
Chemistry, Analytical
Wenli Jiang, Die Sun, Chenxin Cai, Hui Zhang
Summary: In this study, a plasmon-enhanced electrochemical sensor has been developed for the detection of extracellular hydrogen peroxide (H2O2) from cancer cells. Pd-tipped Au nanobipyramids (PTA NBPs) were used as the electrocatalysts. The sensor showed high sensitivity, low detection limit, wide linear range, good stability, and repeatability. It also enabled the measurement of extracellular H2O2 derived from cancer cells.
Article
Chemistry, Multidisciplinary
Kirti Saxena, Arun Kumar, Nidhi Chauhan, Manika Khanuja, Bansi D. Malhotra, Utkarsh Jain
Summary: An electrochemical biosensor was designed for detecting a specific toxin of Helicobacter pylori, utilizing a nanocomposite-modified gold electrode and VacA antibodies for detection. The sensor showed good stability, sensitivity, and selectivity.
Article
Chemistry, Analytical
Dilek Eskikoy Bayraktepe, Ceren Yildiz, Zehra Yazan
Summary: We present a new and facile method for fabricating an electrochemical DNA biosensor using a DNA/AuPt/p-L-Met coating on a screen-printed carbon electrode (SPE) and demonstrate its application in the detection of cancer therapy agents, Imatinib and Erlotinib. Poly-L-methionine (p-L-Met), gold, and platinum nanoparticles (AuPt) were electrodeposited onto the SPE in one step using a solution containing L-Met, HAuCl4, and H2PtCl6. DNA immobilization was achieved through drop-casting on the modified electrode surface. Various characterization techniques were employed to investigate the sensor's morphology, structure, and electrochemical performance. The optimized biosensor exhibited excellent sensitivity and selectivity for quantifying Imatinib and Erlotinib in human serum and pharmaceutical samples, with low LODs of 0.18 nM and 0.009 nM, respectively.
Article
Chemistry, Multidisciplinary
Chen Chen, Jin-Xin Ma, Hui Wang, Hui-Qiao Liu, Shu-Wei Ren, Jun-Tao Cao, Yan-Ming Liu
Summary: A spatially resolved ratiometric electrochemiluminescence immunosensor was developed for myoglobin detection, using resonance energy transfer for signal amplification. The sensor exhibited high selectivity, sensitivity, and accuracy, making it a promising tool for biomarker analysis.
NEW JOURNAL OF CHEMISTRY
(2022)
Article
Nanoscience & Nanotechnology
Senyao Wang, Baoshan He, Wenjie Ren, Zhiguang Suo, Yiwei Xu, Min Wei, Huali Jin
Summary: In this study, a novel electrochemical aptasensor was developed for sensitive and accurate determination of chloramphenicol (CAP) residues in animal-derived products. The aptasensor incorporated a poly-(diallyldimethylammonium chloride) functionalized graphene/Ag@Au nanosheets composite modified electrode and a DNAzyme signal amplification effect triggered by a triple-helix molecular switch (THMS). The aptasensor showed high sensitivity and specificity for CAP, and was not affected by interference from other antibiotics and common metal ions. The method also performed well when applied to measuring CAP in milk powder.
ACS APPLIED MATERIALS & INTERFACES
(2022)
Article
Agriculture, Dairy & Animal Science
Yuanyuan Hui, Haishuai Peng, Fuxin Zhang, Lei Zhang, Liu Yufang, Aiqing Zhao, Rong Jia, Bini Wang, Yuxuan Song
Summary: This study developed a novel electrochemical aptasensor for sensitive and specific detection of AFM(1) in dairy products. The method showed a wide detection range and low detection limit, and it performed well in the detection of AFM(1) in cow, goat, and sheep milk samples.
JOURNAL OF DAIRY SCIENCE
(2022)
Article
Chemistry, Analytical
Shuzhou Guo, Yaping Lin, Ziqi Lian, Tao Zeng, Liangliang Wang, Rongkai Ye, Benlin Hong, Qianwei Liang, Qianqing Wu, Jianqiang Hu, Aiqing Li
Summary: In this study, a label-free ultrasensitive biosensor was successfully developed for instant detection of miRNA-21, which has wide applications in early diagnosis of diseases like cancer and acute kidney injury. The biosensor showed high sensitivity, wide linear range, low limit of detection, and demonstrated specificity, stability, and reproducibility in detecting miRNA-21 in real urine samples.
MICROCHEMICAL JOURNAL
(2023)
Article
Chemistry, Analytical
Zhixue Yu, Hui Wang, Yiguang Zhao, Fan Zhang, Xiangfang Tang, Benhai Xiong
Summary: An electrochemical biosensor was developed for detecting Ca2+ concentration through electrode modification and signal amplification. The biosensor showed promising results in determining the concentration of Ca2+ in dairy cow serum.
Article
Chemistry, Multidisciplinary
Dimpo S. Sipuka, Foluke O. G. Olorundare, Sesethu Makaluza, Nyasha Midzi, Tsholofelo I. Sebokolodi, Omotayo A. Arotiba, Duduzile Nkosi
Summary: Dopamine, an important neurotransmitter and biomarker, plays a vital role in our neurological system and body, making it essential to monitor its concentration levels. Researchers developed an aptamer-based sensor using an electro-co-deposition technique to immobilize a single-stranded thiolated dopamine aptamer on a modified electrode. The sensor exhibited selective detection of dopamine from 10-200 nM, with a limit of detection of 0.26 nM and 0.011 nM using square wave voltammetry and electrochemical impedance spectroscopy, respectively. The aptasensor showed promise for detecting dopamine in complex matrices such as human serum.
Article
Biochemistry & Molecular Biology
Li Li, Zhengbo Chen
Summary: In this study, a high specificity, flexibility, and simplicity aptasensor strategy was designed using a triblock DNA probe. It was found that the polyA fragment could assemble on the gold electrode surface via polyA instead of traditional Au-S bonds, leading to improved hybridization stability. The electrochemical aptasensor showed good repeatability, stability, and specificity.
BIOELECTROCHEMISTRY
(2023)
Article
Biotechnology & Applied Microbiology
Fernanda Raquel Wust Schmitz, Karina Cesca, Alexsandra Valerio, Debora de Oliveira, Dachamir Hotza
Summary: Novel rapid methodologies involving colorimetric biosensors and gold nanoparticles have been developed for the detection of bacteria, specifically Pseudomonas aeruginosa. The biosensor relies on the color change of gold nanoparticles induced by NaCl after incubation with bacteria and aptamer binding. The optimized conditions for detection were found to be 5 μM aptamer concentration and 200 mM of NaCl. The detection limit for P. aeruginosa was 10(5) CFU mL(-1) by the naked eye and 10(4) CFU mL(-1) by UV-Vis spectrometry.
APPLIED MICROBIOLOGY AND BIOTECHNOLOGY
(2023)
Article
Chemistry, Analytical
Ying Ying, Min Zhou, Si Dai, Ming Ma, Wenfang Deng, Yueming Tan, Qingji Xie
Summary: In this work, a novel photoactive material consisting of SnO2 nanoparticles-decorated ZnIn2S4 nanosheets was developed for the photoelectrochemical/electrochemical dual-signal detection of RNase A. The modification of Au nanoparticles on the material not only facilitated the immobilization of DNA probes but also enhanced the photocurrent exciton-plasmon coupling effect. This approach enabled efficient and reliable detection of RNase A in a dual mode.
SENSORS AND ACTUATORS B-CHEMICAL
(2022)
Article
Electrochemistry
Abdul Qayoom Mugheri, Shaista Khan, Ali Asghar Sangah, Aijaz Ahmed Bhutto, Muhammad Younis Laghari, Nadeem Ahmed Mugheri, Asif Ali Jamali, Arsalan Ahmed Mugheri, Nagji Sodho, Abdul Waheed Mastoi, Aftab Kandhro
Summary: Green hydrogen has the potential to transition to a pollution-free energy infrastructure. This study proposes a solution to produce hydrogen during the photoelectrochemical process, offering greater stability and control over chemical reactions. Techno-economic assessments show the efficiency and economic feasibility of co-producing value-added chemicals to enhance green hydrogen production.
ELECTROCHIMICA ACTA
(2024)
Article
Electrochemistry
Danpeng Cheng, Wuxin Sha, Qigao Han, Shun Tang, Jun Zhong, Jinqiao Du, Jie Tian, Yuan-Cheng Cao
Summary: LiNixCoyMn1-x-yO2 (NCM) is a critical cathode material for lithium-ion batteries in electric vehicles. The aging of cathode/electrolyte interfaces leads to capacity degradation and long-term cycle instability. A novel neural network model called ACGNet is developed to predict electrochemical stability windows of crystals, allowing for high-throughput screening of coating materials. LiPO3 is identified as a promising coating material with high oxidation voltage and low cost, which significantly improves the cycle stability of NCM batteries. This study demonstrates the accuracy and potential of machine learning in battery materials.
ELECTROCHIMICA ACTA
(2024)
Article
Electrochemistry
P. Mohana, R. Yuvakkumar, G. Ravi, S. Arunmetha
Summary: This study successfully fabricates a non-noble CuO/NiO/rGO nanocomposite and investigates its electrocatalytic performance for oxygen evolution reaction in alkaline environment. The experimental results demonstrate that the electrocatalyst exhibits high activity and good stability, offering a new synthetic approach for sustainable energy production.
ELECTROCHIMICA ACTA
(2024)
Article
Electrochemistry
Qiong Qu, Jing Guo, Hongyu Wang, Kai Zhang, Jingde Li
Summary: In this study, a bifunctional electrode host design consisting of carbon nanofibers implanted ordered porous Co-decorated Al2O3 supported on carbon nanotube film (CNTF) was proposed to address the shuttling effect of lithium polysulfides (LiPSs) and dendrite formation of metal lithium anode in lithium-sulfur (Li-S) batteries. The electrode exhibited excellent conductivity, efficient confinement of LiPSs, and catalytic conversion performance, resulting in high initial capacity and good capacity retention during cycling. As an anode, the electrode showed excellent Li+ diffusion performance and uniform lithium growth behavior, achieving a dendrite-free lithium electrode. The flexible pack cell assembled from these electrodes delivered a specific capacity of 972 mAh g(-1) with good capacity retention.
ELECTROCHIMICA ACTA
(2024)
Article
Electrochemistry
Hong Zhang, Jin-Peng Yu, Chen Chen, Cheng-Yong Shu, Guang-Yu Xu, Jie Ren, Kai Cui, Wen-Fang Cai, Yun-Hai Wang, Kun Guo
Summary: Spray coating of acetylene black nanoparticles onto stainless steel mesh can enhance its biofilm formation ability and current density, making it a promising electrode material for microbial electrochemical systems. The spray coating method is simple, cost-effective, and suitable for large-size stainless steel electrodes.
ELECTROCHIMICA ACTA
(2024)
Article
Electrochemistry
Binpeng Hou, Jingjin Chen, Li-Hong Zhang, Xiaowen Shi, Zizhong Zhu
Summary: The electrochemical performance of Li1.20Mn0.44Ni0.32Co0.04O2 and its oxygen-deficient phase Li1.20Mn0.44Ni0.32Co0.04O1.83 was studied through first-principles calculations. The results show that the oxygen-deficient phase has a higher theoretical capacity but lower voltage platform and higher chemical activity compared to the pristine phase.
ELECTROCHIMICA ACTA
(2024)
Article
Electrochemistry
Yating Du, Sayoko Shironita, Daisuke Asakura, Eiji Hosono, Yoshitsugu Sone, Yugo Miseki, Eiichi Kobayashi, Minoru Umeda
Summary: This study investigates the effect of high- and low-temperature environments on the charge-discharge performance of a Li-ion battery. The deterioration mechanisms of the battery at different temperatures are analyzed through various characterization techniques. The results indicate that the battery performance deteriorates more significantly at a low-temperature environment of 5 degrees C compared to higher temperatures. The understanding of the deterioration mechanisms can contribute to the development of safer battery usage methods.
ELECTROCHIMICA ACTA
(2024)
Article
Electrochemistry
Si-Si Shi, Zhi-Xiang Yuan, Fei Zhang, Ping Chen
Summary: In this study, a new nano-electrocatalyst was prepared, which exhibited superior electrocatalytic activity for the reduction of NO2- to ammonia in a neutral electrolyte, potentially due to the synergistic enhancement between Co3O4-x and Co.
ELECTROCHIMICA ACTA
(2024)
Article
Electrochemistry
Berna Dalkiran, Havva Bekirog
Summary: This study reports the use of deep eutectic solvents (DES) based on ethylene glycol and urea as low-cost and green electrolytes for enhancing electrochemical detection of natural antioxidants. The study successfully developed a disposable and effective electrochemical sensing platform for simultaneous determination of ascorbic acid (AA) and gallic acid (GA) using NaOH nanorods on a pencil graphite electrode. The proposed electrode showed improved analytical performance, with higher peak currents and shifted oxidation potentials in DES compared to BR buffer medium.
ELECTROCHIMICA ACTA
(2024)
Article
Electrochemistry
Sijun Ren, Jianguo Huang
Summary: In this study, a novel bio-inspired nanofibrous WO3/carbon composite was synthesized using a facile hydrothermal method. The three-dimensional network structure of the composite alleviated the volume expansion of WO3 nanorods and enhanced the charge-transport kinetics. The optimized composite exhibited superior lithium storage properties.
ELECTROCHIMICA ACTA
(2024)
Article
Electrochemistry
Zhilong Zheng, Yu Chen, Hongxia Yin, Hengbo Xiao, Xiangji Zhou, Zhiwen Li, Ximin Li, Jin Chen, Songliu Yuan, Junjie Guo, Haibin Yu, Zhen Zhang, Lihua Qian
Summary: This study found that interstitial Zn cations in CoMoO4 can modulate the dissolution kinetics of Mo cations and improve the OER performance. The interstitial Zn cations can prevent the dissolution of Co cations at high potential, enhancing the durability of the catalyst.
ELECTROCHIMICA ACTA
(2024)
Article
Electrochemistry
Xiaobo Lin, Shern R. Tee, Debra J. Searles, Peter T. Cummings
Summary: Molecular dynamics simulations using the constant potential method were used to investigate the charging dynamics and charge storage of supercapacitors. The simulations revealed that the water-in-salt electrolyte exhibited the highest charge storage and significantly higher capacitance on the negative electrode. The varying contributions of different electrode regions to supercapacitor performance were also demonstrated.
ELECTROCHIMICA ACTA
(2024)
Article
Electrochemistry
Wiktoria Lipinska, Vita Saska, Katarzyna Siuzdak, Jakub Karczewski, Karol Zaleski, Emerson Coy, Anne de Poulpiquet, Ievgen Mazurenko, Elisabeth Lojou
Summary: The spatial distribution of enzymes on electrodes is important for bioelectrocatalysis. In this study, controlled spatial distribution of gold nanoparticles on Ti nanodimples was achieved. The efficiency of enzymatic O2 reduction was found to be influenced by the size of the gold nanoparticles and their colocalization with TiO2. The highest stability of enzymatic current was observed with the largest gold nanoparticles.
ELECTROCHIMICA ACTA
(2024)
Article
Electrochemistry
Tariq M. Al-Hejri, Zeenat A. Shaikh, Ahmed H. Al-Naggar, Siddheshwar D. Raut, Tabassum Siddiqui, Hamdan M. Danamah, Vijaykumar V. Jadhav, Abdullah M. Al-Enizi, Rajaram S. Mane
Summary: This study explores a promising self-growth approach for the synthesis of nickel hydroxide (Ni(OH)2) nanosponge-balls on the surface of a nickel-foam (NiF) electrode. The modified NiF electrode, named Ni(OH)2@NiF, shows distinctive nanosponge-ball morphology and demonstrates excellent energy storage capability and electrocatalytic performance in both hydrogen and oxygen evolution reactions.
ELECTROCHIMICA ACTA
(2024)
Article
Electrochemistry
Rafael Del Olmo, Gregorio Guzman-Gonzalez, Oihane Sanz, Maria Forsyth, Nerea Casado
Summary: The use of Lithium-Ion Batteries (LIBs) is becoming increasingly extensive, and it is important to optimize the devices to achieve their maximum practical specific capacity. In this study, mixed ionic-electronic conducting (MIEC) binders based on PEDOT:PSS and PEDOT: PDADMA-TFSI were developed for Li-ion cathodes, and their performance was compared with conventional formulations. The influence of electrode formulations, including the addition of conducting carbon and an Organic Ionic Plastic Cristal (OIPC), was also analyzed. The proposed binders showed improved performance compared to conventional formulations with different electrolyte types and active materials.
ELECTROCHIMICA ACTA
(2024)