Journal
ELECTROCHEMISTRY COMMUNICATIONS
Volume 16, Issue 1, Pages 44-48Publisher
ELSEVIER SCIENCE INC
DOI: 10.1016/j.elecom.2012.01.009
Keywords
TiO2 nanotube; CdS nanocrystals; Electrochemiluminescence; Immunosensor; Antigen detection
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Funding
- University of China [NECT-10-0305]
- National Natural Science Foundation of China [21005012, 11004025, 11174046]
- Fundamental Research Funds for the Central Universities [N090105001, N100405004]
- Key Laboratory of Analytical Chemistry for Life Science, Ministry of Education [KLACLS01006]
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CdS nanocrystals (NCs) are decorated homogeneously on the TiO2 nanotube arrays (TiNT) by chemical bath deposition method. The resultant CdS/TiNT composite shows largely amplified electrochemiluminescence (ECL) signals due to the vertically aligned nanotubular structure. The ultrasensitive antigen detection is achieved on the composites via an efficient ECL quenching process introduced by sandwiched immunoreaction, and shows a detection limit of 1.0 fg mL(-1). (C) 2012 Elsevier B.V. All rights reserved.
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