Electrochemical oxidaton of N,N-dialkyl-p-phenylenediamines in the presence of arylsulfinic acids. An efficient method for the synthesis of new sulfonamide derivatives

Electrochemical oxidation of N,N-dialkyl-p-phenylenediamines have been studied in the presence of arylsulfinic acids as nucleophiles in aqueous solutions. The results indicate that the electrochemically generated quinone-imines participate in Michael type addition reaction with arylsulfinic acids and via an EC mechanism convert to the corresponding new sulfonamide derivatives. In this work, an efficient and one-pot electrochemical method for the synthesis of new sulfonamide derivatives in aqueous solution is reported. (C) 2008 Elsevier BY. All rights reserved.