4.5 Article

Adsorption and Electrooxidation of Nucleic Acids at Glassy Carbon Electrodes Modified with Multiwalled Carbon Nanotubes Dispersed In Polylysine

Journal

ELECTROANALYSIS
Volume 25, Issue 5, Pages 1116-1121

Publisher

WILEY-V C H VERLAG GMBH
DOI: 10.1002/elan.201200622

Keywords

Carbon nanotubes; Genosensors; Hybridization electrochemical biosensors; DNA adsorption; Polylysine; Carbon nanotubes dispersion

Funding

  1. CONICET
  2. SECyT-UNC
  3. ANPCyT
  4. Ministerio de Ciencia e Innovacin (Spain) [CTQ2009-09791]
  5. Universidad Nacional de Cordoba (Cordoba, Argentina)
  6. Universidad Autonoma de Madrid (Madrid, Spain)

Ask authors/readers for more resources

We report the advantages of the adsorption and electrooxidation of oligonucleotides and calf-thymus double stranded DNA (dsDNA) at glassy carbon electrodes (GCE) modified with a dispersion of multiwalled carbon nanotubes (MWCNT) in poly-L-lysine (Plys) (GCE/MWCNT-Plys). Important enhancement in the guanine oxidation signal was obtained by adsorptive stripping voltammetry (AdSV) due to a most favorable interaction between the negatively charged DNAs and the positively charged Plys that support the MWCNT. The layer of oligo(dG)11 immobilized at GCE/MWCNT-Plys was successfully used for the selective detection of the hybridization event using oligo(dG)11/oligo(dC)11 as model.

Authors

I am an author on this paper
Click your name to claim this paper and add it to your profile.

Reviews

Primary Rating

4.5
Not enough ratings

Secondary Ratings

Novelty
-
Significance
-
Scientific rigor
-
Rate this paper

Recommended

Article Chemistry, Analytical

Reduced graphene oxide-carboxymethylcellulose layered with platinum nanoparticles/PAMAM dendrimer/magnetic nanoparticles hybrids. Application to the preparation of enzyme electrochemical biosensors

Boryana Borisova, Alfredo Sanchez, Sandra Jimenez-Falcao, Miriam Martin, Pedro Salazar, Concepcion Parrado, Jose M. Pingarron, Reynaldo Villalonga

SENSORS AND ACTUATORS B-CHEMICAL (2016)

Article Chemistry, Analytical

Quantification of neurotransmitters and metabolically related compounds at glassy carbon electrodes modified with bamboo-like carbon nanotubes dispersed in double stranded DNA

Alejandro Gutierrez, Emiliano N. Primo, Marcos Eguilaz, Concepcion Parrado, Maria D. Rubianes, Gustavo A. Rivas

MICROCHEMICAL JOURNAL (2017)

Article Chemistry, Analytical

Characterization of White Wines by Electrochemical Indexes Obtained Using Carbon Nanotube-modified Electrodes

Alberto Sanchez Arribas, Monica Moreno, Gabriel A. Moreno, Esperanza Bermejo, Antonio Zapardiel, Manuel Chicharro

ELECTROANALYSIS (2018)

Article Chemistry, Analytical

A comparative study of carbon nanotube dispersions assisted by cationic reagents as electrode modifiers: Preparation, characterization and electrochemical performance for gallic acid detection

Alberto Sanchez Arribas, Monica Moreno, Laura Gonzalez, Noelia Blazquez, Esperanza Bermejo, Antonio Zapardiel, Manuel Chicharro

JOURNAL OF ELECTROANALYTICAL CHEMISTRY (2020)

Article Chemistry, Analytical

Flow injection analysis with amperometric detection of polyphenols at carbon nanotube/polyvinylpyrrolidone-modified electrodes as classification tool for white wine varieties

Monica Moreno, Alberto Sanchez Arribas, Laura Gonzalez, Esperanza Bermejo, Antonio Zapardiel, Manuel Chicharro

Summary: This study presents a simple electroanalytical methodology for classification of wine samples based on their grape variety using flow injection analysis with electrochemical detection and chemometric analysis. The modified GCE electrode with CNT film showed excellent electrochemical performance for amperometric detection of polyphenols, allowing high sample throughput analysis of white wines. The developed discriminant analysis model using amperometric signals successfully assigned the grape varietal of the analyzed samples with a high mean classification rate of 97.0% in validation assays.

MICROCHEMICAL JOURNAL (2021)

Review Materials Science, Multidisciplinary

Carbon nanotubes as analytical tools in capillary electromigration methods

Monica Moreno, Alberto Sanchez Arribas, Esperanza Bermejo, Antonio Zapardiel, Manuel Chicharro

APPLIED MATERIALS TODAY (2017)

Article Biophysics

Decoration of reduced graphene oxide with rhodium nanoparticles for the design of a sensitive electrochemical enzyme biosensor for 17β-estradiol

Eloy Povedano, Fernando H. Cincotto, Concepcion Parrado, Paula Diez, Alfredo Sanchez, Thiago C. Canevari, Sergio A. S. Machado, Jose M. Pingarron, Reynaldo Villalonga

BIOSENSORS & BIOELECTRONICS (2017)

No Data Available