Article
Surgery
Pengcheng Yu, Can Hu, Yi Wang, Zhehan Bao, Ruolan Zhang, Mengxuan Cao, Yanqiang Zhang, Xiangdong Cheng, Zhiyuan Xu
Summary: This study retrospectively analyzed the clinical data of 86 gastric cancer patients, showing that preoperative chemotherapy combined with PAND can improve survival and reduce recurrence rates for patients with para-aortic lymph node metastasis.
Article
Multidisciplinary Sciences
Sung Eun Oh, Jeong Eun Seo, Ji Yeong An, Min-Gew Choi, Tae Sung Sohn, Jae Moon Bae, Sung Kim, Jun Ho Lee
Summary: This study aimed to validate the safety and feasibility of reduced-port laparoscopic surgery with complete D2 lymph node dissection for gastric cancer. The results showed that Duet TLDG is a safe surgical method oncologically and technically, but the compliance rate needs to be further improved, with a postoperative complication rate of 20.0%.
SCIENTIFIC REPORTS
(2021)
Article
Surgery
Sejin Lee, Jeong Ho Song, Seohee Choi, Minah Cho, Yoo Min Kim, Hyoung-Il Kim, Woo Jin Hyung
Summary: Fluorescent lymphography is effective in complete lymph node dissection at the splenic hilum during minimally invasive total gastrectomy, improving the number of retrieved lymph nodes and reducing the risk of metastasis. It may also help to increase relapse-free survival in patients without lymph node metastasis.
SURGICAL ENDOSCOPY AND OTHER INTERVENTIONAL TECHNIQUES
(2022)
Article
Oncology
Fiona Speichinger, Mihnea P. Dragomir, Simon Schallenberg, Florian N. Loch, Claudius E. Degro, Ann-Kathrin Baukloh, Lisa Hartmann, Ioannis Pozios, Christian Schineis, Georgios Antonios Margonis, Johannes C. Lauscher, Katharina Beyer, Carsten Kamphues
Summary: The lymph node invasion mechanism plays a prognostic role in pancreatic ductal adenocarcinoma (PDAC) after resection, but it is not addressed in the current cancer classification system. This study analyzed the prognostic role of different mechanisms of lymph node invasion on PDAC and suggests a rethinking of the TNM classification based on lymph node metastasis mechanisms in PDAC.
Article
Oncology
Xinghua Cheng, Wanqin Zeng, Yuan Liu, Zuodong Song, Yuchen Han, Qingquan Luo, Shun Lu
Summary: This study investigated the impact of LN dissection on patient survival and tumor recurrence in cT1-2N0M0 SCLC. The results showed that the dissection group had better overall survival and recurrence-free survival, as well as a lower rate of local recurrence compared to the sampling group. LN dissection retained its independent favorable effects even after adjustment. The overall nodal upstaging rate was 37.6%, and the dissection group had a tendency of better recurrence-free survival in both pN0 and pN+ patients.
ANNALS OF SURGICAL ONCOLOGY
(2022)
Article
Oncology
Xinxin Cheng, Yaxin Lu, Sai Chen, Weilin Yang, Bo Xu, Jianyong Zou, Zhenguang Chen
Summary: This study developed a nomogram to predict lymph node metastasis in thymic epithelial tumors and constructed the LNMRS model for predicting lymphatic involvement, which was more convenient than the nomogram. The models showed excellent predictive performance for lymph node metastasis.
ANNALS OF SURGICAL ONCOLOGY
(2022)
Article
Oncology
Cristina Diaz del Arco, Lourdes Estrada Munoz, Andres Sanchez Pernaute, Luis Ortega Medina, Soledad Garcia Gomez de las Heras, Ricardo Garcia Martinez, Maria Jesus Fernandez Acenero
Summary: This study compared the prognostic value of 3 different LN classifications for patients with resected GC, showing that LNR-based classification stratified patients better for prognosis assessment. Further studies are needed to evaluate the impact of the number of LN examined, cutoff values, and anatomic extent of LN disease in GC.
AMERICAN JOURNAL OF CLINICAL ONCOLOGY-CANCER CLINICAL TRIALS
(2021)
Article
Oncology
Wenjie Lv, Dawen Zheng, Wenbin Guan, Ping Wu
Summary: Trichilemmal carcinoma, despite being considered a tumor of low malignant potential, still carries the risk of recurrence and metastasis. Regional lymph node dissection followed by local radiotherapy is recommended for patients with lymph node metastases. Screening for metastasis and close follow-up are essential for improving prognosis.
FRONTIERS IN ONCOLOGY
(2022)
Article
Surgery
Andrea Romanzi, Raffaello Mancini, Luigi Ioni, Tullio Picconi, Graziano Pernazza
Summary: ICG-guided fluorescent lymphography can assist in performing a more accurate locoregional lymphadenectomy during robotic subtotal gastrectomy for gastric cancer, leading to a higher number of LNs retrieved without complications. This technique represents a significant contribution to gastric cancer surgery.
INTERNATIONAL JOURNAL OF MEDICAL ROBOTICS AND COMPUTER ASSISTED SURGERY
(2021)
Article
Surgery
Makoto Hikage, Keiichi Fujiya, Satoshi Kamiya, Yutaka Tanizawa, Etsuro Bando, Akifumi Notsu, Masanori Terashima
Summary: This study evaluated the long-term outcomes and prognostic factors of gastrectomy with D2 and paraaortic lymph node dissection (PAND) for patients with locally advanced gastric cancer. The results showed that neoadjuvant chemotherapy and the number of metastatic paraaortic lymph nodes on preoperative imaging were independently associated with relapse-free survival.
LANGENBECKS ARCHIVES OF SURGERY
(2022)
Article
Surgery
Keiji Hayata, Toshiyasu Ojima, Masaki Nakamura, Junya Kitadani, Akihiro Takeuchi, Hiroki Yamaue
Summary: The CAVING approach allows for safe and effective PAN lymph node dissection during laparoscopic surgery, minimizing interference with the pancreas and spleen.
LANGENBECKS ARCHIVES OF SURGERY
(2021)
Article
Medicine, General & Internal
Harbi Khalayleh, Young-Woo Kim, Hong Man Yoon, Keun Won Ryu, Myeong-Cherl Kook
Summary: Proximal gastrectomy (PG) may be safely performed for cT1-T2N0/1M0 tumors less than 4.1 cm in diameter located in the upper third of the stomach. cT3N0/1M0-differentiated tumors less than 4.1 cm may also be eligible for PG, while poorly differentiated cT3 tumors and any cT4 or cN2/3 diseases require total gastrectomy.
Article
Oncology
Andrew J. Sinnamon, Michelle Savoldy, Rutika Mehta, Sean P. Dineen, Luis R. Pena, Gregory Y. Lauwers, Jose M. Pimiento
Summary: This study aimed to examine the prognostic value of the current NCCN definition of TRG in LRGC. The results showed that TRG0 is rare but has a good prognosis, while the pathologic lymph node status is the strongest prognostic factor.
ANNALS OF SURGICAL ONCOLOGY
(2023)
Article
Oncology
Xiu-Mei Deng, Tian-Yu Zhu, Guo-Jun Wang, Bu-Lang Gao, Jing-Tao Wang, Rui-Xin Li, Yun-Fei Zhang, Heng-Xuan Ding
Summary: The study showed that dissection of the left gastric artery lymph nodes is crucial in preventing residual or metastasis of esophageal squamous carcinomas, based on the lymphatic drainage pathway revealed by carbon nanoparticle labeling. Specific patterns in lymph node metastasis of esophageal cancer were identified, emphasizing the importance of thorough lymph node dissection in radical esophagectomy.
WORLD JOURNAL OF SURGICAL ONCOLOGY
(2021)
Article
Oncology
Siamak Daneshmand, Clint Cary, Timothy Masterson, Lawrence Einhorn, Nabil Adra, Stephen A. Boorjian, Christian Kollmannsberger, Anne Schuckman, Alan So, Peter Black, Aditya Bagrodia, Eila Skinner, Mehrdad Alemozaffar, Timothy Brand, Scott Eggener, Phillip Pierorazio, Kelly Stratton, Lucia Nappi, Craig Nichols, Chunqiao Luo, Ming Li, Brian Hu
Summary: This study aimed to investigate the efficacy of RPLND as a first-line treatment for testicular seminoma with clinically low-volume retroperitoneal lymphadenopathy. The results showed that the 2-year recurrence-free survival rate was 81%, the recurrence rate was 22%, and the 2-year overall survival rate was 100%. The study concluded that RPLND is a viable treatment option with low long-term morbidity.
JOURNAL OF CLINICAL ONCOLOGY
(2023)
Article
Oncology
Blake D. Babcock, Mayada A. Aljehani, Brice Jabo, Audrey H. Choi, John W. Morgan, Matthew J. Selleck, Fabrizio Luca, Elizabeth Raskin, Mark E. Reeves, Carlos A. Garberoglio, Sharon S. Lum, Maheswari Senthil
ANNALS OF SURGICAL ONCOLOGY
(2018)
Article
Oncology
Edoardo Botteri, Andriy Krendyukov, Giuseppe Curigliano
EUROPEAN JOURNAL OF CANCER
(2018)
Article
Medicine, General & Internal
E. Botteri, T. de Lange, S. Tonstad, P. Berstad
JOURNAL OF INTERNAL MEDICINE
(2018)
Article
Oncology
Carlo Corbellini, Bruno Andreoni, Luca Ansaloni, Giovanni Sgroi, Mario Martinotti, Ildo Scandroglio, Pierluigi Carzaniga, Mauro Longoni, Diego Foschi, Paolo Dionigi, Eugenio Morandi, Mauro Agnello
Article
Oncology
Vincenzo De Giorgi, Marta Grazzini, Silvia Benemei, Niccolo Marchionni, Edoardo Botteri, Elisabetta Pennacchioli, Pierangelo Geppetti, Sara Gandini
Article
Oncology
Carlo Corbellini, Bruno Andreoni, Luca Ansaloni, Giovanni Sgroi, Mario Martinotti, Ildo Scandroglio, Pierluigi Carzaniga, Mauro Longoni, Diego Foschi, Paolo Dionigi, Eugenio Morandi, Mauro Agnello
Article
Oncology
P. M. Webb, R. Na, E. Weiderpass, H. O. Adami, K. E. Anderson, K. A. Bertrand, E. Botteri, T. M. Brasky, L. A. Brinton, C. Chen, J. A. Doherty, L. Lu, S. E. McCann, K. B. Moysich, S. Olson, S. Petruzella, J. R. Palmer, A. E. Prizment, C. Schairer, V. W. Setiawan, A. B. Spurdle, B. Trabert, N. Wentzensen, L. Wilkens, H. P. Yang, H. Yu, H. A. Risch, S. J. Jordan
ANNALS OF ONCOLOGY
(2019)
Article
Gastroenterology & Hepatology
D. Miskovic, J. Ahmed, R. Bissett-Amess, M. Gomez Ruiz, F. Luca, D. Jayne, N. Figueiredo, R. J. Heald, G. Spinoglio, A. Parvaiz, Sergio Alfieri, Shwan Amin, Heiko Aselmann, Paolo Pietro Bianchi, Rogier Crolla, Nicola de'Angelis, Jan Egberts, Roger Gerjy, Marcos Gomez Ruiz, Henrik Loft Jakobson, David Jayne, Ayhan Kuzu, Fabrizio Luca, Benno Mann, Danilo Miskovic, Amjad Parvaiz, Daniel Perez, Fabio Priora, Tero Rautio, Philippe Rouanet, Giuseppe Spinoglio, Niels Thomassen, Alain Valverde, George van der Schelling
COLORECTAL DISEASE
(2019)
Article
Gastroenterology & Hepatology
Kristin Ranheim Randel, Edoardo Botteri, Katrine Maria Kauczynska Romsta, Svein Oskar Frigstad, Michael Bretthauer, Geir Hoff, Thomas de Lange, Oyvind Holme
Article
Dermatology
N. C. Stoer, E. Botteri, R. Ghiasvand, M. Busund, S. Vangen, E. Lund, M. B. Veierod, E. Weiderpass
BRITISH JOURNAL OF DERMATOLOGY
(2019)
Article
Endocrinology & Metabolism
Elisabete Weiderpass, Edoardo Botteri, Joseph C. Longenecker, Abdullah Alkandari, Rihab Al-Wotayan, Qais Al Duwairi, Jaakko Tuomilehto
FRONTIERS IN ENDOCRINOLOGY
(2019)
Article
Oncology
Edoardo Botteri, Nathalie C. Stoer, Elisabete Weiderpass, Eero Pukkala, Olavi Ylikorkala, Heli Lyytinen
CANCER EPIDEMIOLOGY BIOMARKERS & PREVENTION
(2019)
Article
Hematology
Luca Mazzarella, Edoardo Botteri, Anthony Matthews, Elena Gatti, Davide Di Salvatore, Vincenzo Bagnardi, Massimo Breccia, Pau Montesinos, Teresa Bernal, Cristina Gil, Timothy J. Ley, Miguel Sanz, Krishnan Bhaskaran, Francesco Lo Coco, Pier Giuseppe Pelicci
Article
Oncology
Iris Cervenka, Marie Al Rahmoun, Yahya Mahamat-Saleh, Agnes Fournier, Marie-Christine Boutron-Ruault, Gianluca Severi, Saverio Caini, Domenico Palli, Reza Ghiasvand, Marit B. Veierod, Edoardo Botteri, Anne Tjonneland, Anja Olsen, Renee T. Fortner, Rudolf Kaaks, Matthias B. Schulze, Salvatore Panico, Antonia Trichopoulou, Clio Dessinioti, Katerina Niforou, Sabina Sieri, Rosario Tumino, Carlotta Sacerdote, Bas Bueno-de-Mesquita, Torkjel M. Sandanger, Sandra Colorado-Yohar, Maria J. Sanchez, Leire Gil Majuelo, Leila Lujan-Barroso, Eva Ardanaz, Susana Merino, Karolin Isaksson, Salma Butt, Ingrid Ljuslinder, Malin Jansson, Ruth C. Travis, Kay-Tee Khaw, Elisabete Weiderpass, Laure Dossus, Sabina Rinaldi, Marina Kvaskoff
INTERNATIONAL JOURNAL OF CANCER
(2020)
Article
Public, Environmental & Occupational Health
Sunday Oluwafemi Oyeyemi, Tonje Braaten, Edoardo Botteri, Paula Berstad, Kristin Benjaminsen Borch
CLINICAL EPIDEMIOLOGY
(2019)
Article
Oncology
Yuchao Liu, Zijia Liu, Liangyan Zhang, Yuelun Zhang, Ningchen Zhang, Yue Han, Le Shen
Summary: This study found an association between preoperative 6-min walk distance and postoperative complications in patients undergoing laparoscopic gastrointestinal cancer surgery.
Review
Oncology
Matteo Pavone, Rosa Autorino, Nicolo Bizzarri, Giuditta Chilorio, Vincenzo Valentini, Giacomo Corrado, Gabriella Ferrandina, Gabriella Macchia, Maria Antonietta Gambacorta, Giovanni Scambia, Denis Querleu
Summary: Ovarian transposition is an established method for protecting the ovaries from radiation, while surgical procedures for protecting the uterus are still under investigation. This study conducted a systematic review of uterine displacement techniques and performed dose simulation to assess the radiation dose received by the uterus. The results showed that the transposition approach was the most protective.
Article
Oncology
Silvia Ministrini, Maria Bencivenga, Federica Filippini, Gianni Mura, Carlo Milandri, Maria Antonietta Mazzei, Giulio Bagnacci, Mattia Berselli, Manlio Monti, Paolo Morgagni, Leonardo Solaini, Daniele Marrelli, Stefania Piccioni, Stefano De Pascale, Luigina Graziosi, Rossella Reddavid, Fausto Rosa, Claudio Belluco, Guido Tiberio
Summary: The Italian Research Group for Gastric Cancer developed a prospective database to evaluate the impact of a pragmatic attitude on the management of stage IV gastric cancer patients. The study found that different metastatic sites did not affect survival rates, but multiple metastatic sites were associated with worse survival. Patients who could undergo curative resection had better survival rates. A more accurate diagnostic workup and staging had a favorable impact on survival.
Article
Oncology
Luca Lambertini, Fabrizio Di Maida, Anna Cadenar, Samuele Nardoni, Antonio Andrea Grosso, Francesca Valastro, Pietro Spinelli, Riccardo Fantechi, Agostino Tuccio, Gianni Vittori, Andrea Mari, Lorenzo Masieri, Andrea Minervini
Summary: The aim of this study was to evaluate the functional outcomes of Florence intracorporeal neobladder (FloRIN) configuration technique performed with a stentless procedure. The results showed that the stentless procedure was associated with shorter console time and lower estimated blood loss compared to the stent group. There were no significant differences in terms of perioperative features and mid-term functional outcomes between the two groups.
Article
Oncology
Geun-Jeon Kim, Jooin Bang, Hyun-Il Shin, Sang-Yeon Kim, Dong -Il Sun
Summary: This study evaluated the outcome of tonsillar cancer managed with neoadjuvant chemotherapy followed by surgery. The results showed that neoadjuvant chemotherapy reduced tumor volume and pathological adverse features, significantly decreasing the need for adjuvant therapy. A greater reduction in tumor volume predicted a complete pathologic response. There was no significant difference in survival rates between the groups.
Article
Oncology
Alexandra Nassar, Stylianos Tzedakis, Ugo Marchese, Gaanan Naveendran, Remy Sindayigaya, Martin Gaillard, Francois Cauchy, Mickael Lesurtel, Brice Gayet, Olivier Soubrane, David Fuks
Summary: This study identified recurrence between the two stages and a larger tumor size in the future liver remnant as critical factors contributing to the failure of two-stage hepatectomy for bilobar colorectal liver metastases. These findings have important clinical implications for the selection and evaluation of TSH surgery.
Letter
Oncology
Michele Fiore, Gian Marco Petrianni, Gabriele D'Ercole, Pasquale Trecca, Sara Ramella
Review
Oncology
Harry Farrow, Oliver J. Pickering, James A. Gossage, Philip H. Pucher
Summary: The inclusion or exclusion of the thoracic duct in radical esophagectomy for esophageal cancer is a controversial issue. While removing the thoracic duct may increase lymph node yield, it may also lead to higher morbidity without any survival benefit.
Article
Oncology
Xiaokun Li, Siyuan Luan, Chi Zhang, Weili Kong, Xin Xiao, Haowen Zhang, Jianfeng Zhou, Yushang Yang, Yang Xu, Yong Qiang, Pinhao Fang, Yi Shen, Yong Yuan
Summary: This study proposes a new staging system based on ypTNM stage and cN status for early stage ESCC patients after nCRT. The new ypTNM-cN staging system demonstrates superior predictive ability and classification efficacy compared to the AJCC 8th ypTNM staging system. It provides new insights for accurately stratifying ypI stage ESCC patients.