Article
Medicine, Research & Experimental
Kachorn Seresirikachorn, Andrea Sit, Lu Hui Png, Larry Kalish, Raewyn G. G. Campbell, Raquel Alvarado, Richard J. J. Harvey
Summary: Due to the complexity and variety of the frontal recess and sinus anatomy, traditional Draf 2a frontal sinus surgery is challenging. Carolyn's window approach eliminates the limitation of anterior-posterior depth and provides an excellent view of the frontal sinus and recess. The technique achieves successful frontal sinus patency with low morbidities using a 0 degrees endoscope.
Article
Otorhinolaryngology
Andrea Sit, Kachorn Seresirikachorn, Alexander S. Zhang, Joao Mangussi-Gomes, Dichapong Kanjanawasee, Lu Hui Png, Larry Kalish, Raewyn G. Campbell, Raquel Alvarado, Richard J. Harvey
Summary: This study compared the perioperative outcomes and morbidity between endoscopic direct access Draf 2a and angled access Draf 2a. The results showed that direct access Draf 2a, or Carolyn's window, removes the limitation of anteroposterior diameter and has comparable outcomes with angled access Draf 2a in terms of frontal sinus patency and surgical morbidities.
EUROPEAN ARCHIVES OF OTO-RHINO-LARYNGOLOGY
(2023)
Article
Medicine, Research & Experimental
Pedro Plou, Simona Serioli, Alex Y. Alexander, Luciano C. P. C. Leonel, Maria Peris-Celda, Carlos D. Pinheiro-Neto
Summary: In this manuscript, a detailed anatomical description of an eyebrow approach for frontal sinus surgery is presented. The approach allows full exposure of the frontal sinus with preservation of the supraorbital nerve.
Article
Surgery
K. Devaraja, Kailesh Pujary, Suresh Pillai
Summary: Repeated nose blowing can sometimes cause orbital emphysema due to stress fracture or thinning of the orbital wall from osteoma. Our non-surgical management of the fifth reported case highlights nuances in principles of care, emphasizing the role of CT scan and surgical intervention.
JOURNAL OF CRANIOFACIAL SURGERY
(2021)
Article
Otorhinolaryngology
Noor Elyana Ahmad Fawzi, Norhafiza Mat Lazim, Mohd Ezane Aziz, Zahiruddin Wan Mohammad, Baharudin Abdullah
Summary: The study analyzed 400 sides of CTPNS from 200 patients with chronic rhinosinusitis and found that agger nasi cells were the most common frontal cell variants, followed by supra bulla cells and supra bulla frontal cells. Besides agger nasi cells, supraorbital ethmoidal cells and frontal septal cells were significantly associated with the development of frontal sinusitis.
EUROPEAN ARCHIVES OF OTO-RHINO-LARYNGOLOGY
(2022)
Article
Otorhinolaryngology
Steven Kennedy Dennis, Toby O. Steele, Amarbir S. Gill, Joshua C. Hwang, Kamron S. Sarhadi, Karmtej S. Cheema, Sukhkaran S. Aulakh, Machelle D. Wilson, E. Bradley Strong
Summary: This study evaluates radiologic indicators, sinus reaeration rates, and complication rates for nonsurgical treatment of frontal sinus outflow tract fractures. The results show high reaeration rates (91%-98%) and low rates of rescue surgery (2%) and complications (2%), suggesting that nonsurgical management is a viable strategy for nonobstructed fractures. No clear radiographic features were identified to predict sinus reaeration.
OTOLARYNGOLOGY-HEAD AND NECK SURGERY
(2023)
Article
Surgery
Yu Zhao, Jianfeng Liu, Dazhang Yang, Jun Han, Jianhui Zhao, Yibei Wang
Summary: The trans-nasion-complex approach (TNCA) is a safe and direct route for EMLP. Adequate understanding of the nasion complex and mushroom sign will be helpful to complete TNCA.
FRONTIERS IN SURGERY
(2022)
Article
Engineering, Aerospace
Shashi Ranjan Kumar, Dwaipayan Mukherjee
Summary: This article proposes sliding-mode-control-based guidance strategies for a team consisting of aircraft and a defending interceptor against an attacker, based on the line-of-sight guidance concept. The nonlinear framework considered helps circumvent performance degradation under large heading angle errors. The knowledge of the bound on attacker acceleration is shown to be sufficient to ensure interception of an attacking interceptor.
IEEE TRANSACTIONS ON AEROSPACE AND ELECTRONIC SYSTEMS
(2021)
Article
Otorhinolaryngology
T. McHugh, D. D. Sommer, A. Ma ThambooTewfik, K. A. Smith, Tobial McHugh
Summary: This study investigates the availability, usage, and related issues surrounding the use of image guidance systems in endoscopic sinus surgery across Canadian otolaryngology practice settings. Over half of Canadian otolaryngologists have access to image guidance systems, with over 85% of those without access interested in using it if it was made available. Financial barriers are identified as the most important obstacle in obtaining the system.
JOURNAL OF OTOLARYNGOLOGY-HEAD & NECK SURGERY
(2022)
Article
Clinical Neurology
Gianpaolo Jannelli, Francesco Calvanese, Emmanuel Jouanneau, Timothee Jacquesson
Summary: The frontal trans-sinusal approach is a safe and effective alternative for reaching lesions in the anterior skull base. It provides easier access to the olfactory grooves and reduces brain retraction.
ACTA NEUROCHIRURGICA
(2023)
Article
Surgery
Muneera AlKhalifa, Ali Almomen
Summary: The use of image guidance navigation system in endoscopic sinus surgeries improves surgical outcomes, reduces complications, and assists in localizing vital structures.
INDIAN JOURNAL OF OTOLARYNGOLOGY AND HEAD & NECK SURGERY
(2022)
Article
Medicine, General & Internal
Masaki Sawada, Saya Suetake, Hiroshi Yamada, Masaaki Higashino, Susumu Abe, Eiji Tanaka
Summary: This study investigated the impact of orthodontic treatment on the frontal sinus development of adult females. Results showed that orthodontic treatment did not affect frontal sinus development after growth.
JOURNAL OF CLINICAL MEDICINE
(2023)
Article
Otorhinolaryngology
Yu-Hsuan Lin, Po-Fu Chen, Yow-Ling Shiue
Summary: This study presents a successful endoscopic surgical strategy for treating a post-trephination-related frontal sinus cutaneous fistula (FSCF) with complete frontal recess neo-osteogenesis. The strategy involves creating two surgical corridors to establish a patent drainage pathway and prevent orbital and cranial base injuries on the ossified region. Additionally, the procedure offers aesthetic advantages, enables single-stage surgery, and facilitates postoperative wound debridement and surveillance through the drainage pathway.
ENT-EAR NOSE & THROAT JOURNAL
(2023)
Letter
Otorhinolaryngology
Alex C. Tham, Bryan Arthurs, Marc A. Tewfik
Summary: This case report describes a man in his 50s who presented with a painless, progressive sunken appearance of his right eye for 1 year and was subsequently diagnosed with right frontal silent sinus syndrome.
JAMA OTOLARYNGOLOGY-HEAD & NECK SURGERY
(2022)
Article
Environmental Sciences
Liangliang Li, Ming Lv, Zhenhong Jia, Qingxin Jin, Minqin Liu, Liangfu Chen, Hongbing Ma
Summary: In this paper, an effective infrared and visible image fusion method using rolling guidance filtering and gradient saliency map is proposed to solve the problems of brightness and detail information loss in infrared and visible image fusion. The method decomposes the input images into approximate layers and residual layers using rolling guidance filtering; it fuses the approximate layers using an energy attribute fusion model; it introduces the gradient saliency map and constructs corresponding weight matrices to process the residual layers. The fusion image is generated by reconstructing the fused approximate layer sub-image and residual layer sub-images. Experimental results demonstrate the superiority of the proposed infrared and visible image fusion method.
Review
Neurosciences
Adam D. Farmer, Adam Strzelczyk, Alessandra Finisguerra, Alexander Gourine, Alireza Gharabaghi, Alkomiet Hasan, Andreas M. Burger, Andres M. Jaramillo, Ann Mertens, Arshad Majid, Bart Verkuil, Bashar W. Badran, Carlos Ventura-Bort, Charly Gaul, Christian Beste, Christopher M. Warren, Daniel S. Quintana, Dorothea Hammerer, Elena Freri, Eleni Frangos, Eleonora Tobaldini, Eugenijus Kaniusas, Felix Rosenow, Fioravante Capone, Fivos Panetsos, Gareth L. Ackland, Gaurav Kaithwas, Georgia H. O'Leary, Hannah Genheimer, Heidi I. L. Jacobs, Ilse Van Diest, Jean Schoenen, Jessica Redgrave, Jiliang Fang, Jim Deuchars, Jozsef C. Szeles, Julian F. Thayer, Kaushik More, Kristl Vonck, Laura Steenbergen, Lauro C. Vianna, Lisa M. McTeague, Mareike Ludwig, Maria G. Veldhuizen, Marijke De Couck, Marina Casazza, Marius Keute, Marom Bikson, Marta Andreatta, Martina D'Agostini, Mathias Weymar, Matthew Betts, Matthias Prigge, Michael Kaess, Michael Roden, Michelle Thai, Nathaniel M. Schuster, Nicola Montano, Niels Hansen, Nils B. Kroemer, Peijing Rong, Rico Fischer, Robert H. Howland, Roberta Sclocco, Roberta Sellaro, Ronald G. Garcia, Sebastian Bauer, Sofiya Gancheva, Stavros Stavrakis, Stefan Kampusch, Susan A. Deuchars, Sven Wehner, Sylvain Laborde, Taras Usichenko, Thomas Polak, Tino Zaehle, Uirassu Borges, Vanessa Teckentrup, Vera K. Jandackova, Vitaly Napadow, Julian Koenig
Summary: Transcutaneous vagus nerve stimulation (tVNS) is gaining interest in basic, translational, and clinical research due to its non-invasive nature. Future studies need to focus on reporting practices, stimulation parameters, and participant safety to advance the field. Additionally, advancements in animal research may have implications for the application of tVNS in humans.
FRONTIERS IN HUMAN NEUROSCIENCE
(2021)
Article
Neurosciences
Laura J. Arendsen, Robert Guggenberger, Manuela Zimmer, Tobias Weigl, Alireza Gharabaghi
Summary: Low-frequency peripheral electrical stimulation using a matrix electrode modulates spinal nociceptive pathways, with potential effects on cortical oscillatory activity. Motor imagery may influence the effects of PEMS on beta activity. Brain state-dependent PEMS could be a novel approach for the treatment of chronic pain, but further studies are needed to determine optimal stimulation conditions for pain reduction.
FRONTIERS IN NEUROSCIENCE
(2021)
Article
Neurosciences
Kathrin Machetanz, Levan Berelidze, Robert Guggenberger, Alireza Gharabaghi
Summary: Transcutaneous auricular vagus nerve stimulation modulates brain activity and heart function, leading to an increase in heart rate variability. Different stimulation targets induce frequency-specific oscillatory modulation in various cortical areas, with the most prominent changes in the frontal region. Stimulating different auricular locations results in specific patterns of cortical oscillations, highlighting the potential for defining stimulation parameters for therapeutic purposes.
FRONTIERS IN NEUROSCIENCE
(2021)
Article
Clinical Neurology
Kathrin Machetanz, Lasse Wiesinger, Maria Teresa Leao, Marina Liebsch, Leonidas Trakolis, Sophie Wang, Alireza Gharabaghi, Marcos Tatagiba, Georgios Naros
Summary: Conventional time-series parameters may not be reliable descriptors of motor-evoked potentials (MEPs) in brain tumor patients, and frequency domain analysis is suggested instead. The time-frequency representation of MEPs provides additional information about the status of the cortico-spinal motor system and its relation to motor performance.
CLINICAL NEUROPHYSIOLOGY
(2021)
Article
Neurosciences
Maria-Sophie Breu, Marlieke Schneider, Johannes Klemt, Idil Cebi, Alireza Gharabaghi, Daniel Weiss
Summary: This study found increased muscle activation of the alpha and lower beta bands in PD freezers compared to healthy controls, and this was attenuated with STN-DBS, which paralleled the clinical improvement of freezing.
FRONTIERS IN HUMAN NEUROSCIENCE
(2022)
Article
Clinical Neurology
Anne Koy, Andrea A. Kuehn, Julius Huebl, Gerd-Helge Schneider, Anne K. van Riesen, Matthias Eckenweiler, Cornelia Rensing-Zimmermann, Volker Arnd Coenen, Joachim K. Krauss, Assel Saryyeva, Hans Hartmann, Martin Haeussler, Jens Volkmann, Cordula Matthies, Annette Horn, Alfons Schnitzler, Jan Vesper, Alireza Gharabaghi, Daniel Weiss, Andrea Bevot, Warren Marks, Angela Pomykal, Elegast Monbaliu, Guntram Borck, Joerg Mueller, Reinhild Prinz-Langenohl, Till Dembek, Veerle Visser-Vandewalle, Jochen Wirths, Petra Schiller, Martin Hellmich, Lars Timmermann
Summary: DBS treatment may improve quality of life in pediatric patients with pharmacorefractory dyskinetic cerebral palsy, but current evidence is not yet sufficient to recommend it as a routine treatment method, further research is needed.
MOVEMENT DISORDERS
(2022)
Article
Clinical Neurology
Inken Toedt, Bassam Al-Fatly, Oliver Granert, Andrea A. Kuehn, Paul Krack, Joern Rau, Lars Timmermann, Alfons Schnitzler, Steffen Paschen, Ann-Kristin Helmers, Andreas Hartmann, Eric Bardinet, Michael Schuepbach, Michael T. Barbe, Till A. Dembek, Valerie Fraix, Dorothee Kuebler, Christine Brefel-Courbon, Alireza Gharabaghi, Lars Wojtecki, Marcus O. Pinsker, Stephane Thobois, Philippe Damier, Tatiana Witjas, Jean-Luc Houeto, Carmen Schade-Brittinger, Marie Vidailhet, Andreas Horn, Guenther Deuschl
Summary: This study assessed the impact of subthalamic nucleus deep brain stimulation (STN-DBS) on clinical outcomes and quality of life in patients with Parkinson's disease, finding a correlation between the stimulated part of the STN and improvements in symptom control and quality of life.
MOVEMENT DISORDERS
(2022)
Article
Clinical Neurology
Kathrin Machetanz, Florian Grimm, Sophie Wang, Martin U. Schuhmann, Marcos Tatagiba, Alireza Gharabaghi, Georgios Naros
Summary: Robot-assisted, transcerebellar stereotaxy can improve the risk-benefit ratio of brainstem biopsies by avoiding the restrictions of a transfrontal approach and conventional frame-based stereotaxy. Profound registration and anatomical-functional trajectory selection were essential to reduce mortality and morbidity.
NEUROSURGICAL FOCUS
(2022)
Article
Oncology
Miriam Bender, Marcos Tatagiba, Alireza Gharabaghi
Summary: Health-related quality of life (HRQoL) and perceived benefit play important roles in medical decision-making. This study compared HRQoL and perceived benefit in patients undergoing surgical treatment for vestibular schwannoma (VS), and explored the influence of comorbid depression.
FRONTIERS IN ONCOLOGY
(2022)
Editorial Material
Clinical Neurology
Bettina Hanna Trunk, Lukas Ziegler, Alireza Gharabaghi
Article
Neurosciences
Georgios Naros, Kathrin Machetanz, Maria Teresa Leao, Sophie Wang, Marcos Tatagiba, Alireza Gharabaghi
Summary: This study investigated the impact of glial brain tumors on the functional corticospinal integrity and found that conventional MEP features were unreliable in reflecting this impact. Frequency-domain MEP features, on the other hand, provided a better assessment of motor impairment.
HUMAN BRAIN MAPPING
(2022)
Article
Engineering, Biomedical
Robert Guggenberger, Bettina Hanna Trunk, Sine Canbolat, Lukas Ziegler, Alireza Gharabaghi
Summary: This study evaluated the reliability and validity of ipsilateral motor-evoked potentials (iMEP) induced by transcranial magnetic stimulation in healthy adults. The results showed significant variations in iMEP estimation between different algorithms, and template-based approaches may be more valid. This is important for the selection and development of analysis algorithms for magnetically induced potentials.
JOURNAL OF NEURAL ENGINEERING
(2022)
Article
Medicine, Research & Experimental
Agnes Langer, Lara Lucke-Paulig, Lucia Gassner, Rejko Krueger, Daniel Weiss, Alireza Gharabaghi, Heidemarie Zach, Walter Maetzler, Markus A. Hobert
Summary: This study compared the effects of deep brain stimulation and dopaminergic medication on gait parameters in patients with advanced Parkinson disease. The results showed that dopaminergic medication had larger additional effects on gait parameters under both single-tasking and dual-tasking conditions, while deep brain stimulation only improved specific gait parameters.
Article
Neurosciences
Kathrin Machetanz, Florian Grimm, Ruth Schaefer, Leonidas Trakolis, Helene Hurth, Patrick Haas, Alireza Gharabaghi, Marcos Tatagiba, Georgios Naros
Summary: This study introduces a cost-effective custom-made EMG biofeedback system for facial rehabilitation, demonstrating its good application potential in both healthy subjects and patients with facial palsy. There is a correlation between electrophysiological measurements and clinical outcomes.
FRONTIERS IN NEUROSCIENCE
(2022)
Article
Clinical Neurology
Kathrin Machetanz, Florian Grimm, Thomas Wuttke, Josua Kegele, Holger Lerche, Marcos Tatagiba, Sabine Rona, Alireza Gharabaghi, Juergen Honegger, Georgios Naros
Summary: Implantation of insular electrodes via anterior or posterior oblique approach is safe and efficient, covering both anteroposterior and ventrodorsal functional organization with few electrodes. There was no decrease in accuracy with longer trajectory of insular SEEG electrodes compared to noninsular SEEG electrodes, and results of frame-based and robot-assisted implantations were comparable.
JOURNAL OF NEUROSURGERY
(2021)
Article
Oncology
Yuchao Liu, Zijia Liu, Liangyan Zhang, Yuelun Zhang, Ningchen Zhang, Yue Han, Le Shen
Summary: This study found an association between preoperative 6-min walk distance and postoperative complications in patients undergoing laparoscopic gastrointestinal cancer surgery.
Review
Oncology
Matteo Pavone, Rosa Autorino, Nicolo Bizzarri, Giuditta Chilorio, Vincenzo Valentini, Giacomo Corrado, Gabriella Ferrandina, Gabriella Macchia, Maria Antonietta Gambacorta, Giovanni Scambia, Denis Querleu
Summary: Ovarian transposition is an established method for protecting the ovaries from radiation, while surgical procedures for protecting the uterus are still under investigation. This study conducted a systematic review of uterine displacement techniques and performed dose simulation to assess the radiation dose received by the uterus. The results showed that the transposition approach was the most protective.
Article
Oncology
Silvia Ministrini, Maria Bencivenga, Federica Filippini, Gianni Mura, Carlo Milandri, Maria Antonietta Mazzei, Giulio Bagnacci, Mattia Berselli, Manlio Monti, Paolo Morgagni, Leonardo Solaini, Daniele Marrelli, Stefania Piccioni, Stefano De Pascale, Luigina Graziosi, Rossella Reddavid, Fausto Rosa, Claudio Belluco, Guido Tiberio
Summary: The Italian Research Group for Gastric Cancer developed a prospective database to evaluate the impact of a pragmatic attitude on the management of stage IV gastric cancer patients. The study found that different metastatic sites did not affect survival rates, but multiple metastatic sites were associated with worse survival. Patients who could undergo curative resection had better survival rates. A more accurate diagnostic workup and staging had a favorable impact on survival.
Article
Oncology
Luca Lambertini, Fabrizio Di Maida, Anna Cadenar, Samuele Nardoni, Antonio Andrea Grosso, Francesca Valastro, Pietro Spinelli, Riccardo Fantechi, Agostino Tuccio, Gianni Vittori, Andrea Mari, Lorenzo Masieri, Andrea Minervini
Summary: The aim of this study was to evaluate the functional outcomes of Florence intracorporeal neobladder (FloRIN) configuration technique performed with a stentless procedure. The results showed that the stentless procedure was associated with shorter console time and lower estimated blood loss compared to the stent group. There were no significant differences in terms of perioperative features and mid-term functional outcomes between the two groups.
Article
Oncology
Geun-Jeon Kim, Jooin Bang, Hyun-Il Shin, Sang-Yeon Kim, Dong -Il Sun
Summary: This study evaluated the outcome of tonsillar cancer managed with neoadjuvant chemotherapy followed by surgery. The results showed that neoadjuvant chemotherapy reduced tumor volume and pathological adverse features, significantly decreasing the need for adjuvant therapy. A greater reduction in tumor volume predicted a complete pathologic response. There was no significant difference in survival rates between the groups.
Article
Oncology
Alexandra Nassar, Stylianos Tzedakis, Ugo Marchese, Gaanan Naveendran, Remy Sindayigaya, Martin Gaillard, Francois Cauchy, Mickael Lesurtel, Brice Gayet, Olivier Soubrane, David Fuks
Summary: This study identified recurrence between the two stages and a larger tumor size in the future liver remnant as critical factors contributing to the failure of two-stage hepatectomy for bilobar colorectal liver metastases. These findings have important clinical implications for the selection and evaluation of TSH surgery.
Letter
Oncology
Michele Fiore, Gian Marco Petrianni, Gabriele D'Ercole, Pasquale Trecca, Sara Ramella
Review
Oncology
Harry Farrow, Oliver J. Pickering, James A. Gossage, Philip H. Pucher
Summary: The inclusion or exclusion of the thoracic duct in radical esophagectomy for esophageal cancer is a controversial issue. While removing the thoracic duct may increase lymph node yield, it may also lead to higher morbidity without any survival benefit.
Article
Oncology
Xiaokun Li, Siyuan Luan, Chi Zhang, Weili Kong, Xin Xiao, Haowen Zhang, Jianfeng Zhou, Yushang Yang, Yang Xu, Yong Qiang, Pinhao Fang, Yi Shen, Yong Yuan
Summary: This study proposes a new staging system based on ypTNM stage and cN status for early stage ESCC patients after nCRT. The new ypTNM-cN staging system demonstrates superior predictive ability and classification efficacy compared to the AJCC 8th ypTNM staging system. It provides new insights for accurately stratifying ypI stage ESCC patients.