☆ 3.8 Meeting Abstract

Survival in young women diagnosed with breast cancer. Does pregnancy status make a difference?

EJC SUPPLEMENTS (2010)

Journal

EJC SUPPLEMENTS

Volume 8, Issue 3, Pages 206-206

Publisher

PERGAMON-ELSEVIER SCIENCE LTD

DOI: 10.1016/S1359-6349(10)70523-1

Keywords

-

Categories

Oncology

Ask authors/readers for more resources

Protocol

Community support

Reagent

Community support

Authors

I am an author on this paper

Click your name to claim this paper and add it to your profile.

Reviews

Primary Rating

3.8

Not enough ratings

Secondary Ratings

Novelty

-

Significance

-

Scientific rigor

-

Rate this paper

Recommended

Article Oncology

Cancer survival in women diagnosed with pregnancy- associated cancer: An overview using nationwide registry data in Sweden 1970-2018

Anna L. Johansson, Irma Fredriksson, Lene Mellemkjaer, Hanne Stensheim, Paivi Lahteenmaki, Jeanette F. Winther, Gustav J. Ullenhag, Frida E. Lundberg

Summary: This study provides a comprehensive overview of cancer survival in women with pregnancy-associated cancer over five decades. While some types of pregnancy-associated cancer have higher cancer mortality, most sites of pregnancy-associated cancer do not have a significantly worse prognosis compared to non-pregnancy-associated cancer.

EUROPEAN JOURNAL OF CANCER (2021)

Add to Collection

Review Oncology

Receptor status of breast cancer diagnosed during pregnancy: A literature review

Carsten F. J. Bakhuis, Britt B. M. Suelmann, Carmen van Dooijeweert, Sabine Linn, Elsken van der Wall, Paul J. van Diest

Summary: Breast cancer diagnosed during pregnancy (BCdP) is often characterized by ER negative (56.6%), PR negative (57.2%), or both ER and PR negative (47.9%) tumors. Additionally, 33.2% of BCdP patients exhibit HER2-overexpression and 27.6% have triple negative disease. This aggressive profile with frequently HER2 overexpression is distinct from non-pregnant similar-aged patients, highlighting the need for future comparative research.

CRITICAL REVIEWS IN ONCOLOGY HEMATOLOGY (2021)

Add to Collection

Article Oncology

Pregnancy after breast cancer: Results from a prospective cohort of young women with breast cancer

Philip D. Poorvu, Shari I. Gelber, Yue Zheng, Kathryn J. Ruddy, Rulla M. Tamimi, Jeffrey Peppercorn, Lidia Schapira, Virginia F. Borges, Steven E. Come, Matteo Lambertini, Shoshana M. Rosenberg, Ann H. Partridge

Summary: Many young women with newly diagnosed breast cancer express interest in future pregnancies. Within 5 years of diagnosis, 36% reported interest in having children, with the majority successfully conceiving if they attempted to do so. Factors such as age at diagnosis and parity status were associated with likelihood of pregnancy, while endocrine therapy was inversely linked to pregnancy outcomes. Longitudinal fertility discussions are important for this population.

CANCER (2021)

Add to Collection

Article Obstetrics & Gynecology

Disease-free survival does not differ according to fertility preservation technique for young women with breast cancer

Charlotte Sonigo, Noemi Amsellem, Anne Mayeur, Laetitia Laup, Barbara Pistilli, Suzette Delaloge, Florence Eustache, Christophe Sifer, Sophia Rakrouki, Alexandra Benoit, Maeliss Peigne, Michael Grynberg

Summary: The study aimed to investigate the impact of fertility preservation strategies using or not using ovarian stimulation on the long-term disease-free survival of patients with breast cancer. The results showed that ovarian stimulation did not significantly affect disease-free survival but was associated with higher overall survival in breast cancer patients. Overall, the study found that fertility preservation techniques did not impact the disease-free survival and overall survival of young patients with breast cancer.

FERTILITY AND STERILITY (2023)

Add to Collection

Article Oncology

One Size Does Not Fit All: Breast Cancer in Young Women

Lamis Yehia, Charis Eng

Summary: The study of characteristics of breast cancer in young women has important implications for personalized genomics-driven management.

CLINICAL CANCER RESEARCH (2022)

Add to Collection

Article Oncology

Safety of assisted reproductive techniques in young women harboring germline pathogenic variants in BRCA1/2 with a pregnancy after prior history of breast cancer

M. Condorelli, M. Bruzzone, M. Ceppi, A. Ferrari, A. Grinshpun, A. S. Hamy, E. de Azambuja, E. Carrasco, F. A. Peccatori, A. Di Meglio, S. Paluch-Shimon, P. D. Poorvu, M. Venturelli, C. Rousset-Jablonski, C. Senechal, L. Livraghi, R. Ponzone, L. De Marchis, K. Pogoda, A. Sonnenblick, C. Villarreal-Garza, O. Cordoba, L. Teixeira, F. Clatot, K. Punie, R. Graffeo, M. Dieci, J. A. Perez-Fidalgo, F. P. Duhoux, F. Puglisi, A. R. Ferreira, E. Blondeaux, T. Peretz-Yablonski, O. Caron, C. Saule, L. Ameye, J. Balmana, A. H. Partridge, H. A. Azim, I Demeestere, M. Lambertini

Summary: In breast cancer survivors carrying germline BRCA1/2 pathogenic variants, assisted reproductive techniques (ART) may be a safe option when natural conception fails. Patients in the ART group were older and experienced more delivery complications, but there were no apparent differences in other obstetrical outcomes between the two groups.

ESMO OPEN (2021)

Add to Collection

Article Oncology

Impact of Screening Mammography on Treatment in Young Women Diagnosed with Breast Cancer

Shkala Karzai, Elisa Port, Cleo Siderides, Christopher Valente, Soojin Ahn, Erin Moshier, Meng Ru, Kereeti Pisapati, Ronald Couri, Laurie Margolies, Hank Schmidt, Sarah Cate

Summary: This study aimed to assess the association between the frequency of mammography in young women and the extent of surgery and chemotherapy required for breast cancer treatment. The results showed that compared to those screened within 1-24 months, the group who were never screened and the group screened over 25 months prior to diagnosis were more likely to receive chemotherapy and undergo surgery. This suggests that initiating screening mammography at age 40 can help reduce the risk of aggressive treatments for newly diagnosed breast cancers in this age group.

ANNALS OF SURGICAL ONCOLOGY (2022)

Add to Collection

Article Oncology

Prognosis of breast cancer diagnosed during pregnancy and early postpartum according to immunohistochemical subtype: A matched case-control study

Wendy R. Munoz-Montano, Paula Cabrera-Galeana, Cynthia De la Garza-Ramos, Hatem A. Azim, Ariana Tabares, Victor Perez, Fanny Porras Reyes, Daniel Sanchez Benitez, Alberto Alvarado-Miranda, Fernando Lara-Medina, Rafael Vazquez Romo, Enrique Bargallo-Rocha, Oscar Arrieta, Cynthia Villarreal-Garza

Summary: The study found that PABC patients have worse disease-free survival rates, especially in hormone receptor-positive/HER2-negative and HER2-positive diseases. Pregnant and postpartum status independently impact disease-free survival.

BREAST CANCER RESEARCH AND TREATMENT (2021)

Add to Collection

Article Oncology

Somatic and Germline Genomic Alterations in Very Young Women with Breast Cancer

Adrienne G. Waks, Dewey Kim, Esha Jain, Craig Snow, Gregory J. Kirkner, Shoshana M. Rosenberg, Coyin Oh, Philip D. Poorvu, Kathryn J. Ruddy, Rulla M. Tamimi, Jeffrey Peppercorn, Lidia Schapira, Virginia F. Borges, Steven E. Come, Elena F. Brachtel, Ellen Warner, Laura C. Collins, Ann H. Partridge, Nikhil Wagle

Summary: The study identified significant differences in somatic alterations of three genes (PIK3CA, GATA3, and ARID1A) in young versus older women with luminal A breast cancer. Additionally, a portion of young women with breast cancer carried pathogenic germline variants, with BRCA1/2 mutations being the most common. Further investigation into these genetic differences may help improve treatment options for young patients with breast cancer.

CLINICAL CANCER RESEARCH (2022)

Add to Collection

Article Oncology

Reproductive Outcomes After Breast Cancer in Women With vs Without Fertility Preservation

Anna Marklund, Frida E. Lundberg, Sandra Eloranta, Elham Hedayati, Karin Pettersson, Kenny A. Rodriguez-Wallberg

Summary: This study found that fertility preservation at the time of breast cancer diagnosis in women was associated with a significantly higher rate of postdiagnosis live births and assisted reproduction treatments, without any negative impact on overall survival. It highlights the importance of fertility preservation in reproductive counseling for women diagnosed with breast cancer at a young age.

JAMA ONCOLOGY (2021)

Add to Collection

Article Environmental Sciences

Does high-speed rail make firms cleaner in China?

Tao Zhou, Ning Zhang

Summary: This paper examines the impact of China's high-speed rail (HSR) on firms' environmental efficiency using firm level datasets from 2004 to 2014. The results show that HSR construction has contributed to a reduction in firms' SO2 intensity mainly through innovation, productivity improvement, and agglomeration. The effects are more significant for firms in core cities, while firms in peripheral cities seem to be unaffected. Furthermore, dirty firms, state-owned firms, foreign firms, and large firms benefit more from the HSR's environmental efficiency improvements.

JOURNAL OF ENVIRONMENTAL MANAGEMENT (2022)

Add to Collection

Article Oncology

Reproductive risk factors associated with breast cancer in young women by molecular subtype

Kathryn J. Ruddy, Robert A. Vierkant, Nusrat Jahan, Alexandra Higgins, Ann Partridge, Nicole Larson, Derek C. Radisky, Fergus Couch, Janet Olson, Mark E. Sherman

Summary: This study examined the association between detailed features of pregnancy and the postpartum period with early onset breast cancer. The results revealed a higher proportion of triple negative breast cancer among young women with breast cancer, as well as a lower Breast Imaging-Reporting and Data System (BI-RADS) index in parous women with triple negative breast cancer compared to other subtypes. This suggests the need for further research on the relationship between pregnancy-lactation-postpartum involution and breast cancer etiology.

BREAST (2022)

Add to Collection

Article Medicine, General & Internal

Breast surgery for young women with early-stage breast cancer Mastectomy or breast-conserving therapy?

Zhi-Hong Sun, Chuang Chen, Xin-Wen Kuang, Jun-Long Song, Sheng-Rong Sun, Wei-Xing Wang

Summary: This study found that, compared to mastectomy, breast-conserving therapy (BCT) can provide better breast cancer-specific survival and overall survival benefits in young white patients under 40 with early-stage breast cancer, especially in the 36 to 40 years age group.

MEDICINE (2021)

Add to Collection

Article Oncology

Conception and pregnancy among women with a live birth after breast cancer treatment: A survey study of young breast cancer survivors

Kimia Sorouri, Tal Sella, Shoshana M. Rosenberg, Maggie Loucks, Gregory Kirkner, Craig Snow, Kathryn J. Ruddy, Shari I. Gelber, Rulla M. Tamimi, Jeffrey M. Peppercorn, Lidia Schapira, Virginia F. Borges, Steven E. Come, Ellen Warner, Ann H. Partridge

Summary: This study investigated the postcancer conception and pregnancy experience of young BC survivors and found that most of them conceived naturally without negative impact from the history of BC. However, a higher rate of hypertensive disorders of pregnancy was observed, requiring further investigation.

CANCER (2023)

Add to Collection

Article Oncology

Pregnancy-associated breast cancer: does timing of presentation affect outcome?

Angelena Crown, Damian McCartan, Michael A. Curry, Sujata Patil, Sabrina Kamer, Shari Goldfarb, Mary L. Gemignani

Summary: This study evaluates clinicopathologic features, treatments, and clinical outcomes of women diagnosed with stage 0-III pregnancy-associated breast cancer (PABC) between 1992 and 2020. The results show similar clinicopathologic features and treatment delays, as well as similar 10-year recurrence-free survival between women diagnosed during pregnancy and those diagnosed within 12 months postpartum. However, women diagnosed postpartum have higher 10-year overall survival.

BREAST CANCER RESEARCH AND TREATMENT (2023)

Add to Collection

Article Oncology

Priority recommendations for the implementation of patient-reported outcomes in clinical cancer care: a Delphi study

C. Mazariego, M. Jefford, R. J. Chan, N. Roberts, L. Millar, A. Anazodo, S. Hayes, B. Brown, C. Saunders, K. Webber, J. Vardy, A. Girgis, B. Koczwara

Summary: The aim of this study was to develop priority recommendations for the service level implementation of patient-reported outcomes (PROs) into clinical cancer care. A two-round modified Delphi survey was conducted to rank and prioritize statements related to PRO implementation. The results highlighted the importance of clinical relevance, stakeholder engagement, communication, and integration within existing processes and capabilities in implementing PROs in clinical cancer care.

JOURNAL OF CANCER SURVIVORSHIP (2022)

Add to Collection

Article Medicine, General & Internal

Provision of end-of-life care in primary care: a survey of issues and outcomes in the Australian context

Jinfeng Ding, Claire E. Johnson, Christobel Saunders, Sharon Licqurish, David Chua, Geoffrey Mitchell, Angus Cook

Summary: This study investigated the involvement, continuity, and outcomes of end-of-life care provided by general practitioners in Australia. The findings suggest a need for palliative care training and healthcare system reforms to better support GPs in their role in end-of-life care.

BMJ OPEN (2022)

Add to Collection

Review Oncology

Clinical Decision Making in the Management of Breast Cancer Diagnosed During Pregnancy: A Review and Case Series Analysis

Nadom Safi, Christobel Saunders, Antoinette Anazodo, Jan E. Dickinson, Frances Boyle, Angela Ives, Alex Wang, Zhuoyang Li, Elizabeth Sullivan

Summary: This study highlights different management options for breast cancer diagnosed during pregnancy, discussing investigations, treatments, and outcomes for these women. It includes a review of six cases of women diagnosed with breast cancer during pregnancy, illustrating various considerations for different trimesters.

JOURNAL OF ADOLESCENT AND YOUNG ADULT ONCOLOGY (2022)

Add to Collection

Meeting Abstract Oncology

Development of a patient-centered core outcome set for metastatic breast cancer

K. M. de Ligt, B. H. de Rooij, E. Hedayati, M. M. Karsten, V. R. Smaardijk, M. Velting, C. Saunders, L. Travado, F. Cardoso, E. Lopez Ramirez, N. C. Carney, Y. Wengstrom, A. Ives, G. Velikova, M. D. L. Sousa Fialho, L. Koppert, L. V. Van de Poll-Franse

ANNALS OF ONCOLOGY (2022)

Add to Collection

Article Nursing

Perinatal outcomes of women with gestational breast cancer in Australia and New Zealand: A prospective population-based study

Elizabeth Sullivan, Nadom Safi, Zhuoyang Li, Marc Remond, Tina Y. T. Chen, Nasrin Javid, Jan E. Dickinson, Angela Ives, Karin Hammarberg, Antoinette Anazodo, Frances Boyle, Jane Fisher, Lesley Halliday, Greg Duncombe, Claire McLintock, Alex Y. Wang, Christobel Saunders

Summary: This study aimed to investigate the epidemiology, clinical management, and outcomes of women with gestational breast cancer (GBC). The findings showed that patients diagnosed with GBC before 30 weeks of gestation required surgical and systemic cancer treatment during pregnancy, along with planned preterm birth. On the other hand, for patients diagnosed after 30 weeks, cancer treatment was deferred until postdelivery. The study also revealed that 42.5% of preterm babies required higher-level neonatal care, but there were no perinatal deaths or congenital malformations.

BIRTH-ISSUES IN PERINATAL CARE (2022)

Add to Collection

Article Oncology

Rates of reoperation after breast conserving cancer surgery in Western Australia before and after publication of the SSO-ASTRO margins guideline

M. Luke Marinovich, Christobel M. Saunders, Gavin Pereira, Nehmat Houssami

Summary: This study investigated whether the introduction of the 2014 surgical margins guideline was associated with a reduction in reoperation rates for breast cancer patients in Western Australia. The results showed that the post-guideline reoperation rates did decrease, but this decline was already observed before the guideline was introduced.

BREAST (2023)

Add to Collection

Article Biochemistry & Molecular Biology

FANCM missense variants and breast cancer risk: a case-control association study of 75,156 European women

Gisella Figlioli, Amandine Billaud, Thomas U. Ahearn, Natalia N. Antonenkova, Heiko Becher, Matthias W. Beckmann, Sabine Behrens, Javier Benitez, Marina Bermisheva, Marinus J. Blok, Natalia Bogdanova, Bernardo Bonanni, Barbara Burwinkel, Nicola J. Camp, Archie Campbell, Jose E. Castelao, Melissa H. Cessna, Stephen J. Chanock, Kamila Czene, Peter Devilee, Thilo Doerk, Christoph Engel, Mikael Eriksson, Peter A. Fasching, Jonine D. Figueroa, Marike Gabrielson, Manuela Gago-Dominguez, Montserrat Garcia-Closas, Anna Gonzalez-Neira, Felix Grassmann, Pascal Guenel, Melanie Gundert, Andreas Hadjisavvas, Eric Hahnen, Per Hall, Ute Hamann, Patricia A. Harrington, Wei He, Peter Hillemanns, Antoinette Hollestelle, Maartje J. Hooning, Reiner Hoppe, Anthony Howell, Keith Humphreys, Agnes Jager, Anna Jakubowska, Elza K. Khusnutdinova, Yon-Dschun Ko, Vessela N. Kristensen, Annika Lindblom, Jolanta Lissowska, Jan Lubinski, Arto Mannermaa, Siranoush Manoukian, Sara Margolin, Dimitrios Mavroudis, William G. Newman, Nadia Obi, Mihalis Panayiotidis, Muhammad U. Rashid, Valerie Rhenius, Matti A. Rookus, Emmanouil Saloustros, Elinor J. Sawyer, Rita K. Schmutzler, Mitul Shah, Reijo Sironen, Melissa C. Southey, Maija Suvanto, Rob A. E. M. Tollenaar, Ian Tomlinson, Therese Truong, Lizet E. van der Kolk, Elke M. van Veen, Barbara Wappenschmidt, Xiaohong R. Yang, Manjeet K. Bolla, Joe Dennis, Alison M. Dunning, Douglas F. Easton, Michael Lush, Kyriaki Michailidou, Paul D. P. Pharoah, Qin Wang, Muriel A. Adank, Marjanka K. Schmidt, Irene L. Andrulis, Jenny Chang-Claude, Heli Nevanlinna, Georgia Chenevix-Trench, D. Gareth Evans, Roger L. Milne, Paolo Radice, Paolo Peterlongo

Summary: Evidence from the BRIDGES study suggests that germline protein truncating variants (PTVs) in FANCM are associated with increased risk of ER-negative and triple-negative breast cancer (TNBC), particularly for those with a family history. This study further investigates the association between FANCM missense variants (MVs) and breast cancer risk using the BRIDGES study, analyzing a total of 689 MVs. The results indicate that FANCM MVs may be low/moderate risk factors for ER-negative and TNBC subtypes of breast cancer.

EUROPEAN JOURNAL OF HUMAN GENETICS (2023)

Add to Collection

Article Surgery

Iodine-125 seed versus hook-wire guided breast conserving surgery: do post operative complication rates differ?

Wei Ling Ooi, Brenno Becker, Michael Phillips, Christobel Saunders, Donna Taylor

Summary: This study compared the post-operative complication rates and safety profiles of Radio-guided occult lesion localisation using iodine 125 seeds (ROLLIS) and hook-wire localisation (HWL) for breast conserving surgery. The results showed similar complication rates between the two methods, suggesting that ROLLIS can be used as an alternative with demonstrated superiority and efficacy.

ANZ JOURNAL OF SURGERY (2023)

Add to Collection

Article Oncology

Alternative methods to measure breast density in younger women

Rachel Lloyd, Sarah Pirikahu, Jane Walter, Gemma Cadby, Ellie Darcey, Dilukshi Perera, Martha Hickey, Christobel Saunders, Karol Karnowski, David D. Sampson, John Shepherd, Lothar Lilge, Jennifer Stone

Summary: This study examines the acceptability and performance of two alternative breast density measures, Optical Breast Spectroscopy (OBS) and Dual X-ray Absorptiometry (DXA), in women aged 18-40. The results showed that over 93% of participants deemed OBS and DXA to be acceptable. The correlation between OBS-%water + collagen and %FGV was 0.48, and age and BMI were associated with breast density measures.

BRITISH JOURNAL OF CANCER (2023)

Add to Collection

Correction Radiology, Nuclear Medicine & Medical Imaging

Accuracy and precision of contrast enhanced mammography versus MRI for predicting breast cancer size: how good are they really? (vol 96, 20211172, 2023)

Donna Blanche Taylor, Sally Burrows, Benjamin Frederik Dessauvagie, Christobel Mary Saunders, Angela Ives

Summary: This study evaluates and compares the accuracy and precision of contrast-enhanced mammography (CEM) and MRI in predicting the size of breast cancer, and finds that neither CEM nor MRI can change planned treatment without needle biopsy confirmation.

BRITISH JOURNAL OF RADIOLOGY (2023)

Add to Collection

Article Radiology, Nuclear Medicine & Medical Imaging

Localisation accuracy with iodine-125 seed versus wire guidance for breast cancer surgery

Shoba Ratnagobal, Donna Taylor, Anita G. Bourke, Meredith Kessell, Carolyn Madeley, Melanie C. Robert, Philip Vlaskovsky, Christobel Saunders

Summary: Iodine-125 seeds can be more precise than hook wires for preoperative lesion localisation, but there was no significant difference in re-excision rates.

JOURNAL OF MEDICAL RADIATION SCIENCES (2023)

Add to Collection

Article Radiology, Nuclear Medicine & Medical Imaging

Contrast-enhanced mammography (CEM) versus MRI for breast cancer staging: detection of additional malignant lesions not seen on conventional imaging

Donna B. Taylor, Sally Burrows, Christobel M. Saunders, Paul M. Parizel, Angela Ives

Summary: Contrast-enhanced mammography (CEM) and MRI were compared for assessing disease extent in women with invasive breast cancer. The study found that MRI detected malignant lesions at a slightly higher rate than CEM, especially for occult foci of malignancy.

EUROPEAN RADIOLOGY EXPERIMENTAL (2023)

Add to Collection

Review Oncology

What are the most effective exercise, physical activity and dietary interventions to improve body composition in women diagnosed with or at high-risk of breast cancer? A systematic review and network meta-analysis

Christine Kudiarasu, Pedro Lopez, Daniel A. Galvao, Robert U. Newton, Dennis R. Taaffe, Lorna Mansell, Brianna Fleay, Christobel Saunders, Caitlin Fox-Harding, Favil Singh

Summary: This systematic review and network meta-analysis found that multimodal exercise and diet programs were the most effective interventions to reduce fat mass, body fat percentage, and body weight and increase and/or preserve lean mass in women diagnosed with or at high risk of breast cancer.

CANCER (2023)

Add to Collection

Article Optics

In vivo optical coherence tomography attenuation imaging of the breast surgical cavity using a handheld probe

Peijun Gong, Ken Y. Foo, Devina D. Lakhiani, Renate Zilkens, Hina M. Ismail, Chris Yeomans, Benjamin F. Dessauvagie, Bruce Latham, Christobel M. Saunders, Brendan F. Kennedy

Summary: To aid in the accurate removal of cancer cells during breast-conserving surgery, researchers have developed a handheld optical coherence tomography (OCT) probe and attenuation imaging method, which allows real-time imaging of the surgical cavity. Through experimental validation, this method has been shown to provide accurate and repeatable imaging, and offers an additional tissue contrast mechanism to assist in the identification and removal of cancer cells during breast-conserving surgery.

OPTICS AND LASER TECHNOLOGY (2023)

Add to Collection

Article Optics

Stereoscopic optical palpation for tumour margin assessment in breast-conserving surgery

Qi Fang, Seokhyun Choi, Aiden Taba, Devina D. Lakhiani, Kyle Newman, Renate Zilkens, Rowan W. Sanderson, Benjamin F. Dessauvagie, Christobel M. Saunders, Brendan F. Kennedy

Summary: Optical palpation is a new emerging technique that uses an optical imaging system to generate images of mechanical contrast in tissue. A camera-based optical palpation system, called stereoscopic optical palpation (SOP), is proposed in this paper to directly map the strain of a compliant layer placed on top of the tissue. With SOP, a strain sensitivity of 4.2 m is achieved, which is a 24-fold improvement over previous camera-based optical palpation techniques. SOP has the potential for rapid and reliable imaging, and could be used for tumor margin assessment in breast-conserving surgery.

OPTICS AND LASERS IN ENGINEERING (2023)

Add to Collection

No Data Available

© Peeref 2019-2024. All rights reserved.