Article
Health Care Sciences & Services
Andreea-Daniela Meca, Adina Turcu-Stiolica, Elena Camelia Stanciulescu, Ana Marina Andrei, Floarea Mimi Nitu, Ileana Monica Banita, Marius Matei, Catalina-Gabriela Pisoschi
Summary: Tuberculosis is a global infectious disease with a complex pathogenesis. Recent studies have shown changes in oxidative parameters and antioxidant status in TB patients after anti-tubercular therapy. Monitoring TB based on oxidative stress and antioxidant status may be beneficial in disease management and progression.
JOURNAL OF PERSONALIZED MEDICINE
(2021)
Article
Biochemistry & Molecular Biology
Piotr Dziechciarz, Aneta Strachecka, Grzegorz Borsuk, Krzysztof Olszewski
Summary: Honeybee nests built without man-made wax foundation show more variability in cell widths/sizes compared to commercially-kept colonies. The effects of this natural variability on individual and colony traits have not been explained. Investigating this problem can provide new insights into the biology, physiology, and possibly evolution of honeybees.
Review
Marine & Freshwater Biology
Martin Gabriel Frias-Espericueta, Juan Carlos Bautista-Covarrubias, Carmen Cristina Osuna-Martinez, Carolina Delgado-Alvarez, Carolina Bojorquez, Marisela Aguilar-Juarez, Sarahi Roos-Munoz, Isidro Osuna-Lopez, Federico Paez-Osuna
Summary: Aquatic decapod crustaceans exhibit varied antioxidant defense strategies in response to metal-induced oxidative stress. Antioxidant enzymes may be induced or inhibited by metals depending on species, concentration, and exposure time. Superoxide dismutase, for example, shows increased activity at low metal levels and exposure durations, but is inhibited at higher concentrations and longer exposure times.
AQUATIC TOXICOLOGY
(2022)
Article
Environmental Sciences
Nanik Retno Buwono, Yenny Risjani, Agoes Soegianto
Summary: The study revealed that the digestive tract exhibited more significant antioxidant responses to microplastic contamination compared to the gills. The levels of SOD and MDA in the gills were directly affected by the abundance of microplastics, while the levels of SOD and CAT in the digestive tract were directly influenced by the quantity of microplastics.
Article
Biochemistry & Molecular Biology
Nayely Leyva-Lopez, Melissa Peraza-Arias, Anaguiven Avalos-Soriano, Crisantema Hernandez, Cynthia E. Lizarraga-Velazquez, J. Basilio Heredia
Summary: Polyphenolic extracts from spent coffee grounds exhibit antioxidative protective effects against oxidative stress in C. viridis brain cells by enhancing antioxidant enzyme activity and reducing lipid peroxidation.
Review
Chemistry, Analytical
Nguyen Thi My Thao, Hoang Dang Khoa Do, Nguyen Nhat Nam, Nguyen Khoi Song Tran, Thach Thi Dan, Kieu The Loan Trinh
Summary: Antioxidant nanozymes have emerged as promising materials to replace natural antioxidant enzymes due to their stability, cost savings, and flexible design. This review discusses the mechanisms and manipulation strategies of antioxidant nanozymes, as well as their potential applications in medicine and healthcare. Overall, this review provides useful information for the further development and application of antioxidant nanozymes.
Article
Chemistry, Applied
Mariana de Morais Sousa, Rosalia Maria Lima, Alessandro de Lima, Antonielly Campinho Reis, Ana Amelia de Carvalho Melo Cavalcante, Jose Augusto Gasparotto Gasparotto Sattler, Ligia Bicudo de Almeida-Muradian, Jose de Sousa Lima Neto, Regilda Saraiva dos Reis Moreira-Araujo, Nadir do Nascimento Nogueira
Summary: Jambolan pulp is rich in antioxidant polyphenols, and the study investigated changes in polyphenols and antioxidant capacity during in vitro digestion and chemical extraction. The research found that the digestion process enhances the release of bio-polyphenols with preventive, scavenger, and reparative antioxidant action, which modulate the antioxidant enzymes of S. cerevisiae.
Review
Chemistry, Multidisciplinary
Namrata Singh, G. R. Sherin, Govindasamy Mugesh
Summary: Nanozymes, nanomaterials with enzyme-mimicking activity, have attracted significant interest in biomedical applications, particularly in oxidative stress-mediated disorders. The challenge lies in designing nanozymes that can selectively differentiate between physiological oxidative stress and pathological oxidative stress and mediate appropriate redox reactions in cells, tissues, and organs. This review summarizes the advancements in redox-active nanozymes and their therapeutic significance in various disease models, such as cancer, neurodegeneration, and cardiovascular diseases. It also discusses the future prospects and challenges associated with the biomedical applications of nanozymes.
ANGEWANDTE CHEMIE-INTERNATIONAL EDITION
(2023)
Article
Agronomy
Ji Won Seo, Da Ye Ham, Jae Geun Lee, Na Young Kim, Myong Jo Kim, Chang Yeon Yu, Eun Soo Seong
Summary: This study explored the antioxidant activity of sorghum seeds collected from five countries and identified genetic resources with high antioxidant activity. The results showed that sorghum seeds contained high levels of total phenolic and flavonoid compounds. Several phenolic compounds were identified, with taxifolin being the most abundant. The expression levels of antioxidant genes were also analyzed, with some genetic resources showing higher expression levels. These findings indicate that sorghum can be considered as a biomaterial derived from natural resources.
Article
Engineering, Environmental
Falin He, Qiang Liu, Mingyang Jing, Jingqiang Wan, Chengqian Huo, Wansong Zong, Jingchun Tang, Rutao Liu
Summary: Phenanthrene (PHE) is a significant organic compound found widely in soil, which can induce oxidative stress and cytotoxicity in earthworm coelomocytes at high concentrations. The interaction between PHE and antioxidant enzymes SOD/CAT plays a role in these toxic effects.
JOURNAL OF HAZARDOUS MATERIALS
(2021)
Article
Green & Sustainable Science & Technology
Santosh Jathar, Sanabil Dakhni, Disha Shinde, Abigail Fernandes, Pamela Jha, Neetin Desai, Tareeka Sonawane, Renitta Jobby
Summary: Chlorination is widely used for disinfecting drinking water, but chlorine-resistant bacteria are a concern. This study investigated the antioxidant profile of chlorine-resistant isolates and found differences both between and within species. Antioxidant enzymes may be one mechanism of protection against oxidative stress from chlorination, resulting in chlorine resistance. Understanding the mechanism of chlorine resistance is crucial for identifying potential solutions.
Article
Plant Sciences
Marina Voloshina, Vishnu D. Rajput, Tatiana Minkina, Evgeniy Vechkanov, Saglara Mandzhieva, Mahmoud Mazarji, Ella Churyukina, Andrey Plotnikov, Maria Krepakova, Ming Hung Wong
Summary: This study investigated the toxic effects of zinc oxide nanoparticles (ZnO NPs) on spring barley and found that ZnO NPs may inhibit the growth of spring barley by modulating oxidative stress and antioxidant enzyme metabolism.
Article
Environmental Sciences
Zhihan Cui, Falin He, Xiangxiang Li, Yuze Li, Chengqian Huo, Hao Wang, Yuntao Qi, Guang Tian, Wansong Zong, Rutao Liu
Summary: This study reveals the response mechanisms of SOD/CAT under the regulation of TCC-induced oxidative stress and sheds new light on the toxic pathways of exogenous pollutants on antioxidant-related proteins function.
SCIENCE OF THE TOTAL ENVIRONMENT
(2023)
Article
Engineering, Biomedical
Sushant Singh, Udit Kumar, David Gittess, Tamil S. Sakthivel, Balaashwin Babu, Sudipta Seal
Summary: Nanoceria (CNPs) have shown the ability to act as regenerative ROS scavengers with potential SOD or CAT mimicry, influenced by the Ce3+/Ce4+ ratio. The presence of phosphate can reduce SOD mimetic activity, highlighting the importance of maintaining both SOD and catalase activity in a phosphate-rich environment. Characterization of CNPs in this study demonstrated good biocompatibility and efficient reduction of hydrogen peroxide under in-vitro conditions.
JOURNAL OF BIOMATERIALS APPLICATIONS
(2021)
Article
Horticulture
Mohammad Pourebrahimi, Saeid Eshghi, Asghar Ramezanian, Shiva Faghih
Summary: High salinity levels can lead to various adverse effects on plants, including osmotic stress and nutritional disorders. In this study, the combined use of hydrogen sulfide and selenium compounds was found to alleviate the negative effects of salt stress on strawberry yield and enhance the antioxidant and nutritional quality of the fruits.
SCIENTIA HORTICULTURAE
(2023)
Article
Biochemistry & Molecular Biology
Beata Koim-Puchowska, Grzegorz Klosowski, Joanna Maria Drozdz-Afelt, Dawid Mikulski, Alicja Zielinska
Summary: The study found that under suitable culture conditions, Bacillus subtilis natto BS19 can efficiently synthesize surfactin using starch as the carbon source and yeast extract as the nitrogen source. Potato peelings were proven to be an effective waste substrate, enhancing the biosynthesis of surfactin.
Article
Environmental Sciences
Joanna Maria Drozdz-Afelt, Beata Barbara Koim-Puchowska, Piotr Kaminski
Summary: The study aimed to analyze antioxidant enzyme activity and malondialdehyde concentration in prostate cancer, finding a significant decrease in superoxide dismutase activity, which may be due to a deficiency in the antioxidant defense system.
ENVIRONMENTAL SCIENCE AND POLLUTION RESEARCH
(2022)
Article
Urology & Nephrology
Rafal Donderski, Joanna Szczepanek, Natalia Naruszewicz, Renata Naruszewicz, Andrzej Tretyn, Natalia Skoczylas-Makowska, Janusz Tyloch, Grazyna Odrowaz-Sypniewska, Jacek Manitius
Summary: This study aimed to investigate the role of several miRNAs as markers of kidney damage by analyzing samples from chronic kidney disease patients and healthy controls, with results showing differential expression of certain miRNAs in urine and serum.
INTERNATIONAL UROLOGY AND NEPHROLOGY
(2022)
Editorial Material
Nutrition & Dietetics
Grazyna Sypniewska, Stefan Kruszewski
Article
Nutrition & Dietetics
Wojciech J. Bilinski, Lukasz Szternel, Joanna Siodmiak, Przemyslaw T. Paradowski, Krzysztof Domagalski, Grazyna Sypniewska
Summary: Both vitamin D and insulin-like growth factor 1 play important roles in bone metabolism, and their interaction may influence bone turnover markers in prepubertal children. Low levels of 25-hydroxyvitamin D do not significantly impact bone turnover, and it may not be a reliable predictor of bone metabolism in children. Further research is needed to understand the specific mechanisms underlying the relationship between vitamin D, IGF-1, and bone turnover markers.
Article
Medicine, General & Internal
Maciej Banach, Pawl Burchardt, Krzysztof Chlebus, Piotr Dobrowolski, Dariusz Dudek, Krzysztof Dyrbus, Mariusz Gasior, Piotr Jankowski, Jacek Jozwiak, Longina Klosiewicz-Latoszek, Irina Kowalska, Maciej Malecki, Aleksander Prejbisz, Michat Rakowski, Jacek Rysz, Bogdan Solnica, Dariusz Sitkiewicz, Grazyna Sygitowicz, Grazyna Sypniewska, Tomasz Tomasik, Adam Windak, Dorota Zozulinska-Ziolkiewicz, Barbara Cybulska
ARCHIVES OF MEDICAL SCIENCE
(2021)
Article
Ecology
Robert Lamparski, Karol Kotwica, Daniel Modnicki, Maciej Balcerek, Beata Koim-Puchowska
Summary: The study found that injury to wheat plants affects the feeding and development of Oulema melanopus, with the pest species preferring wheat previously uninjured. The application of effective microorganisms and biostimulant Asahi SL was found to be a secondary factor compared to previous wheat injury. In choice tests, O. melanopus preferred feeding on plants unprovided with treatments.
ARTHROPOD-PLANT INTERACTIONS
(2021)
Article
Endocrinology & Metabolism
Wojciech J. Bilinski, Lukasz Szternel, Joanna Siodmiak, Magdalena Krintus, Przemyslaw T. Paradowski, Krzysztof Domagalski, Grazyna Sypniewska
Summary: The study found that impaired regulation of glucose metabolism and insulin resistance in childhood have adverse effects on bone turnover, particularly on bone resorption. Hyperglycemia significantly decreased bone resorption marker levels in boys but had no effect on girls, who showed higher bone formation than resorption. Insulin resistance significantly decreased bone resorption, especially in girls.
JOURNAL OF DIABETES AND ITS COMPLICATIONS
(2021)
Article
Nutrition & Dietetics
Karolina Murawska, Magdalena Krintus, Magdalena Kuligowska-Prusinska, Lukasz Szternel, Anna Stefanska, Grazyna Sypniewska
Summary: In non-diabetic adults, serum ANGPTL3 and ANGPTL8 show gender-specific relationships with atherogenic lipid biomarkers and obesity, with different effects on cardiovascular risk and hypertriglyceridemia. Sex differences should be considered in the application of therapies using angiopoietin-like proteins inhibitors for dyslipidemia treatment.
Article
Nutrition & Dietetics
Wojciech J. Bilinski, Anna Stefanska, Lukasz Szternel, Katarzyna Bergmann, Joanna Siodmiak, Magdalena Krintus, Przemyslaw T. Paradowski, Grazyna Sypniewska
Summary: The associations between individual components of metabolic syndrome (MetS) and bone health in children are complex, and data on this topic are sparse and inconsistent. In prepubertal girls, insulin resistance exerts a dominant negative impact on bone resorption, and inflammation factor CRP is weakly related to bone resorption in girls.
Article
Biochemistry & Molecular Biology
Justyna Kubacka, Magdalena Staniszewska, Ilona Sadok, Grazyna Sypniewska, Anna Stefanska
Summary: This study investigated the relationship between tryptophan and the metabolites of the kynurenine pathway and the occurrence of type 2 diabetes and metabolic risk factors in obese middle-aged women. The results showed that women with type 2 diabetes had higher levels of tryptophan, kynurenic acid, Kyna/QA ratio, and Kyna/3HKyn ratio than women with normal glycemic levels. Logistic regression analysis showed that the concentrations of tryptophan and kynurenic acid and the values of the Kyna/3HKyn ratio were strongly associated with the occurrence of type 2 diabetes.
Article
Biochemistry & Molecular Biology
Anna Stefanska, Katarzyna Bergmann, Magdalena Krintus, Magdalena Kuligowska-Prusinska, Karolina Murawska, Grazyna Sypniewska
Summary: This study found that ANGPTL8 predicts early triglyceride elevation better than ANGPTL3, especially in postmenopausal women. The association of ANGPTL3 with triglyceride levels is weaker than ANGPTL8 and depends on menopausal status. Therefore, the choice of treatment for dyslipidemia with inhibitors of angiopoietin-like proteins may depend on menopausal status.
Article
Biochemistry & Molecular Biology
Katarzyna Bergmann, Anna Stefanska, Magdalena Krintus, Lukasz Szternel, Mauro Panteghini, Grazyna Sypniewska
Summary: This study assessed the association between fasting and postprandial liver enzyme levels with MetS and elevated HbA1c in children aged 9-11. The results showed that postprandial GGT changes predicted the occurrence of MetS, while postprandial ALT changes predicted prediabetes in prepubertal children.
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
(2023)
Article
Biochemistry & Molecular Biology
Grzegorz Klosowski, Beata Koim-Puchowska, Joanna Drozdz-Afelt, Dawid Mikulski
Summary: This study investigated the response mechanisms of yeast cells to mycotoxins and found that the growth of yeast biomass was inhibited at different concentrations of toxins. The level of malondialdehyde increased, and the expression of heat shock proteins varied depending on the mycotoxin used.
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
(2023)
Meeting Abstract
Biochemistry & Molecular Biology
Iwona Adamczyk, Agnieszka Pater, Rafal Rola, Elena Sinkiewicz-Darol, Aneta Mankowska-Cyl, Magdalena Twaruzek, Grazyna Sypniewska