Review
Chemistry, Applied
Utkarsh Jain, Kirti Saxena, Vinita Hooda, Sapna Balayan, Amar Pal Singh, Mayukh Tikadar, Nidhi Chauhan
Summary: The use of organophosphates and carbamates pesticides poses a threat to human health and the environment, necessitating the monitoring of pesticide residues in food and soil for sensitive detection. Electrochemical biosensors offer a solution to overcome the limitations of conventional detection techniques, providing higher sensitivity, faster detection, reliability, and ease of use for pesticide detection.
Article
Environmental Sciences
Danial Abdollahdokht, Gholamreza Asadikaram, Moslem Abolhassani, Hossein Pourghadamyari, Mojtaba Abbasi-Jorjandi, Sanaz Faramarz, Mohammad Hadi Nematollahi
Summary: The study evaluated the exposure of organophosphate pesticides (OPPs) and organochlorine pesticides (OCPs) in farmworkers' children aged 6 to 11 years in Jiroft city in southeastern Iran, finding harmful effects on the participants.
ENVIRONMENTAL SCIENCE AND POLLUTION RESEARCH
(2021)
Review
Environmental Sciences
Vahulabaranan Rajagopalan, Swethaa Venkataraman, Devi Sri Rajendran, Vaidyanathan Vinoth Kumar, Vaithyanathan Vasanth Kumar, Gayathri Rangasamy
Summary: Neurotoxic pesticides pose a severe threat to humans and the environment, accumulating in the food chain and persisting in the environment to cause long-term exposure and adverse effects on non-target organisms. Accurate and reliable detection of these pesticides and associated neurotransmitters is crucial for clinical applications. Acetylcholinesterase (AchE) biosensors have emerged as a sensitive tool for electrochemical detection, showcasing tremendous potential in various fields.
ENVIRONMENTAL RESEARCH
(2023)
Review
Engineering, Environmental
Archana Mishra, Jitendra Kumar, Jose Savio Melo, Bhanu Prakash Sandaka
Summary: Dichlorvos is an organophosphate pesticide widely used in agriculture and industry, but its indiscriminate use can have harmful effects on the environment and human health. Research on detecting and monitoring dichlorvos has mainly focused on the past three decades, particularly in food, environment, and agriculture.
JOURNAL OF ENVIRONMENTAL CHEMICAL ENGINEERING
(2021)
Article
Engineering, Environmental
Annamalai Yamuna, Natarajan Karikalan, Jun-Hee Na, Tae Yoon Lee
Summary: This study presents a rapid and sensitive electrochemical detection method for carbaryl (CRBL) based on a pyrochlore-type lanthanum tin oxide (LSO) nanoparticles (NPs) modified screen-printed carbon electrode (SPCE). The LSO NPs/SPCE exhibited good electroanalytical performance for CRBL detection, with low detection limit and high selectivity among interfering pesticides. The sensor showed high recovery in detecting CRBL in soil, water, and vegetable samples, proving its suitability for rapid detection of CRBL.
JOURNAL OF HAZARDOUS MATERIALS
(2022)
Article
Environmental Sciences
Karoline Felisbino, Nathalia Kirsten, Shayane da Silva Milhorini, Isabela Saragioto Marcal, Karina Bernert, Rafaela Schiessl, Leticia Nominato-Oliveira, Izonete Cristina Guiloski
Summary: This study evaluated the acute toxicity, teratogenic effects, oxidative stress, and neurotoxicity of Dicamba in zebrafish embryos. The results showed that Dicamba could cause developmental delay, teratogenic effects, and oxidative stress. These findings highlight the potential risks of Dicamba exposure during embryonic development and the need for further studies.
ENVIRONMENTAL POLLUTION
(2023)
Article
Environmental Sciences
Dileshwar Kumar, Sukesh Narayan Sinha, Sangaraju Rajendra, Kanika Sharma
Summary: This cross-sectional study aimed to assess the adverse effects of pesticide use in humans, such as non-communicable diseases, using acetylcholinesterase (AChE) and pesticide concentrations in blood samples. Various health risks from pesticide exposure were assessed, including dizziness or headache, tension, anxiety, confusion, loss of appetite, loss of balance, concentration difficulties, irritability, anger, and depression. A total of 26 pesticides were detected in the blood samples, and the pesticide concentrations were statistically significant between the case and control groups. The AChE levels were significantly lower in case samples than in controls, and were associated with diseases like Alzheimer's, Parkinson's, and obesity.
SCIENCE OF THE TOTAL ENVIRONMENT
(2023)
Article
Spectroscopy
Yingfeng Qin, Gaojie Ye, Hao Liang, Ming Li, Jingjin Zhao
Summary: A novel amplified fluorescence polarization biosensor was developed for highly sensitive detection of organophosphorus pesticides using MnO2 nanosheets as the signal enhancer. The method efficiently suppresses AChE activity and decomposes MnO2 nanosheets to enhance FP signal, tremendously improving the sensitivity of detection for OPs such as diazinon.
SPECTROCHIMICA ACTA PART A-MOLECULAR AND BIOMOLECULAR SPECTROSCOPY
(2022)
Article
Biochemistry & Molecular Biology
Vesna Pehar, Dora Kolic, Antonio Zandona, Goran Sinko, Maja Katalinic, Visnja Stepanic, Zrinka Kovarik
Summary: This study compared 346 herbicides currently in use and 163 no longer in use with cholinesterase inhibitors and drugs in terms of their physicochemical profile and estimated toxic effects on human health. The results showed potential adverse consequences for each herbicide class, with the classes K1, K3/N, F1, and E having the most toxic warnings. In vitro tests revealed that the organophosphate anilofos and oxyacetanilide flufenacet were the most potent inhibitors of acetylcholinesterase and butyrylcholinesterase, respectively. Some herbicides also exhibited cytotoxicity towards hepatocytes and neuroblastoma cells.
CHEMICO-BIOLOGICAL INTERACTIONS
(2023)
Article
Engineering, Environmental
Meng Shien Goh, Su Datt Lam, YaFeng Yang, Mohd Naqiuddin, Siti Nor Khadijah Addis, Wilson Thau Lym Yong, Vijitra Luang-In, Christian Sonne, Nyuk Ling Ma
Summary: The use of chemical pesticides in agriculture is convenient and effective, but may pose risks to human health and the environment through residue contamination. Developing biosensors for on-site detection and promoting alternative pesticides like biopesticides and nanopesticides are recommended, though safety assessments are essential. Reversing pesticide application trends based on changing climate conditions is urgent for sustainable farming practices.
JOURNAL OF HAZARDOUS MATERIALS
(2021)
Article
Environmental Sciences
Raquel Aparecida Moreira, Cristiano V. M. Araujo, Thandy Junio da Silva Pinto, Lais Conceicao Menezes da Silva, Bianca Veloso Goulart, Natalia Prudencio Viana, Cassiana Carolina Montagner, Marisa Narciso Fernandes, Evaldo Luiz Gaeta Espindola
Summary: This study investigated the toxicity mechanisms of two commonly used pesticides in Brazilian sugarcane production (fipronil and 2,4-D) on zebrafish and serpae tetra, including their swimming behavior and neurotoxic effects. The results indicated that these pesticides impact fish avoidance behavior and neuroactivity.
Article
Biophysics
Duy Khiem Nguyen, Chang-Hyun Jang
Summary: In this study, a capillary-sensing platform based on liquid crystals confined in microcapillaries was developed for the detection of acetylcholinesterase (AChE) and its inhibitors. The LC droplets displayed distinct optical images in response to the presence or absence of AChE and AChE-inhibiting pesticides, enabling highly sensitive detection of pesticides. This LC-based microcapillary sensor shows great promise for simple, rapid, and label-free detection of pesticides in environmental samples.
COLLOIDS AND SURFACES B-BIOINTERFACES
(2021)
Article
Chemistry, Applied
Ruijie Fu, Yiwen Wang, Yanlin Liu, Haoran Liu, Qiyang Zhao, Yaohai Zhang, Chengqiu Wang, Zhixia Li, Bining Jiao, Yue He
Summary: In this study, a sensitive fluorescent assay for detection of organophosphorus pesticides (OPs) based on activating the CRISPR-Cas12a system is proposed. By utilizing the catalytic properties of acetylcholinesterase (AChE) and DNAzyme, the fluorescence signal is amplified for OPs detection. The method shows low detection limits and holds great potential for application in agricultural products.
Article
Chemistry, Analytical
Liya Zhou, Xitong Zhou, Congli Zhao, Yihang Liu, Yaoxuan Li, Li Ma, Ying He, Yanjun Jiang, Jing Gao
Summary: Mo2C/NCS, with excellent electron conduction channels and active sites, was used to fabricate AChE biosensors for OPs detection, showing wide linear ranges and outstanding detection limits.
MICROCHEMICAL JOURNAL
(2021)
Article
Environmental Sciences
Elenka Georgieva, Vesela Yancheva, Stela Stoyanova, Iliana Velcheva, Ilia Iliev, Tonka Vasileva, Veselin Bivolarski, Eleonora Petkova, Brigitta Laszlo, Krisztian Nyeste, Laszlo Antal
Summary: This study investigated the short-term negative effects of chlorpyrifos and cypermethrin on common carp under laboratory conditions. Results showed that both pesticides impacted the biomarkers in common carp even at concentrations lower than those permitted by law, with cypermethrin showing higher toxicity compared to chlorpyrifos. Caution should be exercised when using these pesticides to avoid any risk.