Article
Biochemistry & Molecular Biology
Lesia Savchenko, Ilenia Martinelli, Dimitri Marsal, Oksana Batkivska, Vyacheslav Zhdan, Igor Kaidashev, Nathalie Pizzinat, Frederic Boal, Helene Tronchere, Junwu Tao, Oksana Kunduzova
Summary: Environmental stress can disrupt the cardiovascular system and trigger various cell responses. This study investigated the effects of 915 MHz electromagnetic field (EMF) exposure on cardiac profiles in mice. The results showed that the cardiac antioxidant, metabolic, apoptotic, and fibro-inflammatory markers remained stable under EMF exposure.
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
(2023)
Article
Environmental Sciences
Masoud Khosravipour, Masoud Ghanbari Kakavandi, Faramarz Gharagozlou, Farshad Nadri, Akbar Barzegar, Khosro Emami, Hossein Valadi Athar
Summary: A four-year repeated measures study was conducted to quantify the long-term effects of noise, extremely low-frequency electromagnetic fields (ELF-EMFs), and shift work on liver enzymes. The study found that an increase in noise and ELF-EMFs was significantly associated with changes in liver enzymes. Shift work, especially 3-rotating night shifts, also had a significant impact on liver enzymes. Furthermore, significant interaction effects were observed among noise, ELF-EMFs, and shift work.
ENVIRONMENTAL POLLUTION
(2023)
Article
Plant Sciences
Saeed R. H. A. Al Shamsi, Gabriel A. Rabert, Shyam S. Kurup, Mohammed Abdul Muhsen Alyafei, Abdul Jaleel
Summary: This study investigated the biochemical changes and antioxidant variations in the leaves of different date palm varieties in the UAE, revealing significant differences in protein, phenol, ascorbic acid, glutathione, and alpha-tocopherol contents, as well as peroxidase and polyphenol oxidase activity. The variations in antioxidant enzyme activity and content suggest potential roles in flower development regulation.
Review
Food Science & Technology
Mohammad Yassin Zamanian, Mehraveh Sadeghi Ivraghi, Lusine G. Khachatryan, Diana E. Vadiyan, Hanie Yavarpour Bali, Maryam Golmohammadi
Summary: Non-alcoholic fatty liver disease (NAFLD) is often associated with metabolic disorders and is prevalent in obese and diabetic patients. Pomegranate polyphenols have antioxidant capabilities that can help reduce oxidative stress and inflammation associated with NAFLD. Therefore, research has found that pomegranate can attenuate oxidative stress, inflammation, and other risk factors associated with NAFLD, ultimately preventing the disease's development.
FOOD SCIENCE & NUTRITION
(2023)
Article
Food Science & Technology
Paulina Leite, Isabel Belo, Jose Manuel Salgado
Summary: Agro-industrial by-products are increasingly valuable as a source of antioxidant compounds. Enzymatic extraction techniques show promise in releasing bioactive compounds with reduced environmental impact. Solid-state fermentation was used to produce a crude enzymatic extract from olive pomace and brewery spent-grain, which showed stability and effectiveness in extracting antioxidant compounds from winery, olive mill, and brewery by-products.
Article
Multidisciplinary Sciences
Mariam Salameh, Sukaina Zeitoun-Ghandour, Lina Sabra, Ahmad Daher, Mahmoud Khalil, Wissam H. Joumaa
Summary: This study investigated the effects of continuous 24-hour exposure to mobile communication electromagnetic fields on oxidative stress, apoptosis, and inflammation in the liver of rat fetuses. The results showed that exposure to electromagnetic radiation increased oxidative stress, apoptosis, and inflammation, but before a sensitive developmental stage, the mother may provide protection for the embryos.
SCIENTIFIC REPORTS
(2023)
Article
Plant Sciences
Tian-liang Chang, Qian-qian Xi, Xiang-yu Wei, Li Xu, Qian-qian Wang, Jia-yi Fu, Chen Ling, Yue Zuo, Yi Zhao, Hong-yan He, Yu-wei Zhao
Summary: Melatonin can help plants maintain stable redox homeostasis under cold stress, which has a positive impact on plant stress resistance.
ENVIRONMENTAL AND EXPERIMENTAL BOTANY
(2022)
Article
Materials Science, Multidisciplinary
Zhenfei Li, Ji Liu, Jin Zhang, Linda Shao, Chiben Zhang, Xiong Wang, Ronghong Jin, Weiren Zhu
Summary: A method for highly efficient wavefront manipulation with irregular shaped metasurfaces is proposed in this paper. The method establishes a universal iterative modulation relation between the metasurface and scattered field by introducing boundary constraints at the aperture, enabling to deal with the electromagnetic scattering from a metasurface with arbitrary spatial shape.
ADVANCED MATERIALS TECHNOLOGIES
(2022)
Article
Biotechnology & Applied Microbiology
Jerome Ndudi Asiwe, Tolunigba Abisola Kolawole, Kenneth Kelechi Anachuna, Emmanuel Ikemefuna Ebuwa, Bartholomew Chukwuebuka Nwaogueze, Harrison Eruotor, Vincent Igbokwe
Summary: The study found that cabbage juice can significantly alleviate lead-induced liver and kidney dysfunction by reducing serum concentrations of urea, creatinine, ALP, AST, and ALT. Antioxidants (SOD, CAT, GSH) in liver and kidney tissues were also upregulated. Cabbage juice restored the tissue architecture changes caused by lead intoxication.
Article
Environmental Sciences
Piotr Piszczek, Karolina Wojcik-Piotrowicz, Krzysztof Gil, Jolanta Kaszuba-Zwoinska
Summary: The positive or negative impact of electromagnetic fields (EMF) on living organisms is still a debated topic as results remain inconsistent. The immune system, consisting of various cell types, plays a crucial role in defending the organism against external stressors. Factors that affect immunomodulatory effects can influence the immune response.
ENVIRONMENTAL RESEARCH
(2021)
Article
Agricultural Engineering
Paulina Leite, Isabel Belo, Jose Manuel Salgado
Summary: The co-processing of wastes from different agro-food industries through solid-state fermentation can produce lignocellulolytic enzymes and antioxidant compounds, achieving the valorization of these wastes. The fermentation of waste mixtures resulted in high enzymatic and antioxidant activities, allowing for the co-management of agro-industrial wastes.
INDUSTRIAL CROPS AND PRODUCTS
(2021)
Review
Medicine, General & Internal
Maria Jesus Vinolo-Gil, Manuel Rodriguez-Huguet, Cristina Garcia-Munoz, Gloria Gonzalez-Medina, Francisco Javier Martin-Vega, Rocio Martin-Valero
Summary: Electromagnetic fields have shown positive effects in treating spasticity, both when applied to the brain and peripheral areas. A systematic review of 10 clinical trials found that 80% of the studies reported improvements in various spasticity-related measures. However, caution should be exercised due to the heterogeneity of the studies and the limited number of articles. Future research should aim to establish standardized parameters and assessment methods to enhance the objectivity of studying the effectiveness of electromagnetic fields in treating spasticity.
JOURNAL OF CLINICAL MEDICINE
(2022)
Article
Materials Science, Multidisciplinary
Ivan Fernandez-Corbaton
Summary: The electromagnetic helicity of the free electromagnetic field and the static magnetic helicity are revealed to be two different manifestations of the same physical quantity, the total helicity. The total helicity is a combination of two terms measuring different aspects of helicity in different frequency regimes, establishing a theoretical basis for studying the interconversion between these two forms of total helicity in light-matter interactions.
Article
Biochemistry & Molecular Biology
Lukasz Swiatek, Elwira Sieniawska, Kouadio Ibrahime Sinan, Magdalena Maciejewska-Turska, Anastazja Boguszewska, Malgorzata Polz-Dacewicz, Ismail Senkardes, Gokalp Ozmen Guler, Nabeelah Bibi Sadeer, Mohamad Fawzi Mahomoodally, Gokhan Zengin
Summary: This study focused on the biological evaluation and chemical characterization of Geranium pyrenaicum Burm. f. Different solvent extracts were prepared and investigated for phytochemical profile, antioxidant, enzyme inhibitory activity, and cytotoxicity. Liquid chromatography-electrospray ionization-quadrupole time-of-flight-mass spectrometry allowed to identify a total of 56 compounds in the extracts. The study showed that the aqueous extract possessed the highest antioxidant capacity and selectivity towards cancer cell lines, while the ethyl acetate and methanolic extracts exhibited significant enzyme inhibitory activities. The presence of bioactive antiviral molecules in the extracts may be related to the high anti HSV-1 activity of the methanolic extract.
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
(2021)
Article
Chemistry, Physical
Vladimir Y. Chernyak, Shaul Mukamel
Summary: This discussion focuses on the Heisenberg uncertainty relation for spatially-gated electric and magnetic field fluctuations, highlighting the need to consider the quantum nature of the electromagnetic field in confined spaces. Optimizing the state of light allows for trade-offs between Delta E and Delta H, and spatial confinements and quantum fields can alternatively be achieved through the interaction of light with nanostructures. Potential applications include nonlinear spectroscopy of nanostructures and optical cavities, as well as chiral signals.
JOURNAL OF CHEMICAL PHYSICS
(2021)
Article
Environmental Sciences
Mohamed Amr El-Missiry, Sameh Shabana, Sara J. Ghazala, Azza I. Othman, Maggie E. Amer
Summary: The study demonstrated that melatonin has potential neuroprotective properties in reducing inflammation, oxidative stress, and apoptosis in the brains of rats exposed to gamma radiation. This suggests that melatonin may have beneficial effects in clinical and occupational settings involving radiation exposure. Further research is needed to fully understand its neuroprotective effects in humans.
ENVIRONMENTAL SCIENCE AND POLLUTION RESEARCH
(2021)
Article
Instruments & Instrumentation
Radwa H. Abou-Saleh, Fern J. Armistead, Damien V. B. Batchelor, Benjamin R. G. Johnson, Sally A. Peyman, Stephen D. Evans
Summary: This paper presents a new instrument called Horizon for producing microbubbles, which is robust, portable, and user-friendly, capable of producing microbubbles with specific properties including monodisperse microbubbles, more disperse but higher yield microbubbles, nanobubbles, and therapeutic microbubbles with drug payloads. Multiplexed chips can improve production rates up to 16-fold while maintaining production stability. This work suggests that Horizon is a versatile instrument with potential for mass production and widespread use in research facilities to bridge the gap between therapeutic microbubble research and clinical applications.
REVIEW OF SCIENTIFIC INSTRUMENTS
(2021)
Article
Multidisciplinary Sciences
Omar A. Ammar, Mohamed A. El-Missiry, Azza I. Othman, Maggie E. Amer
Summary: This study investigated the antitumor molecular mechanisms of melatonin on HepG2 cells, and found that melatonin inhibits proliferation and angiogenesis, induces apoptosis and oxidative stress.
Article
Environmental Sciences
Mohamed E. Abdraboh, Mohamed A. El-Missiry, Azza Othman, Ahmed Nageeb Taha, Dalia S. Abd Elhamed, Maggie E. Amer
Summary: Exposure to light at night, pineal gland impairment, and TCE pollution have a significant impact on health, including increased susceptibility to liver toxicity and cancer. Low melatonin levels, constant light exposure, and the combination of these factors increase the toxic and carcinogenic effects of TCE on the liver.
ENVIRONMENTAL SCIENCE AND POLLUTION RESEARCH
(2022)
Article
Biochemistry & Molecular Biology
Maggie E. Amer, Maher A. Amer, Azza Othman, Doaa A. Elsayed, Mohamed Amr El-Missiry, Omar A. Ammar
Summary: This study investigated the anti-tumor role of silymarin and its molecular targets in Ehrlich solid tumor xenografts in vivo. The results showed that silymarin inhibited tumor growth through activating apoptosis, inhibiting cell division, and reducing angiogenesis. Silymarin also showed potential ability to inhibit metastasis.
MOLECULAR BIOLOGY REPORTS
(2022)
Article
Environmental Sciences
Maher A. Amer, Azza Othman, Mohamed A. El-Missiry, Aya A. Farag, Maggie E. Amer
Summary: The study found that PAs have an anti-fibrotic effect on CCl4-induced liver injury and fibrosis by modulating the interdependence of oxidative stress, inflammation, apoptosis, and DNA integrity.
ENVIRONMENTAL SCIENCE AND POLLUTION RESEARCH
(2022)
Article
Cell Biology
Haitham L. Abdulhadi, Banan R. Dabdoub, Loay H. Ali, Azza Othman, Maggie E. Amer, Mohamed A. El-Missiry
Summary: Punicalagin has protective effects against pancreatic inflammation and oxidative damage in T1DM, reducing inflammatory and adhesion molecule levels, enhancing antioxidant capacity, and improving pancreatic histopathology and immune response in diabetic rats.
MOLECULAR AND CELLULAR BIOCHEMISTRY
(2022)
Article
Neurosciences
Mostafa D. Mostafa, Magda A. ElKomy, Azza Othman, Maggie E. Amer, Mohamed A. El-Missiry
Summary: Epigallocatechin-3-gallate (EGCG) has been shown to protect against brain damage and cognitive dysfunction, reducing homocysteine levels and the formation of amyloid-beta and tau protein. Additionally, EGCG improves cognitive and memory impairment in hyperhomocysteinemia-induced mice by modulating glutamate and gamma-aminobutyric acid levels in the brain.
NEUROTOXICITY RESEARCH
(2022)
Article
Biochemistry & Molecular Biology
Afraa S. H. Alobaidy, Mona Elhelaly, Maggie E. Amer, Rasha S. Shemies, Azza I. Othman, Mohamed A. El-Missiry
Summary: The study aimed to evaluate the association between oxidative stress and ACE2 expression with the clinical severity of COVID-19. The results showed that COVID-19 patients had lower ACE2 expression and higher oxidative stress levels compared to the control group. Melatonin supplementation may serve as an adjunct therapy to reduce disease severity and mortality in COVID-19 patients.
MOLECULAR BIOLOGY REPORTS
(2023)
Article
Zoology
Mona E. Elbanan, Maggie E. Amer, Mohamed A. El-Missiry, Azza I. Othman, Sameh M. Shabana
Summary: The study shows that melatonin (MLT) has a protective effect against 5-fluorouracil (5-FU)-induced kidney injury by reducing inflammation, apoptosis, and lipid peroxidation. It also improves renal function and preserves histological structure.
JOURNAL OF EXPERIMENTAL ZOOLOGY PART A-ECOLOGICAL AND INTEGRATIVE PHYSIOLOGY
(2023)
Correction
Biology
Maggie E. Amer, Azza I. Othman, Hajer Mohammed Abozaid, Mohamed A. El-Missiry
BIOLOGICAL RESEARCH
(2023)
Article
Oncology
Sameh M. Shabana, Nahla S. Gad, Azza I. Othman, Aly Fahmy Mohamed, Mohamed Amr El-Missiry
Summary: Research is being conducted to test the chemopreventive properties of natural dietary substance beta-caryophyllene oxide (CPO) against lung cancer. CPO inhibits proliferation of lung cancer cells and induces cell cycle arrest and apoptosis, which could be a potential therapeutic target for lung cancer treatment.
Article
Biology
Maggie E. Amer, Azza Othman, Hajer Mohammed Abozaid, Mohamed A. El-Missiry
Summary: This study demonstrates that melatonin (MLT) mitigates radiation-induced testicular injury through its antioxidant, anti-inflammatory, anti-apoptotic, and anti-DNA damage actions.
BIOLOGICAL RESEARCH
(2022)
Article
Chemistry, Multidisciplinary
Samar A. Salim, Elbadawy A. Kamoun, Stephen Evans, Tarek H. Taha, Esmail M. El-Fakharany, Mohamed M. Elmazar, A. F. Abdel-Aziz, R. H. Abou-Saleh, Taher A. Salaheldin
Summary: The study successfully synthesized PVP-hydrogen peroxide complex and incorporated it into PMMA nanofibrous scaffold. The optimized ratio of 1:1.5 PHP complex exhibited ideal oxygen release effects and high selectivity for cancer cells, especially breast cancer cells. The PMMA-10% PHP nanofibers showed the highest concentration of released-oxygen and potential for enhancing cancer treatment effects.
Article
Multidisciplinary Sciences
Doaa A. Abdulwahab, Mohamed A. El-Missiry, Sameh Shabana, Azza I. Othman, Maggie E. Amer
Summary: The research found that MLT has anti-hyperglycemic, lipid-lowering, and antioxidant effects on diabetic rats, preventing oxidative stress and protecting the heart and pancreas. It also shows remarkable anti-inflammatory and anti-apoptotic properties.
