Article
Medicine, Research & Experimental
Daniel Blumenthal, James A. A. Leonard, Andy Habib, Hengameh Behzadpour, Alexandra Espinel, Diego Preciado
Summary: There has been a notable increase in the number of extremely premature neonates requiring tracheostomy and laryngotracheal reconstruction (LTR). This study aimed to compare the outcomes of LTR in extremely premature infants to those born preterm and term, focusing on decannulation rates, time to decannulation, and complication rates.
Article
Pediatrics
Julianne R. McGlynn, Brianna C. Aoyama, Joseph M. Collaco, Sharon A. McGrath-Morrow
Summary: This study found that children with BPD and FHA were more likely to have respiratory symptoms and increased acute care usage during the first 3 years of life, and that FHA was associated with lower socioeconomic status. There was no association between FHA and BPD severity.
PEDIATRIC PULMONOLOGY
(2021)
Article
Pediatrics
Nianzhou Xiao, Michelle Starr, Adrienne Stolfi, Gilad Hamdani, Shireen Hashmat, Stefan G. Kiessling, Christina Sethna, Mahmoud Kallash, Robyn Matloff, Robert Woroniecki, Keia Sanderson, Ikuyo Yamaguchi, Stephen D. Cha, Michael G. Semanik, Rahul Chanchlani, Joseph T. Flynn, Mark Mitsnefes
Summary: This multicenter study reports that most infants diagnosed with idiopathic hypertension in the NICU will discontinue antihypertensive treatment within 2 years of discharge. Antenatal steroid treatment is associated with a decreased likelihood of needing antihypertensive therapy for more than 1 year.
JOURNAL OF PEDIATRICS
(2024)
Article
Pediatrics
Josephine Funck Bilsteen, Suvi Alenius, Magne Brathen, Klaus Borch, Claus Thorn Ekstrom, Eero Kajantie, Mariam Lashkariani, Markku Nurhonen, Kari Risnes, Sven Sandin, Kjetil A. van der Wel, Dieter Wolke, Anne-Marie Nybo Andersen
Summary: Preterm birth has negative effects on educational attainment in adults, and parental education level does not mitigate these effects.
Article
Pediatrics
Vineet Lamba, Oscar Winners, Prem Fort
Summary: The study found that early high-dose caffeine (HD) therapy can reduce the duration of mechanical ventilation in premature infants and decrease the risk of bronchopulmonary dysplasia (BPD).
Article
Psychology, Multidisciplinary
Sam Clingan-Siverly, Paige M. Nelson, Tilbe Goksun, O. Ece Demir-Lira
Summary: Spatial skills play an important role in predicting children's academic achievements, and their performance can be influenced by the spatial language and gestures they are exposed to. While term and preterm-born children did not differ significantly in their performance on mental transformation and block design tasks, the variability within each group suggests that individual differences may play a role. Parental spatial language and gestures indirectly impact children's spatial performance through children's own use of spatial language and gestures.
FRONTIERS IN PSYCHOLOGY
(2021)
Article
Psychology, Clinical
Sigal Zilcha-Mano, Yaara Shimshoni, Wendy K. Silverman, Eli R. Lebowitz
Summary: Parent-child agreement on family accommodation may predict subsequent treatment outcome, with potentially different effects for different treatments (SPACE vs. CBT). Multiple-informant assessment of accommodation provides valuable information for treatment personalization.
JOURNAL OF CLINICAL CHILD AND ADOLESCENT PSYCHOLOGY
(2021)
Article
Pediatrics
Morgan E. Hill, Ashley Martin, Sara B. DeMauro
Summary: This study aims to describe the barriers and facilitators to reading to preterm-born infants, both in the NICU and at home, as reported by parents. The study identifies common barriers and facilitators to reading in both the NICU and home environment.
ACADEMIC PEDIATRICS
(2022)
Article
Pediatrics
Hannah Brophy, Gaik Min Tan, Charles William Yoxall
Summary: Admission hyperthermia is independently associated with an increased risk of preterm brain injury, but causality cannot be determined.
Article
Medicine, General & Internal
Vivek V. Shukla, J. Paige Souder, Grant Imbrock, Muhan Hu, A. K. M. Fazlur Rahman, Colm P. Travers, Namasivayam Ambalavanan, Waldemar A. Carlo, Charitharth Vivek Lal
Summary: The findings of this cohort study suggest that noninvasive respiratory support in the first 10 minutes after birth is feasible but does not decrease the risk of bronchopulmonary dysplasia (BPD) or death compared to intubation and early surfactant delivery in nano-preterm infants.
Article
Medicine, General & Internal
Can Liu, Alessandra Grotta, Ayako Hiyoshi, Lisa Berg, Mikael Rostila
Summary: This sibling cohort study conducted in Sweden aims to examine the impact of parental death on school outcomes and found that parental death is associated with poorer school grades and a higher risk of being ineligible for upper secondary education.
Article
Biochemistry & Molecular Biology
J. Ameixa, E. Arthur-Baidoo, J. Pereira-da-Silva, M. Oncak, J. C. Ruivo, M. T. do N. Varella, F. Ferreira da Silva, S. Denifl
Summary: We report electron attachment (EA) measurements and quantum chemical calculations for Coenzyme Q0 (CoQ0), which is a prototype for electron withdrawing CoQn molecules. The mechanisms for the parent anion radical formation in CoQ0 and CoQn (n = 1,2,4) are remarkably distinct. The isoprenoid side chains in CoQn molecules seem to influence the formation of dipole bound states (DBS), while for CoQ0, the parent anion radical is unstable at lower energies due to its short auto-ionization lifetimes.
COMPUTATIONAL AND STRUCTURAL BIOTECHNOLOGY JOURNAL
(2023)
Review
Pediatrics
Laure Boissel, Jean-Marc Guile, Sylvie Viaux-Savelon, Charlotte Mariana, Pascal Corde, Fabrice Wallois, Xavier Benarous
Summary: Book-reading interventions have been found to have positive effects on language development in full-term infants. This review explores the theoretical evidence, empirical findings, and practical challenges of introducing these interventions to preterm infants. The interventions have been shown to have positive effects on linguistic input, interactive communication, and parental stress reduction. Parental shared book reading in a neonatal intensive care unit (NICU) has been proven feasible and accepted, providing support for positive parenting in a stressful environment. Preliminary evidence suggests that shared reading sessions in NICU have positive effects on physiological parameters and language development in preterm infants, with long-term studies confirming positive effects on cognitive development. However, further research is needed to confirm these findings and study possible moderators, such as cultural factors.
FRONTIERS IN PEDIATRICS
(2022)
Article
Environmental Sciences
Chalana M. Sol, Charissa Van Zwol-Janssens, Elise M. Philips, Alexandros G. Asimakopoulos, Maria-Pilar Martinez-Moral, Kurunthachalam Kannan, Vincent W. V. Jaddoe, Leonardo Trasande, Susana Santos
Summary: Higher maternal bisphenol S urine concentrations, especially in the first trimester, seem to be associated with larger fetal head circumference, higher weight, and a lower risk of being small size for gestational age at birth. Other bisphenols were not consistently associated with fetal growth outcomes.
ENVIRONMENTAL HEALTH
(2021)
Article
Neurosciences
Roksana Malak, Katarzyna Wiechec, Brittany Fechner, Tomasz Szczapa, Joanna Kasperkowicz, Maja Matthews-Kozanecka, Teresa Matthews Brzozowska, Oskar Komisarek, Wlodzimierz Samborski, Ewa Mojs
Summary: The study found that neurobehavior directly impacts the sucking reflex and eating abilities of very preterm neonates. Therefore, close assessment of neurobehavior in these neonates is crucial for early intervention and rehabilitation planning to address fundamental issues and facilitate feeding skills.
Article
Psychology, Clinical
Courtney P. Gilchrist, Deanne K. Thompson, Bonnie Alexander, Claire E. Kelly, Karli Treyvaud, Lillian G. Matthews, Leona Pascoe, Diana Zannino, Rosemary Yates, Chris Adamson, Mary Tolcos, Jeanie L. Y. Cheong, Terrie E. Inder, Lex W. Doyle, Angela Cumberland, Peter J. Anderson
Summary: This study aimed to compare the developmental trajectories of corticolimbic regions in very preterm (VP) children with and without anxiety diagnosis at 13 years. The results showed that VP children with anxiety disorders displayed altered trajectories in whole brain and specific regions compared to VP children without anxiety. These alterations mainly reflected slower growth in early childhood and did not persist after adjusting for total brain volume and social risk.
PSYCHOLOGICAL MEDICINE
(2023)
Review
Pediatrics
Rachel Robinson, Polina Girchenko, Anna Pulakka, Kati Heinonen, Anna Lahdepuro, Marius Lahti-Pulkkinen, Petteri Hovi, Marjaana Tikanmaki, Peter Bartmann, Aulikki Lano, Lex W. Doyle, Peter J. Anderson, Jeanie L. Y. Cheong, Brian A. Darlow, Lianne J. Woodward, L. John Horwood, Marit S. Indredavik, Kari Anne Evensen, Neil Marlow, Samantha Johnson, Marina Goulart de Mendonca, Eero Kajantie, Dieter Wolke, Katri Raikkonen
Summary: This study examined the differences in ADHD symptoms and diagnosis between preterm and term-born adults and found that while preterm adults may not report higher levels of ADHD symptoms, they have a higher risk of receiving an ADHD diagnosis in adulthood.
PEDIATRIC RESEARCH
(2023)
Article
Rehabilitation
Kate L. Cameron, Cassie E. McDonald, Kim Allison, Jennifer L. McGinley, Jeanie L. Cheong, Alicia J. Spittle
Summary: This study explores the acceptability of a dance participation intervention for extremely preterm children at preschool age. The findings indicate that Dance PREEMIE is acceptable to both parents and dance teachers. These findings can inform future interventions aiming to improve physical activity participation for children with motor impairment at preschool age.
PHYSIOTHERAPY THEORY AND PRACTICE
(2023)
Article
Respiratory System
Lex William Doyle, Sarath Ranganathan, Jeanie Cheong
Summary: The study investigates the independent associations between bronchopulmonary dysplasia (BPD) and reduced expiratory airflow in children born extremely preterm. The results show that moderate-severe BPD, but not mild BPD, is independently associated with reduced expiratory airflow at 8 years of age. Other factors like gestational age and birth weight z-score were not found to be associated with expiratory airflow.
Article
Health Care Sciences & Services
Corneliu Bolbocean, Peter J. Anderson, Peter Bartmann, Jeanie L. Y. Cheong, Lex W. Doyle, Dieter Wolke, Stavros Petrou
Summary: This study examined the agreement between two different instruments used to measure health-related quality of life in individuals born very preterm and/or with low birthweight. The study found that the HUI3 tool captured preterm-related changes in health status more accurately, while the SF-6D tool was more accurate in measuring the health status of the control group.
QUALITY OF LIFE RESEARCH
(2023)
Review
Psychology, Educational
Garance Delagneau, E. Sabrina Twilhaar, Renee Testa, Sarit van Veen, Peter Anderson
Summary: This meta-analysis examined the relationship between prenatal maternal stress and/or anxiety and the outcomes of children aged 3 months to 9 years. Of the 8754 studies published before June 2021 that were synthesized, 17 conducted in Western countries were included in the meta-analysis (N-total = 23,307; M-males 54%; M-ethnicity White 77%, Pacific 15%, African American/Black 10%, Middle Eastern 7%, Eastern 8%). Effect sizes ranged from -0.41 to 0.15. A weak negative association was found between prenatal stress and/or anxiety exposure and children's general intellectual development. Associations varied based on the type of exposure. Findings are limited to developed counties and cannot be generalized to low- and middle-income countries. Directions for maternal prenatal intervention and future studies are discussed.
Article
Pediatrics
Megan Spencer-Smith, Amber Weinman, Jon Quach, Leona Pascoe, Fiona Mensah, Melissa Wake, Gehan Roberts, Peter J. Anderson
Article
Pediatrics
Rocco Cuzzilla, Frances M. Cowan, Sheryle Rogerson, Peter J. Anderson, Lex W. Doyle, Jeanie Ling Yoong Cheong, Alicia Spittle
Summary: This study aimed to explore the relationship between early postnatal cranial ultrasound (cUS) linear measures of brain size and brain growth and neurodevelopment at 2 years in infants born <30 weeks' gestational age (GA). The results showed that larger measures of brain tissue and fluid spaces within the first weeks after birth were related to better cognitive and language development at 2 years. However, further research is needed to investigate the relationship between early cUS linear measures and fluid spaces and later neurodevelopment.
ARCHIVES OF DISEASE IN CHILDHOOD-FETAL AND NEONATAL EDITION
(2023)
Article
Clinical Neurology
Emilyn Soon, Vanessa Siffredi, Peter J. Anderson, Vicki A. Anderson, Alissandra McIlroy, Richard J. Leventer, Amanda G. Wood, Megan M. Spencer-Smith
Summary: This study examined the differences in interference control and response inhibition between children with AgCC and typically developing children. It also explored the impact of different anatomical features of AgCC on these abilities. The results showed that children with AgCC had poorer performance in inhibitory control measures compared to TD children, and those with a complex AgCC had worse response inhibition performance than those with isolated AgCC. The study also found that the volume and microstructure of the anterior and posterior commissures may compensate for the absence of the corpus callosum, contributing to better inhibitory control outcomes.
JOURNAL OF THE INTERNATIONAL NEUROPSYCHOLOGICAL SOCIETY
(2023)
Review
Behavioral Sciences
Claire E. Kelly, Michelle Shaul, Deanne K. Thompson, Rheanna M. Mainzer, Joseph Y. M. Yang, Thijs Dhollander, Jeanie L. Y. Cheong, Terrie E. Inder, Lex W. Doyle, Peter J. Anderson
Summary: Early life experiences, such as very preterm birth, can have long-term effects on brain and cognitive development. This study synthesized previous research on brain structure in adults born very preterm (VP) and found volumetric, morphologic, and microstructural alterations in specific regions of the brain compared to controls. These findings suggest a persisting neurological impact of VP birth, which may provide insights into the development of cognition in high-risk populations.
NEUROSCIENCE AND BIOBEHAVIORAL REVIEWS
(2023)
Article
Medicine, General & Internal
Karen P. Best, Jacqueline F. Gould, Maria Makrides, Thomas Sullivan, Jeanie Cheong, Shao J. Zhou, Stefan Kane, Huda Safa, A. Sparks, Lex W. Doyle, A. J. McPhee, Tanya A. C. Nippita, Hossein H. A. Afzali, Rosalie Grivell, D. Mackerras, E. Knight, Simon Wood, Tim Green
Summary: This study aims to determine the effect of reducing iodine intake from supplements on the cognitive development of children at 24 months of age. A total of 754 pregnant women will be randomly assigned to receive either a low iodine or a common dose of iodine supplement. The primary outcome is the developmental quotient of infants at 24 months of age.
Article
Health Care Sciences & Services
Jing Wang, Yanhong Jessika Hu, Lana Collins, Anna Fedyukova, Varnika Aggarwal, Fiona Mensah, Jeanie L. Y. Cheong, Melissa Wake
Summary: This study aims to establish a proof-of-concept of a Victoria-wide registry of babies admitted to special care nurseries (SCN) in the GenV cohort. The registry will include a minimum dataset harmonized with the Australian and New Zealand Neonatal Network (ANZNN) and will serve as a resource for longitudinal research through its integration with the GenV cohort and linked datasets.
INTERNATIONAL JOURNAL OF POPULATION DATA SCIENCE (IJPDS)
(2023)
Article
Health Care Sciences & Services
Jeanie L. Y. Cheong, Joy E. Olsen, Tayla Konstan, Rheanna M. Mainzer, Leah M. Hickey, Alicia J. Spittle, John D. Wark, Michael M. Cheung, Suzanne M. Garland, Julianne Duff, Marissa Clark, Penelope Stevens, Lex W. Doyle
Summary: This study tracked the growth of children born extremely preterm (EP, <28 weeks' gestation) beyond late adolescence and found that the gap in weight and BMI between EP and term-born controls decreased with age. Greater increases in BMI were associated with poorer cardiometabolic health, and the association between being overweight and poorer cardiometabolic health strengthened with age. The catch-up growth in weight and BMI in survivors born EP may not be desirable, and being overweight from mid-childhood may provide a window for intervention.
LANCET REGIONAL HEALTH-WESTERN PACIFIC
(2023)
Article
Health Care Sciences & Services
Regine Cassandra Lau, Peter John Anderson, Joshua F. Wiley, Derek Huang, Faisha Surjatin, Paul Mcintosh, Susan Gathercole, Megan Spencer-Smith
Summary: This study aims to test the effects of working memory training on cognitive improvement in children, using different methods of difficulty setting and comparing with an active control group. The study uses experimental interventions and various assessment measures, providing valuable information for future research and design of cognitive training interventions.
JMIR RESEARCH PROTOCOLS
(2023)
Article
Medicine, General & Internal
Lex W. Doyle, S. Ranganathan, A. J. Spittle, G. Opie, R. M. Mainzer, Jeanie L. Y. Cheong
Summary: This study aimed to describe the changes in expiratory airflow at 7-8 years of age in survivors born extremely low birth weight (ELBW) before and after the introduction of exogenous surfactant. The results showed that there was no improvement in expiratory airflow in ELBW children with the introduction of surfactant, and there may be a deterioration in those with bronchopulmonary dysplasia (BPD).