Journal
JOURNAL OF PHYSICAL CHEMISTRY B
Volume 119, Issue 44, Pages 13964-13970Publisher
AMER CHEMICAL SOC
DOI: 10.1021/acs.jpcb.5b07494
Keywords
-
Categories
Funding
- Deutsche Forschungsgemeinschaft [GRK1640]
- State of Bavaria within the initiative Solar Technologies go Hybrid
- BBSRC
- Biotechnology and Biological Sciences Research Council [BB/G003831/1] Funding Source: researchfish
- BBSRC [BB/G003831/1] Funding Source: UKRI
Ask authors/readers for more resources
Proteins are supramolecular machines that carry out a wide range of different functions, many of which require flexibility. Up until now spontaneous conformational fluctuations of proteins have always been assumed to reflect a stochastic random process. However, if changing between different conformational states was random, then it would be difficult to understand how conformational control of protein function could have evolved. Here we demonstrate that a single protein can show conformational memory. This is exactly the process that can facilitate the evolution of control of switching between two conformational states that can then be used to regulate protein function.
Authors
I am an author on this paper
Click your name to claim this paper and add it to your profile.
Reviews
Recommended
No Data Available