Article
Otorhinolaryngology
Howell Henrian G. Bayona, Nicole Pizzorni, Jan Tack, Ann Goeleven, Taher Omari, Nathalie Rommel
Summary: This study demonstrates the diagnostic value of certain proposed and adjunct HRPM metrics for identifying signs of unsafe and inefficient bolus transport in patients with oropharyngeal dysphagia.
Article
Audiology & Speech-Language Pathology
Niall Heslin, Julie Regan
Summary: This study found that effortful swallowing significantly affects the pharyngeal swallowing biomechanics in adults with dysphagia, including an increase in pharyngeal contractile and opening duration. This suggests that effortful swallowing can improve swallowing difficulties and warrants further investigation in larger clinical populations.
INTERNATIONAL JOURNAL OF SPEECH-LANGUAGE PATHOLOGY
(2022)
Article
Otorhinolaryngology
Kenjiro Kunieda, Ichiro Fujishima, Hidetaka Wakabayashi, Tomohisa Ohno, Takashi Shigematsu, Masataka Itoda, Fumiko Oshima, Takashi Mori, Nami Ogawa, Sumito Ogawa
Summary: This study aimed to assess the relationship between tongue pressure and swallowing function, and found that dysphagia patients with sarcopenia have weaker pharyngeal contractility and UES dysfunction. However, there was no significant correlation between HRM parameters and tongue pressure as well as sarcopenia-related factors. Further research is needed to clinically apply tongue pressure in evaluating sarcopenic dysphagia.
Article
Medicine, General & Internal
Chul-Hyun Park, Kunwoo Kim, Jin-Tae Hwang, Jae-Hyung Choi, Yong-Taek Lee, Young Sook Park, Jung Ho Park, Kyung Jae Yoon
Summary: This study compared two methods of measuring upper esophageal sphincter (UES) relaxation and determined their diagnostic value in UES relaxation impairment. The results showed that VFSS and HRM have complementary ability in evaluating UES relaxation duration in patients with oropharyngeal dysphagia.
Article
Otorhinolaryngology
Jodi Hernandez, Glen Leverson, Susan Thibeault
Summary: The study found that patients prefer atomized lidocaine for increased comfort during pharyngeal high-resolution manometry procedures. While no significant differences were detected in pharyngeal pressure measurements between the two groups, the use of atomized lidocaine did not affect measurement outcomes.
Article
Otorhinolaryngology
Sophia M. Colevas, Lily N. Stalter, Corinne A. Jones, Timothy M. McCulloch
Summary: This study investigated factors influencing self-selected swallow volume and found that age, gender, and pharyngeal hold area were significantly associated with an increase in self-selected bolus volume. Self-selected swallows showed differences in swallowing pressures and timing events compared to predetermined volume swallows.
Article
Otorhinolaryngology
Nicole E. Schaen-Heacock, Corinne A. Jones, Timothy M. McCulloch
Summary: Measuring pharyngeal swallowing pressures in patients with radiation-associated dysphagia using HRM can help clinicians form more precise treatment plans, as these patients exhibit alterations in swallowing pressure.
Review
Otorhinolaryngology
Eva Mary Diver, Julie Regan
Summary: This study explores the current use of pharyngeal high-resolution manometry (PHRM) as a dysphagia evaluation in adults with motor neurone disease (MND). The findings suggest that PHRM shows potential in evaluating the effects of dysphagia interventions but further research is needed due to limited literature and methodological differences.
Article
Medicine, General & Internal
Daniel L. Cohen, Anton Bermont, Vered Richter, Narjes Azzam, Haim Shirin, Ram Dickman, Amir Mari
Summary: The study found that integrated relaxation pressure (IRP) can distinguish between the reflux-predominant and dysphagia-predominant phenotypes in patients with absent contractility (AC). This may have important clinical implications, as procedures such as fundoplication may benefit patients with reflux and a low IRP, while procedures like peroral endoscopic myotomy (POEM) may benefit patients with dysphagia and a relatively high IRP.
JOURNAL OF CLINICAL MEDICINE
(2022)
Article
Otorhinolaryngology
Shumon Dhar, Nogah Nativ-Zeltzer, Omid B. Mehdizadeh, Apoorva T. Ramaswamy, Yuval Nachalon, Peter C. Belafsky
Summary: The results of this pilot study demonstrate that pyridostigmine acutely improves esophageal contractile vigor in patients suffering from dysphagia with esophageal dysmotility. Further investigation with larger sample size, longer follow-up, side effect profile, and patient-reported outcome measures is still needed to determine the clinical usefulness of pyridostigmine in specific disorders of esophageal motility.
Article
Otorhinolaryngology
D. Stone, E. C. Ward, H. Bogaardt, R. Heard, B. Martin-Harris, A. C. Smith, J. M. Elliott
Summary: Difficulty swallowing is commonly reported after whiplash injury, possibly due to changes in pharyngeal volume. This exploratory study found a high prevalence of self-reported dysphagia in patients over a year, with DHI scores significantly increasing between early and late stages. However, there was no significant relationship between dysphagia and recovery status or changes in pharyngeal volume. Further research is needed to understand the nature of dysphagia and its impact post-whiplash injury.
Article
Gastroenterology & Hepatology
Sawangpong Jandee, Kasemsak Jandee
Summary: This study evaluated the diagnostic yield of high-resolution manometry in Thai patients, finding the highest yield in dysphagia patients. However, the test was not as beneficial in detecting clinically relevant esophageal motor disorders in patients presenting with non-dysphagia symptoms.
JOURNAL OF NEUROGASTROENTEROLOGY AND MOTILITY
(2021)
Article
Gastroenterology & Hepatology
Taher Omari, Charles Cock, Peter Wu, Michal Marcin Szczesniak, Mistyka Schar, Jan Tack, Nathalie Rommel
Summary: This study aimed to establish a methodology for diagnosing oropharyngeal disorders using P-HRM-I. The results showed that UES relaxation pressure was the best indicator for differentiating patients from controls and diagnosing UES disorders. A diagnostic scheme was also devised to identify patients with UES disorder or propulsive disorder. Additionally, the study found that patients with pharyngeal pressurizations and evidence of reduced UES relaxation and/or distensibility had higher aspiration scores.
NEUROGASTROENTEROLOGY AND MOTILITY
(2023)
Article
Gastroenterology & Hepatology
Austin J. Scholp, Matthew R. Hoffman, Sarah P. Rosen, Suzan M. Abdelhalim, Corinne A. Jones, Jack J. Jiang, Timothy M. McCulloch
Summary: In this study, spectral arc length (SPARC) analysis was applied to distinguish control subjects from those with post-stroke dysphagia using pharyngeal high-resolution manometry (HRM) data. Significant differences in SPARC values were found in the velopharynx, tongue base, and hypopharynx between the two subject groups, while values for the upper esophageal sphincter (UES) were similar. This suggests that SPARC analysis may offer valuable insights into the pathophysiology of dysphagia beyond traditional pressure and duration measures.
NEUROGASTROENTEROLOGY AND MOTILITY
(2021)
Article
Medicine, Research & Experimental
Seh Ling Kwong, Ester G. Hernandez, Katharina Winiker, Kristin Gozdzikowska, Phoebe Macrae, Maggie-Lee Huckabee
Summary: This study examined the effect of topical nasal anesthetic (TNA) on swallowing and tolerability during high-resolution impedance manometry (HRIM) with a 4.2-mm catheter. The results showed that TNA did not improve comfort or significantly affect swallowing behavior during the procedure.