Article
Medicine, General & Internal
Chul-Hyun Park, Kunwoo Kim, Jin-Tae Hwang, Jae-Hyung Choi, Yong-Taek Lee, Young Sook Park, Jung Ho Park, Kyung Jae Yoon
Summary: This study compared two methods of measuring upper esophageal sphincter (UES) relaxation and determined their diagnostic value in UES relaxation impairment. The results showed that VFSS and HRM have complementary ability in evaluating UES relaxation duration in patients with oropharyngeal dysphagia.
Review
Otorhinolaryngology
Sebastian H. Doeltgen, Harsharan Kaur, Stephanie K. Daniels, Leila Mohammadi, Joanne Murray
Summary: The upper esophageal sphincter (UES) is crucial for safe swallowing, and there are various behavioral interventions available to improve UES opening. Different types of interventions have shown varying degrees of success in improving UES opening, with limited evidence base for their effectiveness.
Article
Otorhinolaryngology
Keiko Fukino, Masahiro Tsutsumi, Akimoto Nimura, Koh Miwa, Takashi Ono, Keiichi Akita
Summary: This study examined the connection between the palatopharyngeus and inferior constrictor, finding that the former interlaces with the cricopharyngeal part of the latter through dense connective tissues. This connection may play a role in directly affecting the upper esophageal sphincter and aiding in its opening.
EUROPEAN ARCHIVES OF OTO-RHINO-LARYNGOLOGY
(2021)
Article
Rehabilitation
Karen B. Ng, Richard D. Jones, Esther Guiu Hernandez, Phoebe Macrae, Maggie-Lee Huckabee
Summary: This study aimed to identify and characterize subgroups of stroke patients with clinical signs of dysphagia based on swallowing-related strength and skill impairments of the submental muscle group. The research found several subgroups within stroke patients in terms of swallowing function, while healthy and myopathic participants demonstrated predominantly homogeneous swallowing patterns. Skill assessment in swallowing may play a more predictive role in classification of swallowing function.
ARCHIVES OF PHYSICAL MEDICINE AND REHABILITATION
(2021)
Article
Rehabilitation
Nayeon Ko, Hyun Haeng Lee, Min Kyun Sohn, Deog Young Kim, Yong-Il Shin, Gyung-Jae Oh, Yang-Soo Lee, Min Cheol Joo, So Young Lee, Min-Keun Song, Junhee Han, Jeonghoon Ahn, Young-Hoon Lee, Won Hyuk Chang, Soo Mi Choi, Seon Kui Lee, Jongmin Lee, Yun-Hee Kim
Summary: The study identified that the incidence of dysphagia after ischemic stroke was 32.3%. Predictive factors for the presence of dysphagia included age, low BMI, premorbid disabilities, brainstem lesions, and NIHSS.
ARCHIVES OF PHYSICAL MEDICINE AND REHABILITATION
(2021)
Article
Otorhinolaryngology
Sophia M. Colevas, Lily N. Stalter, Corinne A. Jones, Timothy M. Mcculloch
Summary: This study describes the manometric representation of the resting upper esophageal sphincter (UES) using a clinically accessible method of measurement. The results demonstrate excellent within-subject reliability of the resting UES mean pressures and significant effects of age, number of sensors contained within the resting UES, and preceding swallow volume on mean resting UES pressure.
Article
Otorhinolaryngology
Katharina Winiker, Kristin Gozdzikowska, Esther Guiu Hernandez, Seh Ling Kwong, Phoebe Macrae, Maggie-Lee Huckabee
Summary: This study investigated the potential for behavioral modulation of resting pressure at the upper esophageal sphincter (UOS) in healthy adults. Participants were able to increase resting pressure after one week of training, but there was no evidence for purposeful pressure decrease. The capacity for purposeful pressure modulation was influenced by intensive biofeedback training, while healthy subjects may be limited by physiological factors.
Article
Otorhinolaryngology
Simone Miller, Martin Ptok, Michael Jungheim
Summary: This study investigated the UES reaction to different levels of acidity during swallowing, finding prolonged Restitution Times with stronger acid boluses. Significant differences were found towards neutral and less acidic boluses. Post-Swallow Maximum and Period of Sphincter Activity varied significantly, with higher values for the strongest acid bolus. Relaxation Times showed a slight trend of prolongation with higher bolus acidity, suggesting reflexive protective mechanisms triggered by receptors in the pharyngeal mucosa or UES.
Article
Medicine, General & Internal
Karoline Kussik de Almeida Leite, Fernanda Chiarion Sassi, Iago Navas Perissinotti, Luiz Roberto Comerlatti, Claudia Regina Furquim de Andrade
Summary: This study aimed to identify independent risk factors associated with severe restriction of oral intake in patients with acute ischemic stroke. The results showed that increasing age and dysarthria were associated with a higher probability of severe restriction of oral intake at hospital outcome.
Article
Biophysics
Kechen Shu, James L. Coyle, Subashan Perera, Yassin Khalifa, Aliaa Sabry, Ervin Sejdic
Summary: This study aimed to investigate the correlation between high-resolution cervical auscultation (HRCA) signals and maximal upper esophageal sphincter (UES) opening measured from videofluoroscopy recordings. The results showed that HRCA signal features were significantly associated with the normalized anterior-posterior distension of UES opening, with a stronger correlation observed during the duration of UES opening.
PHYSIOLOGICAL MEASUREMENT
(2021)
Article
Medicine, General & Internal
Daniel L. Cohen, Ram Dickman, Anton Bermont, Vered Richter, Haim Shirin, Amir Mari
Summary: Patients with absent contractility (AC) have more esophageal symptoms and require more intense gastrointestinal follow-up than controls. Only a minority of patients with AC have underlying rheumatologic disease. Those without rheumatologic disease at baseline did not subsequently develop one, suggesting that a rheumatologic evaluation is likely unnecessary. The clinical course of AC in patients with rheumatologic disease and those without appears to be similar.
JOURNAL OF CLINICAL MEDICINE
(2022)
Article
Biology
Amol Bhandare, Joseph van de Wiel, Reno Roberts, Ingke Braren, Robert Huckstepp, Nicholas Dale
Summary: Regulation of systemic PCO2 is a life-preserving mechanism. The RTN, Raphe, and pF(L) in the medulla oblongata play important roles in CO2 chemosensory and respiratory adaptive changes in awake adult mice during hypercapnia. The activity of these nuclei differs in temporal characteristics and CO2 sensitivity, suggesting coordinated generation of adaptive ventilatory responses.
Article
Multidisciplinary Sciences
Jonathan Trevorrow Clark, Anindya Ganguly, Jadrian Ejercito, Matthew Luy, Anupama Dahanukar, Anandasankar Ray
Summary: Basic volatiles like ammonia have an inhibitory effect on olfactory and gustatory receptor neurons in fruit flies and mosquitoes, preventing them from firing action potentials to their ligands. This inhibition is accompanied by an increase in calcium in antennal cells. The concentration at which these neurons are inhibited also reduces the response to attractive ligands and attraction to human skin odor. These findings have implications for insect control.
Article
Medicine, Research & Experimental
Kevin Renz Ambrocio, Reagan Ramsey, Ashli O'Rourke, Jonathan Beall, Kendrea L. Garand
Summary: Age, sex, and swallow task can influence the normal timing and extent of upper esophageal sphincter (UES) movement, and these factors should be considered in clinical decision-making.
Review
Pediatrics
Xu Zhang, Hongxiang Wang, Fan Hong, Tao Xu, Juxiang Chen
Summary: Teratoma in the medulla oblongata is extremely rare and can cause severe brain stem compression and potentially fatal impairment. Surgical removal followed by continuous rehabilitation is the preferred treatment, with good outcomes in terms of mobility and prevention of local recurrence.
FRONTIERS IN PEDIATRICS
(2021)
Article
Pathology
Hyo Sum Kwon, Dong Hoon Shin, So Young Kim, Chung Su Hwang, Arhong Kim, Hyun Jung Lee, JooYoung Na, Jung Hee Lee, Jee Yeon Kim
Summary: This study evaluated the feasibility of using DNA extracted from differently prepared cytologic slides for PCR-based molecular tests. The results showed that mutation testing worked well for most samples, except for CytoRich Red Preservative-fixed slides. This indicates that stained and unstained cytologic slides are a suitable source for PCR-based molecular tests, as long as they are fixed in ethanol or stored in an air-dried condition for a short time.
Article
Anatomy & Morphology
Hyeng-Kyu Park, Jae-Young Han, Young-Suk Cho, Kwang-Il Nam
Summary: The tensor of the vastus intermedius (TVI) originated from the anteroinferior greater trochanter and inserts into the upper patella. It has been overlooked but warrants more research due to the development of micro-surgery and detailed rehabilitation treatments.
Editorial Material
Cardiac & Cardiovascular Systems
Ji Hoon Lim, Soo Yong Lee, Joo-Young Na, Ga Yun Kim, Ji Soo Oh, Seok Hyun Kim
KOREAN CIRCULATION JOURNAL
(2023)
Article
Cardiac & Cardiovascular Systems
Jidong Sung, Chul Kim, Jae-Young Han, Sungju Jee, Jang Woo Lee, Jong Hwa Lee, Won-Seok Kim, Heui Je Bang, Sora Baek, Kyung-Lim Joa, Ae Ryoung Kim, So Young Lee, Jihee Kim, Chung Reen Kim, Oh Pum Kwon
Summary: The comprehensiveness of cardiac rehabilitation programs in Korea is inadequate, with only a minority of hospitals offering multidisciplinary interventions. Furthermore, there is a shortage of dedicated personnel for these programs. Increased awareness and improved insurance reimbursement for educational programs are necessary.
BMC CARDIOVASCULAR DISORDERS
(2023)
Article
Pathology
Jung Hee Lee, Yong Jun Kim, Hyun Woo Ryu, Seung Won Shin, Eun Ji Kim, So Hyun Shin, Joon Young Park, So Young Kim, Chung Su Hwang, Joo-Young Na, Dong Hoon Shin, Jee Yeon Kim, Hyun Jung Lee
Summary: This study is the first to investigate the expression of B7-H3 and PD-L1 and their association with survival in ccRCC. The results showed that B7-H3 expression is associated with poor progression-free survival and is an independent prognostic factor for ccRCC.
DIAGNOSTIC PATHOLOGY
(2023)
Article
Medicine, General & Internal
Jae In Lee, Jae-Young Han, Hae-Bin Gwak, Chang-Won Moon, Min Kyun Sohn, Sungju Jee, Chul Kim
Summary: This study aims to compare the effect of providing financial incentives to post-MI patients referred for outpatient cardiac rehabilitation (CR) and to confirm the effect of increasing CR participation and completion rates. It will be a single-blind, pragmatic, randomized controlled trial conducted at 2 tertiary hospitals. The primary outcomes will be used to assess the CR participation rate and completion, as well as compare changes in cardiorespiratory function, activity scale index, EuroQol 5 dimensions, and patient health questionnaire.
Article
Medicine, General & Internal
Peel Jung, Hyung Wook Kim, Su Bum Park, Dae Hwan Kang, Cheol Woong Choi, Su Jin Kim, Hyeong Seok Nam, Dae Gon Ryu, Dong Hoon Shin, Joo Young Na, Mi Sook Yun
Summary: This study retrospectively collected clinical, endoscopic, and pathological data of 254 SSLs and found that SSLs patients with older age, metabolic diseases, and high-risk adenomas were at higher risk of dysplasia and carcinoma. Additionally, SSLs located in the distal colon, with larger size, polypoid morphology, surface-changes, no mucus cap, and categorized as NICE type 2/3 were also associated with an increased risk of dysplasia and carcinoma in SSLs. Therefore, the clinical and endoscopic characteristics can aid in the diagnosis and management of SSLs with dysplasia and carcinoma.
KOREAN JOURNAL OF INTERNAL MEDICINE
(2023)
Article
Medicine, Legal
Dae Geon Kim, Hae-Sung Choi, Tae Hwan Lee, Joo-Young Na
Summary: The Abbreviated Injury Scale (AIS) and Injury Severity Score (ISS) are important evaluation tools used in clinical practice to determine the degree of injury in trauma patients. However, their application in forensic medicine is limited. This study introduced a system called the Forensic Injury Severity Score Template (FISST) that can objectively and quantitatively evaluate the severity of postmortem injuries. The FISST scores showed statistically significant differences between different types of deaths and trauma-related death subtypes.
FORENSIC SCIENCE MEDICINE AND PATHOLOGY
(2023)
Review
Rehabilitation
Ki-Hong Kim, Jae-Young Han
Summary: Cardiac rehabilitation is a well-established program that is recognized globally for its benefits in restoring cardiopulmonary function and improving overall well-being. However, in Korea, it is underutilized and this fact sheet highlights the current status and challenges of implementing cardiac rehabilitation in Korea.
ANNALS OF REHABILITATION MEDICINE-ARM
(2023)
Article
Rehabilitation
San-Ha Kim, Jae-Young Han, Min-Keun Song, In Sung Choi, Hyeng-Kyu Park
Summary: This article reports an unusual case of orthostatic tremor in an 18-year-old male patient after trauma, which was successfully resolved through multimodal therapy including botulinum toxin injection. Comprehensive rehabilitative treatment is necessary in the management of OT as it significantly affects the patient's quality of life.
TURKISH JOURNAL OF PHYSICAL MEDICINE AND REHABILITATION
(2023)
Article
Cell Biology
Jung Hee Lee, Dong Hoon Shin, Sang Yull Lee, Jun Young Park, So Young Kim, Chung Su Hwang, Hyun Jung Lee, Joo Young Na, Jee Yeon Kim
Summary: This study compared the expressions of NOL4 and CD56 in different types of lung tumors. NOL4 showed higher specificity and positive predictive value for lung NENs, making it a potential adjunctive diagnostic marker. NOL4 retained its nuclear immunoreactivity even in areas of crush artifact or necrosis.
HISTOLOGY AND HISTOPATHOLOGY
(2022)
Article
Medicine, General & Internal
Dae-Hyun Kim, Seok-Joo Moon, Juneyoung Lee, Jae-Kwan Cha, Moo Hyun Kim, Jong-Sung Park, Byeolnim Ban, Jihoon Kang, Beom Joon Kim, Won-Seok Kim, Chang-Hwan Yoon, Heeyoung Lee, Seongheon Kim, Eun Kyoung Kang, Ae-Young Her, Cindy W. Yoon, Joung-Ho Rha, Seong-Ill Woo, Won Kyung Lee, Han -Young Jung, Jang Hoon Lee, Hun Sik Park, Yang-Ha Hwang, Keonyeop Kim, Rock Bum Kim, Nack-Cheon Choi, Jinyong Hwang, Hyun-Woong Park, Ki Soo Park, SangHak Yi, Jae Young Cho, Nam-Ho Kim, Kang-Ho Choi, Juhan Kim, Jae-Young Han, Jay Chol Choi, Song-Yi Kim, Joon-Hyouk Choi, Jei Kim, Min Kyun Sohn, Si Wan Choi, Dong-Ick Shin, Sang Yeub Lee, Jang-Whan Bae, Kun Sei Lee, Hee-Joon Bae
Summary: Factors associated with direct admission to regional cardiocerebrovascular centers differed between acute ischemic stroke (AIS) and acute myocardial infarction (AMI). The use of emergency medical service (EMS) was found to be a crucial factor in determining hospital admission for both conditions.
JOURNAL OF KOREAN MEDICAL SCIENCE
(2022)
Article
Medicine, General & Internal
Chul Kim, Jidong Sung, Jae-Young Han, Sungju Jee, Jang Woo Lee, Jong Hwa Lee, Won-Seok Kim, Heui Je Bang, Sora Baek, Kyung Lim Joa, Ae Ryoung Kim, So Young Lee, Jihee Kim, Chung Reen Kim, Oh Pum Kwon
Summary: Through a nationwide survey, it was found that most regional medical and public health management institutions in Korea are unprepared for the implementation of community-based cardiac rehabilitation (CR) programs. While many institutions have the necessary facilities for exercise training, there is a lack of patient-monitoring systems during exercise, and institutions are burdened with the cost of establishing personnel and facilities for CR.
JOURNAL OF KOREAN MEDICAL SCIENCE
(2022)
Article
Medicine, General & Internal
Seok Hyun Kim, Soo Yong Lee, Ga Yun Kim, Ji Soo Oh, Jeongsu Kim, Kook Jin Chun, Min Ho Ju, Chee-Hoon Lee, Yeo-Jeong Song, Joo-Young Na
Summary: Fulminant myocarditis is a rare but potentially fatal complication following ChAdOx1 nCoV-19 vaccination, as described in this case study of a 63-year-old woman who was salvaged by heart transplantation.
JOURNAL OF KOREAN MEDICAL SCIENCE
(2022)
Article
Medicine, General & Internal
Dong-Hoon Kang, Joo-Young Na, Jun-Ho Yang, Seong-Ho Moon, Sung-Hwan Kim, Jae-Jun Jung, Ho-Jeong Cha, Jong-Hwa Ahn, Yong-Whi Park, Sang-Yeong Cho, Ho-Kyung Yu, Soo-Hee Lee, Mi-Yeong Park, Jong-Woo Kim, Joung-Hun Byun
Summary: A female patient developed acute fulminant myocarditis after receiving COVID-19 vaccination and eventually underwent heart transplantation. Autopsy findings suggested a possible link between giant cell myocarditis and vaccination. Clinicians should be aware of the potential development of giant cell myocarditis after COVID-19 vaccination.
MEDICINA-LITHUANIA
(2022)