Review
Cell Biology
Abdelhady Osman, Nellie Kamkar, Mark Speechley, Shehzad Ali, Manuel Montero-Odasso
Summary: The purpose of this review was to systematically evaluate the association between FRIDs and gait performance in community-dwelling older adults without neurological movement disorders. The study found that drugs with sedative properties are associated with reduced gait speed in older adults, while statin use has no association with gait speed. There is insufficient evidence on the association between FRIDs and other gait performance measures.
AGEING RESEARCH REVIEWS
(2022)
Article
Geriatrics & Gerontology
Jonathan Hauff, Marietta Rottenkolber, Patrick Oehler, Sebastian Fischer, Jochen Gensichen, Michael Drey, G. Caleb Alexander, Bruce Guthrie, Tobias Dreischulte
Summary: This study investigated the risk of falls in individuals aged 65 years and older, and found that certain drug groups were associated with an absolute increase in risk. The results showed that older individuals, especially those aged 75 years and older, who were prescribed specific medications (such as selective serotonin reuptake inhibitors, tricyclic antidepressants, antipsychotics, and three or more fall-risk-increasing drugs) had a significantly higher absolute risk of fractures.
Review
Medicine, General & Internal
Shaghayegh Modaberi, Esmaeel Saemi, Peter A. Federolf, Steven van Andel
Summary: Lockdowns implemented during the COVID-19 pandemic may lead to detraining effects on balance outcomes, especially for older adults. Programs focusing on improving balance are more resistant to detraining, but some signs of detraining start to show even in these specific programs. More studies are needed to confirm these results due to the limited number of included studies in the review.
JOURNAL OF CLINICAL MEDICINE
(2021)
Article
Geriatrics & Gerontology
Lotta J. Seppala, Mirko Petrovic, Jesper Ryg, Gulistan Bahat, Eva Topinkova, Katarzyna Szczerbinska, Tischa J. M. van der Cammen, Sirpa Hartikainen, Birkan Ilhan, Francesco Landi, Yvonne Morrissey, Alpana Mair, Marta Gutierrez-Valencia, Marielle H. Emmelot-Vonk, Maria Angeles Caballero Mora, Michael Denkinger, Peter Crome, Stephen H. D. Jackson, Andrea Correa-Perez, Wilma Knol, George Soulis, Adalsteinn Gudmundsson, Gijsbertus Ziere, Martin Wehling, Denis O'Mahony, Antonio Cherubini, Nathalie van der Velde
Summary: Healthcare professionals are often reluctant to deprescribe fall-risk-increasing drugs, leading to the development of STOPPFall and a deprescribing tool by a European expert group. Through an expert Delphi consensus process, 14 medication classes were included in STOPPFall, with practical deprescribing guidance developed for these classes. Evaluation of the effectiveness of these tools in falls prevention is recommended.
Article
Geriatrics & Gerontology
Steven Phu, Michela Persiani, Brandon Tan, Matthew Brodie, Simon Gandevia, Daina L. Sturnieks, Stephen R. Lord
Summary: This study examined the effects of optic flow stimuli presented in different directions on postural stability in young and older adults. The results showed that optic flow stimuli increased postural sway and muscle activity, with a greater impact on older adults, particularly in the mediolateral plane for those at high risk of falls.
EXPERIMENTAL GERONTOLOGY
(2023)
Review
Chemistry, Multidisciplinary
Hunter Derby, Harish Chander, Sachini N. K. Kodithuwakku Arachchige, Alana J. Turner, Adam C. Knight, Reuben Burch, Charles Freeman, Chip Wade, John C. Garner
Summary: Understanding the impact of design features on postural control and locomotion variables can lead to better design modifications for work boots. This review summarizes a series of studies that tested three different work boots and their effect on biomechanical and physiological variables. The findings provide suggestions for optimal work boot design and selection to enhance human performance and safety.
APPLIED SCIENCES-BASEL
(2023)
Review
Health Policy & Services
Hammad Alhasan, Mansour Abdullah Alshehri, Patrick C. Wheeler, Daniel T. P. Fong
Summary: The systematic review found that interactive video games training has a positive effect on postural control in frail and pre-frail older adults, but it does not significantly reduce the risk of falls. Therefore, caution should be exercised when prescribing it for frail older adults.
GAMES FOR HEALTH JOURNAL
(2021)
Review
Sport Sciences
Elena M. Bonke, Julia Southard, Thomas A. Buckley, Claus Reinsberger, Inga K. Koerte, David R. Howell
Summary: This systematic review investigated the association between repetitive head impacts and postural control. The findings were heterogeneous, with a tendency towards no significant effects of repetitive head impacts on clinical postural control measures. Future studies on different athlete populations are needed to further explore the effects of repetitive head impacts.
JOURNAL OF SCIENCE AND MEDICINE IN SPORT
(2021)
Article
Health Policy & Services
Cheng-Wen Tien, Hsien-Te Peng, Hsuen-Ying Peng, Chen-Yi Song
Summary: This study found that mat exergame-based multicomponent training has positive effects on the static and dynamic standing balance capacities of older adults. Significant improvements were observed in the high-risk group, while medium effect sizes were noted in the low-risk group after the intervention.
GAMES FOR HEALTH JOURNAL
(2022)
Review
Health Care Sciences & Services
Wenhui Mao, Ting Wang, Mengzi Sun, Fangtong Zhang, Li Li
Summary: This systematic review suggests that Tai Chi has positive effects on postural control in patients with peripheral neuropathy, including reducing sway area, increasing walking distance, and improving performance in timed-up-and-go test.
Article
Cardiac & Cardiovascular Systems
Esther Liu, Musarrat Nahid, Mahad Musse, Ligong Chen, Sarah N. Hilmer, Andrew Zullo, Min Ji Kwak, Mark Lachs, Emily B. Levitan, Monika M. Safford, Parag Goyal
Summary: This study investigated the use of fall risk-increasing drugs (FRIDs) among older adults hospitalized for heart failure (HF) and found that almost all patients were prescribed FRIDs during hospitalization and at discharge, leading to a high risk of falls after discharge.
BMC CARDIOVASCULAR DISORDERS
(2023)
Article
Geriatrics & Gerontology
Taylor R. Elliott, Susan Westneat, Shama D. Karanth, Erin L. Abner, Anna M. Kucharska-Newton, Daniela C. Moga
Summary: Investigation into whether an injurious fall is associated with being prescribed a new FRID showed a non-statistically significant increase, which may depend on age.
Article
Geriatrics & Gerontology
Karina Alves Ramos, Enrico Antonio Colosimo, Yeda Aparecida de Oliveira Duarte, Fabiola Bof de Andrade
Summary: Polypharmacy, or the use of multiple medications, is associated with a higher risk of falls among older adults. However, the specific association between polypharmacy and falls, independent of Fall-Risk Increasing Drugs (FRIDs), has not been extensively explored. This longitudinal study in Brazil found that the association between polypharmacy and falls was significantly attenuated after considering FRID use, suggesting that minimizing the number of medications and avoiding FRIDs could help prevent falls among older adults.
ARCHIVES OF GERONTOLOGY AND GERIATRICS
(2023)
Review
Biology
Pablo Valdes-Badilla, Rodrigo Ramirez-Campillo, Tomas Herrera-Valenzuela, Braulio Henrique Magnani Branco, Eduardo Guzman-Munoz, Guillermo Mendez-Rebolledo, Yeny Concha-Cisternas, Jordan Hernandez-Martinez
Summary: Regular physical activity has become more popular as a strategy for fall prevention and improving the health of older adults. However, the COVID-19 pandemic requires the reassessment of strategies to promote active and healthy aging, including maintaining social distance and exercising at home. Olympic combat sports can be a suitable option as they can be practiced with a limited number of participants in reduced spaces. However, more high-quality studies are needed to determine the effectiveness of Olympic combat sports in improving balance and reducing fall risks for older adults.
Article
Sport Sciences
Sarah A. Wilson, Kimi D. Dahl, Kristin M. Dunford, Jacqueline N. Foody, Payam Zandiyeh, Travis Lee Turnbull, Scott Tashman
Summary: The study aimed to investigate the impact of canting wedges inserted under ski boots on knee kinematics/kinetics, balance, and neuromuscular activity in recreational alpine skiers. The experimental findings showed that wedges on the medial side of the foot significantly improved skier kinematics and kinetics while also positively influencing postural control measures associated with balance quality.
JOURNAL OF SCIENCE AND MEDICINE IN SPORT
(2021)
Article
Multidisciplinary Sciences
Yuhan Zhou, Robbin Romijnders, Clint Hansen, Jos van Campen, Walter Maetzler, Tibor Hortobagyi, Claudine J. C. Lamoth
SCIENTIFIC REPORTS
(2020)
Article
Neurosciences
Lisanne B. M. Bakker, Tulika Nandi, Claudine J. C. Lamoth, Tibor Hortobagyi
Summary: A single balance training session can significantly improve performance in the trained task and retain the improvement after a week, but the transferability to other tasks is not statistically significant. Further research is needed to understand the underlying neural mechanisms of rapid balance skill acquisition, retention, and transfer.
HUMAN MOVEMENT SCIENCE
(2021)
Article
Geriatrics & Gerontology
Paulo Cezar Rocha dos Santos, Claudine J. C. Lamoth, Lilian Teresa Bucken Gobbi, Inge Zijdewind, Fabio Augusto Barbieri, Tibor Hortobagyi
Summary: The study compared muscle activation patterns of older and younger adults during repetitive sit-to-stand tasks, finding that older adults activated certain muscles more, earlier, and for longer duration. Despite completing fewer STS trials, older adults reported similar perceived exertion levels as younger adults. Maximum voluntary isometric knee extension force decreased at the end of the task, with similar declines in muscle activation levels across different age groups.
FRONTIERS IN AGING NEUROSCIENCE
(2021)
Article
Engineering, Biomedical
Iris Hagoort, Tibor Hortobagyi, Nicolas Vuillerme, Claudine J. C. Lamoth, Alessio Murgia
Summary: The effects of age on muscle architecture parameters were examined in this study. The results showed that muscle-specificity and age influenced the relationships between muscle architecture parameters during rest. Furthermore, the reliability of muscle architecture parameters assessed using 2D panoramic ultrasound was found to be acceptable, although it varied depending on age, muscle, and measurement parameter.
BIOMEDICAL ENGINEERING ONLINE
(2022)
Article
Engineering, Biomedical
S. B. Swart, A. R. den Otter, C. J. C. Lamoth
Summary: This article introduces a data-driven method called Singular Spectrum Analysis (SSA) to assess the global trend in motor adaptation. Through comparisons using simulated and real data, it was found that SSA more accurately reconstructed the global trends compared to traditional filtering and fitting methods.
BIOMEDICAL SIGNAL PROCESSING AND CONTROL
(2022)
Article
Biology
Xiaoping Zheng, Michiel F. Reneman, Jone Ansuategui Echeita, Rita H. R. Schiphorst Preuper, Herbert Kruitbosch, Egbert Otten, Claudine J. C. Lamoth
Summary: This study found that patients with chronic low back pain (CLBP) exhibit different motor control strategies, with CLBP- patients showing a looser and more stable gait, while CLBP+ patients showing a more regular, less variable, and more predictable gait pattern.
COMPUTERS IN BIOLOGY AND MEDICINE
(2022)
Article
Geriatrics & Gerontology
Hans Wouters, Jos P. Van Campen, Marloes J. Kuitert, Lisette Kikkert, Sarah N. Hilmer, Katja Taxis, Helene G. Van der Meer, Claudine J. C. Lamoth
Summary: This study found that in older patients with comorbidities, high cumulative exposure to anticholinergic and sedative medications is associated with poorer function on multiple gait dimensions, particularly showing stronger associations with the Regularity and Pace dimensions.
Review
Chemistry, Analytical
Mariano Bernaldo de Quiros, E. H. Douma, Inge van den Akker-scheek, Claudine J. C. Lamoth, Natasha M. Maurits
Summary: This review examines the use of wearable sensors to measure movement in stroke patients and evaluates the relationship between sensor-based outcomes and existing clinical evaluation methods. The results show that sensor-based measures provide additional information for understanding patient behavior and recovery beyond what clinical evaluations can provide.
Article
Neurosciences
Iris Hagoort, Nicolas Vuillerme, Tibor Hortobagyi, Claudine J. C. Lamoth
Summary: The relationship between walking speed and quantitative and qualitative gait measures depends on the type of gait measure studied. At speeds below 1.20 m.s(-1), walking speed has a greater impact on gait measures. Decreasing walking speed results in shorter strides, longer stride times, lower stride frequency for quantitative measures, and decreases in gait symmetry, stability, and regularity for qualitative measures.
Article
Neurosciences
Tom J. W. Buurke, Nikita Sharma, Sander B. Swart, Lucas H. V. van der Woude, Rob den Otter, Claudine J. C. Lamoth
Summary: This study demonstrates that healthy adults are able to retain savings in split-belt adaptation over a three-week period, indicating the importance of including only naive split-belt walkers in such studies. These findings can be used to compare with long-term savings in patient groups to gain insights into successful gait training in rehabilitation.
Article
Rehabilitation
Michiel F. Reneman, Jone Ansuategui Echeita, Klaske van Kammen, Henrika R. Schiphorst Preuper, Rienk Dekker, Claudine J. C. Lamoth
Summary: The study aims to analyze the time spent on moderate to vigorous physical activity (MVPA) by patients with chronic low back pain (CLBP) admitted to pain rehabilitation and compare it to the WHO recommendations. The results show that a minority of patients meet the WHO recommended MVPA level of 2010, while the more lenient recommendation of 2020 is met by a higher percentage of patients.
MUSCULOSKELETAL SCIENCE AND PRACTICE
(2022)
Article
Computer Science, Interdisciplinary Applications
Xiaoping Zheng, Michiel F. Reneman, Rita H. R. Schiphorst Preuper, Egbert Otten, Claudine J. C. Lamoth
Summary: This study used advanced unsupervised machine learning, Hidden semi-Markov model (HSMM), to investigate the physical activity intensity patterns in patients with chronic low back pain (CLBP). The results showed that there were differences in physical activity intensity patterns between CLBP- and CLBP + patients, with CLBP + patients engaging in longer bouts of activity.
COMPUTER METHODS AND PROGRAMS IN BIOMEDICINE
(2023)
Article
Neurosciences
Iris Hagoort, Nicolas Vuillerme, Tibor Hortobagyi, Claudine J. C. Lamoth
Summary: The aim of this study was to determine the effects of age and walking conditions on gait performance. The results showed that walking conditions influenced all aspects of gait, while age only affected the time & frequency domain. Older adults exhibited higher variability, lower stability, and lower time & frequency in gait during straight walking and treadmill walking.
HUMAN MOVEMENT SCIENCE
(2023)
Article
Physiology
S. B. Swart, A. R. den Otter, C. J. C. Lamoth
Summary: In this study, the researchers used a split-belt paradigm to examine how age affects the flexibility and adaptability of walking. They found that while flexibility decreased with age, adaptability was not affected.
FRONTIERS IN PHYSIOLOGY
(2023)
Review
Sport Sciences
Jaap H. van Dieen, Maarten R. Prins, Sjoerd M. Bruijn, Wen Hua Wu, Bowei Liang, Claudine J. C. Lamoth, Onno G. Meijer
Summary: Chronic low back pain patients exhibit reduced thorax-pelvis relative phase shift towards out-of-phase movement with increasing speed compared to healthy controls. This change is associated with factors such as trunk muscle activity, stride frequency, and magnitude of pelvis rotations. Ultimately, thorax-pelvis relative phase is not a reliable indicator of trunk stiffness due to the multiple interacting factors influencing it.
JOURNAL OF HUMAN KINETICS
(2021)