The Challenges of Gout Management in the Elderly

Prevalence of Contraindications and Prescription of Pharmacologic Therapies for Gout

(2011) Robert T. Keenan et al.   AMERICAN JOURNAL OF MEDICINE

NSAID Use Selectively Increases the Risk of Non-Fatal Myocardial Infarction: A Systematic Review of Randomised Trials and Observational Studies

(2011) Luis Alberto García Rodríguez et al.   PLoS One

Association of Uric Acid With Change in Kidney Function in Healthy Normotensive Individuals

(2010) Gianni Bellomo et al.   AMERICAN JOURNAL OF KIDNEY DISEASES

The appropriate use of non-steroidal anti-inflammatory drugs in rheumatic disease: opinions of a multidisciplinary European expert panel

(2010) G. Burmester et al.   ANNALS OF THE RHEUMATIC DISEASES

Gout, Allopurinol Use, and Heart Failure Outcomes

(2010) George Thanassoulis   ARCHIVES OF INTERNAL MEDICINE

High versus low dosing of oral colchicine for early acute gout flare: Twenty-four-hour outcome of the first multicenter, randomized, double-blind, placebo-controlled, parallel-group, dose-comparison colchicine study

(2010) Robert A. Terkeltaub et al.   ARTHRITIS AND RHEUMATISM

Canakinumab for the treatment of acute flares in difficult-to-treat gouty arthritis: Results of a multicenter, phase II, dose-ranging study

(2010) Alexander So et al.   ARTHRITIS AND RHEUMATISM

Using allopurinol above the dose based on creatinine clearance is effective and safe in patients with chronic gout, including those with renal impairment

(2010) Lisa K. Stamp et al.   ARTHRITIS AND RHEUMATISM

Effect of hydrochlorothiazide on the pharmacokinetics and pharmacodynamics of febuxostat, a non-purine selective inhibitor of xanthine oxidase

(2010) Brian Grabowski et al.   BRITISH JOURNAL OF CLINICAL PHARMACOLOGY

Effect of Allopurinol in Chronic Kidney Disease Progression and Cardiovascular Risk

(2010) M. Goicoechea et al.   Clinical Journal of the American Society of Nephrology

High-Normal Serum Uric Acid Increases Risk of Early Progressive Renal Function Loss in Type 1 Diabetes: Results of a 6-year follow-up

(2010) L. H. Ficociello et al.   DIABETES CARE

Should Nonsteroidal Anti-Inflammatory Drugs (NSAIDs) be Prescribed to the Older Adult?

(2010) Robert L. Barkin et al.   DRUGS & AGING

Effect of high-dose allopurinol on exercise in patients with chronic stable angina: a randomised, placebo controlled crossover trial

(2010) Awsan Noman et al.   LANCET

Gout therapeutics: new drugs for an old disease

(2010) Christopher M Burns et al.   LANCET

The urate-lowering efficacy and safety of febuxostat in the treatment of the hyperuricemia of gout: the CONFIRMS trial

(2010) Michael A Becker et al.   ARTHRITIS RESEARCH & THERAPY

The interleukin 1 inhibitor rilonacept in treatment of chronic gouty arthritis: results of a placebo-controlled, monosequence crossover, non-randomised, single-blind pilot study

(2009) R Terkeltaub et al.   ANNALS OF THE RHEUMATIC DISEASES

Acid-related disorders in the elderly

(2009) Marilisa Franceschi et al.   BEST PRACTICE & RESEARCH IN CLINICAL GASTROENTEROLOGY

The role of hyperuricemia in vascular disorders

(2009) N Lawrence Edwards   CURRENT OPINION IN RHEUMATOLOGY

A Benefit-Risk Assessment of Benzbromarone in the Treatment of Gout

(2009) Ming-Han H Lee et al.   DRUG SAFETY

Gender-dependent impacts of body mass index and moderate alcohol consumption on serum uric acid—an index of oxidant stress status?

(2009) Päivikki I. Alatalo et al.   FREE RADICAL BIOLOGY AND MEDICINE

The prognostic impact of allopurinol in patients with acute myocardial infarction undergoing primary percutaneous coronary intervention

(2009) E. Rentoukas et al.   INTERNATIONAL JOURNAL OF CARDIOLOGY

Clinical Efficacy and Safety of Successful Longterm Urate Lowering with Febuxostat or Allopurinol in Subjects with Gout

(2009) M. A. BECKER et al.   JOURNAL OF RHEUMATOLOGY

Febuxostat in the treatment of gout: 5-yr findings of the FOCUS efficacy and safety study

(2009) H. R. Schumacher et al.   RHEUMATOLOGY

Allopurinol and mortality in hyperuricaemic patients

(2009) A. J. Luk et al.   RHEUMATOLOGY

Efficacy and tolerability of urate-lowering drugs in gout: a randomised controlled trial of benzbromarone versus probenecid after failure of allopurinol

(2008) M K Reinders et al.   ANNALS OF THE RHEUMATIC DISEASES

Effects of febuxostat versus allopurinol and placebo in reducing serum urate in subjects with hyperuricemia and gout: A 28-week, phase III, randomized, double-blind, parallel-group trial

(2008) H. RALPH Schumacher et al.   ARTHRITIS AND RHEUMATISM

Febuxostat

(2008) Philip I Hair et al.   DRUGS

The Effect of Age and Gender on Pharmacokinetics, Pharmacodynamics, and Safety of Febuxostat, a Novel Nonpurine Selective Inhibitor of Xanthine Oxidase

(2008) Reza Khosravan et al.   JOURNAL OF CLINICAL PHARMACOLOGY

Use of oral prednisolone or naproxen for the treatment of gout arthritis: a double-blind, randomised equivalence trial

(2008) Hein JEM Janssens et al.   LANCET

Colchicine Update: 2008

(2008) Robert A. Terkeltaub   SEMINARS IN ARTHRITIS AND RHEUMATISM

In vitrodrug–drug interaction studies with febuxostat, a novel non-purine selective inhibitor of xanthine oxidase: plasma protein binding, identification of metabolic enzymes and cytochrome P450 inhibition

(2008) M. Mukoyoshi et al.   XENOBIOTICA

Menopause, postmenopausal hormone use and serum uric acid levels in US women – The Third National Health and Nutrition Examination Survey

(2008) A Elisabeth Hak et al.   ARTHRITIS RESEARCH & THERAPY

Effect of food or antacid on pharmacokinetics and pharmacodynamics of febuxostat in healthy subjects

(2007) Reza Khosravan et al.   BRITISH JOURNAL OF CLINICAL PHARMACOLOGY