Organophosphorus hydrolase as an in vivo catalytic nerve agent bioscavenger

A Gas Chromatographic-Mass Spectrometric Approach to Examining Stereoselective Interaction of Human Plasma Proteins with Soman*

(2013) David T. Yeung et al.   JOURNAL OF ANALYTICAL TOXICOLOGY

Protective efficacy of catalytic bioscavenger, paraoxonase 1 against sarin and soman exposure in guinea pigs

(2011) Manojkumar Valiyaveettil et al.   BIOCHEMICAL PHARMACOLOGY

Directed evolution of hydrolases for prevention of G-type nerve agent intoxication

(2011) Rinkoo D Gupta et al.   Nature Chemical Biology

Nerve Agent Hydrolysis Activity Designed into a Human Drug Metabolism Enzyme

(2011) Andrew C. Hemmert et al.   PLoS One

Organophosphate hydrolases as catalytic bioscavengers of organophosphorus nerve agents

(2011) Marie Trovaslet-Leroy et al.   TOXICOLOGY LETTERS

Evolution of and perspectives on therapeutic approaches to nerve agent poisoning

(2011) Patrick Masson   TOXICOLOGY LETTERS

Kinetics and Efficacy of an Organophosphorus Hydrolase in a Rodent Model of Methyl-parathion Poisoning

(2010) Chip Gresham et al.   ACADEMIC EMERGENCY MEDICINE

Efficient hydrolysis of the chemical warfare nerve agent tabun by recombinant and purified human and rabbit serum paraoxonase 1

(2010) Manojkumar Valiyaveettil et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Prophylaxis with human serum butyrylcholinesterase protects guinea pigs exposed to multiple lethal doses of soman or VX

(2010) Ashima Saxena et al.   BIOCHEMICAL PHARMACOLOGY

Purification and characterization of functional human paraoxonase-1 expressed in Trichoplusia ni larvae

(2010) Tamara C. Otto et al.   CHEMICO-BIOLOGICAL INTERACTIONS

Hyperthermophilic phosphotriesterases/lactonases for the environment and human health

(2010) Luigi Mandrich et al.   ENVIRONMENTAL TECHNOLOGY

Adenovirus-mediated human paraoxonase1 gene transfer to provide protection against the toxicity of the organophosphorus pesticide toxicant diazoxon

(2010) E G Duysen et al.   GENE THERAPY

Improved pharmacokinetics and immunogenicity profile of organophosphorus hydrolase by chemical modification with polyethylene glycol

(2010) Boris N. Novikov et al.   JOURNAL OF CONTROLLED RELEASE

Computational characterization of how the VX nerve agent binds human serum paraoxonase 1

(2010) Steven Z. Fairchild et al.   JOURNAL OF MOLECULAR MODELING

Gene-Delivered Butyrylcholinesterase Is Prophylactic against the Toxicity of Chemical Warfare Nerve Agents and Organophosphorus Compounds

(2010) K. Parikh et al.   JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS

Plant-derived human butyrylcholinesterase, but not an organophosphorous-compound hydrolyzing variant thereof, protects rodents against nerve agents

(2010) B. C. Geyer et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Chromatographic preparation and kinetic analysis of interactions between tabun enantiomers and acetylcholinesterase

(2010) O. Tenberken et al.   TOXICOLOGY LETTERS

Butyrylcholinesterase for protection from organophosphorus poisons: Catalytic complexities and hysteretic behavior

(2009) Patrick Masson et al.   ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS

Dramatic Differences in Organophosphorus Hydrolase Activity between Human and Chimeric Recombinant Mammalian Paraoxonase-1 Enzymes

(2009) Tamara C. Otto et al.   BIOCHEMISTRY

Functional Annotation and Three-Dimensional Structure of Dr0930 fromDeinococcus radiodurans, a Close Relative of Phosphotriesterase in the Amidohydrolase Superfamily†‡

(2009) Dao Feng Xiang et al.   BIOCHEMISTRY

Structural Insights into the Dual Activities of the Nerve Agent Degrading Organophosphate Anhydrolase/Prolidase

(2009) Nand K. Vyas et al.   BIOCHEMISTRY

Update on biochemical properties of recombinantPseudomonas diminutaphosphotriesterase

(2009) Eugénie Carletti et al.   JOURNAL OF ENZYME INHIBITION AND MEDICINAL CHEMISTRY

Reversed Enantioselectivity of Diisopropyl Fluorophosphatase against Organophosphorus Nerve Agents by Rational Design

(2009) Marco Melzer et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

A collaborative endeavor to design cholinesterase-based catalytic scavengers against toxic organophosphorus esters

(2008) Patrick Masson et al.   CHEMICO-BIOLOGICAL INTERACTIONS

Entry of Oximes into the Brain: A Review

(2008) D. Lorke et al.   CURRENT MEDICINAL CHEMISTRY

Engineered recombinant human paraoxonase 1 (rHuPON1) purified from Escherichia coli protects against organophosphate poisoning

(2008) R. C. Stevens et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Balancing the stability and the catalytic specificities of OP hydrolases with enhanced V-agent activities

(2008) T.E. Reeves et al.   PROTEIN ENGINEERING DESIGN & SELECTION