Bridging Islands of Information to Establish an Integrated Knowledge Base of Drugs and Health Outcomes of Interest

A pipeline to extract drug-adverse event pairs from multiple data sources

(2014) SriJyothsna Yeleswarapu et al.   BMC Medical Informatics and Decision Making

Connecting the Dots: Applications of Network Medicine in Pharmacology and Disease

(2013) A Jacunski et al.   CLINICAL PHARMACOLOGY & THERAPEUTICS

A Comparison of the Empirical Performance of Methods for a Risk Identification System

(2013) Patrick B. Ryan et al.   DRUG SAFETY

Empirical Performance of the Calibrated Self-Controlled Cohort Analysis Within Temporal Pattern Discovery: Lessons for Developing a Risk Identification and Analysis System

(2013) G. Niklas Norén et al.   DRUG SAFETY

Empirical Performance of the Self-Controlled Case Series Design: Lessons for Developing a Risk Identification and Analysis System

(2013) Marc A. Suchard et al.   DRUG SAFETY

Empirical Performance of a Self-Controlled Cohort Method: Lessons for Developing a Risk Identification and Analysis System

(2013) Patrick B. Ryan et al.   DRUG SAFETY

Empirical Performance of the Case–Control Method: Lessons for Developing a Risk Identification and Analysis System

(2013) David Madigan et al.   DRUG SAFETY

Empirical Performance of LGPS and LEOPARD: Lessons for Developing a Risk Identification and Analysis System

(2013) Martijn J. Schuemie et al.   DRUG SAFETY

Evaluating Performance of Risk Identification Methods Through a Large-Scale Simulation of Observational Data

(2013) Patrick B. Ryan et al.   DRUG SAFETY

Defining a Reference Set to Support Methodological Research in Drug Safety

(2013) Patrick B. Ryan et al.   DRUG SAFETY

Empirical Performance of a New User Cohort Method: Lessons for Developing a Risk Identification and Analysis System

(2013) Patrick B. Ryan et al.   DRUG SAFETY

Replication of the OMOP Experiment in Europe: Evaluating Methods for Risk Identification in Electronic Health Record Databases

(2013) Martijn J. Schuemie et al.   DRUG SAFETY

Evaluation of Disproportionality Safety Signaling Applied to Healthcare Databases

(2013) William DuMouchel et al.   DRUG SAFETY

Adverse Drug Events: Database Construction and in Silico Prediction

(2013) Feixiong Cheng et al.   Journal of Chemical Information and Modeling

DrugBank 4.0: shedding new light on drug metabolism

(2013) Vivian Law et al.   NUCLEIC ACIDS RESEARCH

Pharmacointeraction Network Models Predict Unknown Drug-Drug Interactions

(2013) Aurel Cami et al.   PLoS One

The Impact of Duration of Treatment on Reported Time-to-Onset in Spontaneous Reporting Systems for Pharmacovigilance

(2013) Ghazaleh Karimi et al.   PLoS One

Novel Data-Mining Methodologies for Adverse Drug Event Discovery and Analysis

(2012) R Harpaz et al.   CLINICAL PHARMACOLOGY & THERAPEUTICS

A Reference Standard for Evaluation of Methods for Drug Safety Signal Detection Using Electronic Healthcare Record Databases

(2012) Preciosa M. Coloma et al.   DRUG SAFETY

Emerging practices for mapping and linking life sciences data using RDF — A case series

(2012) M. Scott Marshall et al.   Journal of Web Semantics

Using Electronic Health Care Records for Drug Safety Signal Detection

(2012) Martijn J. Schuemie et al.   MEDICAL CARE

Consistency in the safety labeling of bioequivalent medications

(2012) Jon Duke et al.   PHARMACOEPIDEMIOLOGY AND DRUG SAFETY

Data-Driven Prediction of Drug Effects and Interactions

(2012) N. P. Tatonetti et al.   Science Translational Medicine

Empirical assessment of methods for risk identification in healthcare data: results from the experiments of the Observational Medical Outcomes Partnership

(2012) Patrick B. Ryan et al.   STATISTICS IN MEDICINE

Literature Based Drug Interaction Prediction with Clinical Assessment Using Electronic Medical Records: Novel Myopathy Associated Drug Interactions

(2012) Jon D. Duke et al.   PLoS Computational Biology

A Quantitative Analysis of Adverse Events and “Overwarning” in Drug Labeling

(2011) Jon Duke   ARCHIVES OF INTERNAL MEDICINE

Normalized names for clinical drugs: RxNorm at 6 years

(2011) Stuart J Nelson et al.   JOURNAL OF THE AMERICAN MEDICAL INFORMATICS ASSOCIATION

Validation of a common data model for active safety surveillance research

(2011) J Marc Overhage et al.   JOURNAL OF THE AMERICAN MEDICAL INFORMATICS ASSOCIATION

The ClinicalTrials.gov Results Database — Update and Key Issues

(2011) Deborah A. Zarin et al.   NEW ENGLAND JOURNAL OF MEDICINE

Disease Ontology: a backbone for disease semantic integration

(2011) L. M. Schriml et al.   NUCLEIC ACIDS RESEARCH

Predicting Adverse Drug Events Using Pharmacological Network Models

(2011) A. Cami et al.   Science Translational Medicine

Validation of Statistical Signal Detection Procedures in EudraVigilance Post-Authorization Data

(2010) Yolanda Alvarez et al.   DRUG SAFETY

Methods for Causality Assessment of Adverse Drug Reactions

(2009) Taofikat B Agbabiaka et al.   DRUG SAFETY

An Evaluation of Three Signal-Detection Algorithms Using a Highly Inclusive Reference Event Database

(2009) Alan M. Hochberg et al.   DRUG SAFETY

A quantitative approach of using genetic algorithm in designing a probability scoring system of an adverse drug reaction assessment system

(2007) Yvonne Koh et al.   INTERNATIONAL JOURNAL OF MEDICAL INFORMATICS