Nuclear receptors in bile acid metabolism

Mechanism of tissue-specific farnesoid X receptor in suppressing the expression of genes in bile-acid synthesis in mice

(2012) Bo Kong et al.   HEPATOLOGY

Bile acid receptors as targets for the treatment of dyslipidemia and cardiovascular disease

(2012) Geoffrey Porez et al.   JOURNAL OF LIPID RESEARCH

Targeting xenobiotic receptors PXR and CAR for metabolic diseases

(2012) Jie Gao et al.   TRENDS IN PHARMACOLOGICAL SCIENCES

Fibroblast Growth Factor 19 Treatment Ameliorates Disruption of Hepatic Lipid Metabolism in Farnesoid X Receptor (Fxr)-Null Mice

(2011) Masaaki Miyata et al.   BIOLOGICAL & PHARMACEUTICAL BULLETIN

FGF15/19 Regulates Hepatic Glucose Metabolism by Inhibiting the CREB-PGC-1α Pathway

(2011) Matthew J. Potthoff et al.   Cell Metabolism

PXR Prevents Cholesterol Gallstone Disease by Regulating Biosynthesis and Transport of Bile Salts

(2011) Jinhan He et al.   GASTROENTEROLOGY

The human gallbladder secretes fibroblast growth factor 19 into bile: Towards defining the role of fibroblast growth factor 19 in the enterobiliary tract

(2011) Serge J.L.B. Zweers et al.   HEPATOLOGY

Nuclear receptors in liver disease

(2011) Martin Wagner et al.   HEPATOLOGY

Pregnane X receptor activation induces FGF19-dependent tumor aggressiveness in humans and mice

(2011) Hongwei Wang et al.   JOURNAL OF CLINICAL INVESTIGATION

Changes of Organic Anion Transporter MRP4 and Related Nuclear Receptors in Human Obstructive Cholestasis

(2011) Jin Chai et al.   JOURNAL OF GASTROINTESTINAL SURGERY

FGF19 as a Postprandial, Insulin-Independent Activator of Hepatic Protein and Glycogen Synthesis

(2011) S. Kir et al.   SCIENCE

Role of nuclear receptors for bile acid metabolism, bile secretion, cholestasis, and gallstone disease

(2010) Thierry Claudel et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE

Regulation of Bile Acid Synthesis by Fat-soluble Vitamins A and D

(2010) Daniel R. Schmidt et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

A Novel Bile Acid-Activated Vitamin D Receptor Signaling in Human Hepatocytes

(2010) Shuxin Han et al.   MOLECULAR ENDOCRINOLOGY

Constitutive Androstane Receptor-Mediated Changes in Bile Acid Composition Contributes to Hepatoprotection from Lithocholic Acid-Induced Liver Injury in Mice

(2009) L. D. Beilke et al.   DRUG METABOLISM AND DISPOSITION

Master regulation of bile acid and xenobiotic metabolism via the FXR, PXR and CAR trio

(2009) Salvatore Modica   Frontiers in Bioscience-Landmark

Fibroblast Growth Factor-19, a Novel Factor That Inhibits Hepatic Fatty Acid Synthesis

(2009) Sushant Bhatnagar et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

FXR an emerging therapeutic target for the treatment of atherosclerosis

(2009) Andrea Mencarelli et al.   JOURNAL OF CELLULAR AND MOLECULAR MEDICINE

Bile acids: regulation of synthesis

(2009) John Y. L. Chiang   JOURNAL OF LIPID RESEARCH

Role of Bile Acids and Bile Acid Receptors in Metabolic Regulation

(2009) Philippe Lefebvre et al.   PHYSIOLOGICAL REVIEWS

Bile acid-activated receptors in the treatment of dyslipidemia and related disorders

(2009) Stefano Fiorucci et al.   PROGRESS IN LIPID RESEARCH

Compensatory Induction of Liver Efflux Transporters in Response to ANIT-Induced Liver Injury Is Impaired in FXR-Null Mice

(2009) Yue J. Cui et al.   TOXICOLOGICAL SCIENCES

Decreased apoptosis during CAR-mediated hepatoprotection against lithocholic acid-induced liver injury in mice

(2009) Lisa D. Beilke et al.   TOXICOLOGY LETTERS

PXR and CAR in energy metabolism

(2009) Taira Wada et al.   TRENDS IN ENDOCRINOLOGY AND METABOLISM

β-Klotho and FGF-15/19 inhibit the apical sodium-dependent bile acid transporter in enterocytes and cholangiocytes

(2008) Jyoti Sinha et al.   AMERICAN JOURNAL OF PHYSIOLOGY-GASTROINTESTINAL AND LIVER PHYSIOLOGY

Mechanism of Vitamin D Receptor Inhibition of Cholesterol 7 -Hydroxylase Gene Transcription in Human Hepatocytes

(2008) S. Han et al.   DRUG METABOLISM AND DISPOSITION

Bile acids activate fibroblast growth factor 19 signaling in human hepatocytes to inhibit cholesterol 7α-hydroxylase gene expression

(2008) Kwang-Hoon Song et al.   HEPATOLOGY

High expression of the bile salt-homeostatic hormone fibroblast growth factor 19 in the liver of patients with extrahepatic cholestasis

(2008) Frank G. Schaap et al.   HEPATOLOGY

Vitamin D3 Modulates the Expression of Bile Acid Regulatory Genes and Represses Inflammation in Bile Duct-Ligated Mice

(2008) M. Ogura et al.   JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS

The organic solute transporter  - , Ost -Ost , is essential for intestinal bile acid transport and homeostasis

(2008) A. Rao et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA