Pharmacokinetic drug interactions involvingGinkgo biloba

Ginkgo biloba leaf extract (EGb 761®) and its specific acylated flavonol constituents increase dopamine and acetylcholine levels in the rat medial prefrontal cortex: possible implications for the cognitive enhancing properties of EGb 761®

(2012) J. Kehr et al.   INTERNATIONAL PSYCHOGERIATRICS

Ginkgo biloba extract EGb 761® in dementia with neuropsychiatric features: A randomised, placebo-controlled trial to confirm the efficacy and safety of a daily dose of 240 mg

(2012) Horst Herrschaft et al.   JOURNAL OF PSYCHIATRIC RESEARCH

Dietary Supplements: Safety Issues and Quality Control

(2011) James K. Glisson   ARCHIVES OF INTERNAL MEDICINE

Flavonoid modulation of GABAA receptors

(2011) Jane R. Hanrahan et al.   BRITISH JOURNAL OF PHARMACOLOGY

Digoxin Is Not a Substrate for Organic Anion-Transporting Polypeptide Transporters OATP1A2, OATP1B1, OATP1B3, and OATP2B1 but Is a Substrate for a Sodium-Dependent Transporter Expressed in HEK293 Cells

(2011) M. E. Taub et al.   DRUG METABOLISM AND DISPOSITION

Effect of Ginkgo biloba special extract EGb 761® on human cytochrome P450 activity: a cocktail interaction study in healthy volunteers

(2011) G. Zadoyan et al.   EUROPEAN JOURNAL OF CLINICAL PHARMACOLOGY

Cytochrome P450 2C9 mediated metabolism in people with and without cancer

(2011) S.S. Shord et al.   INTERNATIONAL JOURNAL OF CLINICAL PHARMACOLOGY AND THERAPEUTICS

Identification of novel pregnane X receptor activators from traditional Chinese medicines

(2011) Chunna Yu et al.   JOURNAL OF ETHNOPHARMACOLOGY

Differential Effect of Grapefruit Juice on Intestinal Absorption of Statins Due to Inhibition of Organic Anion Transporting Polypeptide and/or P-glycoprotein

(2011) Yoshiyuki Shirasaka et al.   JOURNAL OF PHARMACEUTICAL SCIENCES

Effects ofGinkgo bilobaextract on the pharmacokinetics and pharmacodynamics of tolbutamide in protein-restricted rats

(2011) Yuko Taki et al.   JOURNAL OF PHARMACY AND PHARMACOLOGY

Inhibition of Human UGT2B7 Gene Expression in Transgenic Mice by the Constitutive Androstane Receptor

(2011) M. F. Yueh et al.   MOLECULAR PHARMACOLOGY

Flavonoids and the CNS

(2011) Anna Jäger et al.   MOLECULES

Ginkgo biloba extract attenuates warfarin-mediated anticoagulation through induction of hepatic cytochrome P450 enzymes by bilobalide in mice

(2011) Yuko Taki et al.   PHYTOMEDICINE

Pharmakokinetische Arzneimittelinteraktionen zwischen Tumortherapeutika und Arzneimitteln der Komplementären Medizin: Mechanismen und klinische Relevanz

(2011) Matthias Unger   FORSCHENDE KOMPLEMENTARMEDIZIN

Simultaneous chemical fingerprint and quantitative analysis of Ginkgo biloba extract by HPLC–DAD

(2010) Daoquan Tang et al.   ANALYTICAL AND BIOANALYTICAL CHEMISTRY

Influence of the flavonoids apigenin, kaempferol, and quercetin on the function of organic anion transporting polypeptides 1A2 and 2B1

(2010) Kathrin Mandery et al.   BIOCHEMICAL PHARMACOLOGY

Evaluation of In Vivo P-Glycoprotein Phenotyping Probes

(2010) Joseph D. Ma et al.   CLINICAL PHARMACOKINETICS

Influence of Ginkgo biloba extract on the pharmacodynamic effects and pharmacokinetic properties of ticlopidine: An open-label, randomized, two-period, two-treatment, two-sequence, single-dose crossover study in healthy Korean male volunteers

(2010) Bo-Hyung Kim et al.   CLINICAL THERAPEUTICS

Characterization of Digoxin Uptake in Sandwich-Cultured Human Hepatocytes

(2010) E. Kimoto et al.   DRUG METABOLISM AND DISPOSITION

Efavirenz Primary and Secondary Metabolism In Vitro and In Vivo: Identification of Novel Metabolic Pathways and Cytochrome P450 2A6 as the Principal Catalyst of Efavirenz 7-Hydroxylation

(2010) E. T. Ogburn et al.   DRUG METABOLISM AND DISPOSITION

Effects of Ginkgo biloba extracts on diazepam metabolism: a pharmacokinetic study in healthy Chinese male subjects

(2010) Xiao-Cong Zuo et al.   EUROPEAN JOURNAL OF CLINICAL PHARMACOLOGY

Ginkgo biloba Extract in Alzheimer’s Disease: From Action Mechanisms to Medical Practice

(2010) Chun Shi et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Human Pregnane X Receptor Agonism by Ginkgo biloba Extract: Assessment of the Role of Individual Ginkgolides

(2010) A. J. Lau et al.   JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS

The effects of the SLCO2B1 c.1457C>T polymorphism and apple juice on the pharmacokinetics of fexofenadine and midazolam in humans

(2010) Junko Imanaga et al.   Pharmacogenetics and Genomics

Plasma Levels and Distribution of Flavonoids in Rat Brain after Single and Repeated Doses of StandardizedGinkgo bilobaExtract EGb 761®

(2010) Laura Rangel-Ordóñez et al.   PLANTA MEDICA

Interaction of Ginkgo biloba with efavirenz

(2009) Dirk-Jan Wiegman et al.   AIDS

Effects of Ginkgo biloba Extract Ingestion on the Pharmacokinetics of Talinolol in Healthy Chinese Volunteers

(2009) Lan Fan et al.   ANNALS OF PHARMACOTHERAPY

Lack of Effect of Ginkgo biloba on Voriconazole Pharmacokinetics in Chinese Volunteers Identified as CYP2C19 Poor and Extensive Metabolizers

(2009) He-Ping Lei et al.   ANNALS OF PHARMACOTHERAPY

Effects ofSchisandra sphenantheraextract on the pharmacokinetics of midazolam in healthy volunteers

(2009) Hua-Wen Xin et al.   BRITISH JOURNAL OF CLINICAL PHARMACOLOGY

Effects ofGinkgo bilobaextract on the pharmacokinetics of bupropion in healthy volunteers

(2009) He-Ping Lei et al.   BRITISH JOURNAL OF CLINICAL PHARMACOLOGY

Impact of OATP transporters on pharmacokinetics

(2009) A Kalliokoski et al.   BRITISH JOURNAL OF PHARMACOLOGY

Endogenous cortisol 6β-hydroxylation clearance is not an accurate probe for overall cytochrome P450 3A phenotyping in humans

(2009) Zhe-Yi Hu et al.   CLINICA CHIMICA ACTA

Effects of Dietary Factors on Drug Transport and Metabolism: The Impact on Dosage Guidelines in Transplant Patients

(2009) R Nowack et al.   CLINICAL PHARMACOLOGY & THERAPEUTICS

The Role of Organic Anion–Transporting Polypeptides and Their Common Genetic Variants in Mycophenolic Acid Pharmacokinetics

(2009) N Picard et al.   CLINICAL PHARMACOLOGY & THERAPEUTICS

Inhibition of Intestinal and Hepatic Glucuronidation of Mycophenolic Acid by Ginkgo biloba Extract and Flavonoids

(2009) M.-E. F. Mohamed et al.   DRUG METABOLISM AND DISPOSITION

Chemical analysis and quality control of Ginkgo biloba leaves, extracts, and phytopharmaceuticals

(2009) Teris A. van Beek et al.   JOURNAL OF CHROMATOGRAPHY A

Time-Dependent Induction of Hepatic Cytochrome P450 Enzyme Activity and mRNA Expression by Bilobalide in Rats

(2009) Yuko Taki et al.   JOURNAL OF PHARMACOLOGICAL SCIENCES

Transcriptional Activation of PPARα by Phenobarbital in the Absence of CAR and PXR

(2009) Viola Tamasi et al.   MOLECULAR PHARMACEUTICS

The Drug Transporter−Metabolism Alliance: Uncovering and Defining the Interplay

(2009) Leslie Z. Benet   MOLECULAR PHARMACEUTICS

Identification of pregnane-X receptor target genes and coactivator and corepressor binding to promoter elements in human hepatocytes

(2009) Niresh Hariparsad et al.   NUCLEIC ACIDS RESEARCH

Pharmacokinetics of bilobalide, ginkgolide A and B after administration of three differentGinkgo bilobaL. preparations in humans

(2009) Karin Woelkart et al.   PHYTOTHERAPY RESEARCH

Effect ofSchisandra chinensisextract andGinkgo bilobaextract on the pharmacokinetics of talinolol in healthy volunteers

(2009) L. Fan et al.   XENOBIOTICA

Acetaminophen bioactivation by human cytochrome P450 enzymes and animal microsomes

(2009) J. E. Laine et al.   XENOBIOTICA

Identification of ginkgolide B metabolites in urine and rat liver cytochrome P450 enzymes responsible for their formation in vitro

(2008) Dian-lei WANG et al.   ACTA PHARMACOLOGICA SINICA

In vitro Inhibition of CYP3A4 Metabolism and P-Glycoprotein-Mediated Transport by Trade Herbal Products

(2008) Bent H. Hellum et al.   BASIC & CLINICAL PHARMACOLOGY & TOXICOLOGY

Inhibition of P-glycoprotein and multidrug resistance protein 1 by dietary phytochemicals

(2008) Tomohiro Nabekura et al.   CANCER CHEMOTHERAPY AND PHARMACOLOGY

Effect of Ginkgo biloba extract on lopinavir, midazolam and fexofenadine pharmacokinetics in healthy subjects

(2008) Sarah M. Robertson et al.   CURRENT MEDICAL RESEARCH AND OPINION

Identification of Ginkgo biloba as a Novel Activator of Pregnane X Receptor

(2008) E. Y. H. Yeung et al.   DRUG METABOLISM AND DISPOSITION

Effect of Aging on Glucuronidation of Valproic Acid in Human Liver Microsomes and the Role of UDP-Glucuronosyltransferase UGT1A4, UGT1A8, and UGT1A10

(2008) U. A. Argikar et al.   DRUG METABOLISM AND DISPOSITION

Mechanism-Based Inactivation of Cytochrome P450 2C9 by Tienilic Acid and ( )-Suprofen: A Comparison of Kinetics and Probe Substrate Selection

(2008) J. M. Hutzler et al.   DRUG METABOLISM AND DISPOSITION

Biology and chemistry of Ginkgo biloba

(2008) Bikram Singh et al.   FITOTERAPIA

Ginkgo biloba for Prevention of DementiaA Randomized Controlled Trial

(2008) Steven T. DeKosky   JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION

Activation of Pregnane X Receptor and Induction of MDR1 by Dietary Phytochemicals

(2008) Hideo Satsu et al.   JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY

Simultaneous determination of ginkgolides A, B, C and bilobalide in plasma by LC–MS/MS and its application to the pharmacokinetic study of Ginkgo biloba extract in rats

(2008) Jiashu Xie et al.   JOURNAL OF CHROMATOGRAPHY B-ANALYTICAL TECHNOLOGIES IN THE BIOMEDICAL AND LIFE SCIENCES

CYP2C19Genotype Is a Major Factor Contributing to the Highly Variable Pharmacokinetics of Voriconazole

(2008) Johanna Weiss et al.   JOURNAL OF CLINICAL PHARMACOLOGY

Clinical assessment of CYP2D6‐mediated herb–drug interactions in humans: Effects of milk thistle, black cohosh, goldenseal, kava kava, St. John's wort, andEchinacea

(2008) Bill J. Gurley et al.   MOLECULAR NUTRITION & FOOD RESEARCH

Involvement of Multiple Efflux Transporters in Hepatic Disposition of Fexofenadine

(2008) S. Matsushima et al.   MOLECULAR PHARMACOLOGY

Bioactive Terpenoids and Flavonoids from Ginkgo Biloba Extract Induce the Expression of Hepatic Drug-Metabolizing Enzymes Through Pregnane X Receptor, Constitutive Androstane Receptor, and Aryl hydrocarbon Receptor-Mediated Pathways

(2008) Linhao Li et al.   PHARMACEUTICAL RESEARCH

Influence of Drug Transporters and UGT Polymorphisms on Pharmacokinetics of Phenolic glucuronide Metabolite of Mycophenolic Acid in Japanese Renal Transplant Recipients

(2008) Masatomo Miura et al.   THERAPEUTIC DRUG MONITORING

The impact of P-glycoprotein and Mrp2 on mycophenolic acid levels in mice

(2008) Jian Wang et al.   TRANSPLANT IMMUNOLOGY

Induction of cytochrome P450s by terpene trilactones and flavonoids of theGinkgo bilobaextract EGb 761 in rats

(2008) Y. Deng et al.   XENOBIOTICA

The Tangle of Nuclear Receptors that Controls Xenobiotic Metabolism and Transport: Crosstalk and Consequences

(2007) Jean-Marc Pascussi et al.   Annual Review of Pharmacology and Toxicology